Bordetella pertussis 137: Q425_33450
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Entry
Q425_33450 CDS
T03754
Symbol
cyaA
Name
(GenBank) bifunctional hemolysin-adenylate cyclase
KO
K22944
bifunctional hemolysin/adenylate cyclase [EC:
4.6.1.1
]
Organism
bpeu
Bordetella pertussis 137
Pathway
bpeu00230
Purine metabolism
bpeu05133
Pertussis
Module
bpeu_M00575
Pertussis pathogenicity signature, T1SS
Brite
KEGG Orthology (KO) [BR:
bpeu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Q425_33450 (cyaA)
09160 Human Diseases
09171 Infectious disease: bacterial
05133 Pertussis
Q425_33450 (cyaA)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02042 Bacterial toxins [BR:
bpeu02042
]
Q425_33450 (cyaA)
Enzymes [BR:
bpeu01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
Q425_33450 (cyaA)
Bacterial toxins [BR:
bpeu02042
]
Type III toxins: Intracellular toxins
Adenylate cyclase
Adenylate cyclase toxin (ACT)
Q425_33450 (cyaA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RTX
Anthrax_toxA
HemolysinCabind
HCBP_related
TPR_Trm732_C
Motif
Other DBs
NCBI-ProteinID:
AJB27830
LinkDB
All DBs
Position
3534390..3539510
Genome browser
AA seq
1706 aa
AA seq
DB search
MQQSHQAGYANAADRESGIPAAVLDGIKAVAKEKNATLMFRLVNPHSTSLIAEGVATKGL
GVHAKSSDWGLQAGYIPVNPNLSKLFGRAPEVIARADNDVNSSLAHGHTAVDLTLSKERL
DYLRQAGLVTGMADGVVASNHAGYEQFEFRVKETSDGRYAVQYRRKGGDDFEAVKVIGNA
AGIPLTADIDMFAIMPHLSNFRDSARSSVTSGDSVTDYLARTRRAASEATGGLDRERIDL
LWKIARAGARSAVGTEARRQFRYDGDMNIGVITDFELEVRNALNRRAHAVGAQDVVQHGT
EQNNPFPEADEKIFVVSATGESQMLTRGQLKEYIGQQRGEGYVFYENRAYGVAGKSLFDD
GLGAAPGVPSGRSKFSPDVLETVPASPGLRRPSLGAVERQDSGYDSLDGVGSRSFSLGEV
SDMAAVEAAELEMTRQVLHAGARQDDAEPGVSGASAHWGQRALQGAQAVAAAQRLVHAIA
LMTQFGRAGSTNTPQEAASLSAAVFGLGEASSAVAETVSGFFRGSSRWAGGFGVAGGAMA
LGGGIAAAVGAGMSLTDDAPAGQKAAAGAEIALQLTGGTVELASSIALALAAARGVTSGL
QVAGASAGAAAGALAAALSPMEIYGLVQQSHYADQLDKLAQESSAYGYEGDALLAQLYRD
KTAAEGAVAGVSAVLSTVGAAVSIAAAASVVGAPVAVVTSLLTGALNGILRGVQQPIIEK
LANDYARKIDELGGPQAYFEKNLQARHEQLANSDGLRKMLADLQAGWNASSVIGVQTTEI
SKSALELAAITGNADNLKSVDVFVDRFVQGERVAGQPVVLDVAAGGIDIASRKGERPALT
FITPLAAPGEEQRRRTKTGKSEFTTFVEIVGKQDRWRIRDGAADTTIDLAKMVSQLVDAN
GVLKHSIKLDVIGGDGDDVVLANASRIHYDGGAGTNTVSYAALGRQDSITVSADGERFNV
RKQLNNANVYREGVATQTTAYGKRTENVQYRHVELARVGQLVEVDTLEHVQHIIGGAGND
SITGNAHDNFLAGGSGDDRLDGGAGNDTLVGGEGQNTVIGGAGDDVFLQDLGVWSNQLDG
GAGVDTVKYNVHQPSEERLERMGDTGIHADLQKGTVEKWPALNLFSVDHVKNIENLHGSR
LNDRIAGDDQDNELWGHDGNDTIRGRGGDDILRGGLGLDTLYGEDGNDIFLQDDETVSDD
IDGGAGLDTVDYSAMIHPGRIVAPHEYGFGIEADLSREWVRKASALGVDYYDNVRNVENV
IGTSMKDVLIGDAQANTLMGQGGDDTVRGGDGDDLLFGGDGNDMLYGDAGNDTLYGGLGD
DTLEGGAGNDWFGQTQAREHDVLRGGDGVDTVDYSQTGAHAGIAAGRIGLGILADLGAGR
VDKLGEAGSSAYDTVSGIENVVGTELADRITGDAQANVLRGAGGADVLAGGEGDDVLLGG
DGDDQLSGDAGRDRLYGEAGDDWFFQDAANAGNLLDGGDGRDTVDFSGPGRGLDAGAKGV
FLSLGKGFASLMDEPETSNVLRNIENAVGSARDDVLIGDAGANVLNGLAGNDVLSGGAGD
DVLLGDEGSDLLSGDAGNDDLFGGQGDDTYLFGVGYGHDTIYESGGGHDTIRINAGADQL
WFARQGNDLEIRILGTDDALTVHDWYRDADHRVEIIHAANQAVDQAGIEKLVEAMAQYPD
PGAAAAAPPAARVPDTLMQSLAVNWR
NT seq
5121 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaatcgcatcaggctggttacgcaaacgccgccgaccgggagtctggcatcccc
gcagccgtactcgatggcatcaaggccgtggcgaaggaaaaaaacgccacattgatgttc
cgcctggtcaacccccattccaccagcctgattgccgaaggggtggccaccaaaggattg
ggcgtgcacgccaagtcgtccgattgggggttgcaggcgggctacattcccgtcaacccg
aatctttccaaactgttcggccgtgcgcccgaggtgatcgcgcgggccgacaacgacgtc
aacagcagcctggcgcatggccataccgcggtcgacctgacgctgtcgaaagagcggctt
gactatctgcggcaagcgggcctggtcaccggcatggccgatggcgtggtcgcgagcaac
cacgcaggctacgagcagttcgagtttcgcgtgaaggaaacctcggacgggcgctatgcc
gtgcagtatcgccgcaagggcggcgacgatttcgaggcggtcaaggtgatcggcaatgcc
gccggtattccactgacggcggatatcgacatgttcgccattatgccgcatctgtccaac
ttccgcgactcggcgcgcagttcggtgaccagcggcgattcggtgaccgattacctggcg
cgcacgcggcgggccgccagcgaggccacgggcggcctggatcgcgaacgcatcgacttg
ttgtggaaaatcgctcgcgccggcgcccgttccgcagtgggcaccgaggcgcgtcgccag
ttccgctacgacggcgacatgaatatcggcgtgatcaccgatttcgagctggaagtgcgc
aatgcgctgaacaggcgggcgcacgccgtcggcgcgcaggacgtggtccagcatggcact
gagcagaacaatcctttcccggaggcagatgagaagattttcgtcgtatcggccaccggt
gaaagccagatgctcacgcgcgggcaactgaaggaatacattggccagcagcgcggcgag
ggctatgtcttctacgagaaccgtgcatacggcgtggcggggaaaagcctgttcgacgat
gggctgggagccgcgcccggcgtgccgagcggacgttcgaagttctcgccggatgtactg
gaaacggtgccggcgtcacccggattgcggcggccgtcgctgggcgcagtggaacgccag
gattccggctatgacagccttgatggggtgggatcgcgatcgttctcgttgggcgaggtg
tccgacatggccgccgtggaagcggcggaactggaaatgacccggcaagtcttgcacgcc
ggggcgcggcaggacgatgccgagccgggcgtgagcggtgcgtcggcgcactgggggcag
cgggcgctgcagggcgcccaggcggtggcggcggcgcagcggctggttcatgccattgcc
ctgatgacgcaattcggccgggccggttccaccaacacgccgcaggaagcggcctcgttg
tcggcggccgtgttcggcttgggcgaggccagcagcgccgtggccgaaaccgtgagcggt
tttttccgcgggtcttcgcgctgggccggcggtttcggcgtggctggcggcgcgatggcg
ctgggaggcggcatcgccgcggccgttggcgccgggatgtcgttgaccgatgacgcgccg
gccggacagaaggccgccgccggcgccgagatcgcgctgcagttgacaggtggaacggtc
gagctggcttcttccatcgcgttggcgctggccgcggcgcgcggcgtgaccagcggcttg
caggtggccggggcgtcggccggggcggctgccggcgcattggccgcggcgctcagtccc
atggagatctacggcctggtgcagcaatcgcactatgcggatcagctggacaagctggcg
caggaatcgagcgcatacggttacgagggcgacgccttgctggcccagctgtatcgcgac
aagacggccgccgagggcgccgtcgccggcgtctccgccgtcctgagcacggtgggggcg
gcggtgtcgatcgccgcggcggccagcgtggtaggggccccggtggcggtggtcacttcc
ttgctgaccggggctctcaacggcatcctgcgcggcgtgcagcagcccatcatcgaaaag
ctggccaacgattacgctcgcaagatcgacgagctgggcgggccgcaagcgtacttcgag
aaaaacctgcaggcgcgtcacgaacaactggccaattcggacggcctacggaaaatgctg
gccgacctgcaggccggttggaacgccagcagcgtgatcggggtgcagacgacagagatc
tccaagtcggcgctcgaactggccgccattaccggcaacgcggacaacctgaaatccgtc
gacgtgttcgtggaccgcttcgtccagggcgagcgggtggccggccagccggtggtcctc
gacgtcgccgccggcggcatcgatatcgccagccgcaagggcgagcggccggcgctgacg
ttcatcacgccgctggccgcgccaggagaagagcagcgccggcgcacgaaaacgggcaag
agcgaattcaccacattcgtcgagatcgtgggcaagcaggaccgctggcgcatccgggac
ggcgcggccgacaccaccatcgatctggccaagatggtgtcgcaactggtcgacgccaat
ggcgtgctcaagcacagcatcaaactggatgtgatcggcggagatggcgatgacgtcgtg
cttgccaatgcttcgcgcatccattatgacggcggcgcgggcaccaacacggtcagctat
gccgccctgggtcgacaggattccattaccgtgtccgccgacggggaacgtttcaacgtg
cgcaagcagttgaacaacgccaacgtgtatcgcgaaggcgtggctacccagacaaccgcc
tacggcaagcgcacggagaatgtccaataccgccatgtcgagctggcccgtgtcgggcaa
ctggtggaggtcgacacgctcgagcatgtgcagcacatcatcggcggggccggcaacgat
tcgatcaccggcaatgcgcacgacaacttcctagccggcgggtcgggcgacgacaggctg
gatggcggcgccggcaacgacaccctggttggcggcgagggccaaaacacggtcatcggc
ggcgccggcgacgacgtattcctgcaggacctgggggtatggagcaaccagctcgatggc
ggcgcgggcgtcgataccgtgaagtacaacgtgcaccagccttccgaggagcgcctcgaa
cgcatgggcgacacgggcatccatgccgatcttcaaaagggcacggtcgagaagtggccg
gccctgaacctgttcagcgtcgaccatgtcaagaatatcgagaatctgcacggctcccgc
ctgaacgaccgcatcgccggcgacgaccaggacaacgagctctggggccacgatggcaac
gacacgatacgcggccggggcggcgacgacatcctgcgcggcggcctgggcctggacacg
ctgtatggcgaggacggcaacgacatcttcctgcaggacgacgagaccgtcagcgatgac
atcgacggcggcgcggggctggacaccgtcgactactccgccatgatccatccaggcagg
atcgttgcgccgcatgaatacggcttcgggatcgaggcggacctgtccagggaatgggtg
cgcaaggcgtccgcgctgggcgtggactattacgataatgtccgcaatgtcgaaaacgtc
atcggtacgagcatgaaggatgtgctcatcggcgacgcgcaagccaataccctgatgggc
cagggcggcgacgataccgtgcgcggcggcgacggcgatgatctgctgttcggcggcgac
ggcaacgacatgctgtatggcgacgccggcaacgacaccctctacggggggctgggcgac
gatacccttgaaggcggcgcgggcaacgattggttcggccagacgcaggcgcgcgagcat
gacgtgctgcgcggcggagatggggtggataccgtcgattacagccagaccggcgcgcat
gccggcattgccgcgggtcgcatcgggctgggcatcctggctgacctgggcgccggccgc
gtcgacaagctgggcgaggccggcagcagcgcctacgatacggtttccggtatcgagaac
gtggtgggcacggaactggccgaccgcatcacgggcgatgcgcaggccaacgtgctgcgc
ggcgcgggtggcgccgacgtgcttgcgggcggcgagggcgacgatgtgctgctgggcggc
gacggcgacgaccagctgtcgggcgacgccggacgcgatcgcttgtacggcgaagccggt
gacgactggttcttccaggatgccgccaatgccggcaatctgctcgacggcggcgacggc
cgcgataccgtggatttcagcggcccgggccggggcctcgacgccggcgcaaagggcgta
ttcctgagcttgggcaaggggttcgccagcctgatggacgaacccgaaaccagcaacgtg
ttgcgcaatatcgagaacgccgtgggcagcgcgcgtgatgacgtgctgatcggcgacgca
ggcgccaacgtcctcaatggcctggcgggcaacgacgtgctgtccggcggcgctggcgac
gatgtgctgctgggcgacgagggctcggacctgctcagcggcgatgcgggcaacgacgat
ctgttcggcgggcagggcgatgatacttatctgttcggggtcgggtacgggcacgacacg
atctacgaatcgggcggcggccatgacaccatccgcatcaacgcgggggcggaccagctg
tggttcgcgcgccagggcaacgacctggagatccgcattctcggcaccgacgatgcactt
accgtgcacgactggtatcgcgacgccgatcaccgggtggaaatcatccatgccgccaac
caggcggtagaccaggcaggcatcgaaaagctggtcgaggcaatggcgcagtatccggac
cccggcgcggcggcggctgccccgccggcggcgcgcgtgccggacacgctgatgcagtcc
ctggctgtcaactggcgctga
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