Burkholderia pseudomallei 1710b: BURPS1710b_0734
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Entry
BURPS1710b_0734 CDS
T00289
Symbol
leuA
Name
(GenBank) hydroxymethylglutaryl-CoA lyase-like protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bpm
Burkholderia pseudomallei 1710b
Pathway
bpm00290
Valine, leucine and isoleucine biosynthesis
bpm00620
Pyruvate metabolism
bpm01100
Metabolic pathways
bpm01110
Biosynthesis of secondary metabolites
bpm01210
2-Oxocarboxylic acid metabolism
bpm01230
Biosynthesis of amino acids
Module
bpm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bpm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BURPS1710b_0734 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BURPS1710b_0734 (leuA)
Enzymes [BR:
bpm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BURPS1710b_0734 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
BP74_N
Motif
Other DBs
NCBI-ProteinID:
ABA49590
UniProt:
Q3JWA5
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All DBs
Position
I:complement(748039..749679)
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AA seq
546 aa
AA seq
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MKRNPAEKYRPFEPVRINGRRWPSRAIERAPIWMSTDLRDGNQSLIEPMTIEQKLEYFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIVERRIPDDVTIEVLVQSREDLIARTFDALEGA
PRAIVHLYNAICPSFRRIVFGMSQDDVKALAVDGTRIIKAHAQARPATHWTFQYSPETFS
MTELPFAREVCDAVAQTWRPTRDHKMIVNLPATVEAATPNVFADQIEWMDRNLGYRDSIV
LSVHPHNDRGTAVAAAELALLAGAERIEGCLFGNGERTGNVDLVTLALNLYTQGIDPGLD
FSDIDAVRRVVERCNRIPVHPRHPYAGDLVFTAFSGSHQDAIRKGLAQQRPDAIWEVPYL
PIDPADLGRSYDAVIRVNSQSGKGGATYLLERAMGFAPPRRVQIEFSHAVQTLADTSGAE
VTADAICALFTREYLQTIGPAARAGASASWHDREVALAHAEDAPSAARQAAAAFASAAGV
AIDITSCEVERTVNGETAVFVGARIGDAALRHGAGVHRDPVAAATDAVASAINRSAWSRD
KRRAAA
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgcaaccccgccgagaaataccgaccgttcgaacccgttcgcatcaacggacgc
cgatggccgagccgcgcgatcgagcgcgcgccgatctggatgagcaccgatctgcgcgac
ggcaaccagtcgctgatcgagccgatgacgatcgagcagaagctcgaatacttcgagatg
ctcgtcgcgatcggcttcaaggaaatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtgcgcaagctgatcgtcgagcggcgcattcccgacgatgtgacgatcgaa
gtgctcgtgcaatcgcgcgaagacctgatcgcgcgcacgttcgacgcgctcgaaggcgcg
ccgcgcgcgatcgtccacctgtacaacgcgatctgcccgtcgttccgccggatcgtgttc
gggatgtcgcaggacgacgtgaaggcgctcgcggtggacggcacgcggatcatcaaggcg
cacgcgcaggcgcgccccgccacccactggacgttccagtactcgcccgagacgttcagc
atgaccgagctgccgttcgcgcgcgaggtctgcgacgccgtcgcgcagacgtggcggccg
acgcgcgatcacaagatgatcgtgaacctgcccgccaccgtcgaggccgcgacgccgaac
gtgttcgccgaccagatcgaatggatggaccgcaatctcggctatcgcgacagcatcgtg
ctgtccgtgcatccgcacaacgaccgcggcacggcggtcgcggcggccgagctcgcgttg
ctcgcgggcgcggagcgcatcgaaggatgcctgttcggcaacggcgagcgcacgggcaac
gtcgatctcgtcacgctcgcgctgaacctgtacacgcaggggatcgatccgggcctcgat
ttctccgatatcgacgcggtgcgccgcgtcgtcgagcgctgcaaccggattcccgtgcat
ccgcgccatccgtacgcgggcgacctcgtgttcaccgcgttctccggctcgcatcaggac
gcgatccgcaagggcctcgcgcagcagcggcccgatgcgatctgggaagtgccgtacctg
ccgatcgatcccgccgacctcggccgcagctacgacgcggtgatccgcgtgaacagccag
tccggcaagggcggcgcgacctatctgctcgagcgcgcaatgggtttcgcgccgccgcgc
cgcgtgcagatcgaattcagccatgcggtgcaaacgctcgccgacacgtccggcgcagag
gtgacggccgatgcgatttgcgcgctcttcacgcgcgaatatctgcagacgatcggcccg
gccgcgcgcgcgggcgcgtcggcgagctggcacgatcgcgaagtcgcgctcgcgcacgcc
gaggatgcgccgagcgcggcgcggcaggcggcggccgcgttcgcgtcggccgcgggcgtc
gcgatcgacatcacgtcgtgcgaggtcgagcgcaccgtgaacggcgagaccgccgtgttc
gtcggcgcgaggatcggcgacgccgcgttgcgccacggcgcgggcgtgcatcgcgacccg
gtcgcggccgcgacggacgccgtcgcgagcgcgatcaaccgctcggcgtggagccgagac
aagcggcgcgccgcggcctga
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