Burkholderia pseudomallei HBPUB10134a: DR55_5457
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Entry
DR55_5457 CDS
T03422
Symbol
bkdA1
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bpsh
Burkholderia pseudomallei HBPUB10134a
Pathway
bpsh00280
Valine, leucine and isoleucine degradation
bpsh00640
Propanoate metabolism
bpsh00785
Lipoic acid metabolism
bpsh01100
Metabolic pathways
bpsh01110
Biosynthesis of secondary metabolites
bpsh01210
2-Oxocarboxylic acid metabolism
Module
bpsh_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
bpsh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DR55_5457 (bkdA1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DR55_5457 (bkdA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DR55_5457 (bkdA1)
Enzymes [BR:
bpsh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DR55_5457 (bkdA1)
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Motif
Pfam:
E1_dh
OxoDH_E1alpha_N
TPP_enzyme_C
DXP_synthase_N
LutB_C
Motif
Other DBs
NCBI-ProteinID:
AIP55354
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Position
2:2632998..2634230
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AA seq
410 aa
AA seq
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MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDE
HGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHT
LALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSI
SGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVV
NNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPT
LIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAA
LEAEVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
NT seq
1233 nt
NT seq
+upstream
nt +downstream
nt
atgagccagtacgggccattgcgattgcatgtgccggagcctaccgggcgtccgggatgc
aagaccgatttttcttacctgcgcctgtcgccagccggcaaggtgcgcaaaccccccatc
gacgtcgcccccgccgacacgagcgacttggcctatggcctcgtgcgcgtgctcgacgag
cacggacgagcggtcgggccatgggcgcccgacctcgatcccgacatcttgcgcaaaggc
atccgcgcgatgctgaagacgcgcatcttcgacgcgcgcatgcagatcgcgcagcgccag
aagaagatctcgttctacatgcagtgcctcggcgaggaagcgatcgcggtcgcgcacacg
ctcgcgctcgagcgcggcgacatgtgctttccgacgtatcggcagcaagggatcctgatg
gtgcgcgagtatccgctcgtcgacatgatgtgccagctgatgtcgaacgagcgcgatccg
ctgaagggccgccagttgccggtgatgtactcgacgcgcgacgcgggcttcttctcgatc
tcgggcaatctcgcgacgcagttcatccaggcggtcggctgggcgatggcctcggcgatc
aagggcgacacgcgcatcgcttccgcgtggatcggcgacggcgcgacggccgaagccgat
ttccataccgcgctcacgttcgcacacgtgtaccgcgcgcccgtgatcctgaacgtggtc
aacaaccagtgggcgatctcgacgttccaggcgatcgcgggcggcgagggcgcgaccttc
gccgggcgcggcgtcggctgcggcatcgcttcgctgcgcgtggacggcaacgatttcctc
gcggtctacgccgcgtcccgctgggcggccgaacgcgcgcgccgcaacctcgggccgacg
ctgatcgagtgggtcacgtaccgcgcgggcccgcactcgacgtccgacgatccgaccaag
taccgccccggcgacgactggacgaacttcccgctcggcgatccgctcgagcgcctgaag
cgccacatgatcggcatcggcgtgtggtccgagcaggaccacgaggacacgaaggccgcg
ctcgaggccgaggtgctcgccgcgcagaaggaagcggagcgctacggcacgctggccgac
gagcacgtgccgaacgtcgcgagcattttcgaggacgtctacaaggagatgcccgcgcac
ctgcgccggcagcgccaacagctcggggtttga
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