Brachyspira pilosicoli WesB: WESB_1354
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Entry
WESB_1354 CDS
T02412
Symbol
murfF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-glutamyl-2,6-diaminopimelate-alanyl-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bpw
Brachyspira pilosicoli WesB
Pathway
bpw00300
Lysine biosynthesis
bpw00550
Peptidoglycan biosynthesis
bpw01100
Metabolic pathways
bpw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bpw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
WESB_1354 (murfF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
WESB_1354 (murfF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
WESB_1354 (murfF)
Enzymes [BR:
bpw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
WESB_1354 (murfF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MurT_C
Motif
Other DBs
NCBI-ProteinID:
CCG56822
UniProt:
K0JIW9
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All DBs
Position
complement(1484460..1485806)
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AA seq
448 aa
AA seq
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MGQTSLKDIIKIANETNSKCIFNSTDENKNLQISTDSREDFNENKLFLAIKGDKFNGNDF
ALDTYNKGCRFFILSENINMPKDANVVYTNDSVLFFIKLAREYRRRFNIKVVSITGSCGK
TTTKELTALFLGTKYKTLKTEGNFNNEIGVPKTIFNLDDSYEMAVIEAGMNHKNELLRIS
EAIEADTVIINNVEPVHIAFLGSLENIALAKSELFNNAKENAIINKNTNKVDILLSEAKN
KKIKNIIEADIKEIKKINDNSFVYKNVTFNHNLIGDFNLQNILMALKAAEIYDVDLEECA
KALTNYQNQKNRMQIIKINNCSIINDCYNSNPTALKNMLIYLSKREEKRKIAIIGDMLET
ETQNSSFHKDIGIFINSLKNINEVITVGDNSQKIDNEVTCSKMHFKKVEESINTIIDIIK
NSNEETAILIKASLGMRFNMIIEAINNI
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgggacaaacttctctaaaagatataataaaaatagcaaatgaaactaattcaaaatgt
atcttcaactctactgatgaaaataaaaatttacaaatatccacagacagtagagaagat
tttaatgaaaacaaattattcttagccataaaaggcgataagtttaacggcaatgatttt
gctttagatacatacaataaaggatgcagattttttatactttcagaaaatatcaatatg
ccaaaagacgctaatgtggtttatactaatgacagtgtattattttttataaagctggct
agagaatatagaagaagatttaatataaaagtagtatcaattacaggaagctgtggaaaa
actactacaaaagaattaacagcattatttttaggcacaaaatataaaacactaaaaaca
gaaggcaattttaataatgaaataggagtgccaaaaacaatatttaatttagatgacagt
tacgagatggcagtaatagaagctggaatgaatcataaaaatgaacttttaagaatatct
gaagcaatagaagctgatactgttattattaataatgttgaacctgtacatattgctttt
ttgggttctttagaaaatatagctcttgctaaaagtgagttatttaataatgcaaaagaa
aatgctattataaataaaaacacaaacaaagtagatatattattaagcgaagcaaaaaac
aaaaaaataaaaaatattatagaagcagacataaaagaaataaaaaagataaatgataac
agttttgtttataagaatgtaacattcaatcataatttaattggagattttaatttacaa
aatatattaatggctctaaaagcagcagagatttatgatgtagatttagaagaatgtgca
aaagctttaactaattatcaaaatcaaaaaaatagaatgcagataataaaaataaataac
tgctctattataaacgattgctacaattcaaaccctacagcattaaaaaatatgcttata
tatttatctaaaagagaagaaaaacgaaaaatagctattataggcgatatgcttgaaaca
gaaactcaaaactcttcttttcataaagatataggaatatttataaactcattaaaaaac
ataaatgaagttattacagtcggagataattctcaaaaaatagataatgaagttacatgc
tctaaaatgcattttaaaaaagtagaagagagtataaacactataattgatattataaaa
aacagtaatgaagagacagcaattttaataaaagcttcactaggtatgcgttttaatatg
ataatagaagcaataaataatatataa
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