Bacillus amyloliquefaciens LL3: LL3_00456
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Entry
LL3_00456 CDS
T01835
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bql
Bacillus amyloliquefaciens LL3
Pathway
bql00300
Lysine biosynthesis
bql00550
Peptidoglycan biosynthesis
bql01100
Metabolic pathways
bql01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bql00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LL3_00456 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LL3_00456 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LL3_00456 (murF)
Enzymes [BR:
bql01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LL3_00456 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEB62004
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Position
453606..454976
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AA seq
456 aa
AA seq
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MIKRTVKRIADMVKGTLTNPVFEQTMIEGAATDTRTLEKNQLFIPLKGEHFNGHTFVPQA
FEKGVSAVLWDRSEPNPPKERAVILVDDTLEALQKLAKAYLEELGTRVIGVTGSNGKTTT
KDMLHAVLGTQYRVHKTAGNFNNHIGLPLTVLAMPEDTEIAVLEMGMSARGEIDFLSRLA
EPEAAVITNIGESHMQDLGSREGIAEAKLEIINGLREDGVLFYFGDEPLLREKAYTCRTT
TYGEGADNDLRLKEIKQAEEGTYFTIDGIDRSFFIPVLGRHNVMNAMGAYAAGIYFGITP
ENAALGLSRLKVTGMRLELVKTENGISIVNDAYNASPTSMKAAIELIETMKGYRKKMLVL
GDMLELGDEEKAFHEECGAAINPAEIDHVFTYGTLGAFIADGARKHFEEGRVSHYLDKKE
LLEAIRENAASGDLLLFKASRGMKLEETVKDLLEKN
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
ttgataaagcgaactgtaaaacgaatcgccgacatggtcaaaggcacactgacaaatccc
gtatttgaacaaacaatgatagagggcgccgcaaccgatacgcggactttggaaaaaaat
cagctgttcatccctttaaaaggcgagcattttaacggccacacctttgtgccgcaagcc
ttcgaaaaaggcgtttccgccgtattgtgggaccgctccgaaccaaatccgccgaaagag
cgtgctgtcatccttgtcgatgatacgctggaggcgctgcaaaaattggcaaaagcttat
ttagaagagctcggcacacgggtcatcggggtgaccggaagcaacggaaaaacgacaaca
aaagacatgcttcacgctgtcctcggcactcaataccgcgttcacaaaactgccggcaat
tttaacaaccatatcggcctgccgctgaccgtgcttgccatgcctgaggatacggaaatt
gccgttttagaaatgggaatgagcgcgagaggcgaaattgattttctgagccgccttgct
gaaccggaagcggccgtcattaccaatatcggcgaatcccacatgcaggatttaggctca
agagaaggaattgcagaggcgaaacttgaaattataaacggacttcgggaagacggagtg
ctgttttatttcggggatgagccgctgctgcgcgagaaggcgtacacttgccggacaacg
acatacggcgaaggtgcggacaatgatctccgcttgaaagaaataaagcaggcagaagaa
ggcacatatttcactatcgacggtattgatcgttctttctttattcccgttctcggccgg
cataatgtgatgaacgccatgggcgcatacgccgccggcatctatttcggcattacgccg
gaaaatgcagctctgggactgagccgcctgaaggtgacgggaatgagattggaactggtc
aaaacggaaaacggcatctcaatcgtaaacgacgcctataatgcgagcccgacgtcaatg
aaagcggcgatcgaattaattgaaacgatgaaaggctatcgaaagaaaatgcttgttctc
ggtgatatgcttgaactcggtgatgaagaaaaagcattccacgaagaatgcggggccgcg
atcaatccggcggaaatcgaccatgtgtttacttacggcactctcggcgcattcattgct
gacggagcacgcaaacattttgaagagggccgcgtcagccattatcttgataaaaaagaa
ctgcttgaggctatccgggaaaatgccgcttcaggcgatctccttctgtttaaagcatca
agaggtatgaagcttgaagaaaccgttaaagatttattagagaagaactga
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