Brevibacillus sp. HD3.3A: HP435_09640
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Entry
HP435_09640 CDS
T10166
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
breh Brevibacillus sp. HD3.3A
Pathway
breh00790
Folate biosynthesis
breh01100
Metabolic pathways
breh01240
Biosynthesis of cofactors
Module
breh_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
breh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HP435_09640
Enzymes [BR:
breh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HP435_09640
6.3.2.17 tetrahydrofolate synthase
HP435_09640
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UED70878
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Position
1969297..1970670
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AA seq
457 aa
AA seq
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MHAEASFVEYKEALDWLHGLLRFGQRPGLERMQWVLEQLGHPERRIPFIHVAGTNGKGST
CAFLTQMLMEAGYSVGTFTSPYLLDFRERIRYNGSMISEADLLSLVNEVKVLSERCEQET
DFGSPTEFEVITLIAILYFSRVARPAVVVWETGLGGRLDSTNVVLPLVSVITNIGMDHTQ
VLGDTLQDIAREKAGIIKPGVPVITGETREEILAVFKERARETRSTLYSLREHFFAEQVE
EELGQQRFRYGSIHRRDESTYRLTMNGIHQTTNAAIALMTIDVLRNYFSFLLEEEEISRG
LQQTRWPGRLEVVSPRPLVILDGAHNQEGMEALAKSLERLLPNAAGLHLLFSGLADKPLS
EMAKALAPLKERIRSLYVTEFDFPRAADASTLREAFLQGGWSEENLEAVPDWQTFLLSWM
REKQSAKADDWLVVCGSLYFIAQVRAFFPTTVEEAGE
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgcatgcagaagcatcatttgttgaatacaaagaagcgctcgactggctgcatggactg
cttcgcttcggtcagcggccggggcttgagagaatgcagtgggtacttgagcaactgggt
catccggaacggagaatcccgtttattcatgtggcaggcaccaacggaaaaggctcgaca
tgcgcattcctgacgcaaatgctgatggaggcgggttacagtgtcgggacgttcacttcg
ccgtatttgctagatttccgcgagcgcattcgctacaacgggagcatgatcagcgaggct
gatctgctctcgctggtgaatgaagtgaaagtcttgagcgagcgctgcgagcaggagacg
gattttggctcgcctaccgaatttgaagtgattacgctgatcgccattctctatttttcg
agagtggcgcgaccagctgtcgttgtatgggaaacagggcttggcggtcggctcgattcg
accaatgtcgtcctgccgctcgtttctgtcatcacgaatatcggcatggatcatacacaa
gttttgggcgatacgctgcaggacatcgcccgtgaaaaagctggcatcatcaagccgggc
gtgcctgttatcactggcgagacacgagaggaaattctcgctgtgttcaaggagcgggct
cgcgagacgcgaagcacgctgtacagcctgcgcgagcatttttttgccgaacaggtagaa
gaagaactgggacagcagcgtttccgctacggcagcatccatcggcgcgatgaatctacc
tatcgtttgacgatgaacggcattcaccagacgacgaatgcagcgattgctctgatgacc
attgatgtcttgcgcaactatttttcgttcttgctggaagaagaagaaatatcgcgcggc
ttgcaacaaacacgctggcctggtcgtctagaagtcgtctcgccaagaccgcttgtgatc
ttggacggggcgcacaatcaggagggaatggaagcgctggccaaaagtctggagcggctt
ttgccgaacgctgcgggtctgcacctgctcttttccggcttggcggataaaccgctatcc
gagatggccaaagcactcgctcccctcaaggagcgaatccgatccttatacgtaacggaa
tttgactttccgcgtgcagcagatgcaagcacgctgcgcgaggcgtttttgcaaggtgga
tggtcagaggaaaacctcgaagccgtcccggactggcaaacgtttctcctttcttggatg
cgggagaagcaatcagcgaaagcggatgactggctggtcgtctgcggttcgctctacttc
atcgcccaagtgcgcgcattctttcccactacagtagaagaggcaggtgaatag
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