Brevibacillus sp. HD3.3A: HP435_10595
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Entry
HP435_10595 CDS
T10166
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
breh Brevibacillus sp. HD3.3A
Pathway
breh00300
Lysine biosynthesis
breh00550
Peptidoglycan biosynthesis
breh01100
Metabolic pathways
breh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
breh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HP435_10595
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HP435_10595
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HP435_10595
Enzymes [BR:
breh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HP435_10595
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2761
INTS7_HB
Motif
Other DBs
NCBI-ProteinID:
UED71056
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Position
complement(2159360..2160742)
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AA seq
460 aa
AA seq
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MKPLALEQATINAEGLLLAGSPHLVLSSVHFDTRQLKAGSLFVALTGGARDGHDFLLQAA
EQGAVAALVSNQEKIPAGLPEEFGLILVNDTLRGFQKLAAAYRKDFAIPHIAITGSIGKT
TVKDIVAHVLEARSPVYKTYKNLNNHLGVPLSLLQMEPQHQAAVLELGMNHAGEIDLLAS
LVKPEISVITYIGESHLEFFGTREKLALAKAELLPHTAPDGLVLLNKDSEYLPRVAHLYA
GEIMYYSVLEPCDIWAEHIQPNDNGTQFDVCFANGERFSAFLPLHGKHSVLNALPAIAIA
KRLGMDTEQIVQALSTVKLSAMRFEQVHSRHGSLYISDAYNASPSSMEAAARTFAELFPG
RKKVLVLGDMYEMGEQSAHMHAGVGEALNDLVEHIELLVTVGEDTQHLHRAYNGNKLHVA
SKPEALAALLPLRDASHAFLFKASRGMELWTLLTDLEQHE
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccacttgcactggaacaggcgacaatcaatgcagaaggactcttgctggcaggc
tctccgcaccttgtcttgtcatcggttcactttgatacccgccaactgaaagcgggttct
ttattcgtggcgctgacaggcggcgctcgcgatgggcacgattttttgctgcaagcagcc
gaacaaggagcggtagccgcactcgtatccaatcaggaaaaaattcccgctggcttgccc
gaggagttcgggctgattctcgtcaatgacacgctgcgcggttttcaaaagctggcagct
gcctatcggaaagactttgcgatcccgcatatcgcgattacgggcagcatcgggaaaacg
acggtgaaggacatcgtagctcacgtattggaagcgcgatcccctgtctacaagacatat
aaaaacttgaacaatcatttgggcgtgccgctttccttgctgcaaatggagccgcagcac
caggctgccgtgctggagctggggatgaatcacgccggagagatcgacttattggcttcg
ctcgtcaagccggagatcagcgtcattacgtatatcggcgagtcgcatctggagtttttc
ggcacgcgggaaaagcttgcgctcgccaaagccgagctgctcccccacaccgcccctgac
ggcctggttcttctcaacaaggactcggagtatttgccgcgagtggcccatctgtatgcc
ggggagatcatgtactattccgtgctggagccttgtgacatctgggcggaacatattcag
ccgaatgataatggaacacagtttgacgtctgcttcgcgaatggcgaacgcttctccgcc
tttctcccgcttcacggcaagcatagcgtgctgaacgcgcttcctgcgattgcgattgcg
aaaagactggggatggacacagaacaaatcgtgcaagcgctctccacggtcaagctctct
gccatgcggtttgaacaggtgcattccagacacggctccctgtatatcagcgatgcatac
aacgccagtccgtcttccatggaagctgctgcccggacgttcgccgagctgtttcctggc
cgcaaaaaagtgctcgtcttgggcgacatgtacgagatgggcgagcaaagcgctcacatg
cacgcaggagtcggcgaagcgctcaacgatcttgtcgagcacatcgagctgctcgtcacc
gttggcgaggatacgcaacatcttcatcgcgcctataacggcaacaagctgcatgtggca
agcaaaccggaggcgctcgccgcccttctgccattgcgcgatgccagccacgcctttttg
ttcaaagcgtcgcgcgggatggagctgtggacgcttttgactgatctggaacagcacgaa
tag
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