Brevibacillus sp. HD3.3A: HP435_13115
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Entry
HP435_13115 CDS
T10166
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
breh Brevibacillus sp. HD3.3A
Pathway
breh00290
Valine, leucine and isoleucine biosynthesis
breh00660
C5-Branched dibasic acid metabolism
breh01100
Metabolic pathways
breh01110
Biosynthesis of secondary metabolites
breh01210
2-Oxocarboxylic acid metabolism
breh01230
Biosynthesis of amino acids
Module
breh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
breh01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HP435_13115 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HP435_13115 (leuC)
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NCBI-ProteinID:
UED71522
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Position
complement(2644883..2646313)
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AA seq
476 aa
AA seq
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MKPRTMFEKIWDNHVIHEEAGKPSLLYIDLHLVHEVTSPQAFEGLRLAGRKVRRPELTFA
TMDHNVPTADRFNIKDPISRQQMETLTDNCREFGITLADLNSPDQGIVHVIGPELGLTHP
GKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLPQLKPKTMEVRVNGDLPFGVSA
KDLILAIIAKYGTDFATGYVVEYTGEAIRKLTMEERMTVCNMTIEGGARAGLIAPDQTTF
DYLQGRRYVPQGEDFLAAVEAWKELCTDEGATYDTCVEIDAAAIEPQVTWGTSPGMGTNI
TSTVPDPEAFETTAQRKAAQDALAYMDLAPGTPMSEIKIDRVFIGSCTNGRIEDLRKAAE
VAKGRKVSPSVHAMVVPGSQAVKQLAEQEGLHLIFQEAGFDWRESGCSMCLAMNPDILSE
GERCASTSNRNFEGRQGRGGRTHLVSPEMAAAAAIAGRFVDVREWKRESASEEVFQ
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccccgtacaatgtttgaaaagatttgggacaatcacgtgattcacgaggaagct
ggcaaaccgagccttttgtacattgatctgcatctggtgcacgaggtgacttctccgcaa
gcgtttgaagggctccgcctggctggccgcaaagtccgccgtccagaactgacttttgcc
accatggaccacaacgtgccgacagcggatcgcttcaatatcaaagacccgatctcccgt
cagcaaatggaaacactgactgataactgccgggaatttggcattacactcgctgacctg
aacagcccggatcaaggaatcgtccacgtcatcggccctgagcttggcctgacacatccc
ggcaaaacgatcgtgtgcggcgacagccacacttccacgcacggggcattcggcgccctc
gcctttgggatcgggacgagcgaggtcgaacacgtactcgccacacaatgcttgccgcag
ctgaagccaaaaacgatggaagtccgcgtgaacggcgacctgcctttcggtgtcagcgca
aaagacttaatattggcgattatcgcaaaatacggaactgactttgccaccgggtacgtc
gtagagtacacaggcgaagcgatccgcaagctgacaatggaagagcgcatgaccgtgtgc
aacatgacgattgaaggtggcgcacgcgccgggctgatcgctccggaccaaacgacgttt
gactatctgcaaggccgccgctacgttccgcaaggcgaagacttcctggcagcagtggaa
gcatggaaagagctgtgcacagacgaaggcgctacgtacgatacatgtgtcgaaatcgac
gccgctgccatcgaaccgcaagtgacatggggcaccagcccaggcatgggcacgaacatc
accagcacggttccagacccggaagcttttgagactacggcacagcgcaaagcggctcag
gacgctctcgcttacatggatcttgctccgggaacgcctatgagcgaaatcaaaatcgac
cgcgtcttcatcggctcctgtacaaacggacggattgaagacttgcgcaaagcggcggaa
gttgccaagggacgcaaagtctccccttccgtacacgcgatggtcgtacctggctcccag
gcagtcaagcagttggctgagcaagaaggcttgcacctcattttccaggaagccggtttc
gactggcgtgaatccggctgctccatgtgcctcgccatgaacccggatatcttgtcagaa
ggagagcgttgcgcttccacttccaaccgcaactttgaaggacgtcaaggccgtggcgga
cgcactcacctcgtcagcccggaaatggcagccgcggcagccatcgcaggccgcttcgta
gacgtacgtgaatggaaaagagagagcgcaagcgaggaggtattccaatga
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