Brevibacterium sp. JSBI002: LJ362_09985
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Entry
LJ362_09985 CDS
T10795
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
brej Brevibacterium sp. JSBI002
Pathway
brej00300
Lysine biosynthesis
brej00550
Peptidoglycan biosynthesis
brej01100
Metabolic pathways
brej01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
brej00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LJ362_09985
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LJ362_09985
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LJ362_09985
Enzymes [BR:
brej01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LJ362_09985
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Fib-H_N
Motif
Other DBs
NCBI-ProteinID:
UZD61028
UniProt:
A0A9E7VZ80
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Position
complement(2178716..2180182)
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AA seq
488 aa
AA seq
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MKRLTAAEIATALGGELYGIDPETPLTAGVVTDSREVGPGDIYVARRGESFDGIEFAAAA
VEAGAALIIGESVPTIDDEPLPVVVVADATEALGQLAKHSIEGLRTDGELTVIAITGSVG
KTTVKDLAADLLSGEAETVWPPNSYNNEVGVPLTALRAVESTRFLVLEMGARSIGNLAYL
TSLIRPDIAVELAVGTAHSGVFGSIENTARAKAELVESLTAGSTAVLNADDTRVSAMREV
LAPDVTTLWFSQRESLPEWVGGDDLVVRGTSVSTDSSGHPTFTLTLPGEEPRDVRLALIG
EHHVGNALAAAAIAHACGVAARSIVTTLSTSSAASRWRMELIDSPSGVTVLNDAYNANPE
SMRASLKTLASMGRGDEETSPRRTFAVLGEMLELGSESVSAHSDIGELVVRLNITRTIVV
GEGAKPIFNAANLEGSWGNEAAWVATAAEAKDLLNAELAPGDIVLFKSSRDAGLRYLGDE
IAGVSGAQ
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgaagcgactgactgcagccgaaatcgcaaccgccctgggcggcgagttgtacggcatc
gaccccgagaccccattgaccgccggtgtggtgaccgactcgagagaagtcggacccggc
gatatctacgtcgcccgccgaggcgagagcttcgacggcatcgaattcgccgccgccgcc
gtcgaggcgggagcggccctgatcatcggcgaatccgtccccaccatcgacgacgaacct
ctgccggtcgtcgtcgtcgccgatgccaccgaagcgctcggccagctggccaagcacagc
atcgaaggcctgcgcacagatggcgaactcactgtcatcgcgatcaccggatccgtcggc
aagaccacggtgaaggacctcgccgcggatctgctctcgggtgaggcggagaccgtgtgg
ccgccgaactcctacaacaacgaggtcggagtcccgctgacggctctgcgggcggtcgaa
tccacccgtttcctcgtcctcgagatgggggctcggtcgatcggcaacctcgcctatctg
acgagcctcatccgccccgacatcgcggtcgaactggccgtgggcaccgcccactccgga
gtcttcggttcgatcgagaacaccgcacgggccaaggccgaactcgtcgagtccctgaca
gccggatccaccgccgtgctcaatgccgacgacacccgcgtgtcggcgatgcgcgaggtg
ctcgctccagatgtcaccaccctgtggttctcacagcgtgagtccctgcccgaatgggtc
ggcggcgacgacctcgtcgtgcgcggcacctcggtgtccacggattcctccggtcatccg
acgttcaccctcaccctgcccggtgaggagccccgcgatgtgcgtctggcactcatcggc
gagcaccacgtcggcaacgctctcgcggcagccgccatcgcgcacgcctgcggcgtcgcg
gccaggtcgatcgtcaccaccctgtcgacctcctcggcggccagccgctggcggatggag
ctcatcgattcgccttcgggagtgaccgtgctcaacgacgcctacaatgcgaaccccgaa
tccatgcgggcctcgctgaagaccctggcctcgatgggccgcggtgatgaggagaccagc
ccgcgacgcaccttcgccgtgctcggcgagatgctcgaactcgggtccgaatcggtgtcc
gcgcactcggacatcggcgaactcgtcgtgcgcctcaacatcactcgcaccatcgtcgtg
ggagaaggcgcgaagccgatcttcaacgccgcgaacctcgaaggctcctggggcaacgag
gcggcctgggtcgccaccgcggccgaggcgaaggacttgctcaacgccgaactcgctccc
ggcgacatcgttctgttcaaatcctcccgcgacgccggtctgcgctacctgggagacgaa
atcgccggagtatcgggggcccaatga
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