KEGG   Brevundimonas sp. GW460-12-10-14-LB2: A4249_09680
Entry
A4249_09680       CDS       T04395                                 
Name
(GenBank) siroheme synthase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
brg  Brevundimonas sp. GW460-12-10-14-LB2
Pathway
brg00860  Porphyrin metabolism
brg01100  Metabolic pathways
brg01110  Biosynthesis of secondary metabolites
brg01120  Microbial metabolism in diverse environments
brg01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:brg00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    A4249_09680
Enzymes [BR:brg01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     A4249_09680
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     A4249_09680
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     A4249_09680
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M
Other DBs
NCBI-ProteinID: ANC53899
UniProt: A0A160HXW9
LinkDB
Position
complement(1929072..1930454)
AA seq 460 aa
MRVFLASIPLEAAKIVIIGGGEPALAKLRLFLNTPAEVVWFAPDGAPPKIETPLTAPEPV
LRAPEADELAGGRLVFMALDDADELTRLGHLARAAGAQVNVVDKPHLSDFQTPALIDRDE
VVIGVATGGSAPILARDIRTAIEGVLPAGLANVARLARELRDTVKASVPDFMARRRFWEK
AFRGPAATLAAEGRTAEARREMLRLLNTAAPEQGVVHIVGAGPGDPELLTLKALRVLQDA
DVIIHDRLVPEAVLERARRDAKRLYVGKARGEHSVPQDQIEALMIEEARAGHRVVRLKGG
DPFVFGRGGEELETMRAAGVPVFVVPGVTAALACAASAGIPLTHRDHAQAVTFVTAQAKP
GGVEADWTRLAGPNHTLAIYMGTDRAEETAARLIAAGRSPSTPVAIVENGSRPDERVLTG
HLDGLGAMVRGADLTGPALLFVGETAAFSAFAKTRTEAAA
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgcgtgtattcctcgcctccattccgcttgaggccgccaagatcgtgatcatcggcggt
ggcgagccggcgctggccaagctgcgactgtttctgaacacgcccgccgaggtggtgtgg
ttcgcgccagacggcgcgccccccaagatcgagacgccgttgacggcgccggaaccggtg
ctgcgtgcgccagaggctgacgaactcgccggcggacggctggtgttcatggcgctggac
gatgcggacgagctgacgcggctgggccatctcgcacgggcggcgggggctcaggtcaat
gtggtggacaagccgcatctgagcgatttccagaccccggccctgatcgaccgcgacgag
gtcgtgatcggcgtggcgaccggcggatcggcgcccattctggcgcgggatatccgcacg
gccatcgagggcgtgctgcccgccggactggcgaatgtggcgcggctggcgcgcgagttg
cgcgatacggtcaaggccagcgtgccggacttcatggcgcgccgtcgcttctgggagaag
gccttccgcggtccggccgcgacgctggcggcggaaggtcggacggccgaggcccggcgc
gagatgctgcgcctgttgaacacggccgcacccgaacagggtgtggttcatatcgtcggc
gccgggccgggcgatcccgaactgctgacgctgaaggcgctgcgggtgttgcaggacgcc
gacgtcatcatccacgaccgtcttgtgcccgaggcggtgctggagcgggcgcggcgcgac
gccaagcgtctgtatgtgggcaaggcacgcggcgagcactcggtgccgcaggatcagatc
gaggccctgatgatcgaggaggcccgcgccggtcatcgggtcgtgcgactgaagggcggc
gatcccttcgtcttcggtcgcggcggcgaggagctggagaccatgcgggcggccggtgtg
ccggtcttcgtggtgcccggtgtgacggcggccctggcctgcgcggcctcggcgggcatt
cccctaacccaccgcgaccacgctcaagcggtgaccttcgtgacggcccaggccaagccg
ggcggcgtcgaggccgactggacgcggttggcgggccccaaccacaccctggccatctat
atgggcacggaccgagccgaggagacggctgcgcgcctgattgcggcggggcgctcgccc
tcgacacccgtcgccattgtcgagaacggcagccgcccggacgagcgggttctgaccggg
catctggacgggttgggcgcgatggtgcgcggcgccgatctgacgggacccgccctgttg
ttcgtaggcgagacggccgccttctccgctttcgccaagacgcggacggaggcggcggcg
tga

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