Mycetohabitans rhizoxinica: RBRH_03260
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Entry
RBRH_03260 CDS
T01355
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC 6.3.2.10)
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
brh
Mycetohabitans rhizoxinica
Pathway
brh00300
Lysine biosynthesis
brh00550
Peptidoglycan biosynthesis
brh01100
Metabolic pathways
brh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
brh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RBRH_03260
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RBRH_03260
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RBRH_03260
Enzymes [BR:
brh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RBRH_03260
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CBW73835
UniProt:
E5ALG0
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All DBs
Position
294418..295848
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AA seq
476 aa
AA seq
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MTMLTLREAAALIDGATVLGDDTVAFDQVSTDSRSCGPASLFVALKGERFDAHDFLPDLA
RRGVAAVLVSRSPGDWRVPAIRVADTRAALGALAAGWRRRFALPLVAVTGSNGKTTVKEM
IASIFAAAVGHAQRLSTQGNLNNVIGMPLTLLQLAPQHRLAVVELGMNRPGETQQLARIA
GPTIALVNNAQREHQEFMATVEAVALEHASVIHALPPDGTAVFPADDPYAGIWRVAATDN
RIVDFALRRPGANSDAAVQGTTTDTGALRIETRAGALEVSLRAPGEHNARNALAATAAAL
AAGVGLDAIRRGLETFEPVNGRLQAKLAQAMPWAGATVIDDTYNANPDSMRAAIDVLTMR
QAPRVLVMGDMGEVGDNGPAFHREVGAYARERGLDALYALGDASRDACTAFGPHAHHFDS
AEALICALLRQDAVASERAAGATILVKGSRFMRMERVVQALTLPTATDAPARTGAH
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgacgatgttgacgctgcgcgaggcggctgcattgatcgacggtgccacggttttgggc
gacgatacggtcgctttcgatcaagtctcgaccgacagtcgcagttgcgggccggcaagc
ctgttcgtcgcgctcaagggcgagcgtttcgacgcgcacgatttcctgccggatctcgcg
cggcgcggcgtggctgctgtattggtgtcgcgcagccccggtgactggcgtgtgccggcg
atccgcgtggccgacacgcgggccgcgcttggcgcgctcgcggctggctggcgtcgcagg
tttgcgttgccgctggtcgcggtgaccggtagtaacggcaagaccacggtcaaggaaatg
atcgcgtcgatctttgccgccgccgtcggtcacgcgcagcggctctcgacgcagggcaac
ttaaacaacgtcatcggcatgccgctcacgttgttgcagctcgcgccacagcatcggctc
gcggtcgtcgagcttggcatgaaccgtcctggcgaaacgcaacagctagcccggattgcc
ggacccaccattgcgctggtgaacaatgcccagcgcgagcatcaggaatttatggcgaca
gtcgaggccgtggcgctggagcatgcgagtgtgatccatgcgctgccgccggacggcacg
gcggtgtttcccgccgacgatccgtatgctggcatctggcgggtggcggccaccgacaac
cggatcgtggacttcgcgctgcgccggcccggggccaatagcgatgcggcggtccagggc
acgaccacggacaccggcgcattgcggatcgagacgcgcgccggcgcacttgaggtatcg
ttgcgcgcgcccggcgagcacaatgcgcgcaatgcgctcgccgccaccgcggccgcgctt
gccgccggcgtcggactggacgcgatacggcgcgggctcgagaccttcgagccggtcaat
ggacggttgcaggccaagctcgcccaagcgatgccatgggccggcgcgacggtgatcgac
gatacctataatgccaatccggattcgatgcgcgcggcgatcgacgtattgaccatgcgt
caggcgccgcgcgtgttggtgatgggcgacatgggagaggttggcgacaacggccccgcg
tttcatcgcgaagtcggcgcctatgcgcgcgaacgcgggctcgatgcactgtacgcgctc
ggtgacgcgagtcgcgatgcgtgcaccgcgttcggcccgcatgcccatcatttcgattca
gccgaggcactcatttgcgcgctgctccgccaggacgccgtcgcatcggagcgcgccgcc
ggcgcgacgatcttggtcaagggttcgcgtttcatgcgcatggagcgcgtggtccaggct
ttgaccctccccactgcaaccgatgcgccggcccggaccggcgcgcattga
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