Brucella sp. BO3: GRI33_07545
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Entry
GRI33_07545 CDS
T10767
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
brub Brucella sp. BO3
Pathway
brub00290
Valine, leucine and isoleucine biosynthesis
brub00620
Pyruvate metabolism
brub01100
Metabolic pathways
brub01110
Biosynthesis of secondary metabolites
brub01210
2-Oxocarboxylic acid metabolism
brub01230
Biosynthesis of amino acids
Module
brub_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
brub00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
GRI33_07545 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GRI33_07545 (leuA)
Enzymes [BR:
brub01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
GRI33_07545 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
QMV26782
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Position
1:complement(1554970..1556697)
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AA seq
575 aa
AA seq
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MNQPVSTPKSVSQAVSARKGMPIAGTKYAPFPAPQLDDRTWPSKRIEKAPIWCSVDLRDG
NQALIDPMGHDRKERMFRLLIDMGFPEIEIGFPSASQTDFDFCRWAIEQGDVPDDVDLQV
LVQCRPELITRTFEALEGAKTPIIHFYNSTSELQRRVVFAKDVGGIKQIATDAAKMIMDM
AAKAGGGYRFQYSPESFTGTELDVALEICNAVIEIVKPTPDNKLIVNLPSTVEMNTPNVY
ADQIEWMCRNLDNRESLIISLHPHNDRGTGIAATELGLMAGADRVEGTLFGNGERTGNVD
VVTLALNMYTQGIDPGLDCTDINRMKEVYEYSNQLKIAERHPYVGELVYTAFSGSHQDAI
NKGMKARRSANSPVWEVPYLPIDPQDVGRSYEAIIRINSQSGKGGIAYILQADYGLNLPR
NLQVEFREIIQHITDEEGKELPSKRIYEEFQKLYVTQPDARIKFVDHHTYPDPEQKGRRI
LTAEITDNGVTTTIEGKGTGPIDGFVDALSKYLGVKMSVVDYSEHSLQQGSDASAISYVE
MVYPGGKLFGVGINDNIVSASLEAVVSAANRVIAK
NT seq
1728 nt
NT seq
+upstream
nt +downstream
nt
atgaaccagcctgtctccacgccaaagtccgtgtcccaagccgtatcggcgcgcaagggc
atgcctattgccggcaccaaatatgcgccgttccctgcgccgcagctcgatgaccgcacc
tggccttccaaacgtatcgaaaaggcgccgatctggtgttcggtcgatttgcgcgacggc
aaccaggctttgatcgaccccatggggcatgaccgcaaggagcgcatgttccgcctgctg
atcgatatgggcttcccggaaatcgagatcggtttcccgtccgcgtcgcagacggatttc
gacttctgccgctgggccattgaacagggcgatgttcctgacgacgtggatttgcaggtt
ctggtccagtgccgccctgaattgattacgcgcactttcgaggcgctggaaggtgcgaag
acgccgatcatccatttctacaattccaccagcgaattgcagcgccgcgtggtgtttgcc
aaggatgtcggcggcatcaagcagattgcgaccgatgcggccaagatgatcatggatatg
gctgccaaggctggcggggggtatcgcttccagtattcgccggaaagcttcaccggcacc
gaactggatgtggcgctggaaatctgcaatgcggtgatcgagatcgtgaagccgacgccg
gacaacaagctgatcgtcaacctgccttcgacggtggagatgaacacgcccaatgtctat
gccgaccagatcgaatggatgtgccgcaatctggacaatcgcgagagcctgattatctcg
ctgcatccgcataatgaccgtggcacgggcattgccgctaccgaactgggtctgatggca
ggcgctgatcgcgtggaaggcacgctgttcggcaatggcgagcgcacgggcaatgtggat
gtggtgacgctggcactcaacatgtacacgcagggcatcgaccccgggctggattgcacc
gacatcaaccggatgaaggaagtctacgaatattccaaccagttgaagatcgccgagcgc
catccttatgtgggcgagctggtctatacggctttctccggctcgcatcaggatgcgatc
aacaagggcatgaaggcgcgccgttcggccaattcgccggtgtgggaagttccttatctg
ccgatcgatccgcaggatgtaggccgctcctacgaggcgatcatccgcatcaattcgcaa
tcgggcaagggcggtatcgcctatatcctgcaagccgattacggcctgaacctgccgcgc
aacctgcaggtcgagttccgcgaaatcatccagcacattacggatgaagagggcaaggag
ctgccgtcgaagcgcatttacgaggagttccagaaactctatgtgacgcagcccgatgcc
cgcatcaagtttgtggatcaccacacctatcccgatcctgagcagaagggccgacgcatc
ctgacggctgagattaccgataacggtgtcaccacgactatcgagggcaagggcacggga
ccgatcgatggtttcgtggatgcgctgtcgaaatatcttggcgtgaaaatgtcggtggtc
gattattccgaacattcgctccagcagggttcggatgcttcggccatttcctatgtcgag
atggtttatcccggcggcaagctgtttggcgtcggcatcaacgataatatcgtcagcgcc
tcgcttgaagccgtggtgtcggcggcaaatcgtgtgattgcgaagtag
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