Brachybacterium sp. P6-10-X1: BH708_19140
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Entry
BH708_19140 CDS
T04713
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
brx
Brachybacterium sp. P6-10-X1
Pathway
brx00300
Lysine biosynthesis
brx00550
Peptidoglycan biosynthesis
brx01100
Metabolic pathways
brx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
brx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BH708_19140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BH708_19140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BH708_19140
Enzymes [BR:
brx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BH708_19140
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
APX34474
UniProt:
A0A1P8NJI7
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Position
4336437..4337909
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AA seq
490 aa
AA seq
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MLQITAREIADITGGRLVAGATGDELVTGTARIDSREVVGGDLFAAFPGEHVDGHGYAAA
AQQAGAALALVSRETAAPAVLVQDVRTALWDLAHAQLERARGENPELVVLAITGSAGKTG
TKDLLGTILRTAGETIAPAGSFNNELGLPLTVLRLTASTRFLVLEMGARGIGHVAQLTAI
ARPDISLVLNVGSAHLGEFGSVEGIARAKGELVEALTPAGRAVLNAEDRLVAAMAERSSA
PVLTWGFTTGEVRGQELTLDDDARVAFTLVVPEGLRTLGGTPITAGRFAVRPDLMGEHQA
ANVLAALAAALSAGVDPGAAAAALDGAKLASGQRMEALRAGGVLVINDAYNANPDSMRQA
LKTLAHLGRGRRTIAVLGEMLEMGPDTIALHDEIGRLAVRLNIGQLYVIGDGAAPIHHGA
SLEGSFGGESEYLDTADDAITVLKETLAPGDVVLLKSSRDAGLRQIARPLIDHLGRCETP
EGRADGGDDA
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgctgcagatcacggcacgggagatcgccgacatcaccggcggtcgcctggtggccgga
gccaccggggacgagctcgtcaccgggacggcccggatcgactcccgcgaggtcgtcggc
ggagacctcttcgccgccttccccggggagcacgtcgacgggcacgggtacgccgccgcc
gcgcagcaggccggggccgcgctggccctggtctcccgggagaccgccgccccggcggtg
ctggtccaggacgtccgcacggccctgtgggatctcgcccacgcccagctggagcgcgcc
cggggcgagaaccccgagctggtggtcctcgcgatcaccggcagcgccggcaagaccggc
accaaggacctgctcggcacgatcctgcgcacggccggcgagacgatcgccccggccggc
agcttcaacaacgagctcggtctgccgctgacggtgctgcgcctcaccgcgagcacccgc
ttcctggtcctcgagatgggcgcgcgcggcatcggccacgtcgcccagctgaccgccatc
gcccgccccgacatctccctggtcctcaacgtcggcagcgcccacctcggggagttcggc
agtgtcgagggaatcgcgcgcgccaagggcgagctggtcgaggcgctgacccctgcgggc
cgcgccgtcctgaacgccgaggaccgcctggtcgccgccatggccgagcgcagcagcgcc
cccgtcctcacatggggcttcaccaccggtgaggtgcgcggacaggagctcacgctggac
gacgacgcccgcgtcgccttcaccctcgtcgtccccgagggcctgcggaccctgggcggg
acgccgatcacggccggccgcttcgccgtccggcccgatctgatgggcgagcaccaggcc
gcgaacgtcctggccgccctggccgccgcgctgagcgccggcgtcgaccccggcgcggcc
gcggccgcgctcgacggggccaagctcgcctccggccagcggatggaggccctgcgcgcc
ggcggggtgctggtgatcaacgacgcctacaacgccaatcccgattcgatgcgccaggcg
ctgaagaccctcgcccacctcggacgcggtcgccgcaccatcgccgtgctcggcgagatg
ctggagatgggtccggacaccatcgctctgcacgacgagatcggccgtctcgcggtgcgg
ctgaacatcggccagctgtacgtgatcggcgacggcgcggcccctatccaccacggcgcc
agcctcgagggcagcttcggcggggagtccgagtacctcgacaccgcggacgacgcgatc
accgtgctgaaggagaccctggcgcccggcgacgtggtgctcctgaagtcctcccgggac
gccggcctccggcagatcgcccgccctctcatcgaccatctgggacgatgtgagacgccc
gagggacgggcggacggaggggacgacgcatga
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