Burkholderia semiarida: R0290_24630
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Entry
R0290_24630 CDS
T10421
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
bser Burkholderia semiarida
Pathway
bser00790
Folate biosynthesis
bser01100
Metabolic pathways
bser01240
Biosynthesis of cofactors
Module
bser_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
Enzymes [BR:
bser01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
R0290_24630 (folC)
6.3.2.17 tetrahydrofolate synthase
R0290_24630 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Phage_Mu_Gp27
Motif
Other DBs
NCBI-ProteinID:
XCV62219
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Position
2:1898179..1899489
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AA seq
436 aa
AA seq
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MSTFPTLDAWLSHLERAHPVGIDMGLTRIGQVKAALQLEFACPVITVGGTNGKGSTCAFL
ETILVRAGYKVGCHTSPHLLAFNERARVNGQNVTDDELLPHFEAVEAARTSLAEPVSLTY
FEFTTLAILHLFASRGLDAVILEVGLGGRLDAVNIIDTDCAIVTSIDIDHTEYLGDTREK
IAFEKAGIFRAGKPAICGDPAAPQTLVDHAEAIGADLWLVGRDFRYEAQAGAERQQWSYL
GRDKRYPALAYPALRGANQLINASAALAALEALRPVLPVSAQDIRLGLANVELPGRFQVL
PGKPAIVLDVAHNPHASAVLEQNLGNMGFFPYTYAVFGAMHDKDIDGVLQHLKGEIDHWC
VTDLPLPRAASAEQLEAALRKAGVEEGPDSSVTRYASPAEAFRDALKRASENDRIVVFGS
FHTVAGVLAYRKSQQH
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatttcccactctcgacgcgtggctttcgcatctcgaacgcgcgcacccggtc
ggcatcgacatgggcctgacccgcatcgggcaggtcaaggcggcgctgcagctcgaattc
gcgtgcccggtgatcaccgtcggcggcacgaacggcaagggctcgacctgcgcgttcctc
gagacgattctcgtgcgcgcgggttacaaggtcggctgccacacgtcgccgcacctgctc
gcattcaacgagcgcgcgcgcgtgaacgggcagaacgtgaccgacgacgaactgctgccg
cacttcgaggccgtcgaagccgcgcgcacgtcgctggccgagcccgtgtcgctcacgtat
ttcgaattcacgacgctcgcgatcctgcatctgttcgcctcgcgcgggctcgacgcggtg
atcctcgaagtcggcctcggcggccggctcgatgcggtgaacatcatcgacaccgattgc
gcgatcgtcacgagcatcgacatcgatcacaccgaataccttggcgacacgcgcgagaag
atcgcgttcgagaaggcggggatcttccgcgcgggcaagccggcgatctgcggcgatccg
gccgcgccgcagacgctcgtcgaccacgccgaagcgatcggcgccgacctgtggctcgtc
ggccgcgatttccgctacgaggcgcaggcaggggccgagcgccagcaatggagctacctc
ggccgcgacaagcgctatccggcgctcgcgtatccggcgctgcgcggcgcgaaccagctg
atcaacgcgtcggccgcgctcgccgcgctcgaggcgctgcgcccggtgctgccggtgtcc
gcgcaggacatccggctcgggctcgcgaacgtcgagctgccggggcgcttccaggtgctg
cccggcaagccggcgatcgtgctcgacgtcgcgcacaacccgcatgcgtcggccgtgctc
gagcagaacctcggcaacatgggtttcttcccgtacacgtacgcggtgttcggcgcgatg
cacgacaaggacatcgacggcgtgctgcagcacctgaagggcgagatcgaccactggtgc
gtgaccgacctgccgctgccgcgcgcagcctccgcggagcagctcgaagccgcgctgcgc
aaggccggcgtggaggaggggcccgattcgagcgtgacgcgttacgcgtcgcccgcggaa
gcgtttcgcgatgcactaaaaagagcatccgagaatgatagaatcgtggttttcggcagt
ttccatacggttgccggcgtgctggcctaccgtaaatcgcagcaacactga
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