KEGG   Betta splendens (Siamese fighting fish): 114846056
Entry
114846056         CDS       T08231                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
bspl  Betta splendens (Siamese fighting fish)
Pathway
bspl04010  MAPK signaling pathway
bspl04012  ErbB signaling pathway
bspl04020  Calcium signaling pathway
bspl04510  Focal adhesion
bspl04520  Adherens junction
bspl04530  Tight junction
Brite
KEGG Orthology (KO) [BR:bspl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114846056 (erbb2)
   04012 ErbB signaling pathway
    114846056 (erbb2)
   04020 Calcium signaling pathway
    114846056 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114846056 (erbb2)
   04520 Adherens junction
    114846056 (erbb2)
   04530 Tight junction
    114846056 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bspl01001]
    114846056 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bspl04147]
    114846056 (erbb2)
   04090 CD molecules [BR:bspl04090]
    114846056 (erbb2)
Enzymes [BR:bspl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     114846056 (erbb2)
Protein kinases [BR:bspl01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   114846056 (erbb2)
Exosome [BR:bspl04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   114846056 (erbb2)
CD molecules [BR:bspl04090]
 Proteins
  114846056 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 DUF5849 Tcell_CD4_C Haspin_kinase EphA2_TM Adeno_E3_CR2 Kinase-like
Other DBs
NCBI-GeneID: 114846056
NCBI-ProteinID: XP_028990640
UniProt: A0A6P7L9C4
LinkDB
Position
19:10220354..10233320
AA seq 1300 aa
MEAARSLLFVGAALLAVTGALAREVCLGTDMKLVLPSSLENHYETLRLLYAGCQVVHGNL
EITHLHGDLDLSFLQGIVEVQGYVLVAHVSVSLVPLDNLRIIRGSQLYNSSYALAVLGNT
RNGTGLRTLRLRSLTEVLLGGVDIWGNPQLCFPDPQSIVWKDTFDEQNTHFQRSRLQARA
PNCPSCSSACKSGCWGDTSQDCQILTRINCASGCQRCKGPLPNDCCHMQCAAGCTGPKDS
DCLACRHFNDSGVCKENCPPPTFYDTATFQTKPNPKKKFNFGATCVKTCPYNYLSMDVAC
TLVCPKDNQEVIITHPDGNETQKCEKCEKDCPKVCYGLGMDNGVMDNHGITMVTSDNVKQ
FNKCNKIFGSLAFLPQSFARDPATNQSSLTLEQLRAFKKLEEITGYLYIDAWPEEWSDLS
VFENLKVIRGRMLYKGVFSLAIQNLHIRSLGLRSLRSVSGGLVLLHNNPQLCYTSSLPWD
TILHPTQGPHRIVSRNQDPKVCEAEGFVCHPLCVEGCWGPGPGQCVSCKAFRRGTECVEQ
CDVYQGSTREYMEGFKCISCHAECQLLNGSASCHGPGADHCTACQNFQDGEFCVERCPSG
VKEEQQTVWKYSNATNHCLPCGTNCTLSCTVMDERGCPVDVRAGPGTTIVAAVTGVVLVL
ILVALLVFCVRRQRNLKRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLRV
LGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVCRL
LGICLTSTVQLVTQLMPYGCLLEYVRENKDHIGSQYLLNWCVQIAKGMNYLEEVRLVHRD
LAARNVLVKNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSDV
WSYGVTVWELMTFGAKPYDMIPARDIPDVLEGGERLPQPLICTIDVYMIMVKCWMIDPDS
RPKFKDLVSDFSAMARDPPRYVVIQNDEQMCLASPVDSQFYRMLMEEEGNDMRDLLDAEE
YLVPQPNVFPRAQGDGAQSNGPSRHQSYRSREHGLDVEPLFAGGPRSMYSSLSTLSRSQY
PTLPMGASASNGLRALYPALNRSPSSGDQSDSVFLDTNPDDPSLPPASPGRYSKDPTNPN
GSLDDLDTDGPMDFYQPHQLHHSLPRRSHGNIQVHALPEYVNQEIQNLRPGIPERPSTLP
RKGSRVDRRLPNGLNSGHSVENPGYLVPVSSRTPTSPAFDNPYYLDFMIKAMAAAGPAPG
DGPRLPERDGGMPRHVNGFVTSTAENPEYLGLVDTWSGHS
NT seq 3903 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagtttgctgtttgtcggggccgcgctgctcgcagtcacgggcgcg
ttggccagagaagtgtgtctggggacagacatgaagctggtcctgccctccagcctggaa
aaccactacgagaccctgaggctgctctacgccggctgccaggtcgtccacggcaacctg
gaaatcacacacctgcacggcgacctcgacctctccttcctgcagggcatcgtggaggtg
cagggctacgtgctcgtcgcccacgtgtcggtgagcctggtgccgctggacaacctgcgc
atcatccgcggcagccagctgtacaactccagctacgcgctggccgtgctgggcaacacc
cgcaacgggacggggctccggacgctccggctccgcagcctcaccgaggtgctcctgggc
ggcgtggatatttgggggaaccctcagctttgctttccagacccacagagcatcgtttgg
aaggacacgtttgacgagcagaacacccacttccagcggtcccgtctgcaggctcgggcg
cccaattgtccaagctgctcgtccgcgtgtaagagcggctgctggggagacacgtcgcag
gactgtcagatcttgacccggatcaactgtgcgtccggctgccagaggtgcaaaggcccg
ctgcccaacgactgctgccacatgcagtgtgccgccggctgcaccgggcccaaggactcg
gactgcttggcctgccgccacttcaacgacagcggcgtgtgcaaagagaactgccctccg
cccaccttctacgacaccgccaccttccagaccaaacccaacccgaagaagaagttcaac
ttcggagccacctgtgtcaagacgtgtccttataactatctgtctatggacgtggcctgt
acattggtgtgtcccaaagacaaccaggaagtcatcatcacgcaccctgatggaaacgag
acacagaaatgtgaaaagtgtgagaaggactgtcccaaagtgtgttacggtctgggcatg
gacaatggcgtcatggacaatcatggcatcaccatggtaacgtctgataacgtgaagcag
ttcaacaagtgtaataagatatttgggagcctggccttccttcctcagagctttgcaagg
gaccctgcgaccaaccaatccagcctgactctggagcagctcagggccttcaagaaactg
gaggagatcacaggctacctgtacatcgatgcttggccggaagagtggagcgacctgagt
gtgtttgagaacctgaaggtgatcagaggcaggatgctctacaagggcgtgttttccctt
gccatccaaaatctacacatccggtctctcgggctgcgctcgctacgcagcgtcagcgga
ggtttggtcctgctgcacaacaaccctcagctgtgctacaccagctcattgccttgggac
accatcctccaccccacccagggacctcatcgcatcgtcagcagaaaccaagaccccaaa
gtctgcgaggctgaggggttcgtctgtcacccgctgtgtgtggagggctgctggggtccg
ggccccggccagtgtgtgtcttgcaaggctttccgacgtggcacggagtgtgttgagcag
tgtgatgtttatcaggggtccacgcgtgaatacatggagggcttcaaatgcatttcatgt
catgcagagtgtcagcttctcaacggctcggcctcgtgtcacggcccgggcgcagaccat
tgtacagcgtgtcagaacttccaggacggcgagttctgcgtggaacgttgccccagcggc
gtcaaggaggagcagcagaccgtgtggaagtacagcaacgccacaaaccactgtctgccc
tgcggcaccaactgcacgctgtcctgcactgtgatggatgagcggggctgtcccgtggat
gtcagggcaggacccggtacgaccatcgtagctgccgtgaccggggtggttctggttcta
atcctggtggccctgctggtcttctgtgtgagaaggcagaggaacctaaagaggaaggag
accatgaggaggatcctgcaggagcacgagctggtggagcctctcacgcctagcggtgcg
tcgcccaatcaggcccagatgcggatcctgaaggagactgagctgaagaagctgagggtg
ctgggtgcaggagcctttggtactgtttacaagggcgtgtgggctcctgatggggagaat
gtgaaaatcccagtggccattaaggtgttacgagagaacacctccccgaaggccaataaa
gaaatccttgatgaggcgtacgtgatggcgggagtggccagcccttacgtctgtcgcctc
ctggggatctgtctgacctccacggtgcagctggtcacgcagctgatgccgtacggctgc
ctcctggaatacgtcagggagaacaaggatcacatcggctcccagtacctcctcaactgg
tgtgtccagattgccaagggcatgaattacctagaggaggttcggctcgtccacagagat
ctggctgctcgcaacgttctggtgaagaacccaaaccacgtaaagatcacagatttcggc
ctggcccgcctgctcgacatcgacgagactgagtatcatgcagacggagggaaggtgcca
attaaatggatggccctggagtcaattctgcacaggaagtttactcatcaaagtgatgtt
tggagctacggggtcacagtatgggagctgatgacgtttggtgctaaaccatatgacatg
atcccagcgagggacatcccagatgttttggaggggggagaacgccttccccagcccctc
atctgcaccatcgacgtctacatgatcatggtcaaatgttggatgattgatcctgacagc
agacccaagttcaaagatctggtcagtgacttcagcgcgatggccagagacccccctcgc
tacgtggtcatccagaacgatgagcagatgtgtctggccagcccagtggacagccagttc
tacaggatgcttatggaggaggagggcaacgatatgagggacctgctggatgctgaggag
tacctggtgccccagccaaacgtcttccccagggctcaaggagatggggctcagtccaac
gggccttccagacaccagtcatacagaagcagagaacatggcttagacgttgagccgttg
tttgctgggggtcctcggagcatgtactcctccctgagcacgctaagccgcagccagtac
cccacgctcccaatgggagccagcgcctccaacggcctgcgggctctgtacccggcgctg
aatcgcagcccctcatctggggaccagtctgactccgtgttcttggacacgaatccagac
gacccctcactcccgccagcgagccctgggcgctacagcaaagaccccaccaaccccaac
gggagcctggacgaccttgacaccgatgggcccatggacttctatcagcctcatcagctt
catcactccctgcctagacgcagtcatggcaatattcaagttcatgctttgccagagtat
gttaaccaagagattcagaatctcaggccggggatccctgagcgacccagcaccctgccc
cgtaaaggctccagagttgaccgacgcctccccaacggcttgaattctggtcatagcgtg
gagaacccaggatacctggtgcccgtgagctccaggacccccacctcgccagcttttgac
aacccatattacctggacttcatgatcaaagccatggctgcggctgggccggcgccgggt
gacggcccgaggctaccggagagggatggaggaatgcccagacatgtgaacgggttcgtg
acgtccaccgcggagaatccagagtatctgggactagtggacacctggagtggacatagt
tga

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