Betta splendens (Siamese fighting fish): 114854800 Help Entry 114854800         CDS       T08231                                  Symbol obscna Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism bspl  Betta splendens (Siamese fighting fish) Pathway bspl04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:bspl00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     114854800 (obscna)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bspl01001]     114854800 (obscna)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:bspl04131]     114854800 (obscna) Enzymes [BR:bspl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      114854800 (obscna) Protein kinases [BR:bspl01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    114854800 (obscna) Membrane trafficking [BR:bspl04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     114854800 (obscna) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_5 Izumo-Ig SOS1_NGEF_PH C1-set Ig_CD22 RhoGEF V-set_CD47 PH fn3 IQ APH Motif Other DBs NCBI-GeneID:  114854800 NCBI-ProteinID:  XP_055364127 UniProt:  A0A9W2XQY9 LinkDB All DBs Position 4:complement(7960290..7989379) Genome browser AA seq 6119 aa AA seqDB search MGDIKIGIVAAAKNRLQVVKGLEDVEVEECESFSLEVTLNLAYMEGVWSRDGTRLKSKPN CRISMHGRKHSLVLKRAALGDGGLYCFEVDGIQTSGRLSVRARNIHIVTHLEDVDTVERQ PVNFLCEVNQVDVDARWYRDDCRIRPGDNIKIRHQGKTHSLFFKSVKPEHAGEIRFTADR VSSYATLTVTELPVQIVRPLRVKIAMYHHRGLLECQVSRPNAQVKWYKNRKEVVPNKKHH LISQDVYRQLVIEDVCSSDEDTYTCDAGDDNTSCQLLVEEQAISIVRGMSSVEVTEPEPA LFQVETSLKSGRPPKWTLNGDVLEHCAAVNMSRDGTVHSLRFSATESSMSGPVLFVAGKS RSTAQLTVKERPLQVVHHLEDTEAKESSSVTLSCQFAPSPRAVRWFKGRTALKTSNKYSM KREGTRAQLTIHGLTGVDAGQYRCTAGGAESSAHVRVEMRLLKLVKHLEPVEIEEDGIAS FSCELNYVVANVEWLLNNVRLYSNAINRIQHMGTMHSLTLKKLRPQQSRVTFKAGLLSQT ASLKVKERPAVFLRSLEDVVGEEQGEICLQCEVSKETVAPVWRKDNTVLAADDKHDILQF GKSMVLIVRSLSKDDAGEYTCDLGTSQSKAKVTVHDLHVSIVHRLKTTTVLEGEGCTFEC VLSHLVDDQPSWTINGQVVISNSRIQVISNGCKYKLSIRNALLTDAGDLVFTVKDLSCRT MLFVKEKPVHIFRTLLSVKAVPGEDAELSCEITKPEVTIRWLKNGQLIRQSPKYEMSVEK NSARLLIKNTTIRDSGEYCCEAEGIATRAKLDVRELQHTFARDLRETYAEEKGKVTLECE TRRPARRVTWLRGMVELRSSRKHIIRQKGVVLSLTITCLEKSDSDIYICDVGTMQSRAQL TVQGCKVLILQELEDVECLEGDTVTFRCQICPSDYVGVRWYLDETLLYTNELNEIQAVPG GFHMLTFKQLARKDTGTISFAAGGKRSYASLLVRERRPTIVRALEDCEAVEGGALVLSCV ASKPCHILWYKDGCLMWNSSRYFSSRSGCEARLTIREVCSGDAGVYECSAGAVTTRATVT VKAIPAEFTQPLVAAEAREGDSVTLTCEYSLPGVQFHWRKGVESLRAGDKYVMKQRKTIN SLTIKALKLEDSGEYTCQCRDHRTTASLKVDAVPIKFIQQLKNIQAEEGTNVMLRCELSK PGIAVEWRKGQEPLHNGVKHQIRKRETTLELLIWRSAPEDSGIYSCVCANVMTSATVKIN ALPVTFKQKLRNVAIEEGNTATLRCELSKPGLVVEWRKRASGVIRNGEKYHIRQRDMLIE LRICDVKLEDSDVYTCTCGNIETAATLTVNAIPVTFKQKLKNLQVEEGHNITLCCEVSKA GVPVEWRLGGDLLESGEKYQMKQRDSAVELTIKDAAPEDSGVYSCVCRQQRTKATVKVIA VPATFKVSLRSQEAEEGSSITLRCELSKKGAPVQWHREGQLLSEEISQRRYEMKVEGRTA LMTIHSLRPDDAGKYSCLTGDEKTTAEIRVKPLPVTFKREIQRLVVKEGASGVFCCELSK PGALVEWMKGRVAIRPGGKYEMKQEGRLTKLVINHTEESDGGKYTCKTKDSQCTAELIVQ GLPPSFRLPLVSQEATEGNSVVLHCELNKAAPSVEWRRGAELLRSGDKYQMRKKDLQVEM RITDLNLDDAGDYACTCGEQRTTAKLTVKERPIKFLQDLKNIQVQEGNGVLLSCTLSKHD VPVQWMKGDNVLTDGEKYQMKQSGSTLELLIRKSQPEDSGTYSCVCEDLKTTATIIITPI PVTFKQKLKNQEAVEEGSVTLRCELSKPGVPVEWRKDAQLLKAGDKYEMKQESRVAEMLI RNLTLRDAGEYCCSVGTVETSSDVKVRALPVTFKQVVENLEVKEGDSGVFCCELSKPQAP VEWRKGRVILKPGYKYEMKQEGPLTKLIINSVEESDAGKYTCQTKDSQSTAELIVKAPPV TFKTKLRSQQVEEENSITLSCELSKPGLPVEWRRGEELLKNNFKYQIRNRNSIMELTIKN AQLEDSGLYSCNYGDVKTTADVTITPIPLSFKTGLKNQEAPEGGNVTLRCELSRAGVPVQ WWKAEDQLSHGGRYQLIQNGKTAEMHIKNIQPEDVGEYSCVFGEQKTTAEVNVRAAASVY FEKELKNQVVMEGKSVVLSCEVSSANVPVTWRKDSVVLEEGARHILKKNGPTHSLEINKL LLQDAGEYCCISRGKRTTARLTVRERVRIVTQLRDVTVTAGADAVFVCELSHADVTEGVW WLGPSPLQKNEMNQMTCQGRQHRLVLTMTTPEETGTVAFVIGEERTSARLLVVPRPKVLI EKKPEDVVIMEGAKATLSCTISDVTSEVTWQRNYITLLSDDKYELRKEGKVNLLLIHDVD PLDSGIYTCDTGDMQSSAKLTVTELPPFFQEELQSVEEDEGRSACLYCELSKLGVPVQWK KNRLPLKASRKYEMRQDGCFLQLHIRDLKLEDSGSYSCQAGNAETTATVRVKELPPFFTK RLRNVDAEEGGAASLCCELSKPGMSVQWKKNKLPLRNCAKYEIKQDGCLLQLHIKELRPE DSGSYTCQAGNAETAATVAVKELLPFFPVPLQNVKAEEGGSATLCCEMSKPQGSVQWKKN KQPLRANEKYDMKQDGCLLQLHIRQLTLEDGGSYACHIGSVETTATVTVKELPSFFKQEL QGMEAEEGGGVALCCELSKPGARVQWKKNQMPLRAGRKYEMKQDGCSLQLYIKELKPEDG GIYTCLAGSAETTATVVVKELAPFFSKGLHSVEAEEGAAASLTCELSQPAVSVQWKKNKL PLRANRKYEMKQEGCLLQLHIKELKPEDGGSYTCQAGGAETTATVRVKEFPLFFKKDLEN VKTKEGGALSLHCEVSKPSVTVQWKKNSLPLRANRKYEMKQDGCSLQLHIQELKPEDSGT YSCRAGSVETTATVTVEALQPAAPEAETITTLTQTPAVDGERNHHPVPPEPKKRTHRKAS ITNAQEEDSSFGLKRSTMLSENNEVQRGSHSVKTEEKDFSDLQNINQLVKQDSEVHQANN EPVRIVKQEQRPPGPLEEFNKVKQPERKPGETVGKHIQQSIICVEMEPEIEQISRESRRP SEKTGEAEKKLTGVLWRKHEDETQPVKPLNGKEPVDDAKHIENTDVIDKTEKEPFRPRAR SKEGSAGKQTITRHVKEEREEVISQSKPTEDTYKPREDVKQVSKEADREKTQTDDMGSIN DLGKQSAEKLEKSLGQEVKSVVPKAPVRTKSKTKGGVEKQLSRDTGTDQDEQELTPVMVK SVTGLPIKQTLIPVKREAEENTVTPDIKIRKREQQREREQQKEGEQQREREQQREREQQK EGEQQREREQQTDGEQQRGEQQREGEQQKEGVLHRERKQQREREQQREKEQQREREQQKE GEQQREREQQRDREQQGEGEQQKEGVLHRERKQQREREQQREKEQQRKGEQQKEGVQQRE GEQQRERQQQREREQQKEGEQQRESEQQREREQQKEGEQQREREQQRDGEQQREGEHQKE GEQQKESEQQREREQQRESEQQREGEHQRDREQPRARLQKLKKATQKDINKPIKQSVKPM RKEPEMAVNLEAEAKMVDEELQAAVTEDVLLLSGDETFSEALSEMPLKQPDIHPVHSSGQ GSTQAPVPPLQTQPSNDASPDTEVSTDDQPQMQEAAVKIQAAFKGYKTRKGMRPLFKEVF KNQSADLHGTVTLVCVVEGKASSVRWLRNGQQISKDPRCRTEAAEDGVCSLVIKNLTTND TGTYTCEVVNKFGVTSYNGNLTVVPPQQPQQPAPAAQKPVHPPLAAIAPLQPAAAKPAPQ LESQAQAQIPAPVEDAANYVESVSISLWEAYNLTEQVSAEGSRERRGSSLIAASSVSSPS DHETAPDVMENVETSAAVPREVPKPVEPPILDEKEDMAVPQCTKKLLKVKGAHEGRTPSP KHRAHTPLTSTVSGSESEGEGDRRETFDMYVARADCSPTGGNKEHFVVKEGQFVEVLDCV HPDRWLVRTKPTKTNPARQGWLCPAYLEKKRKETFPHLRAPHEDLDGIGSTGEEYRRALS QLVQGLIDGEEEFVKEMKTFTSHQLNYLDSSRHVPINILNQKEIIFRNIKDIVFLHERSI LPGLRACATDDDVAAHLLKHSEDFETYLHYMVGQAQAEACVADKAARQYFNELTECSKPD AVVMDVLTFLRRPVERIQTYQALLKEFIKNKAKSGQNCCLLEDAFSVVSCLPWRSDNLHQ VSLIENYPAPLTALGEPVRQGMFTVWEESSDDKTASRGHQRQVFLFRESVVLCKLKRDTS INSDTCTFKNKMKLNDVEIKESVCGDDKSWGLWHEHRGSLRRYILQSRSALVKLSWLKDL KDLQQRFSLPSNSPPLFEALLSDTTTKIGHTVKLTCRVTGLPAPVVTWFKDGLPLEDDPR HIIAADRSGTCSLILDSLTAEDSGQYMCYAASSLGSAGTLAKVVVQAPPRFVRRLESACL IEGDDIQFTCSTLTTPLPQIRWLKAGRALTDPQKYAILNDARSGILCLTVIGATKADIGQ YECELRNEFGCVKCKAGLCPAYVPPIESETGQPQNLPPKDADSEGWSTAFVKKWLQTDFS PTSIAKMLFPPGHPEQAECGLEEDAPASLSTDQTAKQPPCYIEEEEEEIFIPEPMQEITD APPSIQVPTEDLYVEPGQSATFTAIITGRPTPRVEWYKDGEELADNENVEIAQHGARCSL TIFSPEGEDSGTYTCFAHNDSGHASCQSQLTVEEGPLEFQEREVELGKRRKLFSVYDVHE EMGRGTFGVVKRVVHRRTGEVFAAKFLPLRGSTRTRAFQERDLLSRLAHPRVACLLDFFC TRRTLVLITEICCSHGLLDHLLLQGSVLEKEVQSYIQQILEGVGHIHSMNILHLDIKPEN ILMVYPPRDEIKICDFGFCQEIDTSRHQYSVFGTPEFIAPEIVHQEPVTVATDIWAVGVM TYLCLTCRCPFVGETDRATLLRVGEGTLNWEAPDVTNRSPEAQRFLHAVLQLDPEKRPSA FECLSHEWFQDEQSGEDTDEINTKSLKAFISKRKWQRSLTCIGSVLTLRPIPELLDAPLR DTAVTVTREPQDHSSSSVSSGSSSEYDEADSWDFFQHCSPTEEEEETEEDYDPLMERAQI PDHFSKLQPDAEEEEVTLGEEADEDVLGRRSVLERSVSRQSVASSDVSLQTPQRERRFSK DSTPSLCLSDGDEGSGSDGSRIPRGSVIRSTFYSTSHQLSPMSARHMSLRDKFQAKKQER GRKPLRRSFSGRLNEPLIEYVEDETETTRSHRRGSIQPTVHKFSSFDSAGDLTHANVPPH RRSRSLDESSRRSPDSTPGEEGGSQRRREDSTDDERTSPAILSPSRPPRRRGSVAAVQRP LIFGATSGPSSFCAGDRMNAKLDQEQNEGDTFTGSQGSLAGSSILEHGGSESSSRLGSYE ELSHGRLRGRCRSGDSDGYDDQGEPLISSSPCSFQEVKLRSSFPQAPPRNRTRSNPNLST GSRGYSMTPQPPSSSPSLSSLQAPERPPRAKDKNLSHGLQRHASAPALEVQPPTGKSPKL GFLKIFRRQSWTEHSYSKLENTGLGPTLGEIMKPDTPTMSLRKKMRASASSLTKLFSRSS SKEDVSKGPIVKGSGPVPPERTRSTSLESPKKKTPKLLQSFKIPAFKRTKDPPARPSKAD VLRLDGGGVLLVWKPVQCNDAVTYCVQYCTDGGEWTMLSEEVTDSCFVAKDLPRGASYVF RVGCVTRTGAGPFSDASAPVVVATHTEETHIPLIQTEELGSKVTGSEEQTAHRSYSFLSE IGRGRFSIINLCRDAETSQVFAAKITPYQAEQRQLVLREYQLLKRLHHPHLLQLHAAFIT SCYMVLLEELCPGKELLHSLAARDLYSETHVAELLAQILKAVDYLHSRRVIHLDLKSDNM LVDDCNHLKIVDFGSAQPFTPGQPLAVEHIHGLTESKVYIILPKAPEILEGQGVGPETDV WAVGVLSFIMLSADSPFHAELSWEQDRNIKKGKIQFGRCYPGLSEGALSFMKSSLNNKSW GRPTAAECLQNPWLRAYRTPHRARHSKVCFSTDKLKAYLQQKEEKREQVCTKLQCPFVQ NT seq 18360 nt NT seq  +upstreamnt  +downstreamnt atgggggacatcaaaataggaatagtagctgctgcaaagaaccggttgcaggtggtgaag ggattggaggatgtggaggtggaggagtgtgagagcttctccctggaagtgactcttaac ctggcctacatggagggtgtgtggagcagggatggcacgcgcctcaagtccaagcccaac tgtcggatcagcatgcacggcaggaagcactccctcgtgttgaagagggcagctttagga gatgggggcttgtactgctttgaggtcgatggcattcagacctcgggtcgactcagtgtc agagcgaggaacatccacatagtgacacacttggaggatgtcgacacagtggagcgtcaa cccgttaacttcctgtgtgaggtcaaccaggtggatgtggatgctcgatggtacagagac gactgcagaatccgccctggcgacaacatcaaaatcaggcaccagggtaaaactcatagt ctcttctttaagtcggtcaaaccagagcatgcaggagagatcaggttcaccgcggaccgc gtgtcatcctatgcaacactcacagtaacggagcttccagtccaaatagtgcgtcctctg agggttaagatagccatgtaccaccaccggggtctgctggagtgccaggtgtcacgacct aacgctcaggtcaagtggtacaaaaacaggaaggaggtcgttcccaataagaagcaccat ctgatcagccaagacgtctacaggcagctggttatcgaagacgtgtgttcctcagatgag gacacctacacctgtgatgcaggagatgacaatacctcctgccagcttctggtggaggag caggctatcagcatagtgcgggggatgagctcggtggaggtgacggagccggagccggcg ctgttccaggtggagaccagcttgaagtcggggaggcctccgaagtggaccctgaacggc gacgtgctggagcactgtgcagcggtgaacatgagcagggacggaaccgtccacagcctc cgcttcagcgccacagagagctccatgtcgggacccgtgctctttgtggctgggaagagc cgcagcaccgctcagctcactgtgaaagagcggcctctgcaggtcgtccaccacttggag gacacggaggccaaggagagcagctctgtgacgctgagctgccagttcgccccttcgccg agggcggtgcgctggttcaagggccgcacggcgttgaagacctccaataagtacagcatg aagagagagggcacacgagcgcagctgaccatccacggcctgacgggcgtggatgcgggg cagtaccgctgcacagcagggggcgcggagagcagcgcacacgtcagagtggaaatgcgg ttgctcaagttggtcaaacacctcgagcccgtggagattgaggaggacggcatcgccagt ttctcgtgtgaactcaactacgtggtcgccaacgtagaatggctcctcaacaacgtccgc ctctactccaacgccatcaacaggatccagcacatgggcaccatgcacagcctcaccctc aagaagctgcggccgcagcagagcagggtcaccttcaaggcgggcctcctctcccagacg gccagcttaaaggtcaaagagcgcccagcagtgttcctgagatctctggaggatgttgtg ggagaagagcaaggggagatctgcctgcagtgtgaggtttccaaagagacagtggcgcct gtgtggagaaaggataacacggtcctggctgctgatgacaaacatgacatactccagttt gggaagtccatggtgctgattgttcgttcactgagcaaagatgatgctggagagtacacg tgtgacctgggcaccagccagagcaaagctaaagtcacagtacatgacctgcatgtgagt attgtccaccgtttgaagaccaccactgtcctggagggagaaggctgcacctttgaatgc gtcctctcccaccttgtcgacgaccaaccgtcttggacaatcaatggccaggtcgtgatc tccaacagccgcatccaggttatcagcaatggttgcaagtataagttgtccatcaggaat gctttactgaccgacgctggagatctggtcttcacagttaaagaccttagctgtaggacc atgctctttgttaaagagaagccggtgcacattttcaggaccttgctcagcgtcaaggcg gtgccaggcgaggatgcagaactgagctgtgaaatcaccaagccagaagtcaccatccgc tggctgaagaacggccagctgatcaggcagagccctaagtatgagatgagcgtggagaag aactcggcgcggctgctcatcaaaaacacgaccatcagagactctggcgagtactgctgc gaggccgagggcatcgccacccgggccaagcttgacgtccgagaactgcagcacacgttt gcaagagatttgagggaaacgtatgcggaggaaaagggtaaagtgacccttgagtgcgag accaggcggccggccaggcgcgtgacctggctcaggggcatggtggagctgaggtccagt aggaagcacatcatccggcagaagggagtggtgctgtcgctgaccatcacctgcctggag aaatcagacagcgatatttacatatgtgacgtgggcactatgcagagccgggctcagctg accgtgcagggttgtaaggttctgatcctacaggaactggaggatgttgagtgtctcgaa ggcgacaccgtcacgttcaggtgtcagatatgtcccagcgactacgtgggcgttcggtgg tacctggacgagaccctgctctacaccaacgagctgaatgagatccaggcggtgccgggc ggcttccacatgctcacgttcaagcagctcgcccgcaaagacaccggcaccatctcgttc gcagcgggcggcaagcggtcgtacgcctcacttttggtcagagagcgacgccccaccatc gtcagagcgctggaggactgtgaggccgtggaaggcggcgcgttggttctgtcatgcgtg gcctccaaaccttgtcacatcttgtggtacaaagacggctgcctgatgtggaactcctcc aggtactttagcagtcgttccggctgtgaggctcggctgacgatccgggaggtgtgcagc ggtgatgccggggtgtacgagtgcagcgctggagccgtcaccactagggccaccgtcact gtcaaagccatcccagcagagttcacccagcctctcgtggccgctgaggccagagaggga gattcggtgactctaacctgtgagtactctctgcccggggtccagttccactggaggaag ggtgtggagagtcttagggctggagacaaatatgtgatgaaacagaggaagacgatcaac tctctgaccatcaaagccctgaagcttgaagactctggagaatatacctgtcagtgccgg gatcacagaacgacagcaagcctcaaagtggatgctgttcccattaagttcatacaacaa ctgaagaacatacaagcagaagagggcactaatgtcatgcttcgctgtgagctgtccaaa cctggaatagcggtagagtggagaaaggggcaggaaccattacacaatggagtcaaacac cagatacggaaacgagagaccacgctggagctgctcatatggaggtctgcgcccgaggac agtgggatctacagctgtgtttgtgctaatgtcatgacatcagccactgtcaaaatcaat gcgcttccagtgaccttcaagcagaagctgaggaacgtggcgatcgaggagggaaacaca gcgactttacgctgtgagctgtctaaacctggcctcgttgtggagtggaggaagagagca agcggcgtcatcaggaacggagagaaatatcacatacggcagcgagacatgctgattgag ctgaggatctgcgatgtgaaactggaggacagcgatgtttacacgtgcacctgtggaaac atagagacagctgcaactctgactgtcaacgcaattcctgtcaccttcaaacaaaagctg aagaatctccaggtggaggaaggacacaacatcacgctgtgctgcgaggtttctaaagcc ggcgttccagtggagtggcggctcggaggagatctgctagagagtggagagaagtaccag atgaaacagcgggactcggccgtggagctgaccatcaaagacgccgcgcccgaggacagc ggggtttactcctgcgtgtgtcgacaacagagaaccaaggccactgtcaaagtcatcgcg gtccctgccacatttaaagtgagcctgaggagccaggaggcggaggaagggagcagcatc acgttacgctgtgagctgtcaaagaagggagcccccgtgcagtggcaccgggagggacag ctgctctccgaggagatatcacagcgaaggtacgagatgaaggtggagggaaggacagct ctgatgaccattcacagcctccgaccagacgatgcaggaaagtacagctgcctcacagga gatgagaaaaccacagctgaaatccgagtgaaaccacttcctgttacattcaaacgggag atccagcgcctggtggtgaaggaaggggccagcggcgtcttctgctgtgagctctccaaa cccggagccttggtggaatggatgaaaggcagagtcgccataaggcccggagggaaatac gagatgaagcaggaggggcgtctcaccaagctggttattaatcacacggaggagagtgat ggcggcaaatacacctgtaaaactaaagacagccagtgcacagccgagctcatcgtccaa ggtctgccgccgagcttccggctgccactcgtcagccaggaagcgaccgaaggaaacagt gtggttctgcactgtgagctcaataaagccgccccgtcggtggagtggaggagaggagcg gagctgctgaggagcggggacaagtatcagatgaggaagaaggacctgcaggtggagatg aggattacagacctcaaccttgacgacgctggagattatgcttgtacatgcggggaacag aggacgacagcgaagctcacggtgaaagagcgacccattaaatttcttcaagatctgaag aacatccaggtgcaggaggggaacggggtgctactgagctgcacgctctccaaacacgat gtcccggtgcagtggatgaagggagataacgtgttgaccgacggagagaagtaccagatg aagcagagcggctccacgctggagctcctcatccgaaagagccagcctgaggacagcggc acctacagctgcgtttgtgaagacttgaaaacgaccgccaccatcatcatcactcccatc ccagtgaccttcaagcagaaactgaagaaccaagaagccgttgaggagggcagcgtgacg ctgcggtgtgagctttctaagccaggggttcctgtggagtggaggaaagacgctcaactc ttgaaggcgggagacaaatatgagatgaagcaggagagcagagtggctgagatgctgatt agaaacctgactctcagagatgcgggcgagtactgctgttctgtcggcactgtggagaca tcatctgacgtcaaagtaagagctctgcctgtaacgtttaagcaagtggtggaaaacctg gaggtgaaggagggagacagtggcgtgttctgctgtgagctgtccaagcctcaggctcca gtggagtggaggaaaggaagagtcatcctgaaacctggttacaaatacgagatgaagcag gagggacctctcactaaactgatcattaacagcgtagaggagagtgacgctgggaaatac acctgccagactaaagacagccaatcgactgcagagctcattgtcaaagctcctccagtc acatttaagacaaagctaaggagccagcaggtggaggaggagaacagcataacgctgagc tgtgagctgtccaagcctggccttcccgttgaatggaggagaggggaagagctgctgaag aacaattttaaataccagataaggaatcgaaacagcatcatggagctaaccatcaaaaat gcacaactggaggacagtgggctctacagctgtaactatggtgacgttaagaccacagcc gacgtcaccattacacctattccactcagcttcaaaacgggcctgaagaaccaggaggcg cccgagggaggcaacgtgactctccgctgtgaactgtccagggccggcgtgcccgtgcag tggtggaaggctgaagaccagctctctcacggaggacggtaccagctgatacagaacggg aagacggctgagatgcacatcaaaaacatccagcctgaggacgttggggagtacagctgt gtctttggagaacagaagacaacggctgaagtaaacgtgagagcggcagcgtctgtgtat tttgagaaagaactcaagaaccaagtggtgatggaggggaagtcagtagtgctctcttgt gaggtctccagtgctaatgttcccgtcacctggaggaaggacagcgttgtgctggaagaa ggagcccggcacattttaaagaagaacggccccacacactctttggagatcaataaactg cttctgcaggatgctggggagtactgctgcatcagcagaggcaagaggactactgccagg ctgactgtgagggagcgtgtgcggattgtgacacagctgcgggacgtcactgtgacagct ggagcggacgcagtgtttgtgtgtgagctgagccacgcagacgtgaccgagggcgtctgg tggctgggtcccagtcctctgcagaagaacgagatgaaccagatgacttgccagggccgc cagcaccgactggtcctcaccatgacaacgcccgaggagacgggcaccgtggcgtttgtg atcggggaggagaggacgtccgcacgtctgttagtagttccaaggcccaaagttttaatc gagaagaagccagaagatgttgtgatcatggaaggagcgaaggccaccttatcctgcaca atctctgacgttacgtctgaagttacctggcagcgcaactacattactctgctcagtgat gataaatatgagctgcgtaaggaggggaaagtcaacctgctgctcatccatgatgtggat cccctggacagtggaatatacacatgtgatacaggagatatgcaaagcagtgccaaactc actgtaacagagctcccgccgttcttccaggaggagttacagagcgtagaagaagacgag gggcgctcggcctgtctgtactgtgagctgtctaaacttggagtgccagttcagtggaag aagaacaggctgccactgaaagccagcaggaagtatgagatgaggcaagatggctgcttc ctccagctccacatcagggatctgaaacttgaggacagcggcagctactcatgtcaggcg ggaaatgcagagaccactgcaactgtgagagtgaaagagctccctccgttttttacaaaa aggttaagaaatgtcgacgctgaagagggaggtgcagcctccctgtgctgcgagctgtcc aagcccggaatgtcggtgcagtggaagaagaacaagctgcctctgagaaactgcgcaaag tacgagatcaaacaagatggctgcctcctccagctccacataaaggagctcagacccgag gacagcggcagttacacgtgtcaggcaggaaatgccgagactgctgcaactgtagcagtg aaagagctcctgccattttttccagtgcctttgcagaatgtgaaggctgaagagggaggt tcagcaacgctgtgctgtgagatgtcaaagcctcagggatccgttcagtggaagaagaac aagcagccactgagagcaaatgaaaaatatgatatgaaacaagatggctgtctcctccag ctgcacatcaggcagctcacacttgaggatggtggcagctacgcgtgtcacataggaagt gtcgagaccaccgccactgtgacagtgaaagaactgccctcatttttcaagcaagaattg caaggtatggaggctgaggagggaggtggcgtcgctctgtgctgcgagctgagtaaacct ggcgcacgagtgcaatggaagaagaaccaaatgcccctaagagccggcaggaagtatgag atgaaacaagatggctgttcccttcagctctacatcaaggagctcaaacctgaggacggc ggcatttacacttgtctggcaggaagtgcagagaccacggcgactgtggtagtgaaagag ctggctccgttcttcagcaaaggattacacagtgtggaggctgaggagggagcggcagcc tccctgacctgtgagctgtctcagcctgcagtgtctgtgcagtggaagaaaaacaagctg ccactgagagcaaacagaaagtatgagatgaagcaggagggttgcctcctccagctccac atcaaggagctcaaacctgaggacggcggcagctacacgtgtcaggcaggaggtgcagag accactgcaactgtgagagtgaaagagttccctctattctttaagaaagacttggaaaat gtaaagactaaggagggaggtgcactctccttgcactgcgaggtatctaagcccagcgtg acagtacaatggaagaagaacagtctgcccctgagagcaaacaggaagtacgagatgaag caggacggctgttcactgcagctccacattcaggagctcaaacccgaggacagtggcacc tactcctgtcgcgcaggaagtgtagagaccactgcaactgtgacagtggaagcactacaa ccagctgcaccagaggcagagactatcacaacattaactcaaacgcctgctgtagacggt gagaggaatcaccaccctgttcctccagagccaaagaagaggactcatagaaaagcttct attacaaatgcacaggaagaggactcctcttttggccttaaacgctccacgatgttgagt gaaaacaatgaagttcaacgtggcagccattctgtaaagactgaggagaaagacttcagt gacctgcagaacataaaccaacttgtgaagcaggacagtgaggtacaccaagcaaataat gagcccgtgagaatagtgaagcaggaacagagaccaccgggacctttggaagagtttaac aaagtaaaacagccagagaggaagccaggtgaaactgttggaaaacatattcaacagtcc ataatatgtgtggaaatggaacccgaaatagaacagatctcaagggaatcaagaagacct tcagaaaaaacaggtgaagctgagaagaagctcacaggcgtcctttggaggaaacatgaa gatgaaacacaacctgtgaaacccctaaatggaaaagaacctgtggatgatgccaaacac atagaaaacacagatgttatagacaaaacagagaaggagcctttcagaccaagagcaaga tctaaagaggggtcagcaggaaagcaaacaataacaagacatgttaaagaggaaagagag gaagtgatttcccaatcaaagcctacagaagacacctataagccaagagaggatgtgaaa caagtgtccaaggaggcagacagagaaaagacacaaacagatgacatgggttctattaat gacctgggtaaacagtcagcagaaaaactagaaaagtctttaggacaggaggtaaaatct gtcgttccaaaagcgccagtgaggacaaagagtaaaaccaagggtggagtagaaaaacag ttatcaagggacactgggaccgatcaagatgaacaagaactgacaccagtcatggtcaaa tctgtgaccggtctgcccataaaacagacactgatacctgtgaaaagagaagccgaggag aacacagttacaccagacatcaaaatcagaaagagagaacagcagagagagagggaacaa cagaaggagggagaacagcaaagagagagagaacagcagagagagagggaacaacagaaa gagggagaacagcaaagagagagagaacagcagacagatggtgaacaacagagaggagaa cagcagagagaaggagaacaacagaaagagggagtactgcacagagagagaaaacagcag agagaaagagaacagcaaagagagaaagaacagcagagagagagggaacaacagaaagag ggagaacagcaaagagagagggaacagcagagagatagagaacagcaaggagagggagaa caacagaaagagggagtactgcacagagagagaaaacagcagagagaaagagaacagcaa agagagaaagaacagcagagaaagggagaacaacagaaagagggagtacagcagagagag ggagaacaacaaagagagagacaacagcagagagagagggaacaacagaaagagggagaa cagcaaagagagagtgaacagcagagagagagggaacaacagaaagagggagaacagcaa agagagagagaacagcagagagatggagaacaacagagagagggagaacatcagaaagag ggagaacaacagaaagagagtgaacagcagagagagagggaacagcagagagaaagcgaa cagcagagagagggagaacatcagagagatagagaacagccgagagcgagactacagaaa ttaaagaaagcaacccagaaagacattaacaagcctatcaagcagtcagtaaaacctatg agaaaagaacctgaaatggctgtgaacctggaagctgaagcaaagatggtagacgaagag ctgcaggcagccgtaacagaggacgttctccttctgtcaggagatgaaaccttttctgag gctttaagtgaaatgccattgaagcagcctgacatccacccagttcactcctcaggtcag gggtcaacccaagcccctgtccctcccctgcagacccaaccctccaatgacgcatcacct gacactgaagtcagcactgacgaccaaccacaaatgcaagaggctgcagtcaagatacag gctgccttcaaaggctacaagacccgcaaaggcatgcgaccgctctttaaggaggtgttc aagaaccagagtgcagatctgcatggtacagtcactctagtttgtgttgtcgaaggaaaa gccagctcagtgcggtggctgagaaacggccaacaaatcagcaaggacccgcgatgtcgc actgaggctgcagaggacggggtctgcagccttgtcataaagaacctgaccactaatgac acggggacttacacgtgtgaggtagtgaacaagtttggcgtcacctcctacaatgggaac ttaacagtggtgccgcctcagcagcctcagcagcctgctccagcagcccagaagcctgtg cacccgccgctcgcggccatagcccccctgcagcccgccgcagcaaagcccgctccccag ctcgaatcgcaggctcaggctcaaatacctgctccggttgaagatgctgcaaattacgta gaaagtgtgagcatctccctgtgggaggcctacaacctgacggagcaggtttcagcagag ggctcacgcgagaggaggggctcgtcgctcatcgccgccagctccgtgtccagtccctct gatcatgaaacagctccagatgtgatggaaaatgttgagaccagtgcagctgtaccaaga gaagtgccaaaaccagtggaaccacctatactggacgaaaaagaagacatggctgttcca caatgtactaagaaactactgaaggtcaaaggcgctcatgaaggcaggacgccgtctcca aagcaccgcgcccacactcccctaaccagcacggtctctggatcagagtcagagggggaa ggtgacaggcgagagacattcgacatgtacgtggcccgagccgactgcagtcctaccggt gggaataaagagcactttgttgtgaaggagggtcagtttgtggaggtcctggactgtgtc caccctgacagatggttggtgagaaccaagcccaccaaaaccaaccctgctcgacagggg tggctctgcccggcctatctagaaaagaagagaaaggagacctttccacatctgagagca cctcatgaagatcttgatggtattgggtccacgggagaagagtacaggagagctctgagc caactggtccaaggcctgattgatggagaggaggagtttgttaaagagatgaagacgttc acatctcaccagctgaattatctggactccagtcgccatgtcccaatcaacatccttaac cagaaggagatcatcttcaggaatattaaggacatcgtatttctgcacgagaggtccatt ctgcctggtctcagagcctgcgccacagatgacgacgtggccgcgcatctgctcaagcac agtgaagactttgagacgtatcttcactacatggtcggccaagctcaagcagaggcctgc gtggctgacaaggctgcccggcagtatttcaatgagttgacagaatgcagcaagcctgat gctgttgtcatggacgtcctcaccttcctccggcgaccagtggagaggatccaaacgtac caggctttattgaaggagttcatcaagaacaaagccaaaagtggtcaaaactgctgtctg ttagaggacgctttctccgtggtgtcctgtctgccctggaggtccgacaatctgcaccaa gtgtccctgatcgagaactacccggcacctctaactgccctgggggagcctgtgcgccag gggatgttcacagtgtgggaggaatcctcggacgataaaaccgcctctagaggtcaccag agacaggtgtttctcttcagagaaagtgtggtgctgtgcaaactgaaaagagacaccagc atcaacagtgacacctgcaccttcaagaacaaaatgaaactgaatgatgtggaaatcaaa gagtccgtgtgtggagatgacaagtcctgggggctgtggcatgaacacagggggtcccta cggaggtacatcctacagagtcgctccgccctggttaaactctcctggctcaaggacctg aaggacctgcagcagcgcttcagcctgccctccaacagcccgccgctgttcgaggcattg ctgtctgacaccacgacaaagatcggacacaccgtcaaactgacctgcagggtcacgggc cttccagcgccggtggtcacctggttcaaagatggcctccccttggaggatgaccccaga cacatcatcgccgcagaccgctccggcacctgtagtctcattctagacagcctcactgca gaggactctggacagtacatgtgctacgctgccagttcactaggcagcgctgggactctg gcaaaggtggtggtccaggctccacccagatttgtgcgtcgcctggagagtgcctgtctg atagaaggagatgatatccagtttacctgctccacactcaccacccctttaccacaaatc aggtggttgaaagctggcagagcgttgactgatcctcagaagtacgccatcctgaatgat gctcgaagtggaatcctgtgtctgactgtcattggcgcaaccaaggcagatattggacag tacgagtgtgagcttcgaaatgagtttggctgcgtgaagtgcaaggcaggactgtgccct gcgtacgtgccgccgattgaatcagagactggccagccacagaatttacctcctaaagat gctgattcagagggctggtccacagcctttgtcaagaaatggctacagactgatttcagc ccgacctctattgccaagatgctgtttcctcctggacaccctgaacaagctgagtgtgga cttgaagaggatgcgcctgcgtctttgtccacggatcagacggcaaagcagccgccgtgc tacatagaggaagaagaggaagaaattttcattccggaaccaatgcaggaaatcacagat gcccctccatccatccaggtacccactgaggacctttatgtagaacctggtcaatcagca acatttacagccatcatcacaggaagacctactcccagggttgagtggtacaaggatggc gaggagcttgcagacaatgagaatgtggagatagcacagcacggtgctcgatgctcgctg accatattttcccctgagggtgaagacagtggcacatacacctgcttcgcccacaacgac tctggccatgcctcgtgccagtctcagctcacggtggaggaaggtccattagaattccag gagagagaagtggagctggggaagagaaggaaactattctctgtgtatgatgtccatgag gaaatgggaaggggaacctttggcgtagtgaagcgggtggttcaccggcggacaggcgag gtcttcgctgccaagttcctgcctttacggggcagcactcggaccagggccttccaggag agagacttgctctcccgtctggctcatcccagggtggcctgtttgctggacttcttctgc accagacggacactggtgctgatcacagaaatttgctgctctcatggacttttggaccat ctactactacaaggatcagtcctagagaaagaggtccagtcgtacattcagcaaatcctt gaaggagttggtcacattcacagcatgaacatcttgcatctggacattaagcctgagaat attctaatggtgtatccaccgagggacgagatcaagatctgtgactttggcttttgtcaa gaaatagacacatccagacaccagtatagcgtgtttggcacaccggagttcattgcccca gagattgttcaccaagagccggtcactgtggccactgatatttgggctgtgggcgtgatg acctacctgtgtctcacatgccgatgcccctttgtgggtgagacagatcgagcgacgctg ctgagagttggggaagggaccctgaactgggaggcccctgatgttacaaacaggagcccc gaagcccagaggttccttcatgctgtgcttcaactagatccagaaaagcgaccgtctgct tttgagtgcttaagtcacgagtggtttcaggatgaacaatcaggagaggatacggatgaa atcaatacaaaaagcctgaaagccttcatttcaaaaagaaagtggcagcgatctttgact tgcattgggtccgtcctcacactgaggcccatccctgagctgctggatgctcctctcaga gacaccgcagtgacagtgacccgtgagcctcaggaccacagcagcagctctgtgagcagc ggctcctcatccgagtatgacgaagccgactcttgggacttttttcaacactgtagccca acggaggaggaagaggaaacagaggaggactatgaccctctgatggagagagcacagatc ccggatcatttttccaaactgcaaccagatgcagaagaggaagaagtaacattaggagag gaagcggatgaggatgtattaggaaggaggagtgtactggaacgcagtgttagcagacag tcagtagcatcgtcagatgtgtcgctacagaccccccagagggagcgcaggttcagcaag gacagcactccatccctgtgcctgtcggacggggatgagggttcaggcagtgatgggagt cgtatccctcggggcagcgtcatccgcagcactttctacagcacctcccatcagctgtcg ccaatgtccgctagacatatgtcactgcgagacaaattccaggctaagaagcaggagaga ggtcgcaagccgctcaggaggagcttctccgggcgtctcaacgagccacttattgaatat gtagaggatgagacagaaaccacccgcagccacagacggggatccatccagcccacggtg cataagttctcctcctttgacagtgcaggtgacctcacccacgccaacgtcccaccgcac agacggagcaggtccctggatgagtcttctcgccggtcccccgactccactccaggtgaa gaaggagggtcccaaagacggagggaagattctacagatgatgagagaacctcaccagcc attctgagtccaagtcgacccccaagaagaagaggatctgtcgctgcagtgcaaagacct ctaatatttggcgcaacgtctggtccctccagcttctgtgctggagaccgaatgaatgcc aagctcgatcaggagcaaaacgagggggatacctttactggctcccaggggtctctggct gggtcttctattttggagcacggcggctctgagtcttcaagtagactcggttcctatgag gagctgagtcatggtcgtttaagaggaaggtgcagatcaggagacagtgatgggtacgat gatcagggagagccgctgatttcatcatccccttgctcgttccaggaagttaaactccga agctcgtttccccaggctccaccacgaaaccgcacccgttctaatcccaacctatctaca ggcagcagaggctactccatgaccccacaacccccgagctccagtcccagcctgtcttct ctccaggctccagagaggcctcccagggccaaggataagaatctaagccacggactccaa aggcatgcctctgctccagccctggaagtgcagccgcccacgggaaaatcacctaagttg ggattcctgaaaatcttccgccggcaatcctggactgaacattcgtactcgaagctggag aacacggggttaggacccacgctaggagagatcatgaagcctgatacacccaccatgtct ctgaggaagaaaatgagagcatcagcctccagcctgaccaagctgttttccaggtcctct agtaaggaggatgtgagtaaaggcccaatagtaaaaggatcaggtcctgtcccgcctgag aggacgcgcagcacgagtctggagagtcccaaaaagaagacccccaaactcctgcagtct tttaaaatacctgcattcaaaaggacaaaagatccaccagctcgtcccagtaaagctgac gtccttcgattagatggaggtggagtcctgttggtttggaaaccagttcagtgtaatgac gctgtcacctactgtgtacaatactgtacagacggtggagagtggacaatgctgtcggag gaggtgacagacagttgtttcgtggcgaaggatttacccagaggagcgtcgtacgtgttc agggtgggctgtgttaccaggacaggagcgggacctttcagcgacgcttcagcacctgtt gtcgttgctactcacactgaagagactcacattccgctcatccagactgaggagttaggg tcaaaggtcactgggtctgaagaacaaacagcacacaggagttacagcttcctctcagag atcggcaggggtcgtttcagcatcataaacctgtgtagggacgcggagaccagccaagtg ttcgctgcaaagatcaccccttaccaggccgagcagaggcagctggtgctgagagagtac cagctgctgaagaggcttcatcaccctcacctgcttcagctccacgctgccttcatcacc tcctgctacatggtgctattggaggagctgtgtcccggcaaggagctgctccacagcctg gctgcgagagatctgtattcggagactcatgttgcagagctcctggctcagattctgaaa gcagtcgactacctgcacagccgccgggtcatccacctggacctgaagtctgacaacatg ttggtggacgattgcaaccaccttaagattgtagactttggctccgcccagccgttcaca cctggacagcccctcgccgtggagcacatccacggcctgacggaaagcaaagtttatatc atccttcctaaagctccagaaatccttgagggtcagggcgtggggcctgaaacagacgtg tgggctgtcggggtcctgtcattcatcatgctgagcgctgacagcccgttccacgcggag ctcagctgggagcaggacaggaacatcaagaaggggaagattcagtttggacggtgctac cctggcctgtcagaaggagccttgagcttcatgaagagcagcctgaataacaagtcttgg gggaggcccactgcagccgagtgtctccagaacccgtggcttcgggcctatcgcacccca cacagagctcgacactccaaagtgtgtttctccacagacaagcttaaagcttatctgcag cagaaggaggagaaacgggagcaggtctgtaccaagctgcagtgtcccttcgtccagtga

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