Bacillus subtilis subsp. subtilis RO-NN-1: I33_2879
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Entry
I33_2879 CDS
T01837
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bsr
Bacillus subtilis subsp. subtilis RO-NN-1
Pathway
bsr00290
Valine, leucine and isoleucine biosynthesis
bsr00620
Pyruvate metabolism
bsr01100
Metabolic pathways
bsr01110
Biosynthesis of secondary metabolites
bsr01210
2-Oxocarboxylic acid metabolism
bsr01230
Biosynthesis of amino acids
Module
bsr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bsr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
I33_2879 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
I33_2879 (leuA)
Enzymes [BR:
bsr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
I33_2879 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Retrotran_gag_2
Motif
Other DBs
NCBI-ProteinID:
AEP91824
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Position
complement(2692534..2694027)
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AA seq
497 aa
AA seq
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MNTQEKLAIAKQLERLGADIIEAGFPASSRGDFLAVQEIARTIKNCSVTGLARCVKGDID
AAWEALKEGAHPRIHVFIATSDIHLKHKLKMTREQVIERAVEMVKYAKERFPIVQWSAED
ACRTELPFLAEIVEKVIDAGASVINLPDTVGYLAPAEYGNIFRYMKENVPNIHKAKLSAH
CHDDLGMAVANSLAAIENGADQIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGIT
LNEIKRTSDLVSKLTGMAVPRNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVT
ADALVLGKHSGRHAFKDRLTALGFQFDSEEINKFFTMFKELTEKKKEITDEDLVSLILEE
KVTDRKIGYEFLSLQVHYGTSQVPTATLSLKNQENAELIQEAATGAGSVEAIYNTLERCI
DKDVELLDYRIQSNRKGEDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQL
VFQSNMSGLKNHTAVGS
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
ttgaatacacaggagaaacttgccatagctaagcagctcgaaagactcggggcagatatc
attgaagcgggatttcccgcttcgtcccgaggtgactttttagctgttcaggaaatcgca
agaaccattaaaaattgttcagtaactggtctggcccgttgtgtaaaaggtgatattgat
gctgcttgggaagcgttaaaagaaggtgctcacccgagaattcatgtttttatcgccaca
tcggatattcatttgaagcacaagctgaaaatgacacgtgagcaagtcattgaaagagcg
gttgaaatggtgaaatacgcaaaagaacgttttccgattgtgcaatggtcagctgaagat
gcctgccgcactgaactgccgtttctagcagaaatcgtcgaaaaagtgattgacgcaggc
gccagtgttatcaatcttccggacactgtcggctacctggctccggcggaatacggaaat
atctttagatatatgaaggaaaacgttccgaacattcacaaagcaaagctttcagcccac
tgtcatgatgatttgggaatggcagtcgcaaactctcttgctgcgattgaaaatggcgct
gatcaaatcgaatgcgctgtgaacgggatcggtgaaagagccggaaacgcggcattagag
gaaattgccgtagccctccataccagaaaagatttctaccaagtcgaaacaggcattaca
ctgaacgagattaagagaacaagtgatttagtaagcaaactgacaggcatggctgtcccg
cgcaacaaagcggttgttggagataatgcatttgctcatgaatcaggcatccatcaggac
ggctttttaaaagaaaaatcgacttatgaaattatttcaccggagcttgtcggcgtaacc
gcagatgcgcttgtcctaggtaaacattccggacgccacgcatttaaagatcggctgact
gctttaggattccaatttgacagtgaagagattaataaattctttacgatgttcaaagag
ttgactgagaagaaaaaagaaatcactgatgaggatcttgtttctcttattttagaagaa
aaagtaacagatcgcaagattgggtatgaatttctttctctgcaagtacattacggaaca
agtcaggtccctacggctactctttcgttgaaaaatcaagaaaacgcagagcttattcag
gaagctgcaactggagctggaagcgtggaagcaatctacaatacgcttgagcgctgcatc
gataaggacgtagagctcttagactaccgcattcagtctaacagaaaaggcgaagatgca
tttgcccaggtgtatgtaagagttttggtgaacggaaaagaatcagcagggcggggcata
gcgcaagacgtattagaagcatcagcgaaagcctatttgaacgcagtcaaccgtcaattg
gttttccagtcgaatatgagcggattgaaaaaccacacagctgtcggatcataa
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