Bacillus subtilis subsp. subtilis JH642: BSUA_00500
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Entry
BSUA_00500 CDS
T03443
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bsul
Bacillus subtilis subsp. subtilis JH642
Pathway
bsul00300
Lysine biosynthesis
bsul00550
Peptidoglycan biosynthesis
bsul01100
Metabolic pathways
bsul01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bsul00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BSUA_00500 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BSUA_00500 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BSUA_00500 (murF)
Enzymes [BR:
bsul01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BSUA_00500 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SIS
NspV
Glyco_hydro_30
VMAP-C
Motif
Other DBs
NCBI-ProteinID:
AIC38827
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Position
492858..494303
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AA seq
481 aa
AA seq
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MKKDTAGKRAVFFPVYTKEREGPYLIKRTVKNIAEMVKGTLANPQYEQTVIHGVATDTRK
LEQHQLFIPLKGERFDGHSFVEQAFEAGVAAVLWDRSVPNPPENHAVILVDDTLTALQQL
AKAYLQELGTRVIGVTGSNGKTTTKDMIHAVLGTQYRVHKTGGNFNNHIGLPLTVLAMPE
NTEIAVLEMGMSAKGEIDLLSRLANPDAAVITNIGESHMQDLGSREGIAEAKLEIINGLK
EDGVLIYIGDEPLLQNAYSCQTKTYGTGTHNDYQLQDVSQSEEGTHFTIKGIENTFFIPI
LGKHNVMNAMAAIAAGAYFGIAPEDAAKGLSGLKVTGMRLELIKTDSGLSIINDAYNASP
TSMKAAIQLTESLEGYGKKMLVLGDMLELGDLEETFHKECGAVISPDKIDRVFTYGKLGA
FIAEGALKHFEKDRVSHYTEKKDLLQAVKENASKGDLILFKASRGMKLEEIVKDLIESPL
S
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaggacactgccggtaaaagggcagtgttttttcccgtatatacaaaagaaaga
gagggaccttacttgattaagcgaacagtaaaaaacattgccgaaatggttaaaggcaca
ctagcaaatccgcaatatgaacaaacagtcattcatggagtggcaaccgatacaagaaaa
ctggaacaacatcagctctttattccgctgaaaggggaacgttttgacggccactctttt
gtggagcaggcctttgaagctggtgtagcggctgttctttgggatcggtcagtaccaaat
ccgcccgagaatcacgccgtcattttagtggacgatacccttactgcacttcagcagctt
gcaaaagcttatttgcaggagcttggcacgcgtgtcatcggagtaaccggaagcaatggc
aaaacgacaacaaaagatatgattcacgccgtattggggacccagtaccgtgtccacaaa
actggaggaaacttcaataatcatatcggtttgccgctgacggttttagcgatgcctgaa
aatacggagatcgccgtattggagatgggaatgagcgccaaaggagaaattgacctcttg
agccgactggcaaacccggatgcggcagtgattacgaatatcggcgaatcgcatatgcaa
gacctcggctctagagagggcatcgcggaggcgaagcttgaaatcataaacgggcttaaa
gaagacggagtgctgatttatatcggggacgaaccgcttcttcaaaatgcatacagctgc
cagacgaaaacgtacggtacgggaacgcataatgattatcagcttcaggatgtcagccag
agtgaggaaggaacccattttacaatcaaagggatagaaaacacgttttttattccaata
ctcggcaagcacaatgtgatgaacgccatggctgcaattgctgcaggggcttattttggc
atcgcgcctgaggatgcggcaaaaggactgagcggcctaaaggtaaccgggatgaggctt
gaactcatcaaaacagacagcggcctttcgataatcaatgacgcttataatgcgagcccg
acttccatgaaagctgcaattcaattgacagaaagccttgaaggctacggcaaaaaaatg
ctcgtgctcggtgatatgcttgaactcggcgatcttgaagaaacgttccataaagagtgc
ggcgctgtgatcagccctgataaaattgaccgcgtctttacgtacggaaaactgggagct
tttatcgcggaaggcgccctgaaacactttgagaaagaccgcgtcagccattacactgag
aaaaaagatctccttcaagctgtgaaggaaaacgcatcaaaaggcgatttgattttattc
aaagcgtccagaggtatgaagcttgaagaaatcgttaaagatttaatagagagcccgctt
tcataa
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