Bacillus subtilis subsp. subtilis JH642: BSUA_01852 Help Entry BSUA_01852        CDS       T03443                                  Symbol pksN Name (GenBank) polyketide synthase   KO K13614   bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksN/BaeN Organism bsul  Bacillus subtilis subsp. subtilis JH642 Brite KEGG Orthology (KO) [BR:bsul00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:bsul01004]     BSUA_01852 (pksN)    01008 Polyketide biosynthesis proteins [BR:bsul01008]     BSUA_01852 (pksN) Lipid biosynthesis proteins [BR:bsul01004]  Polyketide synthase   Modular PKS    BSUA_01852 (pksN) Polyketide biosynthesis proteins [BR:bsul01008]  Polyketide synthase (PKS)   Modular type I PKS    trans-AT PKS     Bacillanene hybrid PKS-NRPS      BSUA_01852 (pksN) SSDB OrthologParalogGFIT Motif Pfam:  ketoacyl-synt KR Ketoacyl-synt_C Condensation PS-DH AMP-binding PKS_DH_N RhiE-like_linker PP-binding CurL-like_PKS_C KAsynt_C_assoc adh_short adh_short_C2 Thiolase_N ACP_SdgA_C Beta-ketacyl_N ApeI-like AMP-binding_C Motif Other DBs NCBI-ProteinID:  AIC40138 LinkDB All DBs Position 1817881..1834425 Genome browser AA seq 5514 aa AA seqDB search MNHKEILDAFRSGELTISEVEEHLKGMKRQLKSPLSEGQKGLWMLQKMSPGMSAYNIPLC FRFSKPIHAETFKKALLFVQRQYPVLASVIQEENGIPFQSVQLSKDLYFVEEDISAMKSA DIMPFLKEKAKEPFQLEAGPLWRTHLFHRLEECIVLITIHHIIFDGVSMLTLISALFEAY QQLLNGIEPLQQPSTADYYDFVDWENRMLTGREGEEHLAYWKEQLSGSLPVLDLPADRPR SSARKFKGQAYKSLLPHHLRNQIKSFARTNHVNESVVFLSIYKVLLHHYTKQKDIIVGVP TMGRQEDRFETLIGYFINMMAVRSKNIGSQPLTAFIRELQLTVAVGLDHAAFPFPALVRE LNVDRSAADSPVFQTAFLYQNFFQATGLQKVLEPYQTLGIEYIEDIRQEGEFELALEIYE QENETVLHLLYNPDLYELSSIESMMENYMKLAQHMMEDPSLPLEAYSLQLNQEQTSLLEQ WNATGTNIANDKCIHEVFEEKAKQTPDAVAVMFEDRSLTYKEVDEKSTSVAVYLQHQGVR PEQPVGICAERSFDMIIGILGILKAGGAYVPLDPSFPQERLKYMLKDSQASIVLTQPNVH DRISGLTGSHVKAINIELACRNGYTDQQSSGLKREVKPEHLAYIIYTSGSTGEPKGVMVE HRSIMNTLNFLESHYPVTAEDAYLLKTNYVFDVSISELFGWFIGDGRLVILPPNGEKSPQ LCMDYIETYKVTHINFVPAMLHVFLEMAKDNKRFTEDGPLKYMMVAGEAFPKVLVKKAVS LFTNCRVENIYGPTEASIYAAYFGCGKGDIASHHTPIGKPVSNTKIYIVDQHLKPVPIGK PGELCIAGAGLARGYFKKPGLTAEKFIDNPFESGTKLYKSGDSARWLPDGNIEYLGRIDS QVKIRGFRVELGAIETKLGEFPGILDQAVVVKQLEGHQQLAAYYTEESGHASANPKDLRL HLKSSLPEYMIPSHFIRLDELPLSPSGKVNRKELEKREIVFNRRKPNHLQLTEIEDQVLR IWEETLKVSGFGPEDGFFDAGGDSLLAVAVAERIKKEFDCEFHVTELFEYSTIRAISEYI LEMKNSDLAGTQNEDDHDDKKDGKYPKQKIPPYFDDSVAIVGISCQFPGAKNHHDFWNHI KEGKESIRFFSEEELRANGVPEELIQHPDYVPVQSVIEGKDLFDPGFFQISPKDAEYMDP QLRLLLLHSWKAIEDAGYVAKEIPATSVYMSASSNSYRTLLPKETTEGHESPDGYVSWVL AQSGTIPTMISHKLGLKGPSYFVHSNCSSSLVGLYQAYKSLTSGESQYALVGGATLHAQS AIGYVHQNGLNFSSDGHVKAFDASADGMAGGEGVAVILLKKAVDAVKDGDHIYAIMRGIG INNDGAEKAGFYAPSVKGQTEVIQHVLDTTKIHPETVSYIEAHGTGTKLGDPIEMSALNK VYKQYTDKTQFCGIGSVKTNIGHLDTAAGLAGCIKVAMSLYHNELAPTINCTEPNPDIKF ESSPFYVVRERKSLEKHAGVHRAALSSFGLGGTNAHAIFEQYENISDAGAENEGNQPYII PISAKNSERLQVYAKEMLSYISQDEQRHFSLRDIAYTFQVGREAMDNRIVFIVNDLEEWK HQLEAFVTGKPLAEGCIQGEKTRMTSAEQLLGNAEADDMASSRISKEELRKLAEMWANGF HVEWRRLYPNIKPRRISLPTYPFAEERYWPESSTGAITTIEPSRLHPLVHHNTSVLSEQR FSSIFTGQEYFIAEHIIKGMAILPAAVTLEMARAAIEQGIGGLEDHETGIRLKNVVWVRP VVAGSEPVQVNIGLYDEDGGHIAYRMYGDPESADAEPVVYNQGKAELIQLKREKALDLSK IKKQCDQSKMDAASFYEGMIGADYGPGYKSVEAVYKGDGQLLAKLSLPESVAHTLGDYVL HPSVMDGALQAAEYLQNVVRAELSDTEDFKAALPFALEELEVFRQCVSDMWVYVQFNSKN KPGDLIQKVDIHLCDEHGMICVRLKGFSTRVMEADIQTEPSKINAETLLLQPVWQEQKAA NSLAAKKYAEHLVFLCEYDHETRKQIEAAIEDVHVYSLEARPSSVDGRFHSYTEQVFKKV QEIIRTKPKDGILVQIVTSAEGEQQLFSGLTGLLKTACQENAKLTGQMIEVSSEESGESI AGKLLENQMSSDSYVKYQNGTRYIADWREIKQAKGDGSKPWKDNGVYLISGGAGGLGHIF AKEIAEQTKNATVILAGRSPLSESKSKKLKELHSKGADITYRQTDVTNKIEVYQLIDDIQ KRYGRLNGILHSAGIIKDSYLVNKQAKDLHDVLAPKVKGLVYLDEASKDLPLDFFILFSS LSGSLGSIGQSDYAAANVFMDMYAGYRNRLADLSQRHGQTLSVNWPLWRDGGMQVDQETE KRLVQLAGIVPMRAEKGIQALYQALHSEANQVMVIEGDVQKIKQNMLAKNASAPMEKKEA EHMTEQINSIDADSLLDKVKAMLKREIAKLLKVKLETIDDHAEMTVYGFDSISMTEFTNH INRAYQLELTPTVFFDHPTIHAFGKHLSEEYQSVFAKTFAVRAVSAQLQPAAKQEQAVRA KAKRRRKQQVMLPNAIQSDAGPEPIAIVGISGIFPMAKDVEAYWNILKEGKDCMTEIPKD RWDWREYEGDPAKEVNKTNVKWGGFIDGIADFDPLFFGISPREAEQMEPQQRLLLTYAWK AIEDAGYSAKRLSGTKTGVFIGTGNTGYSSLLSKANSAIEGSAAANTSPSVGPNRVSYFL NLHGPSEPVDTACSSSLVAIHHAISSIEEGTCDMALAGGVNTIILPEVYISFDKAGALSK EGKCKTFSNQADGFAHGEGAGILFLKKLKAAEEAGDHIYGVIKGSAINHGGRAASLTTPN PKAQADVIQSAYQKAGIDPKTVTYIEAHGTGTELGDPVEINGLKSAFKALGVNEGDTSAN PYCGLGSVKTNIGHLSLAAGAAGVIKILLQLKHKTLVKSLHCENVNPYIQLKNSPFYIVR ETEEWKALKNEQGEELPRRAGVSSFGIGGVNAHVIIEEYIPEASDENIPSIAPEHPGIFV LSAKNEARLKEHAQQLADALDKQTYSDVNLARIAYTLQAGRDAMEERLGIISGSIEDLQK KLKDFAAEKSGVEDVFKGRIDKGTLQMLTEDEEIQEAVEKWMERGKYAKLLELWVKGLDV DWTKLYGENLPKRISLPTYPFAKDRYWISDHIEKSGSIDANQAASRLGGAVLHPLMHQNT SNLSEQRFSSIYTGEEFFLADHVVKGQRILPGVAHLELARAAVEQAAEVQGVPRIMKLKN AVWVRPIVVEDQPQQVHIRLLPGENGEISYEIYGHSDVTGEQSIVYSQGSAVLNPAENLP AVDLQSLREQCQESHFSVNEVYDTYRMIGFEYGPAYRGVKKIYTAEQFVLAKLSLHPSAA DTLSQYKMHPGLMDSALQASSILTGAGDNQLTLPFAVQELEVFGACSSEMWVYARYSQGS KATDKVQKRDMDILDESGNVCVRMKGLSFRAAEGGSGSAESDQTLATLMFEEKWVPKDFK KESPEPHYERHIVMLCDMNGLSKDRIESRMTGAECIVLESFREGLAERFQDYAEQALETV QGLLKSRPQGNVLIQLLTSAQRKQYSFSGLSALLKTAGLENKKLIGQTIEIDSHENVESV IEKLKENKRHTEDQHIKYEKGKRYINDLDEMQIDDREISMPWRDKGVYLITGGAGGLGFI FAKEIARQAEQPVLILTGRSALNADQQAELNELQQLGARAEYRQVDVTQTEAASELITSI TSDYEDLNGVIHSAGLIKDNYLMSKTNEELTQVLAPKVKGLVNVDEATEHLALDFFILFS SISSVAGSAGQADYAMANAFMDSYAAYRNALVTAMYRHGQTLSINWPLWKEGGMRANKEI ENMTLKNTGVTPMRTETGIQALYKGLAFGKDQVIVMEGFKDMMREKLTQKPSSDDVPMKT VQVRVTSEARMDQGNMFDHIQEVLKQTISQLLKIKPEEIDPDMEFNQYGFDSITLTEFAN TLNEKCKLDLTPTVFFEHATVYAFAGYLSEEYPNAFTAQTPAKAEVLMQPVEQNIKNMTF STENRFVKPSVTPMQKEADHKPEPIAIVGMSGVFPKAKDVEEYWKNLSSGADCITEVPKD RWDWQEYYGDPLKEANKTNVKWGGFIDEVADFDPLFFGISPLEAEQMEPQQRLLMTYAWK AVEEAGHSARSLAGTKTGIFIGTGNTGYSSLLSNVDIEGSAAANMSPSAGPNRVSYFLNI HGPSEPIDTACSSSLVAIHHAVCAIENGNCEMAIAGGVNTVVTPQGHIAYDKAGALSKEG RCKTFSDKADGFAVSEGAGILFLKKLTAAERDGDHIYGVIKGSAVNHGGRANSLTTPNPK AQADVVKTAYEKAGIDPRTVTYIEAHGTGTELGDPVEINGLKAAFKELYEKTGDPAVHGS HCGLGSAKTNIGHLSLAAGVAGVIKVLLQLKHKTLVKSLYSETVNPYIRLDDSPFYIVQE SREWQALRDEAGRELPRRAGISSFGIGGVNAHVVIEEYIPKETTHPATAPAVTAQHPGIF ILSAKDEDRLKDQARQLADFISKRSITARDLTDIAYTLQEGRDAMEERLGIIAVSTGDLL EKLNLFIEGGTNAKYMYRGRAEKGIAQTLRSDDEVQKTLNNSWEPHIYERLLDLWVKGME IGWSKLYDGKQPKRISLPTYPFAKERYWITDTKEEAAAHQTALKTVESAALHPLIHVNTS DLSEQRFSSAFTGAEFFFADHKVKGKPVMPGVAYLEMVHAAVTRAVRRTEDQQSVIHIKN VVWVQPIVADGQPVQVDISLNPQQDGEIAFNVYTEAAHNDRKIHCQGSASIRGAGDIPVQ DISALQDQCSLSTLSHDQCYELFKAIGIDYGPGFQGIDRLYIGRNQALAELSLPAGVTHT LNEFVLHPSMADSALQASIGLKLNSGDEQLSLPFALQELEIFSPCTNKMWVSVTSRPNED KIQRLDIDLCDEQGRVCVRIKGITSRLLEEGIQPPDGPTSLGNSKATLNGALLMAPIWDR VQLEKRSISPADERVVILGGDDNSRKAVQREFPFAKELYIEPNASIHRITGQLEALGSFD HIVWMSPSRVTECEVGDEMIEAQDQGVIQMYRLIKAMLSLGYGQKEISWTIVTVNTQYVD QHDIVDPVDAGVHGLIGSMSKEYPNWQTKLIDVKKYEDLPLSQLLSLPADQEGNTWAYRN KIWHKLRLIPVHNNQPVHTKYKHGGVYVVIGGAGGIGEAWSEYMIRTYQAQIVWIGRRKK DAAIQSKLDRFARLGRAPYYIQADAANREELERAYETMKQTHREINGIIHSAIVLQDRSL MNMSEECFRNVLAAKVDVSVRMAQVFRHEPLDFVLFFSSVQSFARASGQSNYAAGCSFKD AFAQRLSQVWPCTVAVMNWSYWGSIGVVSSPDYQKRMAQAGIGSIEAPEAMEALELLLGG PLKQLVMMKMANETNDEAEQTEETIEVYPETHGSAIQKLRSYHPGDNTKIQQLL NT seq 16545 nt NT seq  +upstreamnt  +downstreamnt atgaatcataaagaaattctcgatgccttcagatcaggagaattaaccatttctgaggtg gaagaacatcttaaaggcatgaagcggcagttgaaaagcccgctttcagaagggcaaaaa gggctgtggatgcttcaaaaaatgtctcctgggatgagtgcatataacattcctttatgc tttcgcttcagcaaaccaatacatgcagagacgttcaagaaagcccttctgtttgtacag agacaatatccggtcttagccagtgtgattcaagaagaaaatggcattccatttcaatcg gttcagttatcaaaggatctttattttgtggaagaggatatatcagcaatgaaatcagca gatattatgccttttctaaaagaaaaagcaaaagaacctttccagttggaagctggtccg ttatggcgcacacacctttttcatcggttagaagaatgcattgttcttataacaattcac catatcatatttgatggtgtgtcgatgctgacattgatatcggcgctattcgaagcgtat caacaattgctgaatgggattgaacccttgcagcagccatcaacagctgattattacgat tttgtcgattgggaaaatcgaatgctgactggcagagaaggggaagagcatctcgcttac tggaaagaacagttgtctgggagtctgccagttcttgatttgcctgctgaccgtccgcgg tcttcagcacgaaaatttaaggggcaagcttataaaagcttgctccctcatcacctgaga aatcaaattaaatcgtttgcccgcaccaatcatgtgaatgaatcggttgtgtttctctcc atttacaaagtgctgctgcatcattatacaaaacaaaaggatatcattgttggcgttccg acaatgggtcggcaagaagacagatttgaaaccctaatcggttattttatcaatatgatg gctgttcggagcaagaatatcggatctcagccattaacagcatttattcgggaactgcag ctgacagtggctgtcggcctggatcatgcggcgtttccgttccctgcattggtaagagag ctgaatgtagaccgctcggccgcggattctccggtttttcaaacagcttttctgtaccaa aacttttttcaggcaacaggcttgcaaaaagtgcttgaaccgtatcaaacgcttggcatc gaatatattgaagacattcggcaagagggtgaatttgagctggcgctcgaaatatatgag caagaaaatgaaacagtgcttcatcttctgtacaaccctgatttgtacgaactgtcctcc attgaaagcatgatggagaactatatgaagctcgcgcagcacatgatggaggacccgtct ttgccgcttgaagcctactctttgcaattaaatcaagaacaaactagtttgctggaacaa tggaatgcgacagggacaaacatcgcaaatgacaagtgtatacatgaggtgtttgaggaa aaagcgaaacaaacccccgatgcggttgctgtgatgtttgaagacagatcacttacatat aaagaagtagatgaaaaaagcacatctgtggcagtctaccttcaacatcagggtgttaga cctgaacagcccgttggcatttgtgcagagcgttcgtttgatatgatcatcggaatttta ggaatactgaaagctggcggagcgtatgtgccgttagatccaagttttccgcaagaacga ttaaagtacatgctcaaagacagtcaggcatccattgtcctcacccaacctaacgttcat gataggatcagcggattaactggcagccatgtaaaagcgatcaatatcgagttagcttgc cgaaacggttatacagaccagcaaagcagcggtttaaagcgggaagtaaaaccggaacac ctcgcttatattatttatacatcgggaagcaccggagagcctaaaggggttatggtagag catcggagcattatgaataccctgaattttcttgaatctcactatcctgtaacggctgag gatgcatatttattgaagacgaactatgtgtttgatgtatcgatctcagaattattcgga tggtttattggagatggccgtctagtgattcttccgcctaatggggagaaatcaccgcag ctttgcatggattatattgaaacatataaagtgactcacattaattttgtgccggccatg ctgcatgtttttttagaaatggcgaaagacaacaagcgattcacagaggacggtccgctg aagtatatgatggttgcaggtgaagccttccctaaagtattagtgaaaaaggcggtatcg ctctttacaaactgccgtgttgaaaatatatacggaccgacggaagcctccatttacgct gcgtatttcggatgcggaaaaggagatatcgcaagtcaccatacaccgattggaaagcct gtttccaacacgaaaatttatattgtggaccagcatttgaagcctgtcccgatcggaaag ccaggtgagctttgcatcgctggagccggcttagcaagaggctactttaaaaagccgggg cttacggctgaaaaatttattgataatccctttgaatcagggacgaagctatataaatcg ggtgattcagcaaggtggcttcctgacggcaacatagaatacttgggacggattgacagc caagtcaaaatacgcggttttcgcgtcgagctgggcgcaatagaaacaaagctgggtgaa tttccgggcattttagatcaggcggtagtggtgaagcagcttgagggccatcaacagctc gctgcttattatacagaggaaagcggacatgcctctgccaatccaaaagatttgcgcctt catctaaaatcgagtctgcccgaatatatgataccttcacactttatccgcttagatgag cttccattatcgcccagcggaaaagtgaaccgtaaagaattagaaaaacgcgagatcgtg ttcaacagaaggaaaccaaatcacttgcaattaacggaaatagaggatcaggtgctgcgc atttgggaggaaacgctcaaggtcagcggatttgggccggaagacggatttttcgatgcg ggcggcgattcgcttctggctgtagctgtggctgaacgaatcaaaaaagaattcgattgt gagtttcatgttactgagctgtttgagtattccacgatccgtgcaatcagtgaatacatt ttggagatgaaaaactcagatctagccgggacacaaaatgaagatgatcatgatgacaaa aaagatggaaaatacccgaaacagaagattcccccttattttgacgacagtgttgcgatt gtggggatatcttgccagttcccgggtgcgaaaaatcatcatgacttctggaaccacatc aaagaaggcaaagaaagcatacgattcttttctgaagaagagcttcgcgcaaatggagtt cccgaagaattgatacagcatcctgactatgtgcctgtgcaatctgtgatcgaagggaaa gacttattcgatcccggtttctttcaaatctcgccaaaagatgctgagtatatggaccct cagcttcgcctcttattgctgcactcctggaaagcgattgaagatgcaggatatgtggct aaggagattccggcaacaagtgtatatatgtctgcaagcagcaattcatatagaacgtta ttgccgaaggagacaacagaaggacatgaatcaccggatggctatgtctcttgggtttta gcccaaagcggaaccattcccacaatgatctcacataagctcggattaaaagggccaagc tattttgttcattctaactgttcttcatcactagtcggtttatatcaagcatacaaaagc ctgacatcgggcgaatcacaatatgcgcttgtcggaggcgcaacattgcacgcacaatca gcgatcggctacgtgcaccaaaacgggttgaatttttcaagcgacgggcatgtgaaggcg ttcgatgcttcggcggacggaatggccggaggtgaaggcgtagcagtcatcctgctgaaa aaagctgtggatgccgtaaaagacggagaccatatttatgccattatgcgcggaataggc atcaataatgatggggcagagaaggcaggcttctatgcgccaagtgtaaaaggccaaaca gaagtgatacagcatgtattggatacaaccaagatccatcctgaaacggtcagttatatt gaagcgcacgggacgggaacgaaattaggcgatcctattgaaatgtctgctctaaataaa gtgtacaagcaatacaccgacaaaacacaattttgcggaattggttcagtgaaaacgaat atcggccatttggatacagctgcggggttagccggatgtattaaagttgcgatgagttta taccataatgaacttgcaccgaccatcaactgtacggagccgaatccggatataaagttt gaaagctctcctttttatgttgtccgtgaacgaaaatcgttagagaaacacgcaggtgtc catcgggcggctctgagctcattcggccttggcggaactaacgcccatgcaatatttgag caatatgaaaacatttctgatgcaggtgccgaaaacgaaggcaatcagccttacatcatt cctatatcagcaaaaaatagtgaacggctccaagtatacgcgaaggaaatgctgtcctat atcagtcaagacgagcaaaggcatttctctttaagagatattgcatataccttccaagtc ggccgtgaagcaatggataacaggatcgtttttatagtgaacgatctggaagagtggaaa catcagctggaagcttttgtgactggaaagccgctcgcagaaggctgtattcaaggagaa aaaacgagaatgacatccgctgaacagctgcttggaaatgctgaagcagatgatatggct tcatcgcggatatcaaaagaagaattgagaaagcttgccgagatgtgggcaaatggcttt cacgttgaatggcgcaggctctatccaaatataaagccacgccgcatcagcttgccgaca tacccttttgccgaagaacgatactggcctgaaagcagcaccggcgctatcacaacaatt gaaccatctcgtttgcatcctttggtgcaccataatacatcggttctgtcagagcagcgt ttcagctccattttcacaggacaagagtattttattgccgagcatatcattaaaggcatg gcgattttgccggcggcggtcacgcttgaaatggcaagagccgctatagaacaaggaatt ggcggattggaggatcatgaaactggaatcaggctgaaaaatgtcgtgtgggttcgcccg gttgtagcaggaagtgagccggttcaggtaaatatcggactttacgatgaagatggcgga catattgcttatcggatgtatggtgatccggaatccgctgatgcagaaccagttgtatat aaccaaggtaaagcggaattgattcagttaaagcgagaaaaagcactggatctttctaag atcaagaaacaatgtgatcaaagcaaaatggatgctgcctcgttttatgaagggatgatc ggcgccgattacggtccaggttacaagagtgtagaggccgtatataaaggcgacggccag ctgcttgccaaattatcactgccagaatctgttgcacatacgttgggcgattatgttctt catccaagtgtaatggacggggcgttacaggcggctgaatatttgcaaaatgtcgtcaga gcggaactttcagacactgaagactttaaggcagcactgccatttgcactggaggaactt gaggtttttcgtcagtgcgtttctgacatgtgggtttatgttcaattcaactcgaaaaac aaaccaggagatttgatacagaaagtcgatattcacctatgtgatgagcatggcatgatc tgtgtgcggctgaaaggattttcgacgagagtgatggaggcagatatacaaaccgaacca tcaaaaatcaacgctgaaactttattgcttcagcccgtttggcaagaacaaaaggctgct aacagcttagctgcaaaaaaatatgcagagcatctcgtattcctatgtgaatatgatcat gagacgagaaaacaaattgaagcagccatcgaggatgtccatgtatacagcctggaagca aggccttcttcagtagatgggcgtttccattcttatacagaacaagtgtttaaaaaggta caagagatcattcgtacgaaaccgaaagacggcattctcgttcagatcgtgacctctgcc gagggagaacagcaattgttttcagggttgacaggactgctgaaaacagcttgtcaggaa aatgccaaactaaccggccaaatgattgaagtcagcagtgaagaaagtggagaaagcatt gctggcaaactgttagaaaatcaaatgagcagcgattcatatgtcaaatatcaaaacggg acacggtatattgctgattggcgtgaaatcaaacaggcaaaaggagacggcagcaaaccg tggaaagacaatggcgtttatctcatttcaggaggtgccggcggactaggtcatattttt gcaaaggaaattgcggaacaaacgaaaaatgcgacagtcattctggcgggccgctcacct cttagcgaaagcaaaagcaaaaagctgaaagagcttcatagcaagggggctgacatcacc taccggcaaacagatgttaccaataaaattgaagtctatcagctcattgacgacattcaa aaaagatatggccgtctgaacggtattcttcatagtgccggaatcatcaaggacagctac ctggttaataaacaggcaaaagatctgcacgatgtactggcgcctaaagtaaaagggctt gtttatctagacgaagcgagtaaggatttgcctttagacttctttattctcttttcatct ctttcaggaagtttagggagcattggtcagtctgactatgcggcagccaatgtatttatg gatatgtatgcaggctatcgaaataggcttgccgacctcagccagcggcatgggcagacg ctttctgtaaactggcctttatggagagatggaggcatgcaggtcgatcaagaaactgag aaaaggcttgtgcaacttgccggtattgttcctatgagggcggaaaaaggaattcaggca ttatatcaagcacttcattcagaggcaaaccaagtaatggtgatcgaaggcgatgtgcag aaaataaaacaaaacatgctggccaaaaacgcctcagcacctatggaaaagaaggaagca gaacacatgactgaacaaataaatagcattgatgcagacagtttgctggataaagtaaag gcgatgttaaagcgagagatcgccaagctgttaaaggtcaagcttgaaacgattgacgat catgcagagatgacggtgtatggttttgattctatctccatgactgaattcaccaaccat atcaatcgcgcctatcagttagagctgacgccaaccgtattttttgaccacccgacgatt catgcgtttggcaagcatttgtcagaagaatatcaatcggtatttgcgaagacatttgct gtgcgcgctgtatcggctcagcttcagcctgctgcgaaacaggaacaagccgtgcgtgcc aaagctaaaagacgcagaaagcagcaagtcatgctgccaaacgccatacagagtgatgct gggcctgagccaattgccattgtgggcataagcgggattttccctatggcgaaagacgtt gaggcgtactggaacatcttaaaagagggcaaagactgcatgacggaaatcccgaaagat cgctgggattggcgtgaatatgaaggtgatccggcgaaggaagtcaataaaacgaacgtg aaatggggcggttttattgacggtattgcagattttgatccattattctttggcatttcc ccgcgtgaagctgaacaaatggaacctcagcagcgcttactgctgacttacgcctggaaa gcgatcgaagatgcaggatattcggcgaaaaggttgtcaggcacaaaaaccggcgtcttc atcggaacgggaaatacaggatacagctctcttctatctaaagcgaactcggcaatagaa ggatcagcggcagccaatacgagcccatcggtcggtccgaaccgggtcagttatttcctt aatctgcatgggccgagcgaaccggttgatacagcgtgctcaagttcactagtggcgatc caccatgccatctcttcaattgaggaaggcacttgtgacatggcattagccggcggtgta aatacgattatccttcctgaggtgtatatcagctttgataaggcgggagcactgagcaaa gaaggaaaatgcaagacgttttcaaatcaagccgatggttttgcacatggggaaggtgcc ggcatactgttcctgaaaaaattaaaagcggctgaagaagcgggagaccatatttacgga gtcataaaaggcagtgcaatcaatcacggcggccgtgcagcctctttaacgactcccaat ccgaaggcgcaggcagatgttattcagtcggcatatcaaaaagcgggaatcgacccgaaa accgtgacctacattgaagcccacggaaccggaacggagcttggagacccggttgaaatt aacggtttgaaatcagcttttaaagcattgggtgtaaatgaaggagacacatcagccaat ccttactgcggattagggtctgtaaagacaaacatcggccacttatcgctggcagccggt gcagcaggagttattaaaatattattgcagcttaagcataaaaccttagtgaaaagtctg cattgcgaaaacgtgaatccatacattcagctgaaaaacagtccgttctatatcgtacgg gaaacggaagaatggaaagcgctgaaaaatgaacagggagaagagcttcctcgacgggca ggtgtcagttcatttggaatcggcggagtaaacgcccacgtgattatcgaggaatatatt ccggaagcatccgatgagaatataccatccatcgcgccggaacatccgggtatcttcgtt ttatcggctaaaaatgaagcgcggctaaaagaacatgcacagcagctggcagatgcgctt gataagcaaacatatagtgacgtaaatctcgcccgaatcgcttatacactgcaagccgga cgggatgcgatggaagaacgtctcgggattatttccggttccattgaggatttacagaaa aagttaaaagactttgcagcggagaaaagcggtgtggaggatgtatttaaaggcaggatt gataaaggcacactccaaatgctgacagaggacgaagagattcaagaagccgtcgagaaa tggatggaacggggaaagtatgcaaaattgcttgaattatgggtaaaagggcttgatgta gactggacgaaattgtatggcgagaatctgccaaagcgcatcagcttgccgacgtatcct ttcgcaaaagaccgttattggatctctgatcatattgaaaaaagcggcagcattgatgca aatcaagcagcctcccgccttggcggagccgtgctgcatccattaatgcatcaaaacaca tccaatctctcggaacaaaggtttagctctatttatacgggagaagagtttttccttgct gatcatgttgtgaaaggccaacggattttgccgggagtggctcatcttgaattggcgcgg gcagctgttgagcaggccgcagaggtacaaggtgtaccgcgcatcatgaagctaaagaat gcggtgtgggtgcggcctattgttgtagaggatcagccgcagcaagtacacattaggctt ttaccgggagaaaatggtgagatctcttatgaaatctatggtcattcagacgttactggc gaacagtcaatcgtctacagtcaaggcagcgcggtattgaatcctgctgaaaatttgccg gcggttgatttgcaatctctgcgggagcagtgtcaggaaagtcatttcagcgtaaacgaa gtatacgacacctatcgaatgattggatttgaatatggtcctgcttatcgcggagtgaaa aaaatctatacagctgaacaatttgttttggcaaaattgtcattgcatccgtcagctgca gatacgctcagccaatacaaaatgcaccctgggctgatggattctgctttgcaggcgtca agcattttgacaggagccggggataaccagctgacactgccttttgcggtccaggagctt gaagtcttcggagcatgttcgtcagaaatgtgggtatacgcaagatacagccaaggcagc aaggcaactgataaggtgcaaaagcgcgatatggatattttagatgagagcggcaatgtt tgcgtacggatgaaaggattatctttcagagcagcagaaggcggctctggatcggcggaa tctgatcaaacgctggcaaccctgatgtttgaagaaaaatgggtgcccaaggattttaaa aaagaaagtcctgagcctcattacgaacggcacattgtcatgctttgcgacatgaatggc ctctcaaaagatcgcattgaatcaagaatgacaggagcggaatgcatcgttttggagtca ttccgcgaaggacttgcagagaggttccaagattatgccgaacaagcgcttgagacggtc cagggtcttctcaaaagcagacctcagggcaatgttctgatccagctgcttacctctgca caaagaaagcagtactcattctcagggctatcggcgctccttaaaaccgccggcctggag aataaaaaactaatcggccagacgattgaaatcgattcacatgaaaatgttgaaagtgta atagaaaaactgaaagagaataaaaggcacacagaagatcagcacatcaaatatgaaaaa ggcaaacggtacatcaatgatctggatgaaatgcaaatagatgatcgggaaataagcatg ccgtggagagataaaggtgtatacctcatcacgggcggcgcaggaggacttgggtttatt tttgcaaaagagattgctcgccaagccgaacagcctgtgctcattctgacaggcagatcc gcgttgaatgcggatcagcaggcggagcttaacgaacttcagcaattaggggctcgcgca gaatacaggcaggttgacgtgacacaaacggaagcagcctccgagcttatcacaagcatt acgtctgattacgaagacttgaatggtgtcattcacagcgctgggctgattaaagataac tatcttatgagcaaaaccaatgaagagctgacacaagttctcgctcctaaggtgaaaggg cttgtgaatgtggatgaggcaaccgagcatcttgcgttagatttctttatcctcttttct tcaatatcaagtgttgccggcagcgcgggacaggccgattatgcaatggctaatgcattt atggacagttatgctgcttatcggaatgcgcttgtaaccgccatgtacaggcacggacaa acgttgtcaatcaattggccgctctggaaagaaggcggcatgcgcgcgaataaagaaatt gaaaacatgacgttgaaaaacacaggtgtgactccaatgcggaccgagaccggcattcaa gcgctgtataaaggtttggcatttggcaaagatcaagtcatcgtcatggaaggattcaaa gacatgatgagggaaaagctgactcaaaagccgtcttctgatgatgtaccaatgaaaaca gtgcaagtacgggtgacatctgaagcaagaatggatcaagggaatatgtttgaccacatt caagaagttttaaagcaaacaatctctcaattgctcaaaatcaaacctgaagagattgac ccggacatggagtttaatcaatatggatttgattcgattacgttaactgaattcgcaaat acactgaatgagaagtgcaagctggatcttacgcctacggtcttctttgagcacgcaact gtttatgcatttgcagggtatctgtcagaagaatatccaaatgcttttacagctcaaacg cctgccaaagctgaggtgctgatgcagcctgtcgaacagaatataaaaaatatgacgttt tcgactgaaaaccgctttgtaaaaccttcggtaacaccaatgcaaaaggaagctgatcac aagcctgagcctattgcgattgtggggatgagcggcgttttcccaaaggcaaaagacgtt gaggaatattggaagaacctgtcatcgggcgcagattgtattacagaggttccaaaagac cgctgggattggcaggagtattacggagaccctctgaaagaagcgaataaaacaaacgtc aaatggggcggttttattgatgaagttgctgactttgatccattgttcttcggcatatct ccgctggaggctgagcagatggagcctcagcagcgcctgttaatgacctatgcgtggaag gcggtagaagaagcgggacactcagcgagaagcctggcaggaaccaaaacgggcatcttc atcgggacaggaaacacagggtacagttcacttctgtcaaatgtagacatcgaaggctca gcggctgcgaatatgagtccttctgcaggaccgaatagagtcagttatttcctgaacatt catgggccgagtgaaccgatcgacactgcgtgctcaagctctttggtcgccattcatcat gcggtttgcgccattgaaaatggaaactgtgaaatggcgattgcgggaggggtcaacacg gtcgtaactccgcaaggccatatcgcctatgataaagccggggcgctgagcaaagaagga agatgcaaaacattttctgacaaagccgatggattcgcagtcagtgaaggtgccggcatt ctctttctgaaaaagctgacagcggctgaacgagacggtgatcatatttacggtgtcatt aaaggaagtgcggtaaaccacggtggccgcgcaaattctctaacgactcctaatccgaaa gctcaggcggatgtcgtaaaaacagcatatgaaaaagcgggaattgatccaagaaccgta acttatattgaagcgcatgggactggaacagagctgggcgatccagtagaaatcaacggc ttaaaagcggcatttaaagagctgtatgaaaaaacgggggacccggctgttcatggcagc cattgcggacttgggtcagcgaaaacaaacatcggtcacttatcactggcggccggtgtg gctggtgtcattaaagtgttattgcagctcaagcataaaacgcttgtcaaaagtctgtac agtgaaactgttaatccgtatatcagactggatgacagcccgttttatattgtgcaggaa tcgagagagtggcaggcgcttcgggatgaagccggccgagagctgccgcgccgcgcaggt atcagttcgttcgggataggcggcgtcaatgcccacgtggtcattgaggaatatattccg aaagaaacaacccatcctgcaacagcaccagccgtgacagcacagcacccgggcatcttt attttgtcggcaaaggatgaagatcgtctgaaagaccaagcccggcaattagcagacttt atcagcaagcgatctatcactgctcgtgacctcactgatattgcttatacactccaagag gggcgtgatgcaatggaggagagattagggatcatcgctgtctcgactggggacttgctg gaaaaactgaacctctttatagaagggggcaccaatgcgaagtacatgtacagaggcaga gcagaaaaaggtatcgcacaaacattgagatcagatgacgaagtacagaaaacgctcaac aatagctgggagcctcacatatatgaaagactgcttgatttatgggtaaaaggcatggaa ataggctggagtaaactgtatgacggcaaacagccgaaacgcatcagcctccctacctat ccatttgcgaaagaacgctactggataacggatacgaaagaggaggcagccgcccatcaa acagctttaaaaacagtcgaatcagcagctttgcatccattgatacatgtcaacacatct gatttgtcagagcagcgtttcagctcggcctttacaggtgctgagttctttttcgccgat cataaggtgaagggaaaaccggttatgccgggcgtggcatatcttgagatggttcatgct gccgttacaagagcagtgagaagaaccgaagatcaacaatctgttattcacatcaaaaat gttgtgtgggtgcagccgattgtggcggatggccagcctgttcaagtggatatcagtcta aatccccagcaggacggcgagattgcttttaacgtctatacagaggctgcacacaatgat cgaaagatacattgtcaaggcagtgcttcaatccgtggggcaggagacattccagtccag gatatcagcgcgcttcaagaccaatgcagtttaagcacactctcacacgaccagtgttat gaattgtttaaggcgatcggcattgactacggacctggttttcaagggatagatcggctt tacatcggccgcaatcaagccttggcagagctttctctgcctgctggtgtaactcacaca ctgaatgaattcgttcttcatccaagtatggccgactctgctttacaagcgtcgatcggg ctaaagctgaattccggtgacgagcagctttctctgccttttgcgctgcaagagctagaa atattcagcccgtgtacaaataaaatgtgggtgtctgtgacatctcgtcctaatgaggac aaaatacagagactggatattgatttgtgtgatgaacaaggccgagtgtgtgtaagaatc aaggggattacctcaaggctgctggaagaaggcatacaaccgccagacgggccgacatca ctaggaaactccaaagcaactcttaacggagcgcttcttatggcgccgatatgggatcga gtgcagctggagaagaggagcatttcgcctgctgatgagcgtgttgtcatcctcggaggg gatgacaacagcagaaaagctgttcaaagggagtttccgtttgccaaggagctgtacatt gagccgaacgcatcaattcatagaattacaggccagcttgaagcactcggatcgtttgac cacatcgtgtggatgtctccttctcgtgtgacagagtgcgaagtcggcgatgaaatgatt gaagcccaagatcaaggcgtcattcaaatgtataggctcattaaggcaatgctttcttta ggctatggacagaaggagataagctggacgatcgtgacggtgaacacacaatatgttgat cagcatgatattgtcgacccggtcgatgccggggtgcacggcctgatcggttcaatgtca aaagaatatccaaattggcagacaaagctgatcgatgttaaaaaatacgaagacctgccg ttatctcaactcctttccttgcctgccgatcaagaagggaatacgtgggcctatcgaaac aagatttggcataagcttcgtctaattccagtacacaacaatcaaccggtgcacacgaag tataagcacggaggtgtttatgttgtcataggcggagctggcggtattggtgaggcgtgg agtgaatatatgatcagaacatatcaggcgcagatcgtttggattggcagaaggaaaaag gatgcagccattcaaagcaagctggacagatttgcacgtctagggcgagccccgtattac attcaagcagatgcggctaaccgagaggaattagaacgcgcgtatgaaacaatgaaacaa acacatcgtgaaatcaacggcatcatccattctgcaattgtcttacaagaccgaagcctg atgaatatgagtgaggaatgtttcagaaacgttcttgctgcaaaggttgatgtaagcgtg cgaatggctcaagttttccggcatgaaccactggattttgttttgtttttctcttccgta caatcgtttgcaagagcttccggacaaagcaattacgctgcgggttgcagttttaaggat gcttttgcacagcggctttctcaagtatggccttgtacagtagccgtgatgaattggagt tattggggaagcattggtgttgtttcatcaccggattaccaaaagagaatggctcaggca ggcataggctcaattgaagcccctgaagcaatggaagctttggaattgctgctcggggga ccgctgaagcagctagtaatgatgaaaatggcaaacgaaacgaatgatgaagcggaacag acagaagaaacgattgaagtgtacccggaaactcacggctccgccattcaaaagctgcga agctatcacccgggtgacaacacaaagattcaacaactgttatag

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