KEGG   Bacillus subtilis subsp. subtilis OH 131.1: Q433_09785
Entry
Q433_09785        CDS       T03469                                 
Symbol
baeN
Name
(GenBank) polyketide synthase
  KO
K13614  bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksN/BaeN
Organism
bsus  Bacillus subtilis subsp. subtilis OH 131.1
Brite
KEGG Orthology (KO) [BR:bsus00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:bsus01004]
    Q433_09785 (baeN)
   01008 Polyketide biosynthesis proteins [BR:bsus01008]
    Q433_09785 (baeN)
Lipid biosynthesis proteins [BR:bsus01004]
 Polyketide synthase
  Modular PKS
   Q433_09785 (baeN)
Polyketide biosynthesis proteins [BR:bsus01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   trans-AT PKS
    Bacillanene hybrid PKS-NRPS
     Q433_09785 (baeN)
SSDB
Motif
Pfam: ketoacyl-synt KR Ketoacyl-synt_C Condensation PS-DH AMP-binding PKS_DH_N RhiE-like_linker PP-binding CurL-like_PKS_C KAsynt_C_assoc adh_short adh_short_C2 Thiolase_N DUF7080 Beta-ketacyl_N AMP-binding_C Polysacc_synt_2 GDP_Man_Dehyd Thioredoxin_2 DUF1307
Other DBs
NCBI-ProteinID: AIC98257
LinkDB
Position
1777040..1793584
AA seq 5514 aa
MNHKEILDAFRSGELTISEVEEHLKGMKRQLKSPLSEGQKGLWMLQKMSPGMSAYHIPLC
FRFSKPIHAETFKKALLFVQKQYPVLASVIQEENGVPFQSVQLSKDLCFVEEDISAMKSA
DIFPFLKEKAKEPFQLDAGPLWRTHLFHRLEECIVLITIHHIIFDGVSMLTLISALFEAY
QQLLNGIEPLQQPSTADYYDFVDWENRMLTGREGEEHLAYWKEQLSGSLPVLDLPADRPR
SSARKFKGQAYKSLLPHHLRNQIKSFARTNHVNESVVFLSIYKVLLHHYTKQKDIIVGVP
TMGRQEDRFETLIGYFINMMAVRSKNIGSQPLTAFIWELQLTVADGLDHAAFPFPALVRE
LNVDRSAADSPVFQTAFLYQNFFQATGLQKVLEPYQTLGIEYIEDIRQEGEFELALEIYE
QENETVLHLLYNPDLYELSSIESMMENYMKLAQHMMEDPSLPLEAYSLQLNQEQTSLLEQ
WNATGTNIANDKCIHEVFEEKAKQTPDAVAVMFEDRSLTYKEVDEKSTSVAVYLQHQGVG
PEQPVGICAERSFDMIIGILGILKAGGAYVPLDPSFPQERLEYMLKDSQASIVLTQPNVH
DRISGLTGSHVKAINIELACRNDYTDQQSSGLKREVKPEHLAYIIYTSGSTGEPKGVMVE
HRSIMNTLNFLESHYPVTAEDAYLLKTNYVFDVSISELFGWFIGDGRLVILPPNGEKSPQ
LCMDYIETYKVTHINFVPAMLHVFLEMAKDNKRFTEDGPLKYMMVAGEAFPKELVKKAVS
LFTNCRVENIYGPTEASIYAAYFGCGKGDIASHHTPIGKPVSNTKIYIVDQHLKPVPIGK
PGELCIAGAGLARGYFKKPGLTAEKFIDNPFEPGTKLYKSGDSARWLPDGNIEYLGRIDS
QVKIRGFRVELGAIETKLSEFPGILDQAVVVKQLEGHQQLAAYYTEESGHASANPKDLRL
HLKSSLPEYMIPSHFIRLDELPLSPSGKVNRKELEKREIVFNRRKPNHLQLTEIEDQVLR
IWEETLKVSGFGPEDGFFDAGGDSLLAVAVAERIKKEFDCEFHVTELFEFSTIRAISEYI
LEMKNSDLAGTQNEDHYDIKKDRKHLEQKIPPYFDDSVAIVGISCQFPGAKNHHDFWNHI
KEGKESIRFFSEEELRANGVPEELIQHPDYVPVQSVIEGKDLFDPGFFQISPKDAEYMDP
QLRLLLLHSWKAIEDAGYVAKEIPATSVYMSASSNSYRTLLPKETTEGHESPDGYVSWVL
AQSGTIPTMISHKLGLKGPSYFVHSNCSSSLVGLYQAYKSLTSGESQYALVGGATLHAQS
AIGYVHQNGLNFSSDGHVKAFDASADGMAGGEGVAVILLKKAVDAVKDGDHIYAIMRGIG
INNDGAEKAGFYAPSVKGQTEVIQHVLDTTKVHPETVSYIEAHGTGTKLGDPIEMSALNK
VYKQYTDKTQFCGIGSVKTNIGHLDTAAGLAGCIKVAMSLYHNELAPTINCTEPNPDIKF
ESSPFYVVRERKSLEKHAGVHRAALSSFGLGGTNAHAIFEQYENISDAGTENEGNQPYII
PISAKNSERLQVYAKEMLSYISQDEQRHFSLRDIAYTFQVGREAMDNRIVFIVNDLEEWK
HQLEAFVTGKPLAEGCIQGEKTRMTSAEQLLGNAEADDMASSRISKEELRKLAEMWANGF
HVEWRRLYPNIKPRRISLPTYPFAEERYWPESSTGAITTIEPSRLHPLVHHNTSVLSEQR
FSSIFTGQEYFIAEHIIKGMAILPAAVTLEMARAAIEQGIGGLEDHETGIRLKNVVWVRP
VVAGSEPVQVNIGLYDEDGGHFPYRMYGEPESADAEPVVYNQGIAELIQLKREKALDLSK
IKKQCDQSRMDAASFYEGMIGADYGPGYKSVEAVYKGDGQLLAKLSLPESVAHTLGDYVL
HPSVMDGALQAAEYLQNVVRAELSDTEDFKAALPFALEELEVFRQCVSDMWVYVQFNSKN
KPGDLIQKVDIHLCDEHGMICVRLKGFSTRVMEADIQTEPSKINAETLLLQPVWQEQKAA
DSLAAKKYAEHLVFLCEYDHETRKQIEAAIEDVHVYSLEARPSSVDGRFHSYTEQVFKKV
QEIIRTKPKDGILVQIVTSAEGEQQLFSGLTGLLKTACQENAKLTGQMIEVSSEESGESI
TGKLLENQMSSDSYVKYQNGTRYIADWREIKQAKGDASKPWKDNGVYLITGGAGGLGHIF
AKEIAEQMKNATVILAGRSPLSESKSKKLKELHSKGADITYRQTDVTNKIEVYQLIDDIQ
KRYGRLNGILHSAGIIKDSYMVNKQAKDLHDVLAPKVKGLVYLDEASKDLPLDFFVLFSS
LSGSLGSIGQSDYAAANVFMDMYAGYRNRLAGLSQRHGKTLSVNWPLWRDGGMQVDQETE
KRLVQLAGIVPMRAEKGIQALYQALHSEANQVMVIEGDVQKIKQNMLAKNASAPMEKKEA
EHMTEQINSIDTDSLLDKVKAMLKREIAKLLKVKLETIDDHAEMTVYGFDSISMTEFTNH
INRAYQLELTPTVFFDHPTIHAFGKHLSEEYQSVFAKTFAVRAVSAQLQPAAKQEQAVRA
KAKRRRKQQVMLPNAIQSDAGPEPIAIVGISGIFPMAKDVEAYWNILKEGKDCMTEIPKD
RWDWREYEGDPAKEVNKTNVKWGGFIDGIADFDPLFFGISPREAEQMEPQQRLLLTYAWK
AIEDAGYSAKRLSGTKTGVFIGTGNTGYSSLLSKANSAIEGSAAANTSPSVGPNRVSYFL
NLHGPSEPVDTACSSSLVAIHHAISSIEEGTCDMALAGGVNTIILPEVYISFDKAGALSK
EGKCKTFSNQADGFAHGEGAGILFLKKLKAAEEAGDHIYGVIKGSAINHGGRAASLTTPN
PKAQADVIQSAYQKAGIDPKTVTYIEAHGTGTELGDPVEINGLKSAFKALGVNEGDTSAN
PYCGLGSVKTNIGHLSLAAGAAGVIKILLQLKHKTLVKSLHCENVNPYIQLKNSPFYIVR
ETEEWKALKNEQGEELPRRAGVSSFGIGGVNAHVIIEEYIPEASDENIPSIAPEHPGIFV
LSAKNEARLKEHAQQLADALDKQTYSDVNLARIAYTLQAGRDAMEERLGIISGSIEDLQK
KLKDFAAEKSGVEDVFKGRIDKGTLQMLTEDEEIQEAVEKWMERGKYAKLLELWVKGLDV
DWTKLYGENLPKRISLPTYPFAKDRYWISDHIEKSGSIDANQAASRLGGAVLHPLMHQNT
SNLSEQRFSSIYTGEEFFLADHVVKGQRILPGVAHLELARAAVEQAAEVQGVPRIMKLKN
AVWVRPIVVEDQPQQVHIRLLPGENGEISYEIYGHSDVTGEQSIVYSQGSAVLNPAENLP
AVDLQSLREQCQESHFSVNEVYDTYRMIGFEYGPAYRGVKKIYTAEQFVLAKLSLHPSAA
DTLSQYKMHPGLMDSALQASSILTGAGDNQLTLPFAVQELEVFGACSSEMWVYARYSQGS
KATDKVQKRDMDILDESGNVCVRMKGLSFRAAEGGSGSAESDQTLATLMFEEKWVPKDFK
KESPEPHYERHIVMLCDMNGLSKDRIESRMTGAECIVLESFREGLAERFQDYAEQALETV
QGLLKSRPQGNVLIQLLTSAQRKQYSFSGLSALLKTAGLENKKLIGQTIEIDSHENVESV
IEKLKENKRHTEDQHIKYEKGKRYINDLDEMQIDDREISMPWRDKGVYLITGGAGGLGFI
FAKEIARQAEQPVLILTGRSALNADQQAELNELQQLGARAEYRQVDVTQTEAASELITSI
TSDYEDLNGVIHSAGLIKDNYLMSKTNEELTQVLAPKVKGLVNVDEATEHLALDFFILFS
SISSVAGSAGQADYAMANAFMDSYAAYRNALVTAMYRHGQTLSINWPLWKEGGMRANKEI
ENMTLKNTGVTPMRTETGIQALYKALAFGKDQVIVMEGIKDMMREKLTQKPSSDDVPMKT
VQVPVTSEARMDQGNMCDHIQEVLKQTISQLLKIKPEEIDPDMEFNQYGFDSITLTEFAN
TLNEKYKLDLTPTIFFEHATVYAFAGYLSEEYPNAFTAQTPAKAGVLMQPVEQNIKNMTF
STENRFVKPSVTPMQKEADPKPEPIAIVGMSGVFPKAKDVEEYWKNLSSGTDCITEVPKD
RWDWQEYYGDPLKEANKTNVKWGGFIDEVADFDPLFFGISPLEAEQMEPQQRLLMTYAWK
AVEEAGHSARSLAGTKTGIFIGTGNTGYSSLLSNVDIEGSAAANMSPSAGPNRVSYFLNI
HGPSEPIDTACSSSLVAIHHAVCAIENGNCEMAIAGGVNTVVTPQGHIAYDKAGALSKEG
RCKTFSDKADGFAVSEGAGILFLKKLTAAERDGDHIYGVIKGSAVNHGGRANSLTTPNPK
AQADVVKTAYEKAGIDPRTVTYIEAHGTGTKLGDPVEINGLKAAFKELYEKTGDPAVHGS
HCGLGSAKTNIGHLSLAAGVAGVIKVLLQLKHKTLVKSLYSETVNPYIKLDDSPFYIVQE
SREWQALRDEAGRELPRRAGISSFGIGGVNAHVVIEEYIPKETTHPATAPAVTAQHPGIF
ILSAKDEDRLKDQARQLADFISKRSITARDLTDIAYTLQEGRDAMEERLGIIAVSTGDLL
EKLNLFIEGGTNAKYMYRGRAEKGIAQTLRSDDEVQKTLNNSWEPHIYERLLDLWVKGME
IGWSKLYDGKQPKRISLPTYPFAKERYWITDTKEEAAAHQTALKTVESAALHPLIHVNTS
DLSEQRFSSAFTGAEFFFADHKVKGKPVMPGVAYLEMVHAAVIRAVRRTEDQQSVIHIKN
VVWVQPIVADGQPVQVDISLNPQQDGEIAFNVYTEAAHNDRKIHCQGSASIRGAGDIPVQ
DISVLQDQCSLSTLSHDQCYELFKAIGIDYGPGFQGIDRLYIGRNQALAELSLPAGVTHT
LNEFVLHPSMADSALQASIGLKLNSGDEQLSLPFALQELEIFSPCTNKMWVSVTSRPNED
KIQRLDIDLCDEQGRVCVRIKGITSRLLEEGIQPPDGPTSLGNSKATLNGALLMAPIWDR
VQLEKRIISPADERVVILGGDDNSRKAVQRQIPFAKELYIEPNASIHRIAGQLEALGSFD
HIVWMSPSRVTECEVGDEMIEAQDQDVIQMYRLIKAMLSLGYGQKEISWTVVTVNTQYVD
QHDIVDPVDAGVHGLIGSMSKEYPNWQTKLIDVKKYEDLPLSQLLSLPADQEGNTWAYRD
KVWHKLRLIPVHNNQPVHTKYKHGGVYVVIGGAGGIGEAWSEYMIRTYQAQIVWIGRRKK
DAAIQSKLDRLARLGPAPYYIQADAANREELERAYETMKQTHHEINGIIHSAIVLQDRSL
MNMSEECFRNVLAAKVDVSVRMAQVFRHEPLDFVLFFSSVQSFARASGQSNYAAGCSFKD
AFAQRLSQVWPCTVAVMNWSYWGSIGVVSSPDYQKRMAQAGIGSIEAPEAMEALELLLGG
PLKQLVMMKMANETNDEAEQTEETIEVYPETHGSAMQKLRSYHPGDSTKIQQLL
NT seq 16545 nt   +upstreamnt  +downstreamnt
atgaatcataaagaaattctcgatgccttcagatcaggagaattaaccatttctgaggtg
gaagaacatcttaaaggcatgaagcggcagttgaaaagcccgctttcagaagggcaaaaa
gggctgtggatgcttcaaaaaatgtctcctgggatgagtgcatatcatattcctttatgc
tttcgcttcagcaaaccaatacatgcagagacgttcaagaaagcccttctgtttgtacag
aaacaatatccggtcttagccagtgtgattcaagaagagaatggcgttccatttcaatcg
gttcagttatcaaaggatctttgttttgtggaagaggatatatcagcaatgaaatcagca
gatatctttccttttctaaaagaaaaagcaaaagaacctttccagttggatgctggtccg
ttatggcgcacacacctttttcatcggttagaagaatgcattgttcttataacaattcac
catatcatatttgatggtgtgtcgatgctgacattgatatcggcgctattcgaagcgtat
caacaattgctgaatgggattgaacccttgcagcagccatcaacagctgattattacgat
tttgtcgattgggaaaatcgaatgctgactggcagagaaggggaagagcatctcgcttac
tggaaagaacagttgtctgggagtctgccagttcttgatttgcctgctgaccgtccgcgg
tcttcagcacgaaaatttaaggggcaagcttataaaagcttgctccctcatcacctgaga
aatcaaattaaatcgtttgcccgcaccaatcatgtgaatgaatcggttgtgtttctctcc
atttacaaagtactgctgcatcattatacaaaacaaaaggatatcattgttggcgttccg
acaatgggtcggcaagaagacagatttgaaaccctaatcggttattttatcaatatgatg
gctgttcggagcaagaatatcggatctcagccattaacagcatttatttgggaactgcag
ctgacagtggctgacggcctggatcatgcggcgtttccgttccctgcattggtaagagag
ctgaatgtagaccgctcggccgcggattctccggtttttcaaacagcttttctgtaccaa
aacttttttcaggcaacaggcttgcaaaaagtgcttgaaccgtatcaaacgcttggcatc
gaatatattgaagacattcggcaagagggtgaatttgagctggcgctcgaaatatatgag
caagaaaatgaaacagtgcttcatcttctgtacaaccctgatttgtacgaactgtcctcc
attgaaagcatgatggagaactatatgaagctcgcgcagcacatgatggaggacccgtct
ttgccgcttgaagcctactctttgcaattaaatcaagaacaaactagtttgctggaacaa
tggaatgcgacagggacaaacatcgcaaatgacaagtgtatacatgaggtgtttgaggaa
aaagcgaaacaaacccccgatgcggttgctgtgatgtttgaagacagatcacttacatat
aaagaagtagatgaaaaaagcacatctgttgcagtctaccttcaacatcagggtgttgga
cctgaacagcccgttggcatttgtgcagagcgttcgtttgatatgatcatcggaatttta
ggaatactgaaagctggcggagcgtatgtgccgttagatccaagttttccgcaagaacga
ttagagtacatgctcaaagacagtcaggcatccattgtcctcacccaacctaacgttcat
gataggatcagcggattaactggcagccatgtaaaagcgatcaatatcgagttagcttgc
cgaaacgattatacagaccagcaaagcagcggtttaaagcgggaagtaaaaccggaacac
ctcgcttatattatttatacatcgggaagcactggagagcctaaaggggttatggtagag
catcggagcattatgaataccctgaattttcttgaatctcactatcctgtaacggctgag
gatgcatatttattgaagacgaactatgtgtttgatgtatcgatctcagaattattcgga
tggtttattggagacggccgtcttgtgattcttccgcctaatggggagaaatcaccgcag
ctttgcatggattatattgaaacatataaagtgactcacattaattttgtgccggccatg
ctgcatgtttttttagaaatggcgaaagacaacaagcgattcacagaggatggtccgctg
aagtatatgatggttgcaggtgaagccttccctaaagaattagtgaaaaaggcggtatca
ctctttacaaactgccgtgttgaaaatatatacggaccgacggaagcctccatttacgct
gcgtatttcggatgcggaaaaggagatatcgcaagtcaccatacaccgattggaaagcct
gtctccaacacgaaaatttatattgtggaccagcatttaaagcctgtcccgatcggaaag
cctggtgagctatgcatcgctggagccggcttagcaagaggctactttaaaaagccgggg
cttacggctgaaaaatttattgataatccctttgaaccagggacgaagctatataaatcg
ggtgattcagcaaggtggcttcctgacggcaacatagaatacttgggacggattgacagc
caagtcaaaatacgcggttttcgcgtcgagctgggcgcaatagaaacaaagctgagtgaa
tttccgggcattttagatcaggccgtagtggtgaagcagctggaaggccatcaacagctc
gctgcttattatacagaggaaagcggacatgcctctgccaatccaaaagatttgcgcctt
catctaaaatcgagtctgcccgaatatatgataccttcacactttatccgcttagatgag
cttccattatcgcccagcggaaaagtgaaccgtaaagaattagaaaaacgcgagatcgtg
ttcaacagaaggaaaccaaatcacttgcaattaacggaaatagaggatcaggtgctgcgt
atttgggaggaaacgctcaaggtcagcggatttgggccggaagacggatttttcgatgcg
ggcggcgattcgcttctggctgtagctgtggctgaacgaatcaaaaaagaattcgattgt
gagtttcatgttactgagctgtttgagttttccacgatccgtgcaatcagtgaatatatt
ttggagatgaaaaactcagatctagccgggacacaaaatgaagatcattatgatatcaaa
aaagatagaaaacacctagaacagaagattcccccttattttgatgacagtgttgcgatt
gtggggatatcttgccagttcccgggtgcgaaaaatcatcatgacttctggaaccacatc
aaagaaggcaaagaaagcatacgattcttttctgaagaagagcttcgcgcaaatggagtt
cccgaagaattgatacagcatcctgactatgtgcctgtgcaatctgtgatcgaagggaaa
gacttattcgatcccggtttctttcaaatctcgccaaaagatgctgagtatatggaccct
cagctccgcctcttattgctgcactcctggaaagcgattgaagatgcaggatatgtggct
aaggagattccggcaacaagtgtatatatgtctgcaagcagcaattcatatagaacgtta
ttgccgaaggagacaacagaaggacatgaatcaccggatggctatgtctcatgggtttta
gcccaaagcggaaccattcccacaatgatctcacataagctcggattaaaagggccaagc
tattttgttcattctaactgttcttcatcactagtcggtttatatcaagcatacaaaagc
ctgacatcgggcgaatcacaatatgcgcttgtcggaggcgcaacattgcacgcacaatca
gcgatcggctacgtgcaccaaaacgggttgaatttttcaagcgacgggcatgtaaaggcg
ttcgatgcttcggcggacggaatggccgggggcgaaggcgtagcggtcatcctgctgaaa
aaagctgtggatgccgtaaaagacggagaccatatttatgcgattatgcgcggaataggc
atcaataatgatggggcagaaaaagccggcttctatgcgccaagtgtaaaaggccaaaca
gaggtgatacagcatgtattggatacaaccaaggttcatcctgaaacggtcagttatatt
gaagcgcacgggacgggaacgaaattaggcgatcctattgaaatgtctgcgctaaataaa
gtgtacaagcaatacacagacaaaacacaattttgcggaattggttcagtgaaaacgaat
attggccatttggatacagctgcggggttagccggatgtattaaagttgcgatgagttta
taccataatgaacttgcaccgaccatcaactgtacggagccgaatccggatataaagttt
gaaagctctcctttttatgttgtccgtgaacgaaaatcgttagagaaacacgcaggtgtc
catcgggcggctctgagctcattcggccttggcggaactaacgcccatgcaatatttgag
caatatgaaaacatttctgatgcaggtaccgaaaacgaaggcaatcagccttacatcatt
cctatatcagcaaaaaatagtgaacggctccaagtatacgcgaaggaaatgctgtcctat
atcagtcaagacgagcaaaggcatttctctttaagagatattgcatataccttccaagtc
ggccgtgaagcaatggataacaggatcgtttttatagtgaacgatctggaagaatggaaa
catcagctggaagcttttgtgactggaaagccgctcgcagaaggctgtattcaaggagaa
aaaacgagaatgacatccgctgaacagctgcttggaaatgctgaagcagatgatatggct
tcatcgcggatatcaaaagaagaattgagaaagcttgccgagatgtgggcaaatggcttt
cacgttgaatggcgcaggctctatccaaatataaagccacgccgcatcagcttgccgaca
tacccttttgccgaagaacgatactggcctgaaagcagcaccggcgctatcacaacaatt
gaaccatctcgtttgcatcctttggtgcaccataatacatcggttctgtcagagcagcgt
ttcagctccattttcacaggacaagagtattttattgccgagcatatcattaaaggcatg
gcgattttgccggcggcggtcacgcttgaaatggcaagagccgctatagaacaaggaatt
ggcggattggaggatcatgaaactggaatcaggctgaaaaatgtcgtgtgggttcgcccg
gttgtagcaggaagtgagccggttcaggtaaatatcggactttacgatgaagatggcgga
cactttccttaccggatgtatggcgagccggaatccgctgatgcagaaccagttgtatat
aaccaaggtatagcggaattgattcagttaaagcgagaaaaagcactggatctttctaag
atcaagaaacaatgtgatcaaagcagaatggatgctgcctcgttttatgaagggatgatc
ggcgccgattacggtccaggttacaagagtgtagaggccgtatataaaggcgacggccag
ctgcttgcaaaattatcactgccggaatctgttgcacatacgttgggcgattatgttctt
catccaagtgtaatggacggggcgttacaggcggctgaatatttgcaaaatgtcgtcaga
gcggaactttcagacactgaagactttaaggcagcactgccatttgccctggaggaactt
gaggtctttcgtcagtgcgtttctgacatgtgggtttatgttcaattcaactcgaaaaac
aaaccaggagatttgatacagaaagtcgatattcacctatgtgatgagcatggcatgatc
tgcgtgcggctgaaaggattttcgacgagagtgatggaggcagatatacaaaccgaacca
tcaaaaatcaacgctgaaactttattgcttcagcccgtttggcaagaacaaaaggctgct
gacagcttagctgcaaaaaaatatgcagagcatctcgtattcctatgtgaatatgatcat
gagacgagaaaacaaattgaagcagctatcgaggatgtccatgtatacagcctggaagca
aggccttcttcagtagatgggcgtttccattcttatacagaacaagtgtttaaaaaggta
caagagatcattcgtacgaaaccgaaagacggcattctcgttcagatcgtaacctctgca
gagggagaacagcaattgttttcaggattgacaggactgctgaaaacagcttgtcaggaa
aatgccaaactaaccggccaaatgattgaagtcagcagtgaagaaagtggagaaagcatt
actggcaaactgttagaaaatcaaatgagcagcgattcatatgtcaaatatcaaaacggg
acacggtatattgctgattggcgtgaaatcaaacaggcaaaaggagacgccagcaaaccg
tggaaagacaatggcgtttatctcattacaggaggtgccggcggactaggtcatattttt
gcaaaggaaattgcggaacaaatgaaaaatgcgacagtcattctggcgggccgctcacct
cttagcgaaagcaaaagcaaaaagctgaaagagcttcatagcaagggggctgacatcacc
taccggcaaacagatgttaccaataaaattgaagtctatcagctcattgacgacattcaa
aaaagatatggccgtctgaacggtattcttcatagtgccggaatcatcaaggacagctac
atggttaataaacaggcaaaagatctgcacgatgtactggcgcctaaagtaaaagggctt
gtttatctagacgaagcgagcaaggatttgcctttagacttctttgttctcttttcatct
ctttcaggaagtttggggagcattggccagtctgactatgcggcagccaatgtatttatg
gatatgtatgcaggctatcgaaataggcttgccggcctcagccagcggcatgggaagacg
ctttctgtaaactggcctttatggagagatggaggcatgcaggttgatcaagaaactgag
aaaaggcttgtgcaacttgccggtattgttcctatgagggcggaaaaaggaattcaggca
ttatatcaagcacttcattcagaggcaaaccaagtaatggtgatcgaaggcgatgtgcag
aaaataaaacaaaacatgctggccaaaaatgcctcagcacctatggaaaagaaggaagca
gaacacatgactgaacaaataaatagcattgatacagacagtttgctggataaagtaaag
gcgatgttaaagcgagagatcgccaagctgttaaaggtcaagcttgaaacgattgacgat
catgcagagatgacggtgtatggttttgattctatctccatgactgaattcaccaaccat
atcaatcgcgcctatcagttagagctgacgccaaccgtattttttgaccacccgacgatt
catgcgtttggcaagcatttgtcagaagaatatcaatcggtatttgcgaagacatttgct
gtgcgcgctgtatcggctcagcttcagcctgctgcgaaacaggaacaagccgtgcgtgcc
aaagctaaaagacgcagaaagcagcaagtcatgctgccaaacgccatacagagtgatgct
gggcctgagccaattgccattgtgggcataagcgggattttccctatggcgaaagacgtt
gaggcgtactggaacatcttaaaagagggcaaagactgcatgacggaaatcccgaaagat
cgctgggattggcgtgaatatgaaggtgatccggcgaaggaagtcaataaaacgaacgtg
aaatggggcggttttattgacggtattgcagattttgatccattattctttggcatttcc
ccgcgtgaagctgaacaaatggaacctcagcagcgcttactgctgacttacgcctggaaa
gcgatcgaagatgcaggatattcggcgaaaaggttgtcaggcacaaaaaccggcgtcttc
atcggaacgggaaatacaggatacagctctcttctatctaaagcgaactcggcaatagaa
ggatcagcggcagccaatacgagcccatcggtcggtccgaaccgggtcagttatttcctt
aatctgcatgggccgagcgaaccggttgatacagcgtgctcaagttcactagtggcgatc
caccatgccatctcttcaattgaggaaggcacttgtgacatggcattagccggcggtgta
aatacgattatccttcctgaggtgtatatcagctttgataaggcgggagcactgagcaaa
gaaggaaaatgcaagacgttttcaaatcaagccgatggttttgcacatggggaaggtgcc
ggcatactgttcctgaaaaaattaaaagcggctgaagaagcgggagaccatatttacgga
gtcataaaaggcagtgcaatcaatcacggcggccgtgcagcctctttaacgactcccaat
ccgaaggcgcaggcagatgttattcagtcggcatatcaaaaagcgggaatcgacccgaaa
accgtgacctacattgaagcccacggaaccggaacggagcttggagacccggttgaaatt
aacggtttgaaatcagcttttaaagcattgggtgtaaatgaaggagacacatcagccaat
ccttactgcggattagggtctgtaaagacaaacatcggccacttatcgctggcagccggt
gcagcaggagttattaaaatattattgcagcttaagcataaaaccttagtgaaaagtctg
cattgcgaaaacgtgaatccatacattcagctgaaaaacagtccgttctatatcgtacgg
gaaacggaagaatggaaagcgctgaaaaatgaacagggagaagagcttcctcgacgggca
ggtgtcagttcatttggaatcggcggagtaaacgcccacgtgattatcgaggaatatatt
ccggaagcatccgatgagaatataccatccatcgcgccggaacatccgggtatcttcgtt
ttatcggctaaaaatgaagcgcggctaaaagaacatgcacagcagctggcagatgcgctt
gataagcaaacatatagtgacgtaaatctcgcccgaatcgcttatacactgcaagccgga
cgggatgcgatggaagaacgtctcgggattatttccggttccattgaggatttacagaaa
aagttaaaagactttgcagcggagaaaagcggtgtggaggatgtatttaaaggcaggatt
gataaaggcacactccaaatgctgacagaggacgaagagattcaagaagccgtcgagaaa
tggatggaacggggaaagtatgcaaaattgcttgaattatgggtaaaagggcttgatgta
gactggacgaaattgtatggcgagaatctgccaaagcgcatcagcttgccgacgtatcct
ttcgcaaaagaccgttattggatctctgatcatattgaaaaaagcggcagcattgatgca
aatcaagcagcctcccgccttggcggagccgtgctgcatccattaatgcatcaaaacaca
tccaatctctcggaacaaaggtttagctctatttatacgggagaagagtttttccttgct
gatcatgttgtgaaaggccaacggattttgccgggagtggctcatcttgaattggcgcgg
gcagctgttgagcaggccgcagaggtacaaggtgtaccgcgcatcatgaagctaaagaat
gcggtgtgggtgcggcctattgttgtagaggatcagccgcagcaagtacacattaggctt
ttaccgggagaaaatggtgagatctcttatgaaatctatggtcattcagacgttactggc
gaacagtcaatcgtctacagtcaaggcagcgcggtattgaatcctgctgaaaatttgccg
gcggttgatttgcaatctctgcgggagcagtgtcaggaaagtcatttcagcgtaaacgaa
gtatacgacacctatcgaatgattggatttgaatatggtcctgcttatcgcggagtgaaa
aaaatctatacagctgaacaatttgttttggcaaaattgtcattgcatccgtcagctgca
gatacgctcagccaatacaaaatgcaccctgggctgatggattctgctttgcaggcgtca
agcattttgacaggagccggggataaccagctgacactgccttttgcggtccaggagctt
gaagtcttcggagcatgttcgtcagaaatgtgggtatacgcaagatacagccaaggcagc
aaggcaactgataaggtgcaaaagcgcgatatggatattttagatgagagcggcaatgtt
tgcgtacggatgaaaggattatctttcagagcagcagaaggcggctctggatcggcggaa
tctgatcaaacgctggcaaccctgatgtttgaagaaaaatgggtgcccaaggattttaaa
aaagaaagtcctgagcctcattacgaacggcacattgtcatgctttgcgacatgaatggc
ctctcaaaagatcgcattgaatcaagaatgacaggagcggaatgcatcgttttggagtca
ttccgcgaaggacttgcagagaggttccaagattatgccgaacaagcgcttgagacggtc
cagggtcttctcaaaagcagacctcagggcaatgttctgatccagctgcttacctctgca
caaagaaagcagtactcattctcagggctatcggcgctccttaaaaccgccggcctggag
aataaaaaactaatcggccagacgattgaaatcgattcacatgaaaatgttgaaagtgta
atagaaaaactgaaagagaataaaaggcacacagaagatcagcacatcaaatatgaaaaa
ggcaaacggtacatcaatgatctggatgaaatgcaaatagatgatcgggaaataagcatg
ccgtggagagataaaggtgtatacctcatcacgggcggcgcaggaggacttgggtttatt
tttgcaaaagagattgctcgccaagccgaacagcctgtgctcattctgacaggcagatcc
gcgttgaatgcggatcagcaggcggagcttaacgaacttcagcaattaggggctcgcgca
gaatacaggcaggttgacgtgacacaaacggaagcagcctccgagcttatcacaagcatt
acgtctgattacgaagacttgaatggtgtcattcacagcgctgggctgattaaagataac
tatcttatgagcaaaaccaatgaagagctgacacaagttctcgctcctaaggtgaaaggg
cttgtgaatgtggatgaggcaaccgagcatcttgcgttagatttctttatcctcttttct
tcaatatcaagtgttgccggcagcgcgggacaggccgattatgcaatggctaatgcattt
atggacagttatgcagcttatcgaaatgcgcttgtaaccgccatgtacaggcacggacaa
acgttgtcaatcaattggccgctctggaaagaaggcggcatgcgcgcgaataaagaaatt
gaaaacatgacgttgaaaaacacaggtgtgactccaatgcggaccgagaccggcattcaa
gcgctgtataaagctttggcatttggcaaagatcaagtcatcgtcatggaaggaatcaaa
gacatgatgagggaaaagctgactcaaaagccgtcttctgatgatgtaccaatgaaaaca
gtgcaagtaccggtgacatctgaagcaagaatggatcaaggaaatatgtgcgaccacatt
caagaagttttaaagcaaacaatctctcaattgctcaaaatcaaacctgaagagattgac
ccggacatggagtttaatcaatatggatttgattcgattacgttaactgaattcgcaaat
acactgaatgagaagtacaagctggatcttacgcctacgatcttctttgagcacgcaact
gtttatgcatttgcagggtatctgtcagaagaatatccaaatgcttttacagctcaaacg
cctgccaaagctggggtgctaatgcagcctgtcgaacagaatataaaaaatatgacgttt
tcgactgaaaaccgctttgtaaaaccttcggtaacaccaatgcaaaaggaagctgatccc
aagcctgagcctattgcgattgtgggaatgagcggcgttttcccaaaggcaaaagacgtt
gaggaatattggaagaacctgtcatcgggcacagattgtattacagaggttccaaaagac
cgctgggattggcaggagtattacggagaccctctgaaagaagcgaataaaacaaacgtc
aaatggggcggttttattgatgaagtagctgactttgatccattgttcttcggcatatct
ccgctggaggctgagcagatggagcctcagcagcgcctgttaatgacctatgcgtggaag
gcggtagaagaagcgggacactcagcgagaagcctggcaggaaccaaaacgggcatcttc
atcgggacaggaaacacagggtacagttcacttctgtcaaatgtagacatcgaaggctca
gcggctgcgaatatgagtccttctgcaggaccgaatagagtcagttatttcctgaacatt
catggaccgagtgaaccgatcgacactgcgtgctcaagctctttggtcgccattcatcat
gcggtttgcgccattgaaaatggaaactgtgaaatggcgattgcgggaggggtcaacacg
gtcgtaactccgcaaggccatatcgcctatgataaagccggggcgctgagcaaagaagga
agatgcaaaacattttctgacaaagccgatggattcgcagtcagtgaaggtgccggcatt
ctctttctgaaaaagctgacagcggctgaacgagacggtgatcatatttacggtgtcatt
aaaggaagtgcggtaaaccacggtggccgcgcaaattctctaacgactcctaatccgaaa
gctcaggcggatgtcgtaaaaacagcatatgaaaaagcgggaattgatccaagaaccgta
acttatattgaagcgcatgggactggaaccaagctgggcgatccagtagaaatcaacggc
ttaaaagcggcatttaaagagctgtatgaaaaaacgggggacccggctgttcatggcagc
cattgcggacttggatcagcgaaaacaaacatcggtcacttatcactggcggccggtgtg
gcgggtgtcattaaagtgttattgcagctcaagcataaaacgcttgtcaaaagtctgtac
agtgaaactgttaatccatatatcaaactggatgacagcccgttttatattgtgcaggaa
tcgagagagtggcaggcgcttcgggatgaagccggccgagagctgccgcgccgcgcaggc
atcagttcgttcgggataggcggcgtcaatgcccacgtggtcattgaggaatatattccg
aaagaaacaacccatcctgcaacagcaccagctgtgacagcacagcacccgggcatcttt
attttgtcggcaaaggatgaagatcgtctgaaagaccaagcccggcaattagcagacttt
atcagcaagcgatctatcactgctcgtgacctcactgatattgcttatacactccaagag
gggcgtgatgcaatggaggagagattagggattatcgctgtctcgactggggacttgctg
gaaaaactgaacctctttatagaagggggcaccaatgcgaagtacatgtacagaggcaga
gcagaaaaaggtatcgcacaaacattgagatcagatgacgaagtacagaaaacgctcaac
aatagctgggagcctcacatatatgaaagacttcttgatttatgggtaaaaggcatggaa
ataggctggagcaaactgtatgacggcaaacagccgaaacgcatcagcctccctacctat
ccatttgcgaaagaacgctactggataacggatacgaaagaggaggcagccgcccatcaa
acagctttaaaaacagtcgaatcagcagctttgcatccattgatacatgtcaacacatct
gatttgtcagagcagcgtttcagctcggcctttacaggtgctgagttctttttcgccgat
cataaggtgaagggaaaaccggttatgccgggcgtggcatatcttgagatggttcatgct
gccgttataagagcagtgagaagaaccgaagatcaacaatctgttattcacatcaaaaat
gttgtgtgggtgcagccgattgtggcggacggccagcctgttcaagtggatatcagtcta
aatccccagcaggacggcgagattgcttttaacgtctatacagaggctgcacacaatgat
cgaaagatacattgtcaaggcagtgcttcaatccgcggggcaggagacattccggtccag
gatatcagcgtgcttcaagaccaatgcagtttaagcacactctcacacgaccaatgttat
gaattgtttaaggcgatcggcattgactacggacctggttttcaagggatagatcggctt
tacatcggccgcaatcaagccttggcagagctttctctgcctgctggtgtaactcacaca
ctgaatgaattcgttcttcatccaagtatggccgattctgctttacaagcgtcgatcggg
ctaaagctgaattccggtgacgagcagctttctctgccttttgcgctgcaagagctagaa
atattcagcccgtgtacaaataaaatgtgggtgtctgtgacatctcgtcctaatgaggac
aaaatacagagactggatattgatttgtgtgatgaacaaggccgagtgtgtgtaagaatc
aaggggattacctcaaggctgctggaagaaggcatacaaccgccagacgggccgacatca
ctaggaaactccaaagcaactcttaacggagcgcttcttatggcgccgatatgggatcga
gtgcagctggagaagaggatcatttcgcctgctgatgagcgtgttgtcatcctcggaggg
gatgacaacagcagaaaagctgttcaaaggcagatcccatttgccaaggagctgtacatt
gagccgaacgcatcaattcatagaattgcaggacagcttgaagcactcggatcgtttgac
cacatcgtgtggatgtctccttctcgtgtgacagagtgcgaagtcggcgatgaaatgatt
gaagcccaagatcaagacgtcattcaaatgtataggctcattaaggcaatgctttcttta
ggctatggacagaaggagataagctggacggtcgtgacggtgaacacacaatatgttgat
cagcatgatattgtcgatccggtcgatgccggggtgcacggcctgatcggttcaatgtca
aaagaatatccaaattggcagacaaagctgatcgatgttaaaaaatacgaagacctgccg
ttatctcaactcctttccttgcctgccgatcaagaagggaatacgtgggcctatcgagac
aaggtctggcataagcttcgtttgattccagtacacaacaatcaaccggtgcacacgaag
tataagcacggaggtgtttatgttgtcataggcggagctggcggtattggtgaggcgtgg
agtgaatatatgatcagaacatatcaggcgcagatcgtttggattggcagaaggaaaaag
gatgcagccattcaaagcaagctggacagacttgcacgtctagggccagccccgtattac
attcaagcagatgcggctaaccgagaggaattagaacgcgcgtatgaaacaatgaaacaa
acgcatcatgaaatcaacggcatcatccattctgcgattgtcttacaagaccgaagcctg
atgaatatgagtgaggaatgtttcagaaacgttcttgctgcaaaggttgatgtaagcgtg
cgaatggcccaagttttccggcatgaaccactggattttgttttgtttttctcttccgta
caatcgtttgcaagagcttccggacaaagcaattacgctgcgggctgcagttttaaggat
gcttttgcacagcggctgtctcaagtatggccttgtacagtagccgtgatgaattggagt
tattggggaagcattggtgttgtttcatcaccggattaccaaaagagaatggctcaggca
ggcataggctcaattgaagcccctgaagcaatggaagctttggaattgctgctcggggga
ccgctgaagcagctagtaatgatgaaaatggcaaacgaaacgaatgatgaagcggaacag
acagaagaaacgattgaagtgtacccggaaactcacggctccgccatgcaaaagctgcga
agctatcacccgggtgacagcacaaagattcaacaactgttatag

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