Bacillus subtilis subsp. subtilis AG1839: BSUB_03015
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Entry
BSUB_03015 CDS
T03442
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bsut
Bacillus subtilis subsp. subtilis AG1839
Pathway
bsut00290
Valine, leucine and isoleucine biosynthesis
bsut00620
Pyruvate metabolism
bsut01100
Metabolic pathways
bsut01110
Biosynthesis of secondary metabolites
bsut01210
2-Oxocarboxylic acid metabolism
bsut01230
Biosynthesis of amino acids
Module
bsut_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bsut00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BSUB_03015 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BSUB_03015 (leuA)
Enzymes [BR:
bsut01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BSUB_03015 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Retrotran_gag_2
Motif
Other DBs
NCBI-ProteinID:
AIC45523
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All DBs
Position
complement(2864904..2866460)
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AA seq
518 aa
AA seq
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MRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEAGFPASSRGDFLAVQEI
ARTIKNCSVTGLARCVKGDIDAAWEALKDGAQPRIHVFIATSDIHLKHKLKMTREQVIER
AVGMVKYAKERFPIVQWSAEDACRTELPFLAEIVEKVIDAGASVINLPDTVGYLAPAEYG
NIFKYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIENGADQIECAVNGIGERAGNAAL
EEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLTGMAVPRNKAVVGDNAFAHESGIHQ
DGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRLTALGFQFDSEEINKFFTMFK
ELTEKKKEITDEDLVSLILEEKVTDRKIGYEFLSLQVHYGTSQVPTATLSLKNQENAQLI
QEAATGAGSVEAIYNTLERCIDKDVELLDYRIQSNRKGEDAFAQVYVRVLVNGKESAGRG
IAQDVLEASAKAYLNAVNRQLVFQSNMSGLKNHTAVGS
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgcgcaaaattaattttttcgatacgacgcttcgtgatggtgaacagtcccctggagtg
aacttgaatacacaggagaaacttgccatagctaagcagctcgaaagactcggggcagac
atcattgaagcgggatttcccgcttcgtcccgaggtgactttttagctgttcaggaaatc
gcaagaaccattaaaaattgttcagtaactggtctggcccgttgtgtaaaaggtgatatt
gatgctgcttgggaagcgttaaaggatggcgctcaaccaagaattcatgtatttatcgcg
acatcggacattcatttgaagcacaagctgaaaatgacacgtgaacaagtcattgaaaga
gcagttggaatggtgaaatacgcaaaagaacgttttccgattgtgcaatggtcagctgaa
gatgcctgccgcactgaactgccgtttctagcagaaatcgtcgagaaagtgattgacgca
ggcgccagtgttatcaatcttccggacactgtcggctacctggccccggcggaatacgga
aatatctttaaatatatgaaagaaaacgttccgaacattcacaaagcaaagctttcagcc
cactgtcatgatgatttgggaatggcagtcgcaaactctcttgctgcgattgaaaatggc
gctgatcaaatcgaatgcgctgtgaacgggatcggtgaaagagccggaaacgcggcatta
gaggaaattgccgtagccctccataccagaaaagatttctaccaagtcgaaacaggtatt
acgctgaacgagattaagagaacaagtgatttagtaagcaaactgacaggcatggctgtc
ccgcgcaacaaagcggttgttggagataatgcatttgctcatgaatcaggcatccatcag
gacggctttttaaaggaaaaatcgacttatgaaattatttcaccggagcttgtcggcgta
accgcagatgcgcttgtcctaggtaaacattccggacgccacgcatttaaagaccggctg
actgctttaggattccaatttgacagtgaagagattaataaattctttacgatgttcaaa
gagttgactgagaagaaaaaagaaatcactgatgaggatcttgtttctcttattttagaa
gaaaaagtaacagatcgcaagattgggtatgaatttctttctctgcaagtacattacgga
acaagtcaggtccctacggctactctatctttgaaaaatcaagaaaacgcacagcttatt
caggaagctgcaactggagctggaagcgtggaagcaatctacaatacgcttgagcgctgc
atcgataaggatgtggagctcttagactaccgcattcagtctaatagaaaaggcgaagat
gcatttgcccaggtgtatgtaagagttttggtgaacggaaaagaatcagcagggcggggc
atagcgcaagacgtattagaagcatcagcgaaagcctatttgaacgcagtaaaccgtcaa
ttggttttccagtcgaatatgagcggattgaaaaaccacacagctgtcggatcataa
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