Bos taurus (cow): 100138040 Help Entry 100138040         CDS       T01008                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism bta  Bos taurus (cow) Pathway bta01521   EGFR tyrosine kinase inhibitor resistance bta01522   Endocrine resistance bta04010   MAPK signaling pathway bta04012   ErbB signaling pathway bta04014   Ras signaling pathway bta04062   Chemokine signaling pathway bta04068   FoxO signaling pathway bta04072   Phospholipase D signaling pathway bta04150   mTOR signaling pathway bta04151   PI3K-Akt signaling pathway bta04510   Focal adhesion bta04540   Gap junction bta04630   JAK-STAT signaling pathway bta04650   Natural killer cell mediated cytotoxicity bta04660   T cell receptor signaling pathway bta04662   B cell receptor signaling pathway bta04664   Fc epsilon RI signaling pathway bta04714   Thermogenesis bta04722   Neurotrophin signaling pathway bta04810   Regulation of actin cytoskeleton bta04910   Insulin signaling pathway bta04912   GnRH signaling pathway bta04915   Estrogen signaling pathway bta04917   Prolactin signaling pathway bta04926   Relaxin signaling pathway bta04935   Growth hormone synthesis, secretion and action bta05034   Alcoholism bta05160   Hepatitis C bta05161   Hepatitis B bta05163   Human cytomegalovirus infection bta05165   Human papillomavirus infection bta05200   Pathways in cancer bta05205   Proteoglycans in cancer bta05206   MicroRNAs in cancer bta05207   Chemical carcinogenesis - receptor activation bta05208   Chemical carcinogenesis - reactive oxygen species bta05210   Colorectal cancer bta05211   Renal cell carcinoma bta05213   Endometrial cancer bta05214   Glioma bta05215   Prostate cancer bta05220   Chronic myeloid leukemia bta05221   Acute myeloid leukemia bta05223   Non-small cell lung cancer bta05224   Breast cancer bta05225   Hepatocellular carcinoma bta05226   Gastric cancer bta05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100138040 (SOS2)    04012 ErbB signaling pathway     100138040 (SOS2)    04014 Ras signaling pathway     100138040 (SOS2)    04630 JAK-STAT signaling pathway     100138040 (SOS2)    04068 FoxO signaling pathway     100138040 (SOS2)    04072 Phospholipase D signaling pathway     100138040 (SOS2)    04151 PI3K-Akt signaling pathway     100138040 (SOS2)    04150 mTOR signaling pathway     100138040 (SOS2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100138040 (SOS2)    04540 Gap junction     100138040 (SOS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100138040 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100138040 (SOS2)    04660 T cell receptor signaling pathway     100138040 (SOS2)    04662 B cell receptor signaling pathway     100138040 (SOS2)    04664 Fc epsilon RI signaling pathway     100138040 (SOS2)    04062 Chemokine signaling pathway     100138040 (SOS2)   09152 Endocrine system    04910 Insulin signaling pathway     100138040 (SOS2)    04912 GnRH signaling pathway     100138040 (SOS2)    04915 Estrogen signaling pathway     100138040 (SOS2)    04917 Prolactin signaling pathway     100138040 (SOS2)    04926 Relaxin signaling pathway     100138040 (SOS2)    04935 Growth hormone synthesis, secretion and action     100138040 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     100138040 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     100138040 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100138040 (SOS2)    05206 MicroRNAs in cancer     100138040 (SOS2)    05205 Proteoglycans in cancer     100138040 (SOS2)    05207 Chemical carcinogenesis - receptor activation     100138040 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     100138040 (SOS2)    05231 Choline metabolism in cancer     100138040 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     100138040 (SOS2)    05225 Hepatocellular carcinoma     100138040 (SOS2)    05226 Gastric cancer     100138040 (SOS2)    05214 Glioma     100138040 (SOS2)    05221 Acute myeloid leukemia     100138040 (SOS2)    05220 Chronic myeloid leukemia     100138040 (SOS2)    05211 Renal cell carcinoma     100138040 (SOS2)    05215 Prostate cancer     100138040 (SOS2)    05213 Endometrial cancer     100138040 (SOS2)    05224 Breast cancer     100138040 (SOS2)    05223 Non-small cell lung cancer     100138040 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     100138040 (SOS2)    05160 Hepatitis C     100138040 (SOS2)    05163 Human cytomegalovirus infection     100138040 (SOS2)    05165 Human papillomavirus infection     100138040 (SOS2)   09165 Substance dependence    05034 Alcoholism     100138040 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100138040 (SOS2)    01522 Endocrine resistance     100138040 (SOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH RHG20_PH PH_19 Motif Other DBs NCBI-GeneID:  100138040 NCBI-ProteinID:  XP_024853748 BGD-bta:  BT15508 Ensembl:  ENSBTAG00000005550 VGNC:  54490 UniProt:  F1N1J9 LinkDB All DBs Position 10:complement(43052603..43158246) Genome browser AA seq 1332 aa AA seqDB search MQQAPQPYEFYSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPKFNENFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKI RSEEHEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG CSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIYAAKSAEEKNNWMAALI SLQYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA LEKGEQPISTDLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLESFISSVR GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA ENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGCASEKEFTDYLFNKSLEIEPRNCK QPPRFPRKSAFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS EEPLIPPPLPPRKKFDQDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPAPAGPFDGPL HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHLHRDPDWFRDVSTCPNSPN TPPSTPSPRVPRRCYVLSSSQNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPVY RLPLLENAETPQ NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccttacgagttctacagcgaagagaacagtccgaaatggcgg ggactgttggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct aatgaagagtctctctattacattgaagagctgatttttcagctgcttaataaattatgc atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaaagaaga aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaagttttagggtac aaagtggactaccatgtatccctgtatattgtggctgtgctggagtatatctcagctgat attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcaacaa gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac ataggcttggtttctctttgtgaagatgaacctagttcttcaggcgaattaaactactat gaccttgttagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc ataaaagtgtttcgagaagcttttctttctgacagaaagctgtttaaaccttctgatatt gaaaagattttcagtaacattttagatatacatgaattgactgtgaaacttttaggttta attgaagacacagttgaaatgactgatgaaagtagccctcatcccttagctggcagctgt tttgaagatctggcagaggagcaagcatttgatccttatgaaacattatcccaggatatt ctttcaccaaagtttaatgaaaattttagtaagttgatggccagacctgcagtggctcta cactttcagtccatcgctgatggttttaaagaggcagttcgttatgtccttccacgcctt atgctggtgccagtatatcattgttggcactattttgaattattaaagcaattgaaaata cgtagtgaagagcatgaagacagagaatgtttgaaccaagctattactgctctcatgaat ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat gaatttattatggaaggcccgttgacaagaattggtgctaaacatgaacggcatattttt ctctttgatggcttaatgattagctgcaaacccaatcacagccagtcacgccttccagga tgcagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt gataaagaagatacttgtgagtgcaaacatgcttttgaattagtatccaaagatgaaaac agcataatatatgctgctaagtctgccgaagagaaaaataattggatggcagcacttatt tcccttcagtatcgtagtactcttgatcgaatgctagattcagtattattgaaggaagaa aatgaacaaccattgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct gaggaaaacattgtttttgaagacaacttgcagagtagaagtggaatccccattattaaa ggaggaactgtggtgaaattaattgaaaggctaacatatcatatgtacgcagatcccaat tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattactaagc ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggcg ttagaaaaaggcgagcagcccatcagtacagaccttaaaaggtttcgcaaggaatacgtc caaccagtacaacttagggtcttaaatgtgtttcggcactgggttgaacaccatttttat gactttgaaagagacttggagctgcttgaaagactagaatccttcatttcaagtgtaaga gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaagaggaaaaaacaa gctcaggcaaatggtataagccataatattacctttgaaagtccacctccaccaattgaa tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata gaaattgcacgtcagctgacccttttggaatctgatctctacaggaaagttcaaccttct gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta aaaatgattcgccacaccacaaatctcaccctctggtttgaaaaatgcattgtggaggca gaaaattttgaggaacgagtggcaatactgagtagaattatagaaattctgcaagttttt caagatttgaataatttcaatggtgtattggagatcgtcagtgcagtaaattcagtatca gtctatagactagatcatacctttgaggcgttgcaggaaagaaaaaggaaaattttggat gacgctgtggaattaagtcaagatcattttaaaaaatatctagtgaaacttaagtcaatc aatccaccctgtgtgcctttttttggaatatatttaacaaatatactgaagactgaagaa gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg aaagtagctgaaattactggagaaattcagcagtatcaaaatcaaccttactgtttacgg atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggatgtgcttctgaa aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaattgcaaa cagccacctcgatttcctaggaaatcagctttctccttaaaatctcctggaataaggcct aatacaggccgacatggctctacctcaggtactttgcgaggtcacccaacaccattagaa agagaaccgtgtaaaataagctttagtcggattgctgaaacggagcttgaatcaacagtg tcagcaccaacctctccaaatacaccatctaccccaccagtgtctgcttcttcagacctt agtgtgtttttagatgtggatctcaacagttcctgtggaagcaatagcatctttgctcca gtcctcttgcctcattcaaagtctttcttcagttcgtgtggtagtttacataagctaagt gaagagccactgattcctcctccacttccacctcgaaaaaaatttgatcaggatgcttca aattccaagggaactatgaaatctgatgatgacccccctgctattccaccaagacaacct cctcctccaaaggtaaaacccagagttcctgctcccgctggtccatttgacgggcctctg cacagtccacctccaccgccgccgagagaccctcttcctgatacccctccaccggttcca cttcggcctccagaacactttataaactgtccgtttacccttcagccacctccactggga catcttcacagagatccagactggttcagagacgttagtacgtgtccaaattctccgaac actcctcctagcacaccctctccaagggtacctcgtcgatgctatgtgctcagttctagt caaaataatcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct catctaccaaaactgccaccaaagacttacaaacgggagctttcacaccccccagtgtat agactgcctttgttagaaaatgcagaaactcctcaatga

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