KEGG   Bos taurus (cow): 100298939
Entry
100298939         CDS       T01008                                 
Symbol
HRAS
Name
(RefSeq) GTPase HRas isoform 1
  KO
K02833  GTPase HRas
Organism
bta  Bos taurus (cow)
Pathway
bta01521  EGFR tyrosine kinase inhibitor resistance
bta01522  Endocrine resistance
bta04010  MAPK signaling pathway
bta04012  ErbB signaling pathway
bta04014  Ras signaling pathway
bta04015  Rap1 signaling pathway
bta04062  Chemokine signaling pathway
bta04068  FoxO signaling pathway
bta04071  Sphingolipid signaling pathway
bta04072  Phospholipase D signaling pathway
bta04137  Mitophagy - animal
bta04140  Autophagy - animal
bta04144  Endocytosis
bta04150  mTOR signaling pathway
bta04151  PI3K-Akt signaling pathway
bta04210  Apoptosis
bta04211  Longevity regulating pathway
bta04213  Longevity regulating pathway - multiple species
bta04218  Cellular senescence
bta04360  Axon guidance
bta04370  VEGF signaling pathway
bta04371  Apelin signaling pathway
bta04510  Focal adhesion
bta04540  Gap junction
bta04550  Signaling pathways regulating pluripotency of stem cells
bta04625  C-type lectin receptor signaling pathway
bta04630  JAK-STAT signaling pathway
bta04650  Natural killer cell mediated cytotoxicity
bta04660  T cell receptor signaling pathway
bta04662  B cell receptor signaling pathway
bta04664  Fc epsilon RI signaling pathway
bta04714  Thermogenesis
bta04720  Long-term potentiation
bta04722  Neurotrophin signaling pathway
bta04725  Cholinergic synapse
bta04726  Serotonergic synapse
bta04730  Long-term depression
bta04810  Regulation of actin cytoskeleton
bta04910  Insulin signaling pathway
bta04912  GnRH signaling pathway
bta04915  Estrogen signaling pathway
bta04916  Melanogenesis
bta04917  Prolactin signaling pathway
bta04919  Thyroid hormone signaling pathway
bta04921  Oxytocin signaling pathway
bta04926  Relaxin signaling pathway
bta04929  GnRH secretion
bta04933  AGE-RAGE signaling pathway in diabetic complications
bta04935  Growth hormone synthesis, secretion and action
bta05010  Alzheimer disease
bta05022  Pathways of neurodegeneration - multiple diseases
bta05034  Alcoholism
bta05132  Salmonella infection
bta05160  Hepatitis C
bta05161  Hepatitis B
bta05163  Human cytomegalovirus infection
bta05165  Human papillomavirus infection
bta05166  Human T-cell leukemia virus 1 infection
bta05167  Kaposi sarcoma-associated herpesvirus infection
bta05170  Human immunodeficiency virus 1 infection
bta05200  Pathways in cancer
bta05203  Viral carcinogenesis
bta05205  Proteoglycans in cancer
bta05206  MicroRNAs in cancer
bta05207  Chemical carcinogenesis - receptor activation
bta05208  Chemical carcinogenesis - reactive oxygen species
bta05210  Colorectal cancer
bta05211  Renal cell carcinoma
bta05213  Endometrial cancer
bta05214  Glioma
bta05215  Prostate cancer
bta05216  Thyroid cancer
bta05218  Melanoma
bta05219  Bladder cancer
bta05220  Chronic myeloid leukemia
bta05221  Acute myeloid leukemia
bta05223  Non-small cell lung cancer
bta05224  Breast cancer
bta05225  Hepatocellular carcinoma
bta05226  Gastric cancer
bta05230  Central carbon metabolism in cancer
bta05231  Choline metabolism in cancer
bta05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
bta05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100298939 (HRAS)
   04012 ErbB signaling pathway
    100298939 (HRAS)
   04014 Ras signaling pathway
    100298939 (HRAS)
   04015 Rap1 signaling pathway
    100298939 (HRAS)
   04370 VEGF signaling pathway
    100298939 (HRAS)
   04371 Apelin signaling pathway
    100298939 (HRAS)
   04630 JAK-STAT signaling pathway
    100298939 (HRAS)
   04068 FoxO signaling pathway
    100298939 (HRAS)
   04072 Phospholipase D signaling pathway
    100298939 (HRAS)
   04071 Sphingolipid signaling pathway
    100298939 (HRAS)
   04151 PI3K-Akt signaling pathway
    100298939 (HRAS)
   04150 mTOR signaling pathway
    100298939 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100298939 (HRAS)
   04140 Autophagy - animal
    100298939 (HRAS)
   04137 Mitophagy - animal
    100298939 (HRAS)
  09143 Cell growth and death
   04210 Apoptosis
    100298939 (HRAS)
   04218 Cellular senescence
    100298939 (HRAS)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100298939 (HRAS)
   04540 Gap junction
    100298939 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    100298939 (HRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100298939 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100298939 (HRAS)
   04650 Natural killer cell mediated cytotoxicity
    100298939 (HRAS)
   04660 T cell receptor signaling pathway
    100298939 (HRAS)
   04662 B cell receptor signaling pathway
    100298939 (HRAS)
   04664 Fc epsilon RI signaling pathway
    100298939 (HRAS)
   04062 Chemokine signaling pathway
    100298939 (HRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100298939 (HRAS)
   04929 GnRH secretion
    100298939 (HRAS)
   04912 GnRH signaling pathway
    100298939 (HRAS)
   04915 Estrogen signaling pathway
    100298939 (HRAS)
   04917 Prolactin signaling pathway
    100298939 (HRAS)
   04921 Oxytocin signaling pathway
    100298939 (HRAS)
   04926 Relaxin signaling pathway
    100298939 (HRAS)
   04935 Growth hormone synthesis, secretion and action
    100298939 (HRAS)
   04919 Thyroid hormone signaling pathway
    100298939 (HRAS)
   04916 Melanogenesis
    100298939 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    100298939 (HRAS)
   04726 Serotonergic synapse
    100298939 (HRAS)
   04720 Long-term potentiation
    100298939 (HRAS)
   04730 Long-term depression
    100298939 (HRAS)
   04722 Neurotrophin signaling pathway
    100298939 (HRAS)
  09158 Development and regeneration
   04360 Axon guidance
    100298939 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    100298939 (HRAS)
   04213 Longevity regulating pathway - multiple species
    100298939 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    100298939 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100298939 (HRAS)
   05206 MicroRNAs in cancer
    100298939 (HRAS)
   05205 Proteoglycans in cancer
    100298939 (HRAS)
   05207 Chemical carcinogenesis - receptor activation
    100298939 (HRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    100298939 (HRAS)
   05203 Viral carcinogenesis
    100298939 (HRAS)
   05230 Central carbon metabolism in cancer
    100298939 (HRAS)
   05231 Choline metabolism in cancer
    100298939 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100298939 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100298939 (HRAS)
   05225 Hepatocellular carcinoma
    100298939 (HRAS)
   05226 Gastric cancer
    100298939 (HRAS)
   05214 Glioma
    100298939 (HRAS)
   05216 Thyroid cancer
    100298939 (HRAS)
   05221 Acute myeloid leukemia
    100298939 (HRAS)
   05220 Chronic myeloid leukemia
    100298939 (HRAS)
   05218 Melanoma
    100298939 (HRAS)
   05211 Renal cell carcinoma
    100298939 (HRAS)
   05219 Bladder cancer
    100298939 (HRAS)
   05215 Prostate cancer
    100298939 (HRAS)
   05213 Endometrial cancer
    100298939 (HRAS)
   05224 Breast cancer
    100298939 (HRAS)
   05223 Non-small cell lung cancer
    100298939 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100298939 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    100298939 (HRAS)
   05161 Hepatitis B
    100298939 (HRAS)
   05160 Hepatitis C
    100298939 (HRAS)
   05163 Human cytomegalovirus infection
    100298939 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100298939 (HRAS)
   05165 Human papillomavirus infection
    100298939 (HRAS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100298939 (HRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100298939 (HRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    100298939 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    100298939 (HRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100298939 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100298939 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100298939 (HRAS)
   01522 Endocrine resistance
    100298939 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    100298939 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    100298939 (HRAS)
   04031 GTP-binding proteins [BR:bta04031]
    100298939 (HRAS)
Membrane trafficking [BR:bta04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    100298939 (HRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    100298939 (HRAS)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100298939 (HRAS)
  Exosomal proteins of colorectal cancer cells
   100298939 (HRAS)
GTP-binding proteins [BR:bta04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    100298939 (HRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N CdhD CbiA
Other DBs
NCBI-GeneID: 100298939
NCBI-ProteinID: NP_001229275
Ensembl: ENSBTAG00000046644
VGNC: 29951
LinkDB
Position
29:50762262..50765201
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINHVKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKVRKLSPPDEGGPG
CLSCRCLLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacggagtataagctcgtggtggtgggcgccggtggcgtggggaagagcgccctgact
atccagctcattcagaatcacttcgtggacgagtacgaccccaccatcgaggactcctac
cggaagcaagtggtcatcgatggggagacgtgcctgctggacatcctggacacagcgggc
caggaggaatacagcgccatgcgagaccagtacatgcgcaccggggagggctttctctgc
gtgtttgctatcaaccacgtcaagtccttcgaggacatccaccagtaccgggagcagatc
aagcgggtgaaggactcggatgacgtgcccatggtgttggttgggaacaagtgcgacctg
gccgcgcgcaccgtggagtctcggcaggcccaggacctcgcccgcagctacggcatcccg
tacatcgagacctccgccaagacccgccagggcgtggaggatgctttctacaccctggtg
cgcgagatccggcagcacaaggtgcgcaagctgagcccgccggacgagggcggccccggc
tgcctgagctgcaggtgcctgctctcctga

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