| Entry |
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| Name |
(RefSeq) ATP-binding cassette sub-family C member 4
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
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| Pathway |
| bta04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:bta00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
100337053
09132 Signal transduction
04024 cAMP signaling pathway
100337053
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
100337053
04981 Folate transport and metabolism
100337053
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100337053
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:bta02000]
100337053
Transporters [BR:bta02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
100337053
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
12:70791883..71843698
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| AA seq |
1333 aa
MLQVFPERKPNPLQDANLCSRLVFWWINPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEEL
QGYWDQEVKRAEKDAREPSLMKAIIKCYWKSYLPFAIFKLFEEIFRVLLPTYFEDLLTYF
KNYDPSDSGALFKAYGYTAVLNVCFLILNILHNFFFYYTQRIGMRLRVAMCHIIYRKTLR
LSNLAIGKTTTGQIVNLVSNDVNRFDWVTICLHSLWIGPLMAITVIILLWMEIGISSLAG
MALLIILMLLQSFSGKLFLSLRSKIAAFTDTRLRTMNEVITGIRTIKMYAWEKSFAELIT
RLRRKEISKILRSSYLYGMHFIFFDTAIRVILFVTFTTYVLLGNTITVNQVFLAITLYQV
VQFTGLLLFPMAIENVAETVASVQRIKNFLLLGELPQCDHQLPSDGKTVVNVQDFTAFWD
KELRTPALQGVSFTVRPGELLAVVGPVGAGKSSLLSAVLGELPPSQGQVSVHGRIVYVSQ
KPWLFSGTVRNNILFGKKYEEEWYEKVIKACALEEDLRLLGDEEIIKIGDGRTQLSEGQK
ARICLARAMYQDADIYLLDDLLSAVDAGVSRHLFEQCVHQALKEKITILVTHQLQYLKDA
SQILMLKDGIVIERGTYSEFLKSGIDIFSRFEKGNEQSAPSPVPGTPTVISESLVQSLQS
PRRSLKDAAPEDQETENIQVVLPLECHLKGKVGFKTFKNYFTAGAHWPVIIFLILVNIAA
QVAYILQDWWLAFWANVQSDLYFGGYLKEDEDVVFVLNWYLRVYSGLTVSTVLFGITRSL
LIFCILVNSSQTLHKIMLETILRTQVLFFHINPIGRILNRFTKDIGHMDELLPLIFLDFI
QTFLLVVGVVGVMVAAIPWIAIPMVPFGIIFFVLQWYFFRTSRNVKRLECTTRSPVFSHL
ASSLRGLWTIRAYKAEQKFQELFDSHQDLHSEAWFLLLTTSRWLAVYLDVICAIFVTVVA
FGALILVETLDLGQVGLALSLTITLTGMFQWCVKQSAEVENMMISVERVIEYTDLKKEEP
WEHTPSFLLLEGKIVFDNVKFRHSLCEPLILKDLRACIDSGQKLGIVGRTGAGKSSLIAA
LFRLSEPKGGIWIDDILITRIGLNHSRKSMSVAPQEPVLFTGTVRKNLDPFNEYLGEELW
NVLEEVQLKETIQGLPGKMDTELAESGLNLSVGQRQLVCLARAILRKNKILILDKATSNV
DPRTDELIQKKIHEKFSECTVLTITHRLSTVIDCEWISVLDLGRWKECSQPYDLLQNKYS
LFYNMVQHLGKAEASALIERAKQVSLLPDFVISLSPASFFKISTWDLCALSNHKPPETKL
HDWVLTRRGGQVC |
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| NT seq |
4002 nt +upstreamnt +downstreamnt
atgttgcaggtgttcccggagaggaagcccaacccgctgcaggacgcgaacctctgctca
cgcctggtattctggtggataaatcccttgtttaaaattggtcacaaacggagattagaa
gaagatgacatgtactcggtgcttccagaagatcgctcccagcaccttggagaagaactg
caagggtactgggatcaagaagttaagagagctgagaaagatgcacgggagccttcttta
atgaaagcaatcataaagtgttactggaaatcctatttgccttttgcaatttttaagctt
tttgaggaaatcttcagagtactattaccaacatattttgaggatttacttacttacttt
aaaaactatgatccctctgattctggggctttgttcaaagcctatggctacactgctgta
ctgaatgtctgctttttaattttgaacattctgcacaactttttcttctattacactcag
cgtataggaatgagattaagagtagccatgtgccatattatttaccgcaagacacttcgc
ctgagtaacttggccatagggaagaccaccacaggccagatagtcaacctggtgtccaac
gatgtgaataggtttgactgggtaacaatatgcttgcacagcctgtggattgggccactt
atggctatcacagtaatcatcctgctctggatggaaataggaatatcatctcttgctggg
atggcactccttattattttgatgcttttgcaaagcttctctgggaagttgtttttatca
ctccggagtaagattgcagctttcacagacaccaggctcaggaccatgaatgaagttata
actggcatcagaacaataaaaatgtatgcttgggaaaagtcatttgcagagcttattacc
agattgagaaggaaggaaatttccaagattctgagaagttcctacctttatggaatgcat
tttatattctttgacactgcaatcagagtcatcctttttgtcacctttaccacctatgtg
cttcttggcaacacgatcacagttaaccaagtgtttttggccataacactgtaccaagtt
gtgcagtttacaggccttctcctcttccccatggccatcgagaatgtagcagaaacagtc
gctagtgtccaaagaatcaagaactttctgttacttggtgagctaccacagtgtgatcat
cagctgccatcagatggtaaaacagttgtgaacgtgcaagatttcactgctttttgggat
aaggaattaagaaccccagctctacaaggcgtttcctttactgtcagacctggtgaactg
ctagctgtggtcggacctgtgggcgcaggaaagtcctcactgttaagcgctgtgctggga
gagctgcccccgagccagggacaggtcagtgtgcacgggaggattgtgtatgtgtctcag
aagccctggctgttctcaggaactgtgaggaataacattttatttgggaagaaatatgaa
gaagaatggtatgaaaaagtaataaaggcttgtgctttggaagaggatttacggcttctg
ggggatgaagaaataattaagataggagatggaagaacacagctgagtgaagggcagaaa
gctcggatatgccttgcaagagccatgtatcaggatgcagacatctacctcctggacgat
ctgctcagcgcagtggatgcaggagtcagcaggcacttgttcgaacagtgtgttcatcag
gccttgaaggagaagatcacaattttagtcactcatcagttgcaatacctaaaagatgca
agtcagattctgatgttgaaagatgggatagtgatagaaagaggaacttactctgagttc
ctgaaatccgggatagatattttttcccgttttgagaaggggaatgagcaatctgcacca
tctccagttccaggaactcccactgtgatctctgagtctttggttcagtctctccagtct
cccagacgctcattgaaagatgcggctccagaagaccaagaaactgagaatatacaggtt
gtactacctctagagtgccatttgaaaggaaaagttggttttaagacctttaagaattac
ttcacagctggtgctcactggcctgtcatcatcttccttattctagtaaacatagcagct
caggttgcctacatcctgcaggattggtggcttgcattctgggcgaatgtacaaagtgac
ctgtattttgggggatatttgaaagaagatgaagatgtagtatttgtgctgaactggtac
ttaagagtttattcagggttaactgtgtctactgtcctttttggtatcacaaggtctctg
ttgatattctgcatccttgttaattcttcacaaactttgcacaagataatgttggagacc
attttaagaactcaggtattgttcttccatataaatccaataggaagaattttgaatcgt
ttcaccaaagacattgggcatatggatgagttactgcccctgatatttcttgatttcatc
cagacatttctgcttgtggttggtgtggtgggagtgatggtggctgcgattccttggatt
gctatacctatggttccctttggcatcattttctttgtgctccagtggtatttctttagg
acatcacgaaatgtgaaacgcctggaatgtacaactcggagcccggtgttttcccactta
gcatcttctctccggggactctggaccatccgagcatacaaagctgaacagaaatttcag
gagctatttgactcacaccaggatttgcactcagaggcttggttcctgcttttgacgacg
tcccgatggctcgctgtgtatctggatgtcatctgtgccatctttgtcactgttgttgcc
tttggggccctgattctggtagaaactttggatctcgggcaggttggcctggcgctgtca
ctcaccatcacactcacagggatgttccagtggtgcgtcaagcaaagtgccgaagtggag
aatatgatgatttcagtagaaagggttattgaatatacagaccttaagaaagaagagccc
tgggaacatacgccatccttcctgctccttgaaggaaagattgtctttgataatgttaag
ttcaggcacagcttatgtgagcctctgatattgaaggacctgagagcatgcattgactca
ggacaaaagcttggcattgtgggaagaacaggagctggaaaaagttcccttattgctgca
ctttttagattgtcagaacctaaaggtggcatttggattgatgacatcttgataacccgt
attggacttaaccattcacggaagagtatgtcagttgcacctcaggaacctgttttattc
actggaacagtgaggaaaaatctggatccctttaatgagtatttgggagaagaactgtgg
aatgtcttggaagaggtacaacttaaagaaaccatccaaggtcttcctggtaaaatggat
actgaattagcagaatcaggattgaacttgagtgttggacagagacaactagtatgcctt
gccagggctattctcaggaaaaataagatattgattcttgacaaagccacatccaatgtg
gatccaagaacagatgagttaatacaaaaaaaaatccatgagaaattttctgagtgcact
gtgctaaccatcacacacaggttgagcaccgttattgactgtgaatggatatcggttttg
gatttagggagatggaaagaatgtagccagccatatgatttgctgcaaaataaatatagc
ctgttttacaacatggtgcaacacctgggtaaggcagaggcctctgccctcattgaaagg
gcaaaacaggtgagtctgctgcctgactttgtaattagtttgtctccagcttcattcttc
aaaatctccacctgggatctctgtgccctttccaatcataaacctccagagactaagctt
catgactgggtcttaacaagacgtggtgggcaagtctgctga |
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