Bos taurus (cow): 112442685
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Entry
112442685 CDS
T01008
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X2
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
bta
Bos taurus (cow)
Pathway
bta04140
Autophagy - animal
bta04141
Protein processing in endoplasmic reticulum
bta04210
Apoptosis
bta04932
Non-alcoholic fatty liver disease
bta05010
Alzheimer disease
bta05012
Parkinson disease
bta05014
Amyotrophic lateral sclerosis
bta05016
Huntington disease
bta05017
Spinocerebellar ataxia
bta05022
Pathways of neurodegeneration - multiple diseases
bta05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112442685 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112442685 (ERN1)
09143 Cell growth and death
04210 Apoptosis
112442685 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112442685 (ERN1)
05012 Parkinson disease
112442685 (ERN1)
05014 Amyotrophic lateral sclerosis
112442685 (ERN1)
05016 Huntington disease
112442685 (ERN1)
05017 Spinocerebellar ataxia
112442685 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
112442685 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112442685 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112442685 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
112442685 (ERN1)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
112442685 (ERN1)
Protein kinases [BR:
bta01001
]
Serine/threonine kinases: Other
IRE family
112442685 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Pkinase_fungal
Kdo
APH
PQQ_2
PQQ
Motif
Other DBs
NCBI-GeneID:
112442685
NCBI-ProteinID:
XP_024836722
Ensembl:
ENSBTAG00000016799
VGNC:
58373
LinkDB
All DBs
Position
19:complement(48268459..48350794)
Genome browser
AA seq
857 aa
AA seq
DB search
MGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNA
TYFDYAAALPEDGGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGL
RKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASP
SMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRN
YWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVIDLVDQTSENAPTT
VSPDVEEKFDHAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSIHQQRQLQHQ
QFQKELEKIQLLQQQQLPFHPPGDAAQDAELQDSSGQYSESSATSSPSTSPRASNHSLHS
TGCTSKAVTSPFLEQDDEDEETGMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVK
RILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFA
HLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLA
VGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSL
QRQANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQL
QFFQDVSDRIEKEALDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGSSVRD
LLRAMRNKKHHYRELPEEVQQTLGALPDDFVRYFTSRFPHLLSHTYRAMELCCHERPFQP
YYHEPPEPQPPVTADAL
NT seq
2574 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaaaagcaggacatttggtacgttatcgacctcctgactggggagaagcagcag
accctgtcatcagcctttgcagacagcctctgcccatcaacctctcttctgtatctgggg
cgaacagagtacaccatcaccatgtacgacaccaagacccgcgagctgcgctggaacgcc
acctacttcgactacgcggccgcgctgcccgaggacggtggggactacaagatgtcccat
tttgtgtccaatggcgatgggctggtggtgacggtggacagcgagtctggggacgtcctg
tggatccaaaactatgcttcccccgtggtggccttttacatctggcagcgcgagggcctg
cggaaggtgatgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtcg
ggggaggtggggcgcatcaccaagtggaagtacccattccccaaggagacggaggccaag
agcaagctgacgcccaccctgtatgtggggaaatactccaccagcctctatgcttccccc
tcgatggtgcatgagggtgtcgccgttgtgccccggggcagcacccttcctttgctggaa
ggcccccagaccgacggtgtcaccatcggggacaaaggggagtgtgtgatcacgcccagc
acggacctgaagttcgacccaggactcaaaggcaagagcaagctcaactacctgcggaac
tactggctgctcatcggacaccacgaaaccccactgtccgcgtccaccaagatgctggag
cgcttccccaacaacctgcccaaacaccgggagaatgtgattcccgccgactcggagaag
aagagctttgaggaggtcattgacctggttgaccagacttcagaaaatgcacctaccacg
gtttctccggacgtggaagagaagttcgatcatgcccctgccaagcccgaggcccctgtg
gactccatgctcaaggacatggccaccatcatcctgagcaccttcctgctcatcggctgg
gtggctttcatcatcacttaccccctgagcatccaccagcagcgacagctccagcaccag
cagttccagaaggaactggagaagatccagctcctgcagcagcagcagctgcccttccac
ccgcccggggacgcggcacaggacgccgagctccaggactcatccggccagtactcggag
agctcggccaccagcagccccagcacgtccccccgagcctccaaccactcgctccactcc
accggctgcacctccaaggctgtcaccagccccttcctggagcaggacgatgaggatgag
gagaccggcatggtgatagttgggaaaatctccttctgtccaaaggatgtcctgggccat
ggagctgagggcacgatcgtgtaccggggcatgtttgacaatcgtgacgtggcagtcaag
aggatcctgcccgagtgtttcagtttcgcggaccgtgaggtccagctgctgagagagtcg
gacgagcacccaaacgtgatccgctacttctgcactgagagggaccggcagttccagtac
atcgccatcgagctgtgcgcggccacgctgcaggagtacgtggagcagaaggatttcgcc
cacctcggcctggagcccatcaccctgctgcaacagaccacctcgggcctggcccacctg
cactccctcaacattgttcacagagacctgaagccccacaacatcctcctctccatgccc
aacgcacacggcaggatcaaggccatgatctccgacttcggcctctgcaagaagctggcc
gtgggcaggcacagcttcagccgccgctcgggggtgccgggcaccgaaggttggatcgcc
ccggagatgctgagcgaagactgcaaggagaaccccacctacacggtggacatcttctcc
gcgggctgcgtcttctactacgtgatatctgagggcagccacccctttggcaagtccctg
caacgccaggccaacatcctcctgggtgcctacagccttgactgcctgcacccagagaag
catgaggacgtcattgcccgggaattaatagagaagatgatcgccatggacccccagaag
cgcccgtcagcgaagcatgtgctgaaacaccctttcttctggagcctggaaaagcagctc
cagttcttccaggacgtgagtgaccggatagagaaagaggccctggatggcccgatagtg
aagcagctggagcgcggcgggcgggccgtggtgaagatggactggcgggagaacatcacc
gtccccctgcagacagatctgcggaaattcagaacctataaaggcagttcggtccgagat
ctcctcagagccatgaggaataagaagcaccactaccgggagctgcccgaggaggtgcag
cagacgctgggcgccctccctgacgacttcgtgcgctacttcacctcccgcttcccccac
cttctctcacacacctaccgtgccatggagctgtgctgccacgagaggcccttccagccc
tactaccacgagccccccgagccccagccccccgtgactgcagacgccctctga
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