Bos taurus (cow): 281165 Help Entry 281165            CDS       T01008                                  Symbol FLNA Name (RefSeq) filamin-A   KO K04437   filamin-A Organism bta  Bos taurus (cow) Pathway bta04010   MAPK signaling pathway bta04510   Focal adhesion bta04518   Integrin signaling bta05132   Salmonella infection bta05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     281165 (FLNA)   09133 Signaling molecules and interaction    04518 Integrin signaling     281165 (FLNA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     281165 (FLNA)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     281165 (FLNA)   09171 Infectious disease: bacterial    05132 Salmonella infection     281165 (FLNA)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:bta04812]     281165 (FLNA)    04147 Exosome [BR:bta04147]     281165 (FLNA) Cytoskeleton proteins [BR:bta04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Cross-linking proteins      281165 (FLNA)   Intermediate filaments    Intermediate filament-binding proteins     281165 (FLNA) Exosome [BR:bta04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    281165 (FLNA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Filamin Ig_GEX2_N CH Y_Y_Y CFSR Motif Other DBs NCBI-GeneID:  281165 NCBI-ProteinID:  NP_001193443 BGD-bta:  BT10873 Ensembl:  ENSBTAG00000011190 VGNC:  29033 UniProt:  F1N169 LinkDB All DBs Position X:complement(37397606..37422676) Genome browser AA seq 2647 aa AA seqDB search MSSSHSRAGQSAAGAVLGIGADTRDAEMPATEKDLAEDAPWKKIQQNTFTRWCNEHLKCV SKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIK LVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQTPKQRLLGWIQNKL PQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQ VITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKK RAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLF AGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVI QDPAGQKGTVEPQLEARGDSTYRCSYQPSVEGVHMVHVTFAGVPIPRSPYTVTVGQACNP GACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGF EYYPMIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVE AIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFM ADIRDAPQDFHPDRVKARGPGLEKTGVAVNKSAEFTVDAKHGGKAPLKVQVQDNEGCPVE ATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVA KTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTVKYTP RGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELSKPTHFTVNTK AAGKGKLDVQFSGPAKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGINVTYGGDAIPKSP FSVGVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVLSKIVGPSGAAVPCKV EPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFSLEAVPPTKPSKVKAFGPGLQGG SAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILF ADTHIPGSPFKAHVVPCFDPSKVKCSGPGLERATAGEAGQFHVDCSSAGSAELTIEIRSE AGLPAEVHIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGIQC YGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDCGDGTYKVE YTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVET RGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYVPYEAGTYSLNVTYGGHQVPGSPFKV PVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGMAPLQVKVQGPKGLVEPVDVV DNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGV PASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILI KYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAG KGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTA LAGDQPTAQPSLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVSSLRPFDLVIPFTIK KGEVTGEVRMPSGKVAQPAITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYV DYVNCGHVTAYGPGLTHGVVNKPAIFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTC SVSYLPVLPGDYSILVKYNEQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDL SLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVIS QSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDG TCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHC DLSLKIPEISIQDMTAQVTSPSGKSHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQH VPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSK AEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSL QESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIY LIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGITGSPAEFIVNTSNAGAG ALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIAGSPFKARVTGHR LVSNHSLHETSSVFVDSLTKTATIPQHSAPGPGPTDASKVLAKGVGLSKAYMGQKSSFTV DCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGS PYRVLVP NT seq 7944 nt NT seq  +upstreamnt  +downstreamnt atgagtagctcccactctcgggcgggccagagcgctgcgggcgcggttctgggcatcggt gccgacacacgagacgccgagatgccggccaccgagaaggacctggcggaggatgcgccg tggaagaagatccagcagaacacgttcacgcgctggtgcaacgagcacctcaagtgcgtg agcaagcgcatcgccaacctgcagacggacctgagcgacgggctgcggcttatcgcgctg ctcgaggtgctcagccagaagaagatgcaccgcaagcacaaccagaggcccaccttccgc cagatgcagcttgagaacgtgtcggtggcgctcgagttcctggaccgcgagagcatcaag ctcgtgtccatcgacagtaaggccatcgtggacgggaacctcaagttgatcctgggcctc atctggaccctgatcctgcactactccatctccatgcccatgtgggatgaggaggaggac gaggaggccaagaagcagacccccaagcagaggctgctgggctggatccagaacaagctg ccacagctgcccatcaccaacttcagccgtgactggcagagcggcagagccctgggcgcc ctggtcgacagctgtgccccgggcctgtgccccgactgggattcctgggatgccagcaag cccgtgaacaatgcacgggaagccatgcaacaagctgatgactggctgggcatccctcag gtgatcacccccgaggagattgtggaccccaacgtggatgagcactccgtcatgacctac ctgtcccagttccccaaggccaagctgaaaccaggggctcccctgcggcccaaactcaac ccgaagaaagcccgagcctatgggccaggcattgagcctacaggcaacatggtaaagaag agggcagagttcacggtggagaccagaagcgccgggcagggagaggtgctggtatacgtg gaggacccggctgggcaccaggaggaggccaaggtgaccgccaataacgacaagaaccgt accttctctgtctggtatgtccccgaggtgacggggactcacaaggtcaccgtgctcttt gccggccagcacattgccaagagccccttcgaggtgtacgtggacaagtcccagggagac gccagcaaagtgactgcccagggccctggcctggagcccagcggcaacattgccaacaag accacctactttgagatcttcacggcgggtgcgggcatgggtgaggtggaggtggtgatc caggacccagcaggccagaagggtaccgtggagcctcagctggaggcccggggcgacagc acgtatcgctgcagctaccagcccagtgtggagggcgtccacatggtgcacgtcactttc gccggggtgcccatccctcgcagcccctacacagtcactgtgggtcaagcttgtaaccca ggtgcctgccgcgctgtcggccggggtctccagcccaagggtgtgcgagtgaaggagacg gccgacttcaaagtgtacacaaagggggcgggcagcggagagctgaaggtcaccgtaaag ggccccaagggtgaagagcgtgtgaagcagaaggacctgggcgatggtgtctatggtttc gagtattaccccatgatccccggcacatacactgtcacgatcacgtggggtggccaaaat attgggcgcagtcccttcgaggtgaaagtgggcactgagtgcggcaatcagaaggtgcgg gcatggggccctgggctggagggcggtgttgtcggcaagtctgcagactttgtcgtggag gccattggcgacgacgtgggcaccctgggcttctcggtggagggcccatcgcaggctaag atcgagtgtgacgacaagggcgatggctcctgcgatgtgcgctactggccacaggaggct ggtgagtacgcggtgcacgtgctgtgcaacagtgaggacatccgtctcagccccttcatg gccgacatccgcgacgcgccccaggatttccatccagacagggtgaaggcacgtgggcct ggattggagaagaccggcgtggctgtgaacaagtcagcagagttcacagtggatgccaag cacggcgggaaggctcctctcaaggtccaagtccaggacaatgagggctgcccagtggag gcaacggtcaaggacaatggcaatggcacttacagctgctcctatgtgccccggaagcca gtgaagcacacggccatggtgtcctggggaggtgtcagcatccccaacagccccttccgg gtgaatgtgggtgccggcagccacccgaacaaggtcaaggtgtacggcccaggagtggca aagacaggactcaaggctcacgagcccacctacttcactgtggactgcacggaggctggc cagggtgatgtcagcatcggcatcaagtgtgccccgggtgtggtgggccctgccgaggcc gacatcgacttcgacatcatccgcaacgacaacgacaccttcacggtcaagtacaccccc cgcggggctggcagctacaccatcatggtgctctttgctgaccaggctacgcccaccagc cccatccgggtcaaagtggagccttcccatgatgccagcaaggttaaggcagaaggtccc ggcctcagtcgcaccggggtcgagcttagcaaacccacccacttcacggtcaacaccaaa gctgccggcaaaggcaagctggatgtccagttctcggggccggccaaaggggatgcagtg cgtgacgtggacatcattgaccatcatgacaacacctataccgtcaagtacacgcctgtg cagcagggcccagtgggcatcaatgtcacttacggaggtgatgctattcccaaaagcccc ttctcagtgggggtgtctccaagcctggacctcagcaagattaaggtgtccggcctggga gaaaaggtggatgttggcaaagaccaggagttcacggtcaagtccaagggcgccggtggc cagggcaaagtgctgtcgaagatcgtgggcccttcaggggcagcggttccctgcaaggtg gagccaggcctcggggctgacaacagcgtggtgcgctttgtgccccgtgaagaggggccc tatgaggttgaggtgacctatgatggcgtacctgtgcctggcagccccttttccctggaa gccgtgccgcccaccaagcctagcaaggtgaaagccttcgggccagggctgcaggggggc agtgcagggtctcctgcccgcttcacgatcgacacaaagggtgccggcacaggcggcctg ggcctgacggtcgaaggcccttgtgaagctcagctcgaatgcctggacaacggggatggc acgtgctctgtgtcctatgtgcccactgagcctggggactacaacatcaacatcctcttc gctgacacccacatccccggctccccattcaaggcccacgtggttccctgcttcgacccg tccaaggtcaagtgctcaggccccgggctggagcgggccacggctggggaggccggccag ttccatgtggactgctcgagtgcgggcagtgcggagctgaccatcgagatccgctccgag gcagggctgccggccgaggtgcacatccaggaccacggtgacggcacgcacaccatcacc tacatccccctgtgccctggagcctacaccgtcaccatcaagtacggcggccagcctgtg cccaacttcccaagcaagctgcaggtggagcccgcagtggatacctcgggcatccagtgc tatgggcccgggattgagggtcaaggtgtcttccgagaagccaccaccgagttcagcgtg gatgcccgggctctgacgcagactggagggccccacgtcaaggctcgcgtggccaacccc tcgggcaacctgactgagacctatgtgcaggactgtggtgatggcacatacaaagtggag tacacaccatatgaggagggactccactctgtggacgtgacctacgacggcagtcctgtg cccagcagccccttccaggtgccagtgactgaaggctgcgacccctcccgagtgcgtgtc catgggccaggcatccaaagcggcaccaccaacaagcccaacaagttcactgtggagacc aggggagctggcacagggggcctgggcttggctgttgagggcccctctgaggccaagatg tcctgcatggacaacaaggatggcagctgctcggttgagtatgtcccctacgaggccggc acctacagccttaacgtcacttacggcggccaccaagtgccaggcagtcctttcaaggtc cctgtgcacgatgtgacagacgcgtccaaggtcaaatgctctgggcctggcctgagcccg ggcatggtccgtgccaacctacctcagtccttccaggtggacacgagcaaggctggcatg gccccactgcaggtcaaagtgcaggggcccaaaggcctggtggagccggtggacgtggtg gacaatgccgatggcacccagactgtgaactatgtgcccagccgtgaggggccctacagc atctcagtgctgtatggagacgaagaggtaccccgcagccccttcaaggttaaggtgctg cctacacatgatgccagcaaggtcaaggccagtggcccagggctcaacaccacgggtgtg cctgccagcctgcctgtggagttcactattgatgccaaggacgctggggagggcctgctg gctgtccagatcacggacccggagggcaagcccaagaagacacacatccaagacaaccac gacggcacgtacacagtggcctacgtgccagacgtgacaggccgctacactatcctcata aagtatggtggtgacgagatccccttctccccataccgtgtccgcgccgtgcccacgggg gatgccagcaagtgcaccgtcacagtgtcaatcggaggtcacgggctaggtgctggcatc ggccctaccatccagatcggggaggagactgtgatcactgtggacaccaaggcagcgggc aaaggcaaggtcacctgtactgtgtgcacccccgatggctctgaggtggacgtggacgtg gtcgagaatgaggatggcacctttgacatcttctacacggctccccagcccggcaaatac gtcatctgcgtgcgcttcggtggtgaacacgtgcccaacagtcccttccaagtgacggct ctggctggagaccagcccacggcacagccctcattacggcctcagcagctggcaccacca tatacctacgcccaggggggccagcagacctgggccccagaaaggcccctggtgggggtc aacgggctagatgtgagcagcctgaggccctttgaccttgtcatccccttcaccatcaag aagggcgaggtcactggggaggtgcggatgccctcgggcaaggtggcacagcccgccatc accgacaacaaggatggcactgtgactgtgcgctacgcccccagtgaagccggcctgcac gagatggatatccgctatgacaacatgcacatcccaggcagccccctacagttctacgtg gattatgtcaactgtggccatgtcacagcctatgggccaggcctcacccatggggtggtg aataagcccgctatcttcaccgtcaacaccaaggatgcgggcgaggggggcttgtccctg gccattgagggcccctccaaagcagagatcagctgcaccgacaaccaggatgggacgtgc agtgtctcctacctgcccgtgttacctggtgactacagcatcctggtcaagtacaacgaa cagcatatcccgggcagccccttcactgccagggtcacaggtgacgactccatgcgcatg tcccacctgaaggtgggctctgccgccgacatccccatcaacatctcggagacggacctc agcctgctgaccgccacagtggtgcccccctcgggccgggaagaaccctgtctgctgaag cggctgcgcaacggccacgtggggatctcattcgtgcccaaggagacaggggaacacctg gtgcacgtgaagaagaatgggcagcatgtggcaagcagccccattccggtggtgatcagc caatcggagatcggggatgccagccgtgtgcgggtctcgggccagggcctccacgaaggc cacacctttgagccagcagagtttatcattgatacacgtgatgcaggctatggggggctc agcctgtccatcgagggtcccagcaaagtagacatcaacacagaggacctggaggatggc acatgcagggtcacctactgccccacggagcctggcaactatatcatcaacatcaagttt gctgaccagcacgtgcctggcagccccttctccgtgaaggtgacaggcgaggggcgtgtg aaagagagcatcacgcgcaggcgacgggccccatcggtggctaatgttggcagtcactgt gacctcagcctcaagatcccagaaattagcatccaggacatgacagcccaggtgactagc ccatcaggcaagagccacgaggccgagattgtggaaggggagaaccatacctattgcatc cgctttgtgccagctgagatgggcatgcacacggtcagcgtcaagtacaagggccagcac gtgcccgggagccctttccagttcaccgtggggcccctgggggaagggggagcccacaag gtccgtgccgggggccctggcctggaaagggctgaagctggagtgccagccgagttcagc atttggacccgggaagctggcgcggggggcctggccattgctgtcgagggccccagcaag gccgagatctccttcgaggaccgcaaggatggctcctgtggcgtggcttacgtggtccag gagccaggtgactatgaggtgtcagtcaagttcaacgaggagcacatccccgatagccct ttcgtggtgcctgtggcttctccgtctggtgacgcccgccgccttactgtttctagtctt caggagtcagggctaaaggtcaaccagccagcctcttttgcagtcagcctgaatggggcc aagggggcaatcgatgccaaggtgcacagcccctcaggagccctggaggagtgctatgtc accgagatcgaccaagataagtacgctgtgcgctttatcccacgggagaatggcatctac ctgattgatgtcaagttcaacggcacccacatcccggggagccccttcaagatccgagtt ggggagcctgggcatggaggggacccaggcctggtgtctgcttatggagctggcttggaa ggcggcatcacagggagcccagctgagtttatcgtgaacaccagcaatgcgggcgctggt gccctctcagtcaccatcgacgggccttccaaggtgaagatggattgccaagagtgcccc gagggctaccgcgtcacctacactcccatggcacctggcagctacctcatctccatcaag tacggcggcccctaccacattgcgggcagccccttcaaggccagagtcacaggtcaccgc ctcgtcagcaaccacagcctccatgagacatcatctgtgtttgtggactccctgaccaag actgccaccatcccccagcacagtgccccaggcccgggtcccactgatgccagcaaggtg ctggccaaaggcgtggggctgagcaaggcctacatgggccagaagagcagcttcacggtg gactgcagcaaagcaggcaacaacatgctgctggtgggcgtgcatgggccccggacgccc tgtgaagagatcctggtgaaacacgtgggcagcaggctctacagtgtgtcctacctgctc aaggacaagggggagtacacgctggtggtcaagtggggtgacgagcacatcccgggcagc ccctaccgagtcctggtgccctga

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