KEGG   Bos taurus (cow): 281239
Entry
281239            CDS       T01008                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I preproprotein
  KO
K05459  insulin-like growth factor 1
Organism
bta  Bos taurus (cow)
Pathway
bta01521  EGFR tyrosine kinase inhibitor resistance
bta01522  Endocrine resistance
bta04010  MAPK signaling pathway
bta04014  Ras signaling pathway
bta04015  Rap1 signaling pathway
bta04066  HIF-1 signaling pathway
bta04068  FoxO signaling pathway
bta04081  Hormone signaling
bta04114  Oocyte meiosis
bta04115  p53 signaling pathway
bta04150  mTOR signaling pathway
bta04151  PI3K-Akt signaling pathway
bta04152  AMPK signaling pathway
bta04211  Longevity regulating pathway
bta04213  Longevity regulating pathway - multiple species
bta04510  Focal adhesion
bta04550  Signaling pathways regulating pluripotency of stem cells
bta04730  Long-term depression
bta04750  Inflammatory mediator regulation of TRP channels
bta04913  Ovarian steroidogenesis
bta04914  Progesterone-mediated oocyte maturation
bta04935  Growth hormone synthesis, secretion and action
bta04960  Aldosterone-regulated sodium reabsorption
bta05200  Pathways in cancer
bta05202  Transcriptional misregulation in cancer
bta05205  Proteoglycans in cancer
bta05214  Glioma
bta05215  Prostate cancer
bta05218  Melanoma
bta05224  Breast cancer
bta05410  Hypertrophic cardiomyopathy
bta05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    281239 (IGF1)
   04014 Ras signaling pathway
    281239 (IGF1)
   04015 Rap1 signaling pathway
    281239 (IGF1)
   04066 HIF-1 signaling pathway
    281239 (IGF1)
   04068 FoxO signaling pathway
    281239 (IGF1)
   04151 PI3K-Akt signaling pathway
    281239 (IGF1)
   04152 AMPK signaling pathway
    281239 (IGF1)
   04150 mTOR signaling pathway
    281239 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    281239 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    281239 (IGF1)
   04115 p53 signaling pathway
    281239 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    281239 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    281239 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    281239 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    281239 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    281239 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    281239 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    281239 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    281239 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    281239 (IGF1)
   04213 Longevity regulating pathway - multiple species
    281239 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    281239 (IGF1)
   05202 Transcriptional misregulation in cancer
    281239 (IGF1)
   05205 Proteoglycans in cancer
    281239 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    281239 (IGF1)
   05218 Melanoma
    281239 (IGF1)
   05215 Prostate cancer
    281239 (IGF1)
   05224 Breast cancer
    281239 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    281239 (IGF1)
   05414 Dilated cardiomyopathy
    281239 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    281239 (IGF1)
   01522 Endocrine resistance
    281239 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:bta04052]
    281239 (IGF1)
Cytokines and neuropeptides [BR:bta04052]
 Cytokines
  Growth factors (RTK binding)
   281239 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 281239
NCBI-ProteinID: NP_001071296
BGD-bta: BT11525
Ensembl: ENSBTAG00000011082
VGNC: 30076
UniProt: P07455 F2X2F0
LinkDB
Position
5:complement(66186011..66264048)
AA seq 154 aa
MGKISSLPTQLFKCCFCDFLKQVKMPITSSSHLFYLALCLLAFTSSATAGPETLCGAELV
DALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSAR
SVRAQRHTDMPKAQKEVHLKNTSRGSAGNKNYRM
NT seq 465 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aagcaggtgaagatgcccatcacatcctcctcgcatctcttctatctggccctgtgcttg
ctcgccttcaccagctctgccacggcgggacccgagaccctctgcggggctgagttggtg
gatgctctccagttcgtgtgcggagacaggggcttttatttcaacaagcccacggggtat
ggctcgagcagtcggagggcgccccagacaggaatcgtggatgagtgctgcttccggagc
tgtgatctgaggaggctggagatgtactgcgcgcctctcaagcccgccaagtcggcccgc
tcagtccgtgcccagcgccacaccgacatgcccaaggctcagaaggaagtacatttgaag
aacacaagtagagggagtgcaggaaacaagaactacagaatgtag

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