KEGG   Bos taurus (cow): 281440
Entry
281440            CDS       T01008                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
bta  Bos taurus (cow)
Pathway
bta04010  MAPK signaling pathway
bta04014  Ras signaling pathway
bta04015  Rap1 signaling pathway
bta04024  cAMP signaling pathway
bta04062  Chemokine signaling pathway
bta04071  Sphingolipid signaling pathway
bta04145  Phagosome
bta04148  Efferocytosis
bta04151  PI3K-Akt signaling pathway
bta04310  Wnt signaling pathway
bta04360  Axon guidance
bta04370  VEGF signaling pathway
bta04380  Osteoclast differentiation
bta04510  Focal adhesion
bta04520  Adherens junction
bta04530  Tight junction
bta04613  Neutrophil extracellular trap formation
bta04620  Toll-like receptor signaling pathway
bta04650  Natural killer cell mediated cytotoxicity
bta04662  B cell receptor signaling pathway
bta04664  Fc epsilon RI signaling pathway
bta04666  Fc gamma R-mediated phagocytosis
bta04670  Leukocyte transendothelial migration
bta04722  Neurotrophin signaling pathway
bta04810  Regulation of actin cytoskeleton
bta04932  Non-alcoholic fatty liver disease
bta04933  AGE-RAGE signaling pathway in diabetic complications
bta04972  Pancreatic secretion
bta05014  Amyotrophic lateral sclerosis
bta05020  Prion disease
bta05022  Pathways of neurodegeneration - multiple diseases
bta05100  Bacterial invasion of epithelial cells
bta05132  Salmonella infection
bta05135  Yersinia infection
bta05163  Human cytomegalovirus infection
bta05167  Kaposi sarcoma-associated herpesvirus infection
bta05169  Epstein-Barr virus infection
bta05170  Human immunodeficiency virus 1 infection
bta05200  Pathways in cancer
bta05203  Viral carcinogenesis
bta05205  Proteoglycans in cancer
bta05208  Chemical carcinogenesis - reactive oxygen species
bta05210  Colorectal cancer
bta05211  Renal cell carcinoma
bta05212  Pancreatic cancer
bta05231  Choline metabolism in cancer
bta05415  Diabetic cardiomyopathy
bta05416  Viral myocarditis
bta05417  Lipid and atherosclerosis
bta05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    281440 (RAC1)
   04015 Rap1 signaling pathway
    281440 (RAC1)
   04310 Wnt signaling pathway
    281440 (RAC1)
   04071 Sphingolipid signaling pathway
    281440 (RAC1)
   04024 cAMP signaling pathway
    281440 (RAC1)
   04151 PI3K-Akt signaling pathway
    281440 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    281440 (RAC1)
   04148 Efferocytosis
    281440 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    281440 (RAC1)
   04620 Toll-like receptor signaling pathway
    281440 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    281440 (RAC1)
   04662 B cell receptor signaling pathway
    281440 (RAC1)
   04664 Fc epsilon RI signaling pathway
    281440 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    281440 (RAC1)
   04670 Leukocyte transendothelial migration
    281440 (RAC1)
   04062 Chemokine signaling pathway
    281440 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    281440 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    281440 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    281440 (RAC1)
   04380 Osteoclast differentiation
    281440 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    281440 (RAC1)
   05205 Proteoglycans in cancer
    281440 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    281440 (RAC1)
   05203 Viral carcinogenesis
    281440 (RAC1)
   05231 Choline metabolism in cancer
    281440 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    281440 (RAC1)
   05212 Pancreatic cancer
    281440 (RAC1)
   05211 Renal cell carcinoma
    281440 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    281440 (RAC1)
   05163 Human cytomegalovirus infection
    281440 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    281440 (RAC1)
   05169 Epstein-Barr virus infection
    281440 (RAC1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    281440 (RAC1)
   05100 Bacterial invasion of epithelial cells
    281440 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    281440 (RAC1)
   05020 Prion disease
    281440 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    281440 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    281440 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    281440 (RAC1)
   05415 Diabetic cardiomyopathy
    281440 (RAC1)
   05416 Viral myocarditis
    281440 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    281440 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    281440 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    281440 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    281440 (RAC1)
   04031 GTP-binding proteins [BR:bta04031]
    281440 (RAC1)
Membrane trafficking [BR:bta04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    281440 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    281440 (RAC1)
  Macropinocytosis
   Ras GTPases
    281440 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    281440 (RAC1)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   281440 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   281440 (RAC1)
  Exosomal proteins of colorectal cancer cells
   281440 (RAC1)
  Exosomal proteins of bladder cancer cells
   281440 (RAC1)
GTP-binding proteins [BR:bta04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    281440 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 281440
NCBI-ProteinID: NP_776588
Ensembl: ENSBTAG00000053390
VGNC: 106889
UniProt: P62998
LinkDB
Position
25:38278421..38297359
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtgggagacggagctgtgggtaagacttgcctcctg
atcagttacactaccaatgcgtttcctggagaatatatccccactgtctttgacaactac
tctgccaatgtcatggtggatggaaaacccgtgaatctgggcttgtgggacacagccgga
caagaagattatgaccgattacgccccctgtcctacccgcagacagatgtattcttaatt
tgcttttctctcgtgagtcctgcatcatttgaaaatgttcgtgcaaagtggtaccctgaa
gtgcgacaccattgtcccaacacacccatcatcctggtggggacgaaacttgacctgagg
gacgataaagacacgatcgagaagctgaaggagaagaagctgacgcccatcacctacccg
cagggcttggccatggccaaggagatcggtgccgtcaaatacctggagtgctcggcgctc
acgcagcggggcctcaagacagtgtttgatgaggcgatccgggctgttctctgcccaccc
cccgtcaagaagcggaagaggaagtgcctgctcttgtga

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