Bos taurus (cow): 281480
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Entry
281480 CDS
T01008
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
bta
Bos taurus (cow)
Pathway
bta00020
Citrate cycle (TCA cycle)
bta00190
Oxidative phosphorylation
bta01100
Metabolic pathways
bta01200
Carbon metabolism
bta04714
Thermogenesis
bta04932
Non-alcoholic fatty liver disease
bta05010
Alzheimer disease
bta05012
Parkinson disease
bta05014
Amyotrophic lateral sclerosis
bta05016
Huntington disease
bta05020
Prion disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05208
Chemical carcinogenesis - reactive oxygen species
bta05415
Diabetic cardiomyopathy
Module
bta_M00009
Citrate cycle (TCA cycle, Krebs cycle)
bta_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
bta_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
281480 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
281480 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
281480 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
281480 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
281480 (SDHA)
05012 Parkinson disease
281480 (SDHA)
05014 Amyotrophic lateral sclerosis
281480 (SDHA)
05016 Huntington disease
281480 (SDHA)
05020 Prion disease
281480 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
281480 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
281480 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
281480 (SDHA)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
281480 (SDHA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Pyr_redox_2
Thi4
DAO
FAD_binding_3
HI0933_like
GIDA
Motif
Other DBs
NCBI-GeneID:
281480
NCBI-ProteinID:
NP_776603
Ensembl:
ENSBTAG00000046019
VGNC:
34388
UniProt:
P31039
LinkDB
All DBs
Position
20:complement(71804563..71827918)
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AA seq
665 aa
AA seq
DB search
MSGVAAVSRLWRARRLALTCTKWSAAWQTGTRSFHFTVDGNKRSSAKVSDAISAQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMESGECRGVIALCI
EERVHPPHQGQEHCHRHRSYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPAQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVNGQDQGVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKI
SSLYGDLRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGGPRREDFKE
RVDEYDYSKPIQGQQKKPFEQHWRKHTLSYVDIKTGKVTLEYRPVIDRTLNETDCATVPP
AIGSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggggttgccgctgtgtcgcgcttgtggcgcgcccggcgcctggcgctgacctgc
acgaagtggtcggcagcatggcagacaggaacccgcagttttcacttcaccgttgatggc
aataagaggtcgtccgctaaagtttcagatgcgatttctgcgcagtatccagttgtggac
catgagtttgatgccgtggtggttggtgccgggggggcaggcctgcgggccgcgttcggc
ctctctgaagcaggtttcaacacggcctgcgtcacgaagctcttccccaccagatcccac
actgtcgcggcccagggagggatcaatgccgccctggggaacatggaggaggacaactgg
cggtggcacttctacgacaccgtgaaaggctccgactggctgggggaccaggacgccatc
cattacatgaccgagcaggcccccgcctctgtggtggagctggagaattacggcatgccc
tttagcagaactgaagatggcaagatctaccagcgtgcctttggcggacagagcctcaag
ttcgggaagggtgggcaggcccatcgctgctgctgcgtggccgaccgcacgggccactcg
ctgctgcacacgttgtatggaaggtctctgcgctatgacaccagctactttgtggagtac
tttgctctggacctcctgatggagagcggggagtgccgcggtgtgatcgctctgtgcata
gaagaacgggtccatccaccgcatcagggccaggaacactgtcatcgccaccggagctac
gggcgcacctacttcagctgcacgtccgcccacaccagcaccggggacggcactgccatg
gtgaccagggctggcctgccctgccaggacctggagttcgtgcagttccaccccacaggc
atatatggcgctggctgtctcatcacagagggctgtcgtggagaggggggcatcctcatc
aacagccagggtgagaggttcatggagcgctacgcccccgtcgctaaggacctggcgtcc
agggatgtcgtgtcccggtccatgaccctggaaatccgcgagggaagaggctgtgggccc
gagaaggaccatgtgtacctgcagctgcaccacctgcccccagcacagctggctatgcgc
ctgcctggcatctcagagacggccatgatcttcgcgggcgtggacgtcaccaaggagccc
atccccgtgcttcccaccgtgcactacaacatgggtggcatccccaccaactacaagggg
caggttctgaggcacgtgaatggccaggaccagggtgtgcctggcctgtacgcatgcggg
gaggctgcctgcgcctcggtgcatggtgccaaccgtctgggtgcaaactcgctcctggac
ctggttgtcttcggccgggcgtgcgccctgagcatcgcagagtcctgcagacccggagat
aaagttccctcgattaaaccaaatgctggggaagaatctgtcatgaatcttgacaaattg
agatttgccaatggaagcataaggacatcggaactgcgactcaacatgcagaagtcgatg
cagagccatgccgcggtgttccgtgtggggagtgtgctgcaggaaggctgtgagaagatc
agcagcctctacggagacctgcggcatctgaagacgttcgacaggggaatggtctggaac
actgacctggtggagaccctggagctgcagaacctgatgctttgtgctctgcagaccatc
tacggagcggaggcccggaaggagtcgcgcggcggcccacgcagggaggacttcaaggag
agggttgacgagtacgattactccaagcccatccaggggcagcagaagaagccctttgag
cagcactggaggaagcacacgctctcctacgttgacatcaagactgggaaggtcaccctg
gagtacagacctgtaatcgacagaactttgaacgagactgactgcgccactgttccccca
gccatcggctcctactga
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