Bos taurus (cow): 281590 Help Entry 281590            CDS       T01008                                  Symbol ACACA Name (RefSeq) acetyl-CoA carboxylase 1   KO K11262   acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism bta  Bos taurus (cow) Pathway bta00061   Fatty acid biosynthesis bta00620   Pyruvate metabolism bta00640   Propanoate metabolism bta01100   Metabolic pathways bta01212   Fatty acid metabolism bta04152   AMPK signaling pathway bta04910   Insulin signaling pathway bta04922   Glucagon signaling pathway bta04936   Alcoholic liver disease Module bta_M00082   Fatty acid biosynthesis, initiation Brite KEGG Orthology (KO) [BR:bta00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     281590 (ACACA)    00640 Propanoate metabolism     281590 (ACACA)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     281590 (ACACA)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     281590 (ACACA)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     281590 (ACACA)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     281590 (ACACA)    04922 Glucagon signaling pathway     281590 (ACACA)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     281590 (ACACA) Enzymes [BR:bta01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      281590 (ACACA)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      281590 (ACACA)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      281590 (ACACA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 Motif Other DBs NCBI-GeneID:  281590 NCBI-ProteinID:  NP_776649 BGD-bta:  BT12301 Ensembl:  ENSBTAG00000017567 VGNC:  25519 UniProt:  Q9TTS3 LinkDB All DBs Position 19:complement(13439554..13726306) Genome browser AA seq 2346 aa AA seqDB search MDEPSSLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL GDKIASSIVAQTAGIPTLPWSGSGLCVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKA AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSA GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET ESFQLNRIGTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV LTAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDV SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYA EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD MNTVLNYIFSHAQVTRKNLLVTMLIDQLCGRGPTLTDELLNILTELTQLSKTTNAKVALR ARQVLIASHLPSYELRLNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM SFSSNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLV EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA YGDKQGPLHGMLINTPYVTKDQLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQA FLPPPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPDGRDIIVI GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPID RVIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSVAE RKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST MDSPST NT seq 7041 nt NT seq  +upstreamnt  +downstreamnt atggatgaaccttcttccttggccaaacctctggagctgaaccagcactcccgattcatt attggctccgtgtctgaagataactcggaggatgagattagcaacctggtgaagctcgac ctgctggaggagaaggagggctctctgtcgccagcctcggtcagctcagacacgctctct gacttgggcatctcgagcctccaggatggtctggccttacacatgagatccagcatgtct ggcttgcacctagtcaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc actgtagcctctccagcagaatttgttactcgttttggtgggaataaagtgattgagaag gttctcattgccaacaatggcattgcagctgtgaaatgcatgagatccatccgccggtgg tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgtcatggtcacacctgaa gacctgaaagccaatgcagaatacattaagatggcggatcactacgtgcccgtgccagga ggccccaacaacaacaactatgcaaatgtggagttaattcttgacattgctaaaaggatc cccgtgcaagcagtttgggctggctggggtcatgcttctgagaatcccaagctcccagaa cttctcttgaaaaatggcatcgccttcatgggtcctccaagccaagccatgtgggctctg ggggataagatcgcatcttccatagtggctcaaactgctggtatcccaactcttccatgg agtggcagtggtctttgtgtggactggcacgaaaatgatttttcaaaacgaattttaaat gttcctcaggaactatatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggca gcggaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaggga atcagaaaagtcaacaatgcagatgacttccctaacctcttccgacaggttcaagctgaa gttcctgggtctcctatctttgtcatgagactagccaaacagtctcgtcatctggaggtg cagatcttagcagatcagtatggcaatgctatctctttgtttggtcgtgattgctctgtg caacgcaggcatcagaagattattgaagaagctcctgctgctattgctactccagcagta tttgaacatatggaacagtgtgcggtgaaacttgccaggatggttggttatgtgagtgcg gggactgtggaatacctctacagccaggatggcagcttctactttctggaactgaaccct cggctacaggtggagcacccctgtacagagatggtggccgatgtcaacctccctgctgcg cagctccagattgccatggggatccctctgtacagaatcaaggatatccgaatgatgtac ggggtctctccctggggcgatgctcccattgattttgaaaattcggctcacgttccttgc ccaaggggccatgttattgctgctcgtatcactagtgaaaatccagatgagggttttaag cccagctcaggaacagttcaagagctgaattttcgcagcaataagaacgtttggggttat ttcagtgttgctgctgcaggagggcttcatgaatttgctgattctcagtttggtcactgc ttttcctggggagaaaaccgagaggaagcaatttcaaacatggttgtggctttgaaggag ctgtctatccggggcgacttccggaccacagtcgagtacctgatcaaactgctggagact gaaagctttcagttgaacagaattggcacgggctggctggacagactgatagcagaaaaa gtacaggcggagcgacctgacaccatgctgggagttgtctgtggggctctccatgtggca gacgtgagcctgcggaatagcatctccaacttccttcactccttagagaggggtcaagtc ctcactgctcatacccttctgaatacagtagatgttgaacttatctacgagggagtgaag tatgtactgaaggtgactcgacagtccccgaactcctacgtggtgatcatgaacggctcg tgtgtggaagtagacgtgcatcgactgagcgacggtggactgctcttgtcctatgacgtc agcagttacaccacgtacatgaaggaggaggtggatagatatcgcatcacaattggcaat aaaacttgtgtgtttgagaaggaaaatgacccttcggtgctgcgctcaccctctgctggg aagttgatccagtacattgtggaggatggaggccacgtgtttgctggccagtgctatgcc gagatcgaggtgatgaagatggtaatgaccttaacagccgcagagtctggctgtatccat tatgtcaagcggcctggagcagctcttgacccgggctgtgtaatagccaaaatgcaactg gacaaccccagcaaggtccagcaggctgagcttcacacaggcagtctgccacggatccag agcacagcgctcagaggcgagaagctccaccgagtgttccactatgtcctggataatctg gtcaatgtgatgaatggatactgccttccagatcctttctttagcagcagggtgaaagac tgggttgaacggttgatgaagaccctcagagacccctccttgcctctcctagaattgcag gatatcatgactagcgtctctggtcgtatcccgcccaacgtggaaaagtctatcaagaag gaaatggctcagtatgccagcaacatcacatccgtgctctgtcagtttcccagccagcag attgccaacatcctagacagccacgcagccacactgaaccggaaatctgaacgggaagtc ttcttcatgaacactcagagcatcgtccagctggtgcagaggtaccgcagtggcatccga ggacacatgaaggctgtggtgatggacctgctgcggcagtacctgcgagtagagacacaa ttccagaacggtcactatgacaaatgcgtgttcgccctccgggaggagaacaagagtgat atgaacactgtgctgaactacatcttctctcatgctcaggtcaccaggaagaatcttctg gtcaccatgcttatcgatcagctgtgtggccggggccccaccctcactgatgagctgctg aatatcctcacggagctaactcaactcagcaagaccaccaacgcgaaggtggcgctccga gcacgccaggttcttattgcttcccatttgccatcctatgagcttcgcctcaaccaagtc gagtctatcttcctatccgccattgacatgtatggacaccagttctgcatcgagaacctg cagaaactcatcttgtccgaaacgtcgatttttgatgtcctaccaaacttcttctatcac agcaaccaggtcgtgaggatggcagctctggaggtgtatgttcgaagggcttatatcgcc tatgaacttaatagcgtacaacaccggcagctgaaggacaacacctgcgtggtggaattc cagttcatgctgcccacatcgcatccaaatagagggaacatccccacgctaaacagaatg tccttctcctccaacctcaaccactacggcatgactcacgtagccagtgtcagcgacgtg ctgctggacaacgcgttcactccgccgtgtcagcggatgggcgggatggtctcttttcgg acctttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgattcccca ccccaaagcccgacattccctgaggcaggtcacacgtctctgtatgacgaagacaaggtc cccagggatgaaccaattcacattttgaatgtggctatcaaaacagactgtgacatcgag gatgacagtctagcagctatgttccgagagtttacccagcaaaacaaagctaccctggtt gaacatgggatccgacgccttactttcctggttgcacaaaaggatttcaggaaacaagtc aactatgaagtggatcagagatttcatagagaatttcctaaatttttcacgttccgagca agggataagtttgaggaagatcgtatctatcgtcacctggagcctgccctagctttccag ttagagctgaaccggatgagaaattttgaccttactgccatcccgtgtgccaatcacaag atgcacttgtatcttggggcagccaaggtagaagtgggcacagaagtgacagactacagg ttctttgttcgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcctttgaa tatctacaaaatgaaggggagcggctcctcctggaagccatggatgagttggaagtcgcc tttaacaatacaaatgtccggactgactgcaaccacatcttcctcaactttgttcctaca gtcatcatggacccatcgaagattgaggaatccgtgcggagcatggtgatgcgctatgga agtcggctgtggaagctgcgtgtcctccaggcagaactgaaaatcaacattcgcctgaca ccaactggaaaagcaattcccatccgcctcttcctgacgaacgagtctggctattacttg gacatcagcctgtacaaggaagtgactgattccaggacagcacagatcatgtttcaggca tatggagacaaacagggaccattacatggaatgttaatcaacactccgtacgtgaccaaa gaccagcttcaatccaagaggttccaggcacagtccttagggacaacatacatatatgac atcccagaaatgtttcggcagtccctgatcaaactctgggaatctatgtcctcccaagca ttccttccaccgccccctctgccttcagacatactgacgtacactgagctcgtgttggat gatcaaggtcaactggttcacatgaacaggcttccaggaggaaatgagattggcatggta gcttggaaaatgacccttaaaagtccagaatatccagacggccgagatatcattgttatt ggcaatgacatcacttaccgaattgggtcctttggaccccaagaggatttgctgtttctc agagcttctgagcttgccagggcagagggcatcccacgcatctatgtagcagccaacagt ggagcaagaattggactggcagaggaaattcgtcatatgtttcacgtggcctgggtagat cctgaggatccttacaagggatacaaatatttatatctgacccctcaagattacaagaga gtcagtgctctcaactctgtccattgtgaacatgtggaagatgaaggagaatccaggtac aagatcactgacattattgggaaggaagaaggacttggagcagagaaccttcgagggtct ggaatgattgctggggaatcctcgttggcctacgacgagatcatcaccatcagcctggtt acatgcagggccattgggattggggcttacctcgtccgactgggacagagaaccatccag gtcgaaaattctcacttaatcctgacaggagctggggccctcaacaaagtcctcggtagg gaagtatacacctccaacaaccagctggggggcatccagatcatgcacaacaatggggtg acgcacagcaccgtctgtgacgacttcgagggggtgttcaccgtcctgcactggctgtct tacatgccgaagagtgtatacagttcagttcctctcctgaactccaaggatccaatagac agagtcatcgagtttgtgcccacgaaggcgccgtatgaccctcggtggatgctggcaggc cggcctcacccaacccagaaaggtcagtggttgagtggattttttgactatggctctttc tcagagatcatgcaaccgtgggcacagactgtggtggttggcagagccaggctaggagga atacccgtgggagtagttgccgtagaaacccgaacagtggagctgagcatcccggctgat cctgcaaacctggattctgaagccaagattatccagcaggctggccaggtttggttccca gactccgcgtttaagacgtatcaggccattaaggacttcaaccgtgaagggctgcctctg atggtctttgccaactggagaggcttctccggtgggatgaaagatatgtacgaccaggtg ctgaagttcggcgcttacatcgtggacggcttacgggagtgctcgcagcccgtgatggtc tacatcccgcctcaggccgagctccgaggcggctcctgggtggtgattgaccccaccatc aacccgcggcacatggagatgtatgcggaccgcgagagcaggggatccgttctggagccg gaagggacagtcgaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtg gacccagtctacatccacttggctgagcgattgggtacccccgagctcagcgtggccgag cggaaggagctggagagcaagctgaaggagcgagaggagttcctccttcccatctaccac caggtggccgtgcagtttgcagacctgcacgacaccccgggccgcatgcaggagaagggg gtcattaacgacatcctggattggaagacttcacgcaccttcttctactggcggctgagg cggctgttgctggaggacctggtcaagaagaaaatccacaatgccaatcccgagctgaca gacggccagatccaggccatgctaaggcgctggtttgtggaggtggagggaaccgtgaag gcctatgtctgggacaacaacaaggatctggtggagtggctggagaaacagctcacagag gaagacggcgtccgctcggtgattgaagagaacatcaagtacatcagcagagactacgtc ctcaagcagatccgcagcttggtccaggccaacccagaggttgccatggattccatcgtc cacatgacgcagcacatctcgcccacccagcgagcagaagtcgttcggatcctctcgacg atggactcgccctcaacgtag

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