Bos taurus (cow): 281801
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Entry
281801 CDS
T01008
Symbol
GRK5
Name
(RefSeq) G protein-coupled receptor kinase 5
KO
K08291
G protein-coupled receptor kinase [EC:
2.7.11.16
]
Organism
bta
Bos taurus (cow)
Pathway
bta04062
Chemokine signaling pathway
bta04144
Endocytosis
bta05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
281801 (GRK5)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
281801 (GRK5)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
281801 (GRK5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
281801 (GRK5)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.16 G-protein-coupled receptor kinase
281801 (GRK5)
Protein kinases [BR:
bta01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
281801 (GRK5)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
Kinase-like
Pkinase_fungal
Sulfakinin
Motif
Other DBs
NCBI-GeneID:
281801
NCBI-ProteinID:
NP_776756
Ensembl:
ENSBTAG00000007981
VGNC:
29656
UniProt:
P43249
Structure
PDB
PDBj
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Position
26:39360272..39588332
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AA seq
590 aa
AA seq
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MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHINQCEDLRRTIDRDYCSLCDKQ
PVGRLLFRQFCETRPGLESYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFITQ
VGRDLVSQTEEKLLQKPCKELFSACVQSVHDYLRGEPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSRFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHHENIVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDHTDDDFYSKFSTGSVPIPWQSEMIETECFKELNVFGPHGTLSPDLNRS
HPPEPPKKGLLQRLFKRQHQNNSKSSPNSKTSFNHHINSNHVSSNSTGSS
NT seq
1773 nt
NT seq
+upstream
nt +downstream
nt
atggagctggaaaacatcgtggccaacacggtcttgctgaaagccagggaaggaggcgga
ggaaagcgcaaagggaaaagcaagaagtggaaggaaatcctgaagttccctcacataaac
cagtgtgaagacctccgaagaaccatagaccgagattactgcagtttatgtgacaaacag
ccagtcgggaggctgcttttccggcagttctgcgaaaccagacctgggctggagtcctac
attcagttcctggactcggtggcagaatatgaagttactccagatgaaaaactgggagaa
aaagggaaggaaattatgaccaagtacctcaccccaaagtccccagttttcatcacccaa
gttggacgggacctggtctcccagacggaggagaagctccttcagaaaccctgcaaagaa
ctcttctcggcctgcgtgcagtctgtccacgactacctgaggggagaacccttccacgag
tacctggacagcatgtattttgatcgctttctccagtggaagtggttggaaaggcaaccg
gtaaccaaaaacactttcaggcagtaccgagtactaggaaaagggggctttggggaggtc
tgtgcctgccaggttcgggccacgggtaaaatgtacgcctgcaaacgcttggagaagaag
aggatcaaaaagaggaaaggggagtccatggccctgaatgagaagcagattctggagaag
gtcaacagtcggtttgtggtcaacctggcctacgcctacgagaccaaggatgccctgtgt
ttggtcctgaccatcatgaacggcggggacctgaagttccacatttacaacatggggaac
cccggcttcgaggaggagcgcgccctgttctacgcggcagagatcctgtgcggcctggag
gacctccaccatgagaacattgtctacagagatttgaaacctgaaaatatcctgttagac
gattacggccacattagaatttcggacctgggcctggccgtgaagatccccgagggagac
ctgattcgcggccgagtgggcaccgttggctacatggctccagaggtcctgaacaaccag
aggtatggcctgagccccgactactggggtctgggctgcctcatctacgagatgatcgag
ggccagtcgcccttccgcggccgcaaggagaaggtgaagcgggaggaggtggaccgccgg
gtgttggagacagaggaggtgtactcgcacaagttctccgaggaggccaagtccatctgc
aaaatgctgctcaccaaagatgcaaagcagaggctgggctgccaggaggaaggggccgcg
gaggtcaagagacaccccttcttcaggaacatgaatttcaagcgcttagaggccgggatg
ttggatcccccctttgttccagatccccgggccgtgtactgcaaggacgtcttggacatc
gagcagttctccaccgtgaagggcgtcaacctggaccacacggacgacgacttctactcc
aagttctccacgggctctgtgcccatcccgtggcaaagcgagatgatagaaacagagtgc
tttaaggagctgaacgtgttcggaccccacggtaccctctcaccggacctgaaccgaagc
caccctccggaaccgccaaagaaagggctgctccagaggctcttcaagcgtcagcatcaa
aacaattccaagagttcacccaattccaagaccagttttaaccaccacatcaattcaaac
cacgtgagttcaaactccaccggaagcagctag
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