Bos taurus (cow): 281971
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Entry
281971 CDS
T01008
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform PDE2A1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
bta
Bos taurus (cow)
Pathway
bta00230
Purine metabolism
bta01100
Metabolic pathways
bta04022
cGMP-PKG signaling pathway
bta04740
Olfactory transduction
bta04925
Aldosterone synthesis and secretion
bta05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
281971 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
281971 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
281971 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
281971 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
281971 (PDE2A)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
281971 (PDE2A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Methyltrans_Mon_3rd
Motif
Other DBs
NCBI-GeneID:
281971
NCBI-ProteinID:
NP_001243202
BGD-bta:
BT26532
Ensembl:
ENSBTAG00000008419
VGNC:
32674
UniProt:
P14099
Structure
PDB
PDBj
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All DBs
Position
15
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AA seq
921 aa
AA seq
DB search
MRRQPAASRDLFAQEPVPPGSGDGALQDALLSLGSVIDVAGLQQAVKEALSAVLPKVETV
YTYLLDGESRLVCEEPPHELPQEGKVREAVISRKRLGCNGLGPSDLPGKPLARLVAPLAP
DTQVLVIPLVDKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALKRVQALQQRESSV
APEATQNPPEEAAGDQKGGVAYTNQDRKILQLCGELYDLDASSLQLKVLQYLQQETQASR
CCLLLVSEDNLQLSCKVIGDKVLEEEISFPLTTGRLGQVVEDKKSIQLKDLTSEDMQQLQ
SMLGCEVQAMLCVPVISRATDQVVALACAFNKLGGDLFTDQDEHVIQHCFHYTSTVLTST
LAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNEL
VAKVFDGGVVEDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTR
NILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEA
QYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAIL
SMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNY
LEDMEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNT
HGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRTNKQHHSLLL
CLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQI
SFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEY
EVPDLDGARAPINGCCSLDAE
NT seq
2766 nt
NT seq
+upstream
nt +downstream
nt
atgcgccgacagcctgcagccagccgggacctctttgcacaggagccagtgcccccaggg
agtggagacggcgcattgcaggatgctttgctgagcctgggctccgtcatcgacgttgca
ggcttgcaacaggctgtcaaggaggccctgtcggctgtgcttcccaaagtggagacggtc
tacacctacctgctggatggggaatcccggctggtgtgtgaggagcccccccacgagctg
ccccaggaggggaaagtgcgagaggctgtgatctcccggaagcggctgggctgcaatgga
ctgggcccctcagacctgcctgggaagcccttggcaaggctggtggctccactggctcct
gacacccaagtgctggtcataccgctggtggacaaggaggccggggctgtggcagctgtc
atcttggtgcactgtggtcagctgagtgacaatgaggagtggagcctgcaagctgtggag
aagcataccctggtggccctgaaaagggtgcaggccttgcagcagcgcgagtccagcgtg
gccccggaagcgacccagaatcctccggaggaggcagcgggagaccagaagggtggggtc
gcatacacaaaccaagaccgaaagatcctgcagctttgcggggagctctacgacctggat
gcatcttccctgcagctcaaagtcctccaatatctgcaacaggagacccaggcatcccgc
tgctgcctgctgctggtatccgaggacaatcttcagctctcctgcaaggtcattggagat
aaagtactggaggaagagatcagctttccgttgaccacaggacgcctgggccaagtggtg
gaagacaagaagtctatccagctgaaagatctcacctccgaggatatgcaacagctgcaa
agcatgttgggctgtgaggtgcaggccatgctctgtgtccctgtcatcagccgggccact
gaccaggtcgtggccctggcctgtgccttcaacaagctcggaggagacttgttcacagac
caggacgagcacgtgatccagcactgcttccactacaccagcacagtgctcaccagcacc
ctggccttccagaaggagcagaagctcaagtgtgagtgccaggctcttctccaagtggcg
aagaacctcttcactcatctggatgacgtctccgtgctgctccaggagatcatcacagag
gccaggaacctcagcaatgctgagatctgctctgtgttcctgctggatcagaacgagctg
gtggccaaggtgttcgatgggggtgtggtggaagatgagagctatgagatccgcattccc
gctgaccagggcatcgcgggtcatgtggcgaccaccggccagatcctaaacatcccagat
gcttacgcacatccgcttttctaccgaggcgtggacgacagcaccggcttccggacgcgc
aacatcctctgcttccccatcaagaacgagaaccaggaggtcatcggtgtggccgagctg
gtgaacaagatcaatggaccatggttcagcaagtttgatgaagacctggctacagccttc
tccatctactgtggcatcagcattgcccattccctcctatacaagaaagtgaatgaggcg
cagtatcgcagccaccttgccaatgagatgatgatgtaccacatgaaggtctctgatgac
gagtacaccaaacttctccatgacgggatccagcctgtggctgccatcgactccaacttt
gccagtttcacatacactcctcgctctctgcccgaggatgacacttccatggccatcctg
agcatgctgcaggacatgaatttcatcaataactacaaaattgactgcccgacactggcc
cggttctgtttgatggtgaagaagggctaccgggatcccccctaccacaactggatgcac
gccttttctgtctcccacttctgctacctgctctacaagaacctggagctcaccaactac
ctcgaggacatggagatctttgccttgtttatttcctgcatgtgtcacgacctggaccac
agaggcacaaacaactccttccaggtggcctcgaaatctgtgctggccgcgctctacagc
tcggaaggctctgtcatggagaggcaccacttcgctcaggccattgccatcctcaacacc
cacggctgcaacatctttgaccacttctcccggaaggattatcagcgcatgttggacctg
atgcgggacatcatcttggccacagatctggcccaccacctccgcatcttcaaggacctc
caaaagatggccgaagtgggctatgatcgaaccaacaagcagcaccacagcctccttctc
tgcctccttatgacctcctgtgacctctctgaccagaccaagggctggaagaccacgagg
aagatcgcggagctgatctacaaagagttcttctcccagggagacttggagaaggccatg
ggcaacaggccgatggagatgatggaccgtgagaaggcctacatccccgagctgcagatc
agcttcatggagcacatcgcaatgcccatctacaagctgctgcaagacctgttccccaag
gcggccgagttgtacgaacgcgtggcctctaatcgtgagcactggaccaaggtgtcacac
aagttcaccatccgaggcctcccgagcaacaactcgttggacttcctggacgaggagtat
gaggtgcctgacctggatggcgctagggctcccatcaatggctgttgcagccttgatgct
gagtga
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