Bos taurus (cow): 282097
Help
Entry
282097 CDS
T01008
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X3
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
bta
Bos taurus (cow)
Pathway
bta01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
282097 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
bta03032
]
282097 (TOP2B)
03036 Chromosome and associated proteins [BR:
bta03036
]
282097 (TOP2B)
Enzymes [BR:
bta01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
282097 (TOP2B)
DNA replication proteins [BR:
bta03032
]
Eukaryotic type
DNA Topoisomerases
282097 (TOP2B)
Chromosome and associated proteins [BR:
bta03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
282097 (TOP2B)
Centrosome formation proteins
Centriole proteins
282097 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
282097
NCBI-ProteinID:
XP_024842148
BGD-bta:
BT27563
Ensembl:
ENSBTAG00000004593
VGNC:
49158
LinkDB
All DBs
Position
27:40133486..40196656
Genome browser
AA seq
1614 aa
AA seq
DB search
MAKAGGGGGGAGAGGHGALTWVNNAAKKEESEIANKNDSSKKLSVERVYQKKTQLEHILL
RPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCI
KVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGY
GAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSK
FKMEKLDRDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVA
LKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKN
KAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNC
GIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSA
KSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDA
ESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQ
ELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPED
DAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELIL
FSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALM
MTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNL
LKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDP
HPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLN
GTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDH
MGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITI
ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEESQNQHDDSSSDSGTPSGPDFNYI
LNMSLWSLTKEKVEELIKQRDAKGREVSDLKRKSPSDLWKEDLAAFVEELDKVEAQERED
VLAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRVVPEITAMKADASKKLLKKRKGDLD
ATAVRVDFDEELSGAAVEGGEEAPIPSAPVHRGPKPKREKKEPGTRVRKTPTSSGKPSAK
KVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEDDADDDDD
NNDLEELKVKASPIANDGEEEFVPSDGLDKDEYTFSPGKSKAAPEKSSHDKKSQDFGTLF
SFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTEKVPSKTVAAKKGKPSLDTASKPK
RAPKQKKVETVNSDSDSEFGVPKKTAPKGKGRGAKKRKASGSENEGDYNPGRKTSKPPSK
KPKKTSFDEDSDVDLFPSDLTTEPPSLPRTGRARKEVKYFADSDEEDVDFAMFN
NT seq
4845 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcggcgcgggagctggcggccacggggcgctgacc
tgggtgaacaatgctgcaaaaaaggaagagtcagaaattgcaaacaaaaatgattcttca
aagaagttgtccgtcgagagagtgtatcagaaaaagacacaactcgaacatattctgctt
cgtcctgatacgtacattgggtcagtggagccattgacacagctcatgtgggtatatgat
gaagatgtaggaatgaattgcagagaggttacctttgtgccgggtttatataagatcttt
gatgaaattttggttaatgcagctgataataaacagagggataagaacatgacctgtatt
aaagtttctattgatcctgaatctaacataataagcatttggaataatgggaaaggcatt
ccagtagtagaacacaaagtagagaaagtttatgttcctgcattaatttttggacagctt
ttaacgtccagtaactatgacgatgatgagaaaaaagtaacaggtggtcgcaatggttat
ggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgcttgcaaagaa
tacaaacatagttttaagcagacatggatgaataatatgatgaagacttctgaagccaaa
attaaacattttgatggtgaagattacacatgtataacattccaaccagatctgtccaaa
tttaagatggagaagcttgacagggatattgttgctctcatgaccagaagagcttatgat
ttggctggttcctgcaagggagtcaaggtcatgtttaatggaaagaaattgccggtaaat
ggatttcgcagttatgtagatctttatgtgaaagacaaattggatgaaacgggagtggct
ctaaaagttattcatgaacttgcaaatgaaagatgggacgtttgtctcactttgagtgaa
aaaggattccagcaaatcagctttgtaaatagcattgcaacaacaaaaggtggacggcat
gtggattacgtagtagaccaagttgttggtaaactgattgaagtagttaagaaaaagaac
aaagctggtgtgtcagtgaaaccatttcaagtaaaaaatcatatatgggtttttattaac
tgccttattgaaaatccaacttttgattctcaaactaaggaaaacatgactttgcagccc
aaaagttttggatccaaatgccaactatcagaaaaattttttaaagcagcctctaactgt
ggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagacacagctgaacaag
aagtgttcatcagtaaagtacagtaaaatcaaaggtattcccaaattggatgatgctaat
gatgctggtggcaaacattccctggagtgcacactgatcctgacagaaggagactctgcc
aagtccctggccgtgtctggattaggcgtcattgggagggacagatatggggtctttccc
ctcaggggaaagattcttaacgtgcgggaagcttctcacaaacagatcatggaaaatgca
gaaataaacaatattattaaaatagttggtctacaatataagaaaagttatgatgatgca
gaatctctgaaaactttacgctatggaaagattatgattatgactgatcaggatcaagat
ggttctcacataaaaggcctgcttattaatttcatccatcacaattggccatcacttttg
aagcatggttttcttgaagagttcattacccctattgtaaaggctagcaaaaataagcag
gaactttccttctacagtattcctgaatttgatgagtggaaaaaacatatagaaaaccag
aaagcctggaaaataaaatactacaaagggttgggtaccagtacagctaaggaagccaag
gaatattttgctgatatggaaaggcaccgtatcttatttagatatgctggtcctgaagat
gatgctgccattaccttggcattcagtaagaagaagatcgatgacagaaaagaatggtta
acgaactttatggaagatcggagacagcgtaggttacatggcttaccagagcaattctta
tatggtacagcaaccaagcatttgacttataatgattttatcaacaaggaattgattctc
ttctcaaactcagacaatgaaagatctataccatctcttgttgatggttttaaaccaggt
caacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaagtgaaagttgca
cagttggctggatctgttgccgagatgtctgcttatcatcatggagaacaagcattgatg
atgactattgtgaacttggctcagaactttgtggggagcaacaacatcaacttgcttcag
cctattggtcagtttggaactcgacttcacgggggcaaagatgctgcgagccctcgttat
attttcacaatgttgagcactttagcaagactgctttttcctgctgtggatgacaacctg
cttaaattcctttatgatgataatcagcgtgtggagcctgagtggtatattcccataatt
ccaatggttttaataaatggtgctgagggcattggcacagggtgggcttgtaagctgccc
aactacgatgccagagagattgtgaacaatgtcaggcgaatgctcgatggcctggatcct
catcccatgcttccaaactacaaaaactttaaaggaacgatccaagaacttggtcaaaac
cagtatgcagtcagtggtgagatatttgtggtggatagaaacacggtggagattaccgag
ctccccgtcagaacttggacacaggtatacaaagaacaggttttagaacctatgctaaat
ggaacagataaaacaccagcattaatttctgattataaagaatatcatactgatacaact
gtgaaatttgtagtgaaaatgactgaagagaagctagcacaagcagaagctgctggattg
cacaaagtttttaaacttcaaactactcttacttgtaattccatggtactctttgatcat
atgggatgtctgaagaagtatgaaactgtgcaagatattttgaaagaattctttgattta
cgattaagctattatggtttacgaaaggagtggcttgtaggaatgttgggagcagaatct
actaagcttaataatcaagcccgtttcattttagagaagatacaagggaaaatcactata
gagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatctgac
ccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaatcacaaaac
cagcatgatgatagttcctctgattcaggaactccttcaggccctgattttaattatatt
ttaaatatgtctctatggtctcttactaaagaaaaagttgaagaactgattaaacagaga
gatgcaaaagggcgagaggtcagtgatcttaaaaggaaatctccttcagatctttggaaa
gaagatttagcagcttttgttgaagaactggataaagtggaagcgcaggaacgagaagac
gttctggccgggatggccggaaaagcaatcaaggggaaggttggcaaacctaaggtgaag
aagcttcagctagaagagacgatgccctccccttacggcaggagagtggttcctgagatc
actgccatgaaggcagatgccagcaagaagctgctgaagaagagaaagggcgatctggat
gccacagcagtccgagtggactttgatgaagagctcagcggagcagcagtggaaggtggg
gaagaggcgccgatcccgtcagctcctgtacacagaggccccaaacccaaaagggagaaa
aaagagcctggtaccagggtgagaaaaacacctacatcatctggtaaaccgagtgcaaag
aaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagtgacttggaa
gaaacagaacctgtggttattccaagagactctttacttaggagagcggctgctgaacgg
ccaaagtatacattcgatttctcggaagaggaggaagatgacgccgatgatgatgacgac
aataatgacttagaggagctgaaggtcaaagcatctcccatagcaaatgatggagaagag
gagtttgtcccctcagatggcctagataaagatgaatacacattctcaccaggcaaatcg
aaagctgctccagaaaagtcttcccatgacaagaagagtcaggattttgggactctcttc
tcttttccttcatactctcagaagtcagaagatgattcagctaaatttgacagtaatgaa
gaagattctgcttctgtattttcaccatcatttggtctgaagcaaacagaaaaagttcca
agtaaaacagtagctgctaaaaagggaaaaccgtctttagatacagcctctaagcccaag
agggcccccaaacagaagaaagtagagactgtgaactctgactcggattctgaattcggc
gttccaaagaaaacagcaccgaaaggtaaaggccgaggggcaaagaaaaggaaagcatct
ggctctgaaaacgaaggtgattacaatcctggcaggaaaacctccaaaccaccaagcaag
aagccgaagaaaacctcttttgatgaggactcagatgtggacctcttcccctcagacctc
accaccgagccaccgtcactgccgcggactggccgggcaaggaaagaagtaaaatatttt
gcagactctgacgaggaagatgtcgattttgcgatgtttaattaa
DBGET
integrated database retrieval system
