Bos taurus (cow): 282149
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Entry
282149 CDS
T01008
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
bta
Bos taurus (cow)
Pathway
bta00280
Valine, leucine and isoleucine degradation
bta00640
Propanoate metabolism
bta00785
Lipoic acid metabolism
bta01100
Metabolic pathways
bta01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
282149 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
282149 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
282149 (BCKDHA)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
282149 (BCKDHA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
282149
NCBI-ProteinID:
NP_776931
BGD-bta:
BT12097
Ensembl:
ENSBTAG00000016037
VGNC:
108964
UniProt:
P11178
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Position
18:50541524..50560679
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AA seq
455 aa
AA seq
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MQGSAKMAMAVAVAVARVWRPSRGLGRTGLPLLRLLGARGLARFHPHRWQQQQHFSSLDD
KPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMT
LLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLVFGQYREAGVLMYRDYP
LELFMAQCYGNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANR
VVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPG
YGILSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDE
VNYWDKQDHPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLIFS
DVYQEMPAQLRKQQESLARHLQTYGEHYPLDHFEK
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgcaggggtcagccaagatggcgatggcggtggcggttgcggtggccagggtttggaga
ccaagtcgaggcttgggacggacgggcctcccgctcctgcggctgcttggggctcgtggg
ctggctagatttcacccccacaggtggcagcaacagcagcacttctcgtccctggatgac
aagccgcagttcccaggggcctcagcggagttcatagacaagctcgaattcatccagccc
aatgtcatctctgggatccccatctaccgggtcatggaccggcagggccagatcatcaac
cccagcgaggatccccacctgccccaggagaaggtgctcaaattctacaagagcatgacc
ctgctcaacaccatggaccgcatcctctatgaatcccagaggcagggccgcatatccttc
tacatgaccaactatggcgaagaggggacacacgtggggagcgcagcagccctggacgac
acagacctggtgtttggccagtaccgggaggcaggtgtgctcatgtaccgggactacccg
ttggagctgttcatggcccagtgctacggcaacgtgagcgacctgggcaaggggcgccag
atgcccgtccactacggctgcagggagcgtcacttcgtcaccatctcctctccactggcc
acgcagatcccccaggcggtcggggcagcctacgcggccaagagggccaacgctaacagg
gtggtcatctgttactttggagagggggcggccagtgagggggacgcccacgccggcttc
aacttcgccgccaccctcgagtgccccatcatcttcttctgtcggaacaacggctacgcc
atctccacgcccacctcggagcagtaccgcggggacggcatagcggctcgaggccccggg
tacggcatcctgtccatccgcgtggacggcaatgatgtgtttgccgtgtacaacgccacc
aaggaggcccggcggcgggccgtggcggagaaccagcccttcctcattgaggccatgacc
tacaggatcgggcaccacagcaccagtgacgacagctcggcgtaccgctcagtggacgag
gtcaactactgggacaagcaggaccaccccatctcccggctgcggcatcacctgcagagc
cgcggctggtgggacgacgagcaggagaaggcctggaggaagcagtcccgcaagaaggta
atggaggcctttgagcaggctgagcggaagctgaagcccaaccccagcttgatcttctcg
gacgtgtatcaggagatgcctgcccagctccgcaagcagcaggagtctctggcacgtcac
ctccagacctatggtgaacactacccgctggaccacttcgagaagtga
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