Bos taurus (cow): 282325 Help Entry 282325            CDS       T01008                                  Symbol PRKCB Name (RefSeq) protein kinase C beta type   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism bta  Bos taurus (cow) Pathway bta01521   EGFR tyrosine kinase inhibitor resistance bta04010   MAPK signaling pathway bta04012   ErbB signaling pathway bta04014   Ras signaling pathway bta04015   Rap1 signaling pathway bta04020   Calcium signaling pathway bta04062   Chemokine signaling pathway bta04064   NF-kappa B signaling pathway bta04066   HIF-1 signaling pathway bta04070   Phosphatidylinositol signaling system bta04071   Sphingolipid signaling pathway bta04082   Neuroactive ligand signaling bta04150   mTOR signaling pathway bta04270   Vascular smooth muscle contraction bta04310   Wnt signaling pathway bta04370   VEGF signaling pathway bta04510   Focal adhesion bta04540   Gap junction bta04613   Neutrophil extracellular trap formation bta04650   Natural killer cell mediated cytotoxicity bta04662   B cell receptor signaling pathway bta04666   Fc gamma R-mediated phagocytosis bta04670   Leukocyte transendothelial migration bta04713   Circadian entrainment bta04720   Long-term potentiation bta04723   Retrograde endocannabinoid signaling bta04724   Glutamatergic synapse bta04725   Cholinergic synapse bta04726   Serotonergic synapse bta04727   GABAergic synapse bta04728   Dopaminergic synapse bta04730   Long-term depression bta04750   Inflammatory mediator regulation of TRP channels bta04911   Insulin secretion bta04912   GnRH signaling pathway bta04916   Melanogenesis bta04918   Thyroid hormone synthesis bta04919   Thyroid hormone signaling pathway bta04921   Oxytocin signaling pathway bta04925   Aldosterone synthesis and secretion bta04928   Parathyroid hormone synthesis, secretion and action bta04929   GnRH secretion bta04931   Insulin resistance bta04933   AGE-RAGE signaling pathway in diabetic complications bta04935   Growth hormone synthesis, secretion and action bta04960   Aldosterone-regulated sodium reabsorption bta04961   Endocrine and other factor-regulated calcium reabsorption bta04970   Salivary secretion bta04971   Gastric acid secretion bta04972   Pancreatic secretion bta04973   Carbohydrate digestion and absorption bta05017   Spinocerebellar ataxia bta05022   Pathways of neurodegeneration - multiple diseases bta05031   Amphetamine addiction bta05032   Morphine addiction bta05140   Leishmaniasis bta05143   African trypanosomiasis bta05146   Amoebiasis bta05161   Hepatitis B bta05163   Human cytomegalovirus infection bta05164   Influenza A bta05170   Human immunodeficiency virus 1 infection bta05171   Coronavirus disease - COVID-19 bta05200   Pathways in cancer bta05205   Proteoglycans in cancer bta05206   MicroRNAs in cancer bta05207   Chemical carcinogenesis - receptor activation bta05214   Glioma bta05223   Non-small cell lung cancer bta05225   Hepatocellular carcinoma bta05231   Choline metabolism in cancer bta05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:bta00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     282325 (PRKCB)    04012 ErbB signaling pathway     282325 (PRKCB)    04014 Ras signaling pathway     282325 (PRKCB)    04015 Rap1 signaling pathway     282325 (PRKCB)    04310 Wnt signaling pathway     282325 (PRKCB)    04370 VEGF signaling pathway     282325 (PRKCB)    04064 NF-kappa B signaling pathway     282325 (PRKCB)    04066 HIF-1 signaling pathway     282325 (PRKCB)    04020 Calcium signaling pathway     282325 (PRKCB)    04070 Phosphatidylinositol signaling system     282325 (PRKCB)    04071 Sphingolipid signaling pathway     282325 (PRKCB)    04150 mTOR signaling pathway     282325 (PRKCB)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     282325 (PRKCB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     282325 (PRKCB)    04540 Gap junction     282325 (PRKCB)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     282325 (PRKCB)    04650 Natural killer cell mediated cytotoxicity     282325 (PRKCB)    04662 B cell receptor signaling pathway     282325 (PRKCB)    04666 Fc gamma R-mediated phagocytosis     282325 (PRKCB)    04670 Leukocyte transendothelial migration     282325 (PRKCB)    04062 Chemokine signaling pathway     282325 (PRKCB)   09152 Endocrine system    04911 Insulin secretion     282325 (PRKCB)    04929 GnRH secretion     282325 (PRKCB)    04912 GnRH signaling pathway     282325 (PRKCB)    04921 Oxytocin signaling pathway     282325 (PRKCB)    04935 Growth hormone synthesis, secretion and action     282325 (PRKCB)    04918 Thyroid hormone synthesis     282325 (PRKCB)    04919 Thyroid hormone signaling pathway     282325 (PRKCB)    04928 Parathyroid hormone synthesis, secretion and action     282325 (PRKCB)    04916 Melanogenesis     282325 (PRKCB)    04925 Aldosterone synthesis and secretion     282325 (PRKCB)   09153 Circulatory system    04270 Vascular smooth muscle contraction     282325 (PRKCB)   09154 Digestive system    04970 Salivary secretion     282325 (PRKCB)    04971 Gastric acid secretion     282325 (PRKCB)    04972 Pancreatic secretion     282325 (PRKCB)    04973 Carbohydrate digestion and absorption     282325 (PRKCB)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     282325 (PRKCB)    04961 Endocrine and other factor-regulated calcium reabsorption     282325 (PRKCB)   09156 Nervous system    04724 Glutamatergic synapse     282325 (PRKCB)    04727 GABAergic synapse     282325 (PRKCB)    04725 Cholinergic synapse     282325 (PRKCB)    04728 Dopaminergic synapse     282325 (PRKCB)    04726 Serotonergic synapse     282325 (PRKCB)    04720 Long-term potentiation     282325 (PRKCB)    04730 Long-term depression     282325 (PRKCB)    04723 Retrograde endocannabinoid signaling     282325 (PRKCB)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     282325 (PRKCB)   09159 Environmental adaptation    04713 Circadian entrainment     282325 (PRKCB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     282325 (PRKCB)    05206 MicroRNAs in cancer     282325 (PRKCB)    05205 Proteoglycans in cancer     282325 (PRKCB)    05207 Chemical carcinogenesis - receptor activation     282325 (PRKCB)    05231 Choline metabolism in cancer     282325 (PRKCB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     282325 (PRKCB)    05214 Glioma     282325 (PRKCB)    05223 Non-small cell lung cancer     282325 (PRKCB)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     282325 (PRKCB)    05161 Hepatitis B     282325 (PRKCB)    05171 Coronavirus disease - COVID-19     282325 (PRKCB)    05164 Influenza A     282325 (PRKCB)    05163 Human cytomegalovirus infection     282325 (PRKCB)   09174 Infectious disease: parasitic    05146 Amoebiasis     282325 (PRKCB)    05140 Leishmaniasis     282325 (PRKCB)    05143 African trypanosomiasis     282325 (PRKCB)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     282325 (PRKCB)    05022 Pathways of neurodegeneration - multiple diseases     282325 (PRKCB)   09165 Substance dependence    05031 Amphetamine addiction     282325 (PRKCB)    05032 Morphine addiction     282325 (PRKCB)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     282325 (PRKCB)   09167 Endocrine and metabolic disease    04931 Insulin resistance     282325 (PRKCB)    04933 AGE-RAGE signaling pathway in diabetic complications     282325 (PRKCB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     282325 (PRKCB)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:bta01001]     282325 (PRKCB) Enzymes [BR:bta01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      282325 (PRKCB) Protein kinases [BR:bta01001]  Serine/threonine kinases: AGC group   PKC family [OT]    282325 (PRKCB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C Kinase-like ABC1 CEP76-C2 Motif Other DBs NCBI-GeneID:  282325 NCBI-ProteinID:  NP_777012 BGD-bta:  BT10706 Ensembl:  ENSBTAG00000020921 VGNC:  33328 UniProt:  P05126 LinkDB All DBs Position 25:21505317..21880937 Genome browser AA seq 673 aa AA seqDB search MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE LRQKFERAKIGPGPKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLITKHPGKRLGCGPEGERDIKEHAFF RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS FVNSEFLKPEVKS NT seq 2022 nt NT seq  +upstreamnt  +downstreamnt atggctgacccggccgcggggccgccgccgagcgagggagaggagagcaccgtgcgcttc gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc gggaagcaaggatttcagtgccaagtctgctgttttgtcgtgcacaagcggtgccatgaa tttgtcaccttctcctgcccgggcgctgacaagggcccagcctctgacgacccccggagc aaacacaagttcaagatccacacatactccagccccacgttttgtgaccactgtgggtca ttgctctatggacttatccaccaggggatgaaatgtgacacctgcatgatgaacgtccac aagcgctgcgtgatgaacgtccccagcctctgcggcacggaccacacggagcgccgcggc cgcatctacatccaagcccacatcgagagggaggtcctcattgttgtcgtaagagatgct aaaaaccttgtacctatggatcctaatggcttgtcagatccttacgtgaaactgaaactg attcctgatcccaagagtgagagcaagcagaagaccaagaccatcaagtgctccctcaac cccgagtggaacgaaacatttagattccagctgaaagaatcggacaaagacaggagactg tctgtagagatttgggattgggatctgaccagcagaaatgacttcatgggatctttgtcg tttgggatttctgaactgcagaaagctggtgttgatggctggtttaagttactgagccag gaggaaggcgagtacttcaacgtgcccgtgccaccggaaggcagtgagggcaacgaggaa ctgcgacagaaattcgagagagccaagatcggtcctgggcccaagactcctgaagaaaag acgaccaacaccatctccaaatttgacaacaacggcaacagggaccggatgaaattgacc gattttaacttcctgatggtgctgggaaaaggcagctttggcaaggtcatgctctcagag cgaaaaggcacagatgagctgtatgctgtgaagatcctgaaaaaggacgtggtcatccaa gatgatgacgtggaatgcacgatggtggagaagcgggtgctggccctgcccgggaagccg cccttcctgacccagctgcattcctgcttccagaccatggatcgcctgtactttgtgatg gagtatgtgaatggtggtgacctcatgtaccacatccagcaagtgggccggttcaaggag cctcacgccgtattttacgctgcagaaattgccatcggtctgttcttcttgcagagcaag ggcatcatttaccgtgacctgaaacttgacaatgtgatgctggattccgagggccacatc aagatcgctgattttggcatgtgtaaggagaacatctgggatggggtgacgactaagacc ttctgcggcaccccagactacatcgcccccgagataattgcttatcagccctatgggaag tccgtggattggtgggcatttggcgtcctgctgtatgagatgttggctgggcaggcaccg tttgaaggggaggacgaggatgaactcttccagtccatcatggaacacaacgtggcttat ccgaagtccatgtccaaggaagctgtggccatctgcaaagggctgatcaccaaacaccca ggcaaacgtctgggttgtggacctgaaggtgaacgtgacatcaaagagcatgcatttttc cggtatattgactgggagaaacttgaacgcaaagagattcagcccccgtataagccgaaa gcctgtgggcgaaatgctgaaaacttcgaccgatttttcacccgccatccaccagttcta acacctcctgaccaggaagtcatcaggaatattgaccaatcagaattcgaaggattttcc tttgttaactctgaatttttaaaacctgaagtcaagagctaa

DBGET integrated database retrieval system