Bos taurus (cow): 3283886
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Entry
3283886 CDS
T01008
Symbol
ND4
Name
(RefSeq) NADH dehydrogenase subunit 4
KO
K03881
NADH-ubiquinone oxidoreductase chain 4 [EC:
7.1.1.2
]
Organism
bta
Bos taurus (cow)
Pathway
bta00190
Oxidative phosphorylation
bta01100
Metabolic pathways
bta04714
Thermogenesis
bta04723
Retrograde endocannabinoid signaling
bta05010
Alzheimer disease
bta05012
Parkinson disease
bta05014
Amyotrophic lateral sclerosis
bta05016
Huntington disease
bta05020
Prion disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05208
Chemical carcinogenesis - reactive oxygen species
bta05415
Diabetic cardiomyopathy
Module
bta_M00142
NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
3283886 (ND4)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
3283886 (ND4)
09159 Environmental adaptation
04714 Thermogenesis
3283886 (ND4)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
3283886 (ND4)
09164 Neurodegenerative disease
05010 Alzheimer disease
3283886 (ND4)
05012 Parkinson disease
3283886 (ND4)
05014 Amyotrophic lateral sclerosis
3283886 (ND4)
05016 Huntington disease
3283886 (ND4)
05020 Prion disease
3283886 (ND4)
05022 Pathways of neurodegeneration - multiple diseases
3283886 (ND4)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
3283886 (ND4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
bta03029
]
3283886 (ND4)
Enzymes [BR:
bta01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
3283886 (ND4)
Mitochondrial biogenesis [BR:
bta03029
]
Mitochondrial DNA transcription, translation, and replication factors
Mitochondrial DNA-encoded proteins
Mitochondrial respiratory chain complex I
3283886 (ND4)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Proton_antipo_M
Oxidored_q5_N
Motif
Other DBs
NCBI-GeneID:
3283886
NCBI-ProteinID:
YP_209214
UniProt:
P03910
Q7JAS7
Structure
PDB
PDBj
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Position
MT
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AA seq
459 aa
AA seq
DB search
MLKYIIPTIMLMPLTWLSKNNMIWVNSTAHSLLISFTSLLLMNQFGDNSLNFSLLFFSDS
LSTPLLILTMWLLPLMLMASQHHLSKENLTRKKLFITMLISLQLFLIMTFTAMELILFYI
LFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALIYIQNTVGSLNFLMLQ
YWVQPVHNSWSNVFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGG
YGMLRITLILNPMTDFMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVA
ILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWL
LASLTNLALPPTINLIGELFVVMSTFSWSNITIILMGVNMVITALYSLYMLIMTQRGKYT
YHINNISPSFTRENALMSLHILPLLLLTLNPKIILGPLY
NT seq
1378 nt
NT seq
+upstream
nt +downstream
nt
atgctaaaatacattattccaacaattatacttatacccctaacctggttatcaaaaaat
aatataatttgggttaactccacagcacacagccttctaattagctttacaagcctcctc
ctcataaaccagtttggcgacaacagccttaatttttcactactatttttctccgactcc
ctatccactccactactaattttaaccatatggctcctccctctaatactaatagctagc
caacatcatctatcaaaagaaaacctaacccgaaaaaaactatttattactatgctgatc
tcactacaactattcctaattataacctttaccgccatggaactaatcttattttatatt
ctatttgaagcaacactagtcccaacactcattattattacccgatgaggaaaccaaaca
gaacgcctaaacgccggactctatttcctattctatacactagctggctccctaccccta
ttagtcgcactaatttatatccaaaacacagtaggatccctaaatttcctaatattacag
tactgagtacaacctgttcataactcttgatctaatgtcttcatatgactagcatgtata
atagctttcatagtaaaaataccactatatggcctccacctttgactacctaaagctcac
gtagaagcccccatcgcaggctccatagtccttgcagcagttctgctaaaactagggggg
tacggtatgctacgaatcacactaattctaaaccctatgaccgactttatagcataccca
ttcattatactctccctatgaggcataattataaccagctcaatctgcctccgtcaaacg
gacctaaaatcactcatcgcatactcctctgtaagccacatagcactcgttatcgtagcc
atccttatccagacaccttgaagctacataggagcaaccgcccttatgattgcccacggc
ctcacatcctccatacttttctgtctagcaaactcaaactacgaacgaatccacagccga
accataattctagctcgaggcctacaaacgctccttccactaatagccacctgatgacta
ctagcaagtctaaccaacttagctctacccccaacaatcaacttaattggagaactattt
gtagtaatgtcaaccttttcatgatctaacattacaattattctaataggagtaaatata
gtaatcaccgccctatattctctatacatgctaattataacccaacgaggaaaatatacc
taccacattaataatatctcgccttcctttacacgggaaaatgcactcatatcattacac
atcctacccctactactcctaaccctaaacccaaaaattattctaggacctctatact
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