Bos taurus (cow): 415113
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Entry
415113 CDS
T01008
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP precursor
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
bta
Bos taurus (cow)
Pathway
bta03060
Protein export
bta04141
Protein processing in endoplasmic reticulum
bta04156
Integrated stress response (ISR) signaling pathway
bta04612
Antigen processing and presentation
bta04918
Thyroid hormone synthesis
bta05012
Parkinson disease
bta05014
Amyotrophic lateral sclerosis
bta05020
Prion disease
bta05022
Pathways of neurodegeneration - multiple diseases
bta05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
415113 (HSPA5)
04141 Protein processing in endoplasmic reticulum
415113 (HSPA5)
09140 Cellular Processes
09143 Cell growth and death
04156 Integrated stress response (ISR) signaling pathway
415113 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
415113 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
415113 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
415113 (HSPA5)
05014 Amyotrophic lateral sclerosis
415113 (HSPA5)
05020 Prion disease
415113 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
415113 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
415113 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
bta03110
]
415113 (HSPA5)
04131 Membrane trafficking [BR:
bta04131
]
415113 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
bta04147
]
415113 (HSPA5)
Enzymes [BR:
bta01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
415113 (HSPA5)
Chaperones and folding catalysts [BR:
bta03110
]
Heat shock proteins
HSP70 / DNAK
415113 (HSPA5)
Membrane trafficking [BR:
bta04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
415113 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
415113 (HSPA5)
Exosome [BR:
bta04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
415113 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
415113 (HSPA5)
Exosomal proteins of colorectal cancer cells
415113 (HSPA5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
FGGY_C
DDR
Motif
Other DBs
NCBI-GeneID:
415113
NCBI-ProteinID:
NP_001068616
Ensembl:
ENSBTAG00000007662
VGNC:
59220
UniProt:
Q0VCX2
LinkDB
All DBs
Position
11
Genome browser
AA seq
655 aa
AA seq
DB search
MKLSLVAAVLLLLLGTARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTSEEEAADKDEL
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgtccctggtggctgcggtgctgctgctgctgcttggcacggcacgcgcggag
gaggaggacaagaaggaggacgtgggcacggtggtcggcatcgacctgggtaccacctac
tcctgcgtcggggtgttcaagaacggccgcgtggagatcatcgccaacgatcaaggcaac
cgcatcacgccgtcttatgtggctttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatccggagaacacagtcttcgacgccaagcgactcatc
ggccggacgtggaatgacccgtccgtgcagcaggacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccatacattcaagttgatgttggaggtgggcaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcatatttcaatgatgcc
caacgccaggcaaccaaagatgctggaactattgctggactgaatgtcatgaggatcatc
aatgagcctacagcagctgctattgcttatggcctggataagagggaaggggagaagaac
atcctggtgtttgacctgggtggtggaacctttgatgtgtctcttctcaccattgataat
ggtgtctttgaagtcgtggccactaatggagatactcatctgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttcgg
aaggacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctg
tcttcccaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctcg
gagaccctgactcgggctaaatttgaagagctaaacatggacctgttccgttccaccatg
aagcctgtccagaaagtgttggaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactagaatcccaaagattcaacagctggttaaagagtttttt
aatggcaaggagccatcccgtggcataaacccagatgaggctgtggcatatggtgccgct
gtccaggctggtgtgctctctggtgatcaagatacaggtgacctggtactgcttgatgta
tgtcccctgacacttggtattgaaactgtgggaggtgtcatgaccaaattgattccaagg
aacactgtggtgcccaccaagaagtctcagatcttttctacagcctctgataatcaacca
actgttaccatcaaggtctatgaaggtgaacgacccctgacgaaagacaatcaccttctg
ggaactttcgacctgactggaattcctcctgcaccccgtggggtcccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaa
agaatggtcaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcatc
gacacaagaaatgaattggaaagctatgcctactctcttaagaatcagattggagataaa
gaaaaactgggaggtaaactttcctcagaagataaggagaccatggaaaaagctgtagaa
gaaaagattgagtggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaa
aagaaggagctagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
cctcccccaaccagtgaggaggaagcagcagacaaagatgagttgtag
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