Bos taurus (cow): 505427
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Entry
505427 CDS
T01008
Symbol
MAP3K12
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 12
KO
K04423
mitogen-activated protein kinase kinase kinase 12 [EC:
2.7.11.25
]
Organism
bta
Bos taurus (cow)
Pathway
bta04010
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
505427 (MAP3K12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bta01001
]
505427 (MAP3K12)
Enzymes [BR:
bta01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
505427 (MAP3K12)
Protein kinases [BR:
bta01001
]
Serine/threonine kinases: TKL group
MLK family
505427 (MAP3K12)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Pkinase_fungal
ABC1
DUF7044
Motif
Other DBs
NCBI-GeneID:
505427
NCBI-ProteinID:
NP_001192220
Ensembl:
ENSBTAG00000020758
VGNC:
31190
UniProt:
A7E2Y8
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Position
5:26525840..26540452
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AA seq
860 aa
AA seq
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MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTHVLQLHEQDAGGPGG
ATGSPESRASRVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEV
PFEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVC
TQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSP
NMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVL
WELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQI
LLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELR
HALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKSHPSRGL
LHGNTMEKLIKKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCAKGPPSPGRS
RRGKTRHRKASAKGSCGDLPGLRAAVPPHEPGGPGSPVGLGGGPSAWEACPPALRGLHHD
LLLRKMSSSSPDLLSAALGARGRGATGGAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGG
AKGEPPPPVGPGDSVGLLGTGREGTAGRGGSRAGSQHLTPAALLYRAAVTRSQKRGISSE
EEEGEVDSEVELASSQRWPQGLKMRQSLSTFSSENPSDGEEGTASEPSPSGTPEVGSTNT
DERPDERSDDMCSQGSEIPLDPPASEVVTGPEPSSLPVPHHDLLRGEQGPPNPEDSDCDS
TELDNANSGEALRPPASLPP
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atggcctgcctccatgagacccgcacaccctccccttcctttgggggtttcgtgtccacc
ctaagcgaggcatccatgcgcaagctggacccagacacttccgactgcacccccgagaag
gacctgacgcccacccatgtcctgcagctccacgagcaggatgcagggggcccaggggga
gccactgggtcccctgagagtcgggcgtccagggtccgagcggatgaggtacggctccag
tgccagagcggcagcggcttcctggagggcctcttcggctgcctgcgccctgtgtggacc
atgatcggcaaagcctactccacggagcacaagcagcagcaggaagacctttgggaggtc
ccctttgaggaaatcctggacctgcagtgggtgggctcaggggcccagggcgccgtcttc
ctggggcgcttccatggggaggaggtggctgtgaagaaggtgcgggacctgaaggaaact
gacatcaagcacctgcgaaagctgaagcacccaaacatcatcaccttcaagggtgtgtgc
acccaggctccctgctactgcatcctcatggagttctgcgcccagggccagctgtacgag
gtgctgcgggctggccgccccgtcacgccctccttgctggttgactggtccatgggcatc
gccggcggcatgaactacctgcacctgcacaagattatccatcgggacctcaagtccccc
aacatgctaatcacctacgacgatgtggtgaagatctccgattttggcacttccaaggag
ctgagtgacaagagcaccaagatgtcctttgcagggacagtagcctggatggcccctgaa
gtgatccgcaacgaacctgtgtctgagaaggttgacatctggtcctttggcgtggtgctg
tgggagctgctgactggtgagatcccctacaaagacgtagattcctcagccatcatctgg
ggtgtgggaagcaacagtctccatctacctgtgccctccagctgcccagacggcttcaaa
atcctgcttcgccagtgctggaacagcaaaccacgaaaccgcccatcattccgacagatc
ctgctgcatctggacattgcctcagccgacgtactctccacaccccaggagacttacttt
aagtcccaggcagagtggcgtgaagaggtaaagctgcattttgaaaaaattaagtcagaa
gggacctgtctgcaccgcctagaagaggagctggtgatgcggaggagggaggagctcaga
catgccctggacattagggaacactatgagcggaaactggagagagccaacaacctgtac
atggaacttaatgcccttatgttgcagctggagctgaaggaacgggagctactcaggagg
gagcaagctttagagcggcggtgtccaggtctgctgaagtcacacccttcccggggcctg
ctgcacgggaacacgatggagaaactgatcaagaagaggaatgtcccacagaaactgtcg
ccccacagcaaaaggccagatatcctcaagactgagtctttgctacccaaactagatgca
gccctgagtggggtggggcttcctgggtgtgctaagggccccccctcaccaggacggagt
cgccgtggcaagactcgtcaccgcaaggccagcgccaagggcagctgtggggacctgcct
gggcttcgtgcagctgtgccaccccatgaacctgggggaccaggaagccccgtggggcta
ggcgggggaccctcagcctgggaagcctgccctccagccctccgtgggctccaccatgat
ctcctgctccgaaagatgtcttcatcatcgccagatctgctgtcagcagcattgggagcc
cggggccggggggctacagggggagctggggatcctggctcaccacctccagcccgggga
gacacgcccccaagcgagggctcagcacctggctccaccagcccggattcaccaggggga
gccaaaggggagccgcctccaccagtaggacctggtgacagtgtagggctgctgggaact
ggaagggaagggacggcgggacggggaggaagccgggctgggtcccagcacttgacccca
gccgcactgctgtacagggctgctgtcacccgaagtcagaaacgcggcatctcatcagag
gaagaggaaggagaggtggacagtgaagtggaactggcctcaagccagaggtggcctcag
ggcctgaaaatgcgccagtcactatctaccttcagctcagagaatccatcggatggggag
gagggcacagctagtgagccttcccccagtggcacacctgaagttggcagtaccaacaca
gatgagcggccggatgaacggtctgatgacatgtgctcgcagggctcagaaatcccactg
gacccaccagcttctgaggtggttactggcccagaacccagctccttgcccgtcccacac
cacgacctactcagaggggagcagggccctcccaaccctgaggactcagactgtgacagc
actgaactggacaacgccaacagcggtgaagccttgcggcccccagcctccctccctccg
tga
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