Bos taurus (cow): 506061
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Entry
506061 CDS
T01008
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
bta
Bos taurus (cow)
Pathway
bta00230
Purine metabolism
bta01100
Metabolic pathways
bta04024
cAMP signaling pathway
bta05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
506061 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
506061 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
506061 (PDE10A)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
506061 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
506061 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
506061
NCBI-ProteinID:
XP_024852899
BGD-bta:
BT14207
Ensembl:
ENSBTAG00000007758
VGNC:
32668
UniProt:
A0A3Q1MHJ4
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All DBs
Position
9:complement(100463057..101037653)
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AA seq
1068 aa
AA seq
DB search
MASPEEPLAPRPQAPLPAAGDEPGSGKLRPEPGRSAAGGRSAAGPGPAPEPPGRGRAERA
WSPRPPPSSAGRASPPGGPGALSARGGGGGWVAARAPFALAFSSPVRASAPSSFYFWPPP
PQPPPSLLPSSSAFHLPARLPGREGAAAAAAAARGGGGDAGGGGGQEAAPLSVPPSRSHR
GGGGGRRRLFLSPALRGLLLSARAGPRPPPPPRLPLGPAAPRAGSRGFPGAGGGCPAPGP
GPGPSPGGGGRTARRPRGAGAALAAAFPLLFASDMEDGPSNNASCFRRLTECFLSPNLTD
EKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNKKSEDESAPKEVSRYQDTNMQGVVY
ELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFIPPGIKEGK
PKLIPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTA
IGDLIGILELYRHWGKEAFRLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDV
SKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVF
KKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG
SVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLS
YHSICTAEEWQGLMHFNLPGRLCKEIELFHFDVGPFENMWPGIFVYMIHRSCGTACFELE
KLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNSRGLFTDLERKGLLIACLCHDLD
HRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEII
RKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTR
LTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFP
ATEPLLKACRNNLSQWEKVIRGEESALGIPDLPEAEGSPERLPVKTDD
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgaagagccacttgctccccgcccccaggcccccctgcccgcggcgggg
gacgagcccggctccggcaaactccgcccggagcccgggcgcagcgccgccggcgggagg
agcgcagcgggcccgggcccggcccccgagccgcctggtcgcggccgggccgagcgcgcc
tggtccccgcgcccgcccccctcttccgctggccgcgccagccccccggggggccccggc
gccctgtctgcgcgcggcggcgggggcggctgggtcgcagcgcgcgctcccttcgcgctc
gccttctcctccccggtccgcgcctccgctccatcttccttttacttctggccgccgccc
ccccaacccccgccttctcttctcccctcctcatctgcttttcacctccccgcgcgtctc
ccaggaagggagggcgcagcggcggcggcggcggcggcccgaggaggcggcggcgatgct
ggcggcggcggcggacaagaggcggctcccctgagcgtcccccccagcaggagtcaccgc
ggcggcggcggcgggcggcggcggctcttcctctcccccgcgctccgaggcttgctgctc
tcggcccgcgccgggccccggccgccgccgccgccccggctcccgctcggcccggccgcc
ccccgcgcgggttcccgcggcttcccgggcgccggcgggggctgccccgctccgggtccc
ggtcccggtcccagcccgggcggcggcggccgaacggcgcggcggcctcgaggcgccggc
gccgcgctcgccgccgcgttcccgctgctcttcgcctccgacatggaagatggaccttct
aataacgcgagctgcttccgaaggctgacggagtgtttcctgagccccaatttgacagat
gaaaaagtgaaggcctatctttctctccaccctcaggttttagatgaatttgtgtctgaa
agcgttagtgcagagactgtagaaaaatggctgaagcggaaaaacaagaagtcagaagat
gaatcagctcctaaggaagtcagcaggtatcaagatacaaatatgcaaggagttgtgtat
gaactaaatagctatatagaacagcggttggatacaggaggagacaaccagctactcctc
tatgaactgagcagcatcatcaaaatcgccacaaaagctgacggatttgcactgtatttc
cttggagagtgcaataacagcctttgtgtgtttatcccgcctggaatcaaggaaggaaaa
cccaagctcatccccgctggtcccatcgcccagggcaccaccacctctgcctatgtggcc
aagtccaggaaaacattgctggtggaagacatcctcggcgatgaacggtttccaagaggt
accgggctggaatcggggacgcgaatccagtctgtgctgtgtttgccgatcgtcactgcg
attggggacttgattggcatcctggagctctaccggcactggggcaaagaagccttccgt
ctgagtcaccaggaggttgcgacggcgaatcttgcctgggcttcagtagccatacaccag
gtgcaggtttgcagaggtcttgccaaacagactgaactgaatgactttctactcgacgta
tcaaaaacctattttgataacatagttgcaatagattctctacttgaacacataatgata
tatgcaaaaaacctggtgaatgccgaccgttgtgcccttttccaggtagaccataagaac
aaggagttatattcagacctttttgatattggagaggaaaaggaaggaaagcccgtcttc
aagaagaccaaggagatcaggttttcaatcgagaaggggatcgctggccaggtagcaagg
accggggaagttctgaacatcccagatgcctatgcagacccgcgcttcaacagagaggtg
gacttgtacacgggctacacgacccggaacatcctgtgcatgccgatcgtcagccgtggc
agcgtcattggcgtggtgcagatggtcaacaagctcagcggcagcgccttctccaagacg
gacgagaacaacttcaagatgtttgctgtcttctgtgctttagccttacactgtgccaac
atgtaccacaggatccggcactcggagtgcatctacagggtcacgatggagaagctgtcc
taccacagcatctgcaccgcggaggagtggcaaggcctcatgcacttcaacctgcccggc
cgtctgtgcaaagagatcgagctgttccactttgacgttggcccctttgaaaacatgtgg
cctggaattttcgtgtacatgatccaccgatcctgtgggacagcctgcttcgagctggag
aagttgtgccgtttcatcatgtctgtgaagaagaactaccgccgggttccttaccacaac
tggaagcacgcggtgacggtggcccactgcatgtacgccatcctgcagaacagccgcggg
ctcttcaccgacctcgagcgcaaagggctgctcatcgcgtgtctgtgccacgacctggac
caccggggattcagcaacagctacctgcagaagttcgaccacccgctggctgcgctctac
tccacgtccaccatggagcagcaccacttctcgcagaccgtgtccatcctgcagttggaa
ggacacaacatcttctccaccctgagctccagtgaatacgagcaggtgcttgagatcatc
cgcaaagccatcatcgccacggacctcgctctgtacttcgggaaccggaagcagctggaa
gagatgtaccagaccgggtcgctgaaccttaataaccaatcacatagagaccgtgtcatc
ggtttgatgatgaccgcctgtgatctttgttctgtgacaaagctgtggccagtgacgaga
ctgacggccaacgacatatatgcagaattctgggcggagggcgatgaaatgaagaaactg
gggatacagcccattcccatgatggacagagacaagaaggacgaggtcccgcaaggccag
ctggggttctacaatgccgtggccattccctgctacaccaccctcacccagatcttccct
gccacggaaccgctcctgaaggcctgcaggaataacctgagccagtgggagaaggtgatc
cggggcgaggagagcgccctggggatcccggacctgccagaggccgaggggtccccagag
aggctgcccgtgaagaccgatgactga
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