KEGG   Bos taurus (cow): 506093
Entry
506093            CDS       T01008                                 
Symbol
GSTT4
Name
(RefSeq) glutathione S-transferase, theta 4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
bta  Bos taurus (cow)
Pathway
bta00480  Glutathione metabolism
bta00980  Metabolism of xenobiotics by cytochrome P450
bta00982  Drug metabolism - cytochrome P450
bta00983  Drug metabolism - other enzymes
bta01100  Metabolic pathways
bta01524  Platinum drug resistance
bta05200  Pathways in cancer
bta05204  Chemical carcinogenesis - DNA adducts
bta05207  Chemical carcinogenesis - receptor activation
bta05208  Chemical carcinogenesis - reactive oxygen species
bta05225  Hepatocellular carcinoma
bta05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    506093 (GSTT4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    506093 (GSTT4)
   00982 Drug metabolism - cytochrome P450
    506093 (GSTT4)
   00983 Drug metabolism - other enzymes
    506093 (GSTT4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    506093 (GSTT4)
   05204 Chemical carcinogenesis - DNA adducts
    506093 (GSTT4)
   05207 Chemical carcinogenesis - receptor activation
    506093 (GSTT4)
   05208 Chemical carcinogenesis - reactive oxygen species
    506093 (GSTT4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    506093 (GSTT4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    506093 (GSTT4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    506093 (GSTT4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:bta02000]
    506093 (GSTT4)
Enzymes [BR:bta01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     506093 (GSTT4)
Transporters [BR:bta02000]
 Other transporters
  Pores ion channels [TC:1]
   506093 (GSTT4)
SSDB
Motif
Pfam: GST_N_3 GST_N GST_N_2 GST_C GST_C_3 GST_C_2 GST_C_7 DUF6589 GST_N_4
Other DBs
NCBI-GeneID: 506093
NCBI-ProteinID: NP_001193552
BGD-bta: BT23239
Ensembl: ENSBTAG00000000170
LinkDB
Position
17:71306063..71316088
AA seq 241 aa
MGLELYLDLLSPSCRAVYIFARKNSIPFDFQFVDLLKGHHHSREYIEINPLRKLPSLRDG
KFILSESVAILFYLCRKYSAPSHWYPPDLHMRARVDEFMAWQHTAIQLPMNKILWMKLLI
PMITGDEVPAEKTEQMLAEVKNNLKLFEEKFLQDKMFITGDNISLADLVALVEMMQPMAG
NHNVFLNSAKLAEWRMRVELAIGSTLFCEAHDRLVKLAEWDCSTLDPMVKERICDLLQKF
K
NT seq 726 nt   +upstreamnt  +downstreamnt
atgggcctggagctctacctggacctgctgtccccgtcctgccgcgccgtctacatcttc
gccaggaagaacagcatccccttcgacttccagtttgtggatctgctgaaaggtcaccac
cacagcagggagtacatcgagatcaaccccctgaggaagctgcccagcctcagagacggg
aagttcatcttgtctgaaagcgtggccatccttttctacctgtgccgcaagtacagcgcc
ccctcgcactggtacccgccagacctgcacatgcgtgcccgcgtggacgagttcatggcc
tggcagcacacggccattcagctgcccatgaacaagatactctggatgaagctgctgatc
ccgatgatcacgggagacgaggtcccagctgagaagacggagcagatgctggcggaggtg
aagaacaacctgaagctcttcgaggagaagtttctgcaggacaagatgttcatcactggg
gacaacatctccctggccgacctggtagccctggtggagatgatgcagcccatggccggc
aaccataacgtcttcctcaacagtgccaagctggccgagtggcgcatgagggtggagctg
gccatcggctccaccctcttctgcgaggcccacgaccggctggtgaagttggcggaatgg
gactgctccacactggacccgatggtcaaggagaggatctgcgatttgctgcagaagttc
aagtag

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