Bos taurus (cow): 506343
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Entry
506343 CDS
T01008
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
bta
Bos taurus (cow)
Pathway
bta00230
Purine metabolism
bta00670
One carbon pool by folate
bta01100
Metabolic pathways
bta01523
Antifolate resistance
Module
bta_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
506343 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
506343 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
506343 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
bta04147
]
506343 (ATIC)
Enzymes [BR:
bta01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
506343 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
506343 (ATIC)
Exosome [BR:
bta04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
506343 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
506343
NCBI-ProteinID:
NP_001068722
Ensembl:
ENSBTAG00000019274
VGNC:
26264
UniProt:
Q0VCK0
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Position
2:103327789..103350913
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AA seq
592 aa
AA seq
DB search
MAPGQLALFSVSDKNGLVEFARNLASVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARDIPEDSADMAKLDFNLIRVVVCNLYPFGKTVASPGVTVEEA
VEHIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVASEMQDSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKEYSKGVSQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGLPAAASFKHVSPAGAAVGIPLSEDEANVCMVYDLYKTLTPVA
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYENEALKILSKKKNG
NYCVLQMDQSYIPDENEVRTLFGLRLSQKRNNSVVNRSLFSNIVTKNKDLPESALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANCWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEGEDLIKWKALFEEVPELLTETEKKEWIDKLNEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgctttatttagtgtctctgacaaaaatggccttgtggagttt
gccaggaacttagcttctgtcggtttgaatctgatcgcctctggagggactgcaaaagcc
ctcagagatgctggtttggcagtcagagatgtctctgagctaactggatttcctgaaatg
ctaggggggcgtgtaaaaaccttgcatcctgcagtccatgctggaatcttggctcgtgat
atcccagaagatagtgctgacatggccaaacttgatttcaatcttataagagttgttgtt
tgtaatctgtatccctttgggaagacagtggcttctccaggtgtaactgttgaagaggct
gttgaacatattgatattggaggagtgactctgctgagagcagcagccaaaaaccacgct
cgagtgacagtagtatgtgagccggaggactatgcagctgtagcctcagagatgcaggat
tctgacagcaaagacacgtccttggagacaagacgccagttagccttgaaggcttttact
catacagcacagtatgatgaagcaatttcagattacttcaggaaagagtacagtaaagga
gtatctcagatgcccctgaggtatggaatgaaccctcatcagactcctgcccagctgtat
acgctgaagcccaagctccctatcacagttctgaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggccttcca
gctgctgcgtctttcaaacatgttagcccagcaggtgctgctgttggaattccactcagt
gaagacgaagccaacgtctgcatggtctatgatctgtacaaaaccctcacacccgtagcc
actgcatacgcaagagcaagaggggctgataggatgtcttcctttggtgactttgttgca
ttatctgatgtttgtgatgtccctactgccaagattatctccagagaggtatctgatggt
attattgccccgggatatgaaaatgaagctttgaaaatactttccaaaaagaaaaatggt
aattactgtgttcttcagatggaccagtcttatattccagacgaaaatgaagttcgaact
ctctttggtcttcgtttaagccagaagagaaataatagtgttgtcaacaggtcactgttt
agcaacattgttaccaagaataaagatttgccagaatctgcgctcagggacctcatcgtg
gccaccattgctgtcaagtacacccagtcgaactccgtgtgctatgccaagaatgggcag
gttattggcatcggagcaggacagcagtctcgtatacactgcacacgccttgcaggtgat
aaggcaaactgttggtggcttagacatcacccccaagtgctttccatgaagtttaaaact
ggcgtgaagagagcggaaatctccaatgccatcgatcagtatgttactggaactatcggc
gagggtgaagatttgatcaagtggaaggcactgtttgaggaggtccctgagttgttaacc
gagacagaaaaaaaggaatggattgacaaacttaatgaagtttccatcagctctgatgcc
ttctttcctttccgggacaatgtagacagagctaaaaggagtggcgtggcctacatcgct
gccccttccggttctgccgctgacaaagttgtgatcgaggcttgcgatgagctgggaata
atccttgctcatacgaatctccggctcttccatcactga
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