Bos taurus (cow): 507197
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Entry
507197 CDS
T01008
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial precursor
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
bta
Bos taurus (cow)
Pathway
bta00260
Glycine, serine and threonine metabolism
bta00630
Glyoxylate and dicarboxylate metabolism
bta00670
One carbon pool by folate
bta01100
Metabolic pathways
bta01200
Carbon metabolism
bta01230
Biosynthesis of amino acids
bta01240
Biosynthesis of cofactors
bta01523
Antifolate resistance
bta04981
Folate transport and metabolism
Module
bta_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
507197 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
507197 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
507197 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
507197 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
507197 (SHMT2)
Enzymes [BR:
bta01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
507197 (SHMT2)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
507197
NCBI-ProteinID:
NP_001029454
BGD-bta:
BT30382
Ensembl:
ENSBTAG00000031500
VGNC:
34604
UniProt:
Q3SZ20
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Position
5:complement(56208140..56216259)
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AA seq
504 aa
AA seq
DB search
MLSFSFIWATRPLRRCGQLVGMAVRCQHSEAAQTQTGEASKGWSGQESLSDSDPEMWELL
RREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLALTARLFKPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQILKNAQA
MANALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRGFLEDDFRKVVGFIDEGVNIGLEVKSKTTKLQDFKSFLLKDPETSH
QLADLRQRVEQFARAFPMPGFDDH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgttgtccttctcttttatttgggcgactcggcctctgcggagatgtggtcagctggtt
gggatggccgtacggtgccagcacagtgaggcggcccagactcagactggagaagcaagc
aagggctggtcaggccaggagagtctatcagacagtgaccctgagatgtgggagctgctg
cggagagagaaggacaggcagtgtcgcggcctggagctcattgcttcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacggaggagcagaggtagtggatgagatagagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgctcagtggggagtcaatgtccaaccc
tactccggatccccagccaatctggctgcctacacagcccttctgcagcctcacgaccga
atcatggggctggacttgcccgatgggggccatctcacccacggctacatgtctgatgtc
aagcggatctcagctacatctatcttcttcgagtctatgccttataagctgaacccccaa
accggcctcattgactatgaccagctggcactcactgctcggctcttcaaaccacgactc
atcatagctggtaccagtgcctatgctcgtctcattgactacgcccgcatgagagaagtg
tgtgacgaggtcaaggcacacctcttggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacccttcaagcacgcggatattgtcaccacgaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggggtgcaggctgtggac
cccaaaactggccgagagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcaggggggcccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcctgcacccccatgttccgggagtactccctgcagattctaaagaacgctcaggcc
atggctaatgccctgctggagcgaggctactccctggtgtctggtggcactgacaaccac
ctagtgctggtagaccttcggccaaagggcctggacggagctcgagcagaacgggtgttg
gaacttgtatccatcacggccaacaagaacacctgtcctggagatcgaagtgccatcacc
cctgggggcctgaggctgggggccccagccctgacttctcgagggttccttgaagatgac
ttccggaaagttgtaggctttatagatgaaggtgtcaacattggcttggaagtgaagagc
aagaccaccaaactccaggatttcaaatctttcctgctcaaagacccagaaacaagtcat
cagctggccgaccttaggcaacgggtggagcagttcgccagggccttccccatgcctggt
tttgatgatcactga
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