Bos taurus (cow): 509002
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Entry
509002 CDS
T01008
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
bta
Bos taurus (cow)
Pathway
bta00260
Glycine, serine and threonine metabolism
bta00630
Glyoxylate and dicarboxylate metabolism
bta00670
One carbon pool by folate
bta01100
Metabolic pathways
bta01200
Carbon metabolism
bta01230
Biosynthesis of amino acids
bta01240
Biosynthesis of cofactors
bta01523
Antifolate resistance
bta04981
Folate transport and metabolism
Module
bta_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
509002 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
509002 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
509002 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
509002 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
509002 (SHMT1)
Enzymes [BR:
bta01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
509002 (SHMT1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
509002
NCBI-ProteinID:
NP_001015553
BGD-bta:
BT29538
Ensembl:
ENSBTAG00000017094
VGNC:
34603
UniProt:
Q5E9P9
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Position
19:34321399..34350214
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AA seq
484 aa
AA seq
DB search
MAAPVNKAPRDANLWSLHEKMLAQPLKDNDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDSQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPRLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHVSGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGRETRYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRAYQRQVVANCRALAEALMGLGYRVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQK
VAHFIHRGIELTLQIQDAVGVKATLKEFMEKLAGAEEHHRAVAALRAEVESFATLFPLPG
LPGF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcagctccagtcaacaaggcacccagagatgccaatttgtggtccttgcacgagaag
atgctggcacagcccctgaaggacaacgatgtcgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggactggagctgatcgcctccgagaactttgccagccgggct
gttctggaggccctaggctcttgcctgaacaacaagtactctgaggggtacccaggccag
aggtactatggtgggacggagttcatcgacgagctagaggtcctctgtcagaagcgagcg
ctgcaggtctatggcctggactcccagtgctggggggttaacgtccagccttactcaggc
tccccagcaaacttcgcagtgtacacggccctggtggagccccatggccgcatcatgggc
ctggacctgccagatgggggccacctgacccatgggttcatgactgacaagaagaagatt
tctgccacgtccatcttttttgaatctatgccctacaaggtgaatcccgataccggctac
atcaactacgaccagctggaggagaacgcccgcctcttccacccgaggctgatcattgct
gggactagctgctactcccggaacctggactacgctcggctgcgcaagatcgctgatgac
aacggggcgtacctcatggccgacatggcacatgtcagtgggctggtggcggccggcgtg
gtgccttcgcccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcgg
ggctgccgcgccggcatgatcttctacaggaagggagtgcgcagtgtggaccccaagaca
ggcagagagactcgctacaacctggagtcgctcatcaactctgctgtgttcccaggcctg
caagggggaccccacaaccacgccattgctggggtcgcggttgctctgaagcaggccatg
actccagaattcagagcctaccagcgccaggtggtggccaactgcagggctctggccgag
gccttgatgggactgggctacagagtggtcacagggggttctgacaaccacttgatcctc
gtggacctccgctccaaaggcacagatggcggcagggcagagaaagtgctggaagcctgc
tccattgcctgcaataagaacacctgcccaggtgataaaagcgcgctacggcccagtggg
ctgcgcctggggaccccagcattgacctcccgagggctcttggaagaagatttccaaaag
gtcgcccatttcattcacagaggcatagagctgaccctgcagatccaggacgccgtaggg
gtgaaggccaccctgaaggagttcatggagaagctggcaggggccgaggagcaccatcgg
gccgtggcggccctcagggcagaggtggagagcttcgccaccctattcccgctgcctggc
ctgcctggcttctag
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