Bos taurus (cow): 512222
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Entry
512222 CDS
T01008
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
bta
Bos taurus (cow)
Pathway
bta00230
Purine metabolism
bta01100
Metabolic pathways
bta04024
cAMP signaling pathway
bta04928
Parathyroid hormone synthesis, secretion and action
bta05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
512222 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
512222 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
512222 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
512222 (PDE4A)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
512222 (PDE4A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Emfourin
Motif
Other DBs
NCBI-GeneID:
512222
NCBI-ProteinID:
NP_001094551
Ensembl:
ENSBTAG00000012032
VGNC:
55071
UniProt:
A6QQQ0
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Position
7:14946358..14990839
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AA seq
635 aa
AA seq
DB search
MPLVDFFCETCSKPWLVGWWDQFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKRNEVE
IPSPTIKDREKQQAPRQRPCQQPPAPGPQLQPMSQITGVKKLMHSSSLNDSSMPRFGVKT
DQEERLAQELENLNKWGLNIFRVSDYAGGRSLSCIMYTIFQERDLLKKFRIPVDTMVTYM
LTLEDHYHPDVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPG
VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKRQRQSLRKMVID
MVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPL
ELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWAD
LVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEEPGGPGHPPPPDKFQFELTLDEEEEE
EVCTAPGAVAIQELYMAQDASPPEDPLEVDGQDPSAEVEIEEMYLTRQVDSTGSVAAGQD
VSVPQGASVDVCVGCRNIPALSPNSLAPLALRTPPPPEDDPGLLGLPSMAAEVGAQKEHQ
AAKRACCACTGTAGEDPTPGALPAPGAWGSAGGPT
NT seq
1908 nt
NT seq
+upstream
nt +downstream
nt
atgcccttggtggatttcttctgcgagacctgctccaagccgtggctggtgggctggtgg
gaccagttcaagaggatgctaaaccgtgaactcacacacctgtcagagatgagcaggtca
ggaaaccaggtctctgagtacatctccaccacattcctggacaagcggaatgaagtggag
atcccatcacccacgatcaaagatcgggagaaacagcaagcgccacggcagagaccttgc
cagcagcccccggcccctgggccacagcttcagcccatgtctcagataaccggagtgaag
aagctgatgcatagcagcagcctcaacgattccagcatgccccgctttggtgtgaagact
gatcaagaggaacgcctagcccaagaactggaaaacctgaacaagtggggcctgaacatc
tttcgcgtgtcagattacgctggggggcgttccctcagctgtatcatgtacacaatattc
caggagcgggacctgctgaagaagttccgcatcccggtggacactatggtgacatacatg
ctgaccctagaggaccactaccacccggatgtggcttaccacaacagcctgcacgcagcc
gacgtgctgcagtccacccatgtgctgctggccacacctgcgttggatgccgtgtttacg
gacctggagattctcgctgccctcttcgcggctgccatccacgacgtggaccaccctgga
gtctccaatcagttcctcattaacaccaattcagaactggcgctcatgtacaacgacgag
tcggtgctggaaaatcaccacctggccgtgggcttcaagctgctgcaggaagacaactgt
gacatcttccagaacctcggcaagcgccagcggcagagcctgcgcaagatggtcatcgac
atggtgctggccacggatatgtccaagcacatgaccctcctggctgacctgaagaccatg
gtggagactaagaaagtgaccagctcaggggtcctcttgctggataactattccgaccgc
atccaggttctacggaacatggtgcactgcgcagaccttagcaaccccaccaagccgctg
gagctttaccgccagtggactgaccgcatcatggccgagttcttccagcagggcgaccgt
gaacgtgagcgaggcatggagatcagtcccatgtgcgacaagcacacagcctcagtggag
aagtctcaggtgggtttcattgactatatcgtacacccgctgtgggagacgtgggctgac
ttggtccacccagatgcccaagagatcctggacactctggaagacaaccgggactggtac
tacagcgccattcggcagagcccctcgccaccccccgaggaggagcctgggggaccgggc
caccccccaccacctgataagttccagttcgagctgacgctggacgaggaagaggaggag
gaggtgtgcactgccccgggtgcggttgcaattcaggaattgtacatggcccaggatgcc
tccccacctgaagaccctttggaagttgatggccaggatccatctgcggaggtggagata
gaggaaatgtacttgacccggcaagtggactccacaggtagtgtggcagctggccaggac
gtgtccgtgccccaaggcgcgtccgtggatgtctgtgtgggctgccgcaacatccctgcc
ctgtctcctaatagccttgctccgcttgccttgaggacaccgccccctccagaggacgac
ccgggccttctgggcctcccctccatggcagccgaggtgggggcccaaaaagagcatcag
gctgccaagagggcatgctgtgcctgcacggggacagccggcgaggatcccactcctgga
gcgcttccagctcccggagcttgggggtcagctggtggccctacctga
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