Bos taurus (cow): 515710
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Entry
515710 CDS
T01008
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
bta
Bos taurus (cow)
Pathway
bta00140
Steroid hormone biosynthesis
bta01100
Metabolic pathways
bta04913
Ovarian steroidogenesis
Module
bta_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
515710 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
515710 (HSD17B2)
Enzymes [BR:
bta01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
515710 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
515710 (HSD17B2)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
Peptidase_S49
Motif
Other DBs
NCBI-GeneID:
515710
NCBI-ProteinID:
NP_001069194
BGD-bta:
BT16216
Ensembl:
ENSBTAG00000003234
VGNC:
29973
UniProt:
Q0PHW6
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Position
18:8586361..8679831
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AA seq
388 aa
AA seq
DB search
MGTFFSEPGWLFLTVTAVLGGTILCKLKTSPGQVGRKVVCLAGLWGGACLISLSLFWGLV
LFSLSYFVMYTYFSGQELLPVDQKAVLITGCDSGFGHGLAKYLDELGFTVFAGVLDEQGS
GAEELRRTCSKNLSVLQLNITNTQEIKAAYSKVKEKLQNKGLWAVINNAGVLGLPTDGEL
IPMTEYKRCMAVNFFGAVEVTKVFLPLLRKSKGRLVNISSMAGGVPMQKMAAYGSSKAAL
IMFSSILRQELSKWGVKVSVIQPGGFKTNISGTSQMWEKLERTVLDNLSPEVQEDYGQDY
ILSERSFLNLMKTSTDPDISPVLLDVRHAISAQSPFAFYAPGKLSYPWLCFASISPTGIF
DYLSRKIHTYSKKMPRVLSTSNWENEAM
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgggcactttcttctctgagcctgggtggctcttcctgactgtcaccgcagtgctggga
ggaacaattctttgcaaactcaagactagcccagggcaggtggggagaaaggtggtctgc
ctggcgggcctctggggaggcgcttgcctgatcagcctgtccctcttctggggcttggtc
ctcttctccctgtcgtatttcgtcatgtatacttacttttctggccaagagttgttacct
gtggatcaaaaggcggtgctgataacaggttgtgattctgggtttggccatggtttggcc
aagtatctggacgagctgggcttcactgtatttgccggagttctggatgaacaggggtct
ggagcagaggaattacgaagaacctgctccaagaatctctctgtgctccagctgaacatc
accaacacgcaggagataaaagcggcctacagcaaagtgaaggagaagctgcagaacaaa
ggactgtgggctgtgatcaacaacgctggagtccttggcttaccaaccgatggggaactc
attcccatgaccgaatacaaacgatgcatggccgtgaacttcttcggggctgtggaagtc
acgaaggtgttcctgcctcttcttagaaaatccaaggggaggctggtgaatatcagcagc
atggcaggaggggttccaatgcagaagatggcagcctatggctcatccaaggcagctctg
atcatgttttcatcaatcctgcgacaagagctgtccaaatggggagttaaagtctctgtc
atccagcccggaggcttcaaaacaaacatctcaggcacgagtcaaatgtgggagaagctg
gagaggactgtcctggacaacctttcccctgaagtgcaagaggactacggccaggactat
atccttagcgaacgtagttttctcaacttaatgaaaacctccactgatccagacatctcc
ccagtgctcctggacgttcggcacgccatctctgctcagagcccctttgcattttatgcg
ccggggaaattgtcttatccgtggctctgttttgcttccatcagccctactggcatattt
gattatcttagcagaaaaatacatacctacagtaagaagatgcccagagtgttaagcaca
tctaactgggagaatgaggctatgtag
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