Bos taurus (cow): 515718
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Entry
515718 CDS
T01008
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
bta
Bos taurus (cow)
Pathway
bta04015
Rap1 signaling pathway
bta04024
cAMP signaling pathway
bta04062
Chemokine signaling pathway
bta04510
Focal adhesion
bta04650
Natural killer cell mediated cytotoxicity
bta04660
T cell receptor signaling pathway
bta04662
B cell receptor signaling pathway
bta04664
Fc epsilon RI signaling pathway
bta04666
Fc gamma R-mediated phagocytosis
bta04670
Leukocyte transendothelial migration
bta04810
Regulation of actin cytoskeleton
bta05135
Yersinia infection
bta05205
Proteoglycans in cancer
bta05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
515718 (VAV2)
04024 cAMP signaling pathway
515718 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
515718 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
515718 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
515718 (VAV2)
04660 T cell receptor signaling pathway
515718 (VAV2)
04662 B cell receptor signaling pathway
515718 (VAV2)
04664 Fc epsilon RI signaling pathway
515718 (VAV2)
04666 Fc gamma R-mediated phagocytosis
515718 (VAV2)
04670 Leukocyte transendothelial migration
515718 (VAV2)
04062 Chemokine signaling pathway
515718 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
515718 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
515718 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
515718 (VAV2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
PH
C1_1
DUF7145
RHG20_PH
PLU-1
CDC24
C1_2
SH2_2
PH_10
zf-RING_16
zf-RING-like
ANC1_spectrin
Motif
Other DBs
NCBI-GeneID:
515718
NCBI-ProteinID:
XP_024855427
Ensembl:
ENSBTAG00000004511
VGNC:
36773
LinkDB
All DBs
Position
11:complement(104589753..104778037)
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AA seq
874 aa
AA seq
DB search
MEQWRQCGRWLIDCRVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDV
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSDLFDPFDLFDVRDFGKVISAVSRLSLHSL
AQNKGIRPFPSEETTENDEDVYRSLEELADEHGVGEDIYDCVPCEDDGDDIYEDIIKVEV
QQPMKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYVTPLRLVLSPVDMAAIFINLE
DLIKVHHSFLRAIDVSMMAGGSSLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASRE
DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR
YLFLFDKVVIVCKRRGYSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQ
GKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACRMFLR
GTFYQGYLCTKCGVGAHKECLEVTPPCKISSPADPDASGAGPGPKMVAVQNYHGNPAPPT
KPALTFQTGDVIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPLSRE
MDYTAYPWFAGNMERQQTDNLLKPHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEK
DSWVHITEAKKFESLLELVEYYQYHSLKESFKQLDTTLKYPYKAWERTASRASSRSPASC
ASYNFSFLSPQGLGLASQGSSTPFWSAVFTPRVIGTAVARYNFAARDLRELSLREGDVVK
IYSRIGGDQGWWKGETSGRVGWFPSTYVEEEGVQ
NT seq
2625 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcaatgcggccgctggctcatcgactgcagggtcctgccgcccaac
caccgcgtcgtctggccctcggccgtggtcttcgacctggcccaggcgctgcgcgacggc
gtcctgttgtgccagctgctgcacaacctctcccccggctccatcgacctcaaggacgtc
aacttccggccgcagatgtcccagttcctctgcttgaagaacatccgcaccttcctgaaa
gtctgccatgacaagtttgggctcaggaacagcgatctgttcgacccctttgacctcttc
gatgtccgagacttcgggaaggtcatctccgccgtgtcaagactctccctgcacagcttg
gctcagaacaaaggcatcaggcccttcccctcggaggagaccacggagaatgacgaggac
gtgtaccgcagcctggaggagctggcagatgagcacggcgtgggagaggacatctatgac
tgcgtcccgtgcgaggatgacggggacgacatctatgaggacatcatcaaggtggaggtg
cagcagcccatgaaaatgggcatgacagaggatgacaagagaaactgctgcctgctggag
atccaggagacggaggccaagtactaccggacgctggaggacatcgagaagaactacgtg
acgcccctgaggctggtgctcagcccggtggacatggcggccatcttcatcaacctggag
gacctgattaaggtgcatcacagcttcctgagggccatcgacgtgtccatgatggcgggc
ggcagctcgctggccaaggtcttcctggacttcaaggagaggctcctaatctatggggag
tattgcagtcacatggagcacgcccagaacacactgaaccagctcctggccagcagggag
gacttcagacagaaagtcgaggaatgcaccctgaaggtccaggacgggaagttcaagctg
caggacctgctggtggtccccatgcagagggtactcaaataccacctgctcctcaaggaa
cttctgagccattccaccgaccggccggagaggcagcagctcaaagaagcgctggaggcc
atgcaggacttggccatgtacataaacgaagttaaacgggacaaagagaccctgaagaaa
atcagcgaatttcagagctctatagaaaacttgcaagtgaaactggaggaattcgggaga
ccgaagatcgacggggagctgaaggtccggtccatagtcaaccacaccaagcaagacagg
tacctgttcctgtttgacaaggtggtcatcgtctgcaagaggaggggctacagctacgag
ctgaaggagatcatagagctgctcttccacaagatgaccgacgaccccatgaacaacaag
gacgtcaagaagtctcacgggaagatgtggtcctacggcttctatctcattcacctacaa
ggcaagcaaggcttccagtttttctgcaagacagaggacatgaagaggaagtggatggag
cagtttgagatggccatgtcaaacatcaagcccgacaaggccaacgccaaccaccacagc
ttccagatgtacacgttcgacaagaccaccaactgcaaagcctgccgcatgttcctcagg
ggtactttctaccagggttacctctgcaccaagtgtggcgtcggggcgcacaaggagtgt
ctggaagtgacccctccctgcaagatcagttctcctgcagacccggatgcctctggagcg
gggccaggtcccaagatggtggccgtgcagaattaccatggcaaccccgctccccccacg
aagccggcgctgaccttccagacgggcgatgtgatcgagctgctgagaggcgaccccgag
tctcagtggtgggagggtcggctggtgcagaccaggaagtcaggctacttccccagctcg
tctgtgaagccctgtcctgtggatggaaggccacccatcagccggccgctgtcccgggag
atggactacacggcatacccctggtttgccggaaatatggagaggcagcagaccgacaac
ctgctcaaaccccacgccagcgggacctacctaatcagggagcggccggcggaggccgag
cgctttgccataagtatcaagttcaacgacgaggtgaagcacattaaggtggtggagaag
gacagctgggtccacatcacagaagccaagaaatttgagagcctcttggagctggtggag
tactaccagtaccactcgctcaaggagagcttcaagcagctggacaccacactcaagtac
ccgtacaaggcctgggaacgcacagcctccagggcctccagccgctccccagcttcctgc
gcttcctacaacttttcttttctcagtcctcagggcctcggccttgcttctcagggctcc
tccacacccttctggtcagcagtgttcacaccccgtgtcatcggcacggccgtggccagg
tacaacttcgccgcccgcgacctgcgggagctctcgctgcgggaaggtgacgtggtgaag
atatacagccgcatcggcggggaccagggctggtggaagggcgagaccagcggccgggtc
ggctggtttccttcaacgtatgtagaagaggagggcgtccagtga
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