KEGG   Bos taurus (cow): 516175
Entry
516175            CDS       T01008                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
bta  Bos taurus (cow)
Pathway
bta03015  mRNA surveillance pathway
bta04022  cGMP-PKG signaling pathway
bta04024  cAMP signaling pathway
bta04114  Oocyte meiosis
bta04218  Cellular senescence
bta04261  Adrenergic signaling in cardiomyocytes
bta04270  Vascular smooth muscle contraction
bta04390  Hippo signaling pathway
bta04510  Focal adhesion
bta04611  Platelet activation
bta04720  Long-term potentiation
bta04728  Dopaminergic synapse
bta04750  Inflammatory mediator regulation of TRP channels
bta04810  Regulation of actin cytoskeleton
bta04910  Insulin signaling pathway
bta04921  Oxytocin signaling pathway
bta04931  Insulin resistance
bta05031  Amphetamine addiction
bta05034  Alcoholism
bta05168  Herpes simplex virus 1 infection
bta05205  Proteoglycans in cancer
bta05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    516175 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    516175 (PPP1CA)
   04024 cAMP signaling pathway
    516175 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    516175 (PPP1CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    516175 (PPP1CA)
   04218 Cellular senescence
    516175 (PPP1CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    516175 (PPP1CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    516175 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    516175 (PPP1CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    516175 (PPP1CA)
   04921 Oxytocin signaling pathway
    516175 (PPP1CA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    516175 (PPP1CA)
   04270 Vascular smooth muscle contraction
    516175 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    516175 (PPP1CA)
   04720 Long-term potentiation
    516175 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    516175 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    516175 (PPP1CA)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    516175 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    516175 (PPP1CA)
   05034 Alcoholism
    516175 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    516175 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    516175 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:bta01009]
    516175 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:bta03021]
    516175 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:bta03019]
    516175 (PPP1CA)
   03041 Spliceosome [BR:bta03041]
    516175 (PPP1CA)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     516175 (PPP1CA)
Protein phosphatases and associated proteins [BR:bta01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     516175 (PPP1CA)
Transcription machinery [BR:bta03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     516175 (PPP1CA)
Messenger RNA biogenesis [BR:bta03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     516175 (PPP1CA)
Spliceosome [BR:bta03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    516175 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 516175
NCBI-ProteinID: NP_001030393
BGD-bta: BT10197
Ensembl: ENSBTAG00000012146
VGNC: 106874
UniProt: Q3T0E7
LinkDB
Position
29:complement(45292436..45295867)
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactctataatcggacgcctgctggaagtgcag
ggctccaggcctggaaagaatgtacagctgacggagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacattcatggccagtactatgatcttctgcggctgttcgagtacggtggc
ttccctccagagagtaactacttgttcctgggggactacgtggacaggggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaagtacccagagaacttcttcctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgagtgc
aagagacgctacaacatcaaactgtggaagaccttcactgattgcttcaactgcctgccc
atcgctgccatcgtggacgagaagatcttctgttgccatggagggctgtccccagaccta
cagtccatggagcagatccggcgtatcatgcggcccacagatgtgcctgaccagggcctg
ctctgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggtgagaatgac
cgcggcgtctcctttacatttggagctgaggtggtggccaagttcctgcacaagcatgac
ctggacctcatctgccgggcacaccaggtagtagaagacggctatgagttctttgccaag
cggcagctggtgacactcttttcagcccccaactactgcggcgagtttgacaatgcaggt
gccatgatgagtgtggacgagacgctcatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaaatacgggcagttcagtggcctgaaccctggaggccggcccatcacc
ccaccccgcaactccgccaaagccaagaaatag

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