KEGG   Bos taurus (cow): 518075
Entry
518075            CDS       T01008                                 
Symbol
ATP7B
Name
(RefSeq) copper-transporting ATPase 2 isoform X1
  KO
K17686  P-type Cu+ transporter [EC:7.2.2.8]
Organism
bta  Bos taurus (cow)
Pathway
bta01524  Platinum drug resistance
bta04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:bta00001]
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    518075 (ATP7B)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    518075 (ATP7B)
Enzymes [BR:bta01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.8  P-type Cu+ transporter
     518075 (ATP7B)
SSDB
Motif
Pfam: HMA E1-E2_ATPase Hydrolase HMA_PCA1 Hydrolase_3 Hydrolase_6 HAD_2 HAD Zn_ribbon_DUF2089
Other DBs
NCBI-GeneID: 518075
NCBI-ProteinID: XP_002691840
BGD-bta: BT12155
Ensembl: ENSBTAG00000010353
VGNC: 26328
UniProt: F1MKI1
LinkDB
Position
12:complement(21341015..21415269)
AA seq 1505 aa
MERAGDQTPGNPEPSSLATLGDPQVTLLSVHKQWSFKRSPGTGGSSRPVISEEECPPPSE
EGEFSQKVLNGSEEISSKQILSKLSQPAMKQSFAFDNNGYEDDLDGVRPSHTATGTINIV
GMTCQSCVKSIEGRVSSLKGIVSIKVSLEQGSAEVRYVPSVVSLVQICHQIEDMGFQASV
AEGKATSWPSRVSPASEAMVKLRVEGMTCQSCVSSIEGKIGKLQGVLRVRVSLSNQEAVI
TYQPYLIQPQDLRDHITDMGFEAVIKNKVAPVSLGPIDVRRLQSTLSAAPPAPVNQNDNN
SETPGGQGIPLHLRVDGMHCKSCVLNIEDNIGRLPGVQSIHVSLESRTAQVQYDPSLVSP
GALQRAIEALPPGNFKVSLPNGVEGSGPDSRSPPASSAPCTVMLAIAGMTCKSCVQSIEG
LISQRAGVHQISVFLAEGTAVVLYDPSRTHPEELRAAVEDMGFEASILAENCSSNHIGNH
SSGSAVGHVAAGTPVPVQGGTPQPGELHTNHIPRQSPKSLPASTTVAPKKCFLQISGMTC
ASCVSNIERNLQKEPGILSVLVALMAGKAEVKYNPEAIQPLEIAKLIQDLGFEAAVMEDY
TGSDGDLELMITGMTCASCVHNIESKLRRTEGITYASVALATSKAHVKFDPEIIGPRDIV
KLIEEIGFRASLAQRIPNAHHLDHKVEIKQWKNSFLCSLVFGIPVMGLMIYMLIPSHEPQ
STVLDHNVIPGLSILNLIFFILCTFVQFLGGWYFYVQAYKSLRHGMANMDVLIVLATSVA
YVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHVVKSKTSEALAKLMSLQA
TEATVVTLGEDNVIIREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGE
AMPVTKKPGSMVIAGSMNAHGSVLVTATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRF
SGYFVPFIIIISTVTLVVWIGIGFTDFGVVQKYFPVPSKGISQAEVVLRFAFQTSITVLC
IACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPKVS
RVLLLVDVATLPLRKVLAVVGTAEASSEHPLGVAVTRYCKEELGTETLGCCTDFQAVPGC
GISCKVSSVESILAQGERLQGPLTTHLNRVGSNPTETDAATQTFSVLIGNREWMRRNGLT
VTSDVRDAMTDHEMKGQTAILVAIDGVLCGMIAIADSVKQEAALAVHTLKSMGVDVVLIT
GDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNQGKRVAMVGDGVNDSPALAQADV
GIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSRRTVWRIRLNLVLALIYNLIGIPVAA
GVFIPIGVVLQPWMGSAAMAASSVSVVLSSLQLKCYRKPDLARYEAQAHGSMKPLSASQV
SVRVGMDDRRRDSPRASAWDQVSYVSQVSLSPLKSDKLSRHSGAADDRGDKWSLLLNDRD
EEQGI
NT seq 4518 nt   +upstreamnt  +downstreamnt
atggagagagctggggaccagacgcccgggaaccccgagccatcctccctggcgactctg
ggtgacccacaggtgaccctgctatctgtccacaaacagtggtccttcaagaggagccct
gggaccgggggctccagcaggcccgtgatttcagaggaggaatgccctcccccgtcagag
gaaggagaattttcacagaaggttttgaatggatcggaagagatcagttccaagcagatc
ctgtctaagctctcccagccagcgatgaagcagagctttgcctttgacaacaatggctac
gaggatgacctggatggcgtgcgcccctcccacacggccactggcaccatcaacatcgtg
ggcatgacctgccagtcgtgtgtcaagtccatcgagggcagggtctccagtttgaaaggc
attgtgagcattaaggtttccctggagcagggcagcgctgaggtgaggtacgtgccctca
gtggtaagcctggtgcagatttgccatcagattgaagacatgggcttccaggccagtgtg
gctgagggaaaggccacctcctggccctccagggtctcacctgcctcagaggccatggtc
aaacttcgggtggagggcatgacctgccagtcctgtgtcagctccatagaaggcaagatc
gggaaactgcagggcgtcctgagggtccgtgtctcgctcagcaaccaggaggcagtcatc
acttaccagccttaccttatccaaccccaagacctcagggaccacataactgacatggga
tttgaagccgtcatcaagaacaaggtggcccccgtgagcctgggacccatagacgtcagg
cggctccagagcaccctctcagcagcccctccggctcccgttaatcagaatgacaataac
tctgagaccccggggggccaggggatccccctgcacctgagagtggatggaatgcactgt
aagtcttgtgtcctgaacattgaagacaatatcggccggctccccggggttcagagtatt
cacgtgtccctggagagcaggactgcccaagtccagtatgacccttctctcgtctcccca
ggggccctgcagagagccattgaggccctgcctcctgggaactttaaagtctctcttccc
aatggggtggaagggagtgggccagactccaggagccccccggcgtccagtgcgccctgt
accgtgatgctggccatcgccggcatgacctgcaagtcttgcgtccagtccatcgaaggc
ctgatctcccagagggcgggtgtgcaccagatctcagtctttttggccgaagggactgca
gtggttctctacgatccatctcgaactcacccagaagaactgcgagctgcggtggaggac
atgggattcgaggcctccatcctggctgaaaactgttccagcaaccacattggcaaccac
agctctgggagtgccgtggggcacgtggcggctggcacacctgtgcctgtgcagggaggg
actccccagccaggggagctccatactaaccacatcccccgccagtcgcccaagtccctg
ccggcctccaccacggtggccccaaagaagtgcttcctacagatctcaggcatgacctgt
gcatcctgtgtgtccaacatagagaggaacctgcagaaagaacctgggatcctgtccgtg
ctggttgccctgatggcgggaaaggcagaggtgaagtacaacccggaagccatccagccc
ctggagatagcaaagctcatccaggacctgggctttgaggcagcagtgatggaagactac
acgggctcggatggtgacctcgagctgatgatcacagggatgacctgcgcctcctgtgtt
cacaacatagaatccaaactcaggaggacagaaggcatcacctacgcctctgtggctctc
gccaccagcaaagcccacgtgaagtttgatcctgaaattattggtccgcgggacattgtc
aaactcatcgaggaaattggctttcgtgcctccctggcccagaggatccccaatgctcat
cacttggaccacaaggtggaaataaagcagtggaagaactctttcctgtgcagcctggtg
tttggcatccccgtcatgggtttaatgatctatatgttgatacccagccatgagccccag
tcgacggtcctggaccacaacgtcatcccaggactgtccatcctgaatctcatcttcttt
atcttgtgcacctttgtccagttcctcggcggctggtacttctatgtccaggcctacaaa
tctctgagacacgggatggccaacatggacgtgctcatcgtgctggccacgagcgtcgcc
tatgtctactccctcgtcatcctggtggtggccgtggccgagaaggccgagaggagcccc
gtgaccttctttgacacgccccccatgctcttcgtcttcattgccctggggcggtggctg
gaacacgtggtgaagagcaaaacctcagaagcgcttgccaaactcatgtctctgcaagcc
acggaagccaccgtcgtgacccttggtgaagacaacgtgatcatcagggaggagcaggtg
cccatggagctggtgcaacgaggtgacatcatcaaggtggtccccgggggcaagtttccc
gtggacgggaaagtcctagaaggcaacaccatggccgacgagtccctcatcacaggagag
gccatgcctgtcaccaagaagcccggaagcatggtaattgccgggtccatgaacgcccat
ggctctgtgctcgtcactgccacccacgtgggcaatgatacgaccttggcccagattgtg
aagctagtggaagaggcccagatgtccaaggcacccattcagcaactggctgaccggttt
agtggatattttgtcccatttatcatcatcatttcaactgtgacgttggtggtatggatt
ggtatcggttttaccgattttggtgttgttcagaaatactttcctgtccccagcaagggt
atctcccaggcagaggtggtcctgcggttcgcgttccagacgtccatcacggtgctctgc
atcgcctgcccctgctcgctgggcctggccacacccacggccgtcatggtgggcaccggg
gtggccgcccagaacggcatcctcatcaagggaggcaagcccctggagatggcccacaag
ataaagaccgtgatgttcgacaaaaccggcaccattacccacggggtccccaaagtctca
cgggtcctcctgctcgtggacgtggccacgctgcccctgcggaaggtgctcgctgtggtg
gggactgcagaggccagcagcgagcaccccctgggcgtggcagtcaccagatactgtaaa
gaggaacttggcacggagaccctggggtgctgcacggactttcaggcagtgcccggctgt
ggaatcagctgcaaagtcagcagcgtggagagcatcctcgcccaaggcgagcgcctgcaa
ggcccactgaccactcacctgaacagagtcggcagcaaccccacagaaacagacgcggcc
acgcagaccttctctgtgctgatcggaaaccgggaatggatgaggcgcaatggcctgacc
gttaccagcgacgtccgcgacgccatgaccgaccacgagatgaagggccagacagccatc
ctggtggccatcgatggtgtgctgtgcggtatgatcgccatcgcggactcggtcaagcag
gaggccgccctggccgtgcacacgctgaagagcatgggcgtggacgtggtgctcatcacc
ggggacaaccgcaagacagccagggccatcgccacccaggtcggcatcaacaaagtcttt
gcggaggtgctgccttctcacaaggtggccaaggtccaggagctgcagaaccaggggaag
agagtggccatggtgggcgacggtgtgaacgactccccagccctggcacaggctgacgtg
ggcattgccattggcacgggcactgacgtggccatcgaggcggccgacgtcgtcctcatc
aggaatgacctgctggatgtggtggccagcattcacctctccaggaggaccgtctggaga
atacggctcaacctggtgctggcgctgatctacaacctgatcgggatccccgtcgcggca
ggtgtcttcatacccattggtgttgtgctgcagccgtggatgggctcggcggccatggcg
gcctcctctgtgtctgtggtcctctcgtcactgcagctcaagtgctacaggaagccggac
ctggcgcggtacgaggcgcaggcgcacggcagcatgaagcctctgagcgcgtcccaggtc
agcgtgcgcgtcggcatggacgaccgccggcgtgactccccgcgggcctcggcctgggac
caggtcagctacgtcagccaggtgtccctgtcccccctcaagtccgacaagctgtcccgg
cacagtggcgcggccgatgacaggggcgacaagtggtctctgctcctgaatgaccgggac
gaggagcagggcatctga

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