Bos taurus (cow): 520318
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Entry
520318 CDS
T01008
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
bta
Bos taurus (cow)
Pathway
bta00230
Purine metabolism
bta01100
Metabolic pathways
Module
bta_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
520318 (PFAS)
Enzymes [BR:
bta01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
520318 (PFAS)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
520318
NCBI-ProteinID:
NP_001243493
BGD-bta:
BT29024
Ensembl:
ENSBTAG00000031509
VGNC:
32765
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All DBs
Position
19:27880011..27899172
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AA seq
1338 aa
AA seq
DB search
MSSVLHFYVRPSGHERAASEYIQRKLQRELPELQGVKTEQCYNVNWAAESFPSNKEMKKL
TWLFGCPLLLDDVAQESWLRPGPTDLLLEVGPRLNFSTPTSSNIVSVCQAAGLGAVDRVE
PTRRYLLSFAHPPSADLEAIALATLHDRMTEQHFPQPIQSFSSGCIPAPLSGPIDVLAEG
RSALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEVFDLAQSNSEHSRHWFFKGRLH
VDGQELPHSLFESIMSTQASSNPNNVLKFCDNSSAIQGKEVRFLRPKDPTRPSSFQQCQG
LRHVVFTAETHNFPTGVAPFSGAATGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
SMPWEDPSFQYPGNFARPLEIAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAEHVSKEPPETGMDVVKIGGPVYRIGVGGGAASSVQVQGDNASDLD
FGAVQRGDPEMEQKMNRVIRACVEAPGGNPICSLHDQGAGGNGNVLKELSDPAGAVIHTS
CFQLGDPTLNALEIWGAEYQESNALLLRPSDRDFLSCVSARERCPVCFVGTITGDRRIVL
VDDREWPMGTGGQVDAPPTPPPTPVDLDLDWVLGKMPQKEFFLQRSLPLLQPLTLPPGLS
VRQALARVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHQELVG
AATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLQDVKCSGNWMWAAKLPGEGAA
LADACEAMVAVMAALGVAVDGGKDSLSMAARVGSETVRAPGSLVISAYAVCSDITATVTP
DLKRPGGRGHLLYVPLSPGQHRLGGTALAQCFSQLGEQPPDLDVPENLVRAFSITQGLLK
DRLLCSGHDVSDGGLITCLLEMAFAGNCGIEVDIPAPGVDALPVLFAEEPGLVLEVQEPD
LAQVLMRYRNAGLHCLELGLTGDTGPHAMVRVSVNRTVVLEEPVGQLRALWEETSFQLDR
LQAKPHCVAQEEQGLRERAGPTFCLPPTFPRASVPCEPGGPAPRVAIIREEGSNGDREMA
DAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFNPQAG
AEMKRFRQRPDTFSLGVCNGCQLLALLGWVGGSSSEEVVEMCQESWPARPGLLLRHNLSG
RFESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQMEARGLAPLHWA
DDDGNPTEQYPLNPNGSPGGVAGICSPDGRHLALMPHPERSVRPWQWAWRPPPFDTLTTS
PWLQLFINARNWTQECSC
NT seq
4017 nt
NT seq
+upstream
nt +downstream
nt
atgtcctccgtccttcacttctatgtccgcccctctggccacgagagggcagcctctgaa
tacattcaaaggaagctgcaaagggaactgccagagctgcagggtgtcaagaccgagcag
tgctacaatgtgaactgggcagcggagtccttcccgagcaacaaggagatgaagaagctg
acatggctatttggctgccccttgttactggacgatgttgctcaggaatcctggcttcgt
cctggccccacagacctgctgctggaggtcggacccaggctgaacttttccaccccgaca
tccagcaacattgtgtcagtgtgccaggctgcagggctgggggctgtggaccgcgtggag
ccaacccggcgctacctgctctcgtttgcccacccaccttcagctgacctggaggccatt
gccctggctaccctgcatgaccggatgacagagcagcacttcccccagcccatccagagc
ttctcttcagggtgcatcccagcacccctgagcggcccaattgacgtgctggctgagggc
cggtctgccctggagaaagccaaccaggagctaggtctggccctagactcctgggacctg
gatttctacaccaagcgcttccaggagctgcagcgcaaccccagcactgtggaagtcttc
gacttggctcagtccaatagcgaacacagccgacactggttcttcaagggtcgactccat
gtggatggacaggagctgccacactcgctgtttgagtccatcatgagcacccaggcgtcc
tccaaccctaacaacgtcctcaagttctgtgacaacagcagtgccatccaggggaaagaa
gtccgattcttgcggcctaaggaccccacacggccaagctccttccagcaatgtcagggg
ctgagacatgttgtcttcacagcagagacacacaacttccctacaggagtagcccccttc
agtggtgcagccactggcacagggggccggatccgagatgtccagtgcacaggccgaggg
gcccacgtggtggctggcactgctggctattgctttggaaacctgcacatcccaggttac
agtatgccctgggaggatccaagcttccagtatccaggaaactttgcccgacccctggag
attgccattgaggccagtaatggggcttctgactacggcaacaagtttggggaaccagtg
cttgctggctttgcccgctccttgggccttcagcttccggacggccagcggcgtgagtgg
atcaagcccataatgtttagtggaggcattgggtccatggaagctgagcatgtgagcaag
gagcccccagagacaggcatggatgtcgtgaagattggcggtcctgtctacaggattgga
gttgggggcggagctgcttcgtctgtgcaggtgcaaggagacaacgccagtgacctggat
tttggggctgtgcagcggggagacccagagatggagcagaagatgaaccgtgtgatccgg
gcttgtgtggaggcccctgggggaaaccccatctgcagcctccatgaccagggtgctggt
ggcaatggcaatgtcctgaaggagctgagtgacccggctggagccgtcattcacaccagc
tgcttccagctgggggacccaaccctgaatgccctggaaatctggggggccgagtaccag
gagtcgaacgcacttctgctgaggccctctgaccgggacttcctgagttgtgtcagcgcc
cgggaacgctgcccagtctgctttgtgggcaccatcactggagacaggagaatagtgctg
gtggatgatcgggagtggcctatgggcacaggtggccaggtggatgcgccccccactcct
cccccaacccctgtggacctggacctggactgggtgctgggcaagatgccccagaaggag
ttcttcctccagaggagtctccccttgctgcagcctctgactctgcccccagggctgagc
gtgcgccaggctctggcgcgggtcctcaggctgcctgccgtggccagcaagcgctacctc
accaacaaggtggaccgttctgtgggcggcctggtggcccagcagcagtgtgtgggaccc
ctgcagacccctctggcagatgtggcggttgtggcactgagtcaccaggagcttgtaggg
gccgccacagccctgggagagcagccagtcaagagcctgctggacccgaaggttgccgcc
cggctggctgtggccgaagccctcaccaacctggtatttgctctggtcaccgacctccag
gatgtgaaatgcagcgggaactggatgtgggcagccaagctcccaggggagggtgcagct
ctggctgacgcctgtgaggctatggtggcagtgatggcggccctgggtgtagcggtagac
ggtggcaaggactccctcagcatggctgcccgggttggctctgaaaccgtgcgggctcct
gggtcactggtcatctcagcctatgctgtctgttcagacattacagccactgtgacccca
gacctcaagcgtcctggggggagaggccacctgctctacgtgcctctgagtcctgggcag
caccggctggggggcacagctctggctcagtgcttctcccagcttggcgagcagcctccc
gacctggatgttcctgagaacttggtgcgagccttcagcatcacccaggggctgctgaaa
gaccgcctcctctgctcaggccatgatgtcagtgatggaggtctcatcacttgcctgcta
gagatggcctttgctgggaattgtgggatagaggtggacatccccgcacctggggtcgat
gccctgcctgtgctgttcgccgaggagccaggcctggtgctggaggtgcaggagccggac
ctcgcccaagtgctgatgcgttaccggaatgctggcctccactgcctagagctgggtctc
acaggcgacacggggccccacgccatggtccgcgtgtcggtgaacaggacggtggttctg
gaggaacctgttgggcagctacgagccctctgggaggaaaccagtttccagttggaccgg
ctacaggcaaaaccacactgtgtggcccaggaagagcaagggctgagggagcgggcaggg
cccaccttctgcctgccgcctaccttccccagagcttccgtgccttgtgagcctggtggt
cctgccccccgagtcgccatcattcgggaagagggcagtaatggagaccgggagatggca
gatgccttccacttggctggatttgaggtgtgggatgtaaccatgcaggacctgtgctct
ggagccatcgggctggacacattccgcggtgtggccttcgtaggcggcttcagctacgcg
gacgtcctgggctctgccaaaggctgggcagctgctgtgacctttaacccgcaggccggg
gctgagatgaagcgcttccgccagcggccagacaccttcagcctgggcgtgtgtaacggc
tgtcagctgctggccctgctgggctgggtgggaggcagttctagtgaggaggtggtggag
atgtgccaggagtcctggccggcccggcccggtctcctgctacgccacaacctgtctggg
cgctttgagtcgcgctgggctagtgtgcgcgtggggcccgggccagccctgatgctgcga
gggatggaaggcgcggtgctgcccgtgtggagcgctcacggggaaggttacatggcattt
tcttctccggaactccaagcccagatggaggccaggggcttagctccactgcactgggca
gatgatgatgggaaccccacggaacagtaccccctgaatcccaacggctccccagggggt
gtcgctggcatctgctcccccgatggccgccacttggccctcatgcctcacccggagcgg
tctgtgaggccttggcagtgggcctggcgacctcctccatttgacactctaaccacctcc
ccctggctccagctcttcatcaatgcccggaattggacccaggaatgcagctgctaa
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