Bos taurus (cow): 524446
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Entry
524446 CDS
T01008
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
bta
Bos taurus (cow)
Pathway
bta00230
Purine metabolism
bta01100
Metabolic pathways
bta04934
Cushing syndrome
bta05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
524446 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
524446 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
524446 (PDE11A)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
524446 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
524446 (PDE11A)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
DUF4175
HD
Motif
Other DBs
NCBI-GeneID:
524446
NCBI-ProteinID:
NP_001192351
BGD-bta:
BT18975
Ensembl:
ENSBTAG00000016396
VGNC:
32669
UniProt:
E1BPD8
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All DBs
Position
2:18826605..19250049
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AA seq
926 aa
AA seq
DB search
MTASRLDFGEVETFLDRHPELLEDYLMRKGKQEMVEKWMQRHGQGQGAVGPRSTPAASTS
GGGGSGSPGPDGSASSQPTPGGGECRGGPMGPSWASGSRGDGSLQRRASQKELRKSFARS
KAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPT
AMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAA
GKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRF
NDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGI
AISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLL
EDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSVAELVASTGLPVNI
SDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFE
AFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAI
DDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRH
AFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYG
TSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFF
ELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERAE
LKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEEL
HQKRLLVSAAASAPSANVMETRDDRN
NT seq
2781 nt
NT seq
+upstream
nt +downstream
nt
atgacggcctcccgcctggactttggggaggtggaaactttcctggacaggcacccagag
ttgttggaagattacctgatgcggaaggggaagcaggagatggtggagaagtggatgcag
aggcacgggcagggtcaaggggctgtaggcccgaggtccaccccggccgccagcacgagc
ggtggcggaggcagcggcagccctggacccgacggctctgccagcagccagcccaccccg
ggcggtggggagtgtagggggggccccatgggtcccagctgggccagtggcagccggggc
gatgggagcctgcagcggagagcttctcagaaggagctgaggaagagttttgcccgctcc
aaggccatccatgtgaacaggacctacgacgaacaagtgacctcccgggcccaggagccc
ctgagcagtgtgcggcggagggcgcttctccggaaggccagctccctgcccccaaccacc
gcccacattctcagcgccctgctggaatcgcgggtgaatctgcctcagtacccccctacg
gccatggactacaagtgccacctcaaaaagcataacgagcgacagttcttcctggaactg
gtcaaagatatctccaatgaccttgaccttaccagtctgagctacaagatcctcatcttc
gtctgcctcatggtggacgcagaccgctgctctctcttcctggtggaaggggcggctgct
ggcaagaagagcctggtctccaaattctttgatgtgcatgcaggaaccccactgctgccc
tgcagcagcacagaaaactcaaacgaggtgcaggtcccttggggcaaaggtatcattggt
tatgtcggggagcatggagagacggtcaacattcctgatgcctaccaggatcgaagattc
aatgatgaaatcgacaagctaactgggtacaagacaaagtcattactgtgcatgcctatc
cgaagcagtgacggtgagatcatcggcgtggcccaagcgatcaataagattcctgagggt
gctccatttactgaagatgatgaaaaagtcatgcagatgtatcttccattttgtggaatc
gccatatccaatgctcagctctttgctgcctcaaggaaagaatatgaaagaagcagggct
ttgctagaggtggttaatgacctctttgaggaacagactgacctggagaaaattgtcaag
aaaataatgcatcgggcccaaacactgttgaaatgtgaacgctgttctgttttactcctg
gaggacatcgaatcaccagtggtgaagtttaccaaatcctttgaattgatgtccccaaag
tgcagtgctgacgctgagaacagtttcaaagaaagcatggagaaatcatcgtactctgat
tggctgataaataacagtgttgccgagctggtggcttccacgggccttccagtgaacatc
agtgatgcctaccaggatccccgctttgatgccgaggctgaccagatatctggttttcac
ataagatcagttctctgcgtacctatttggaatagcaaccaccaaataattggagtggct
caagtgttaaatagactcgatgggaaacctttcgatgatgccgatcaacgacttttcgag
gcttttgtcatcttttgtggccttggcatcaacaatacaattatgtacgatcaagtgaag
aagtcatgggccaagcagtccgtggctcttgatgtgctatcttatcatgcaacatgttca
aaagctgaagttgacaagtttaaggcagccaacatccccctggtgtcagaactcgccatc
gacgacatacattttgatgacttttctctcgacgttgacgccatgatcacggctgctctg
cggatgttcatggagctggggatggtacagaaatttaagattgactatgagacgctgtgt
aggtggctcctgacagtaaggaagaattaccgaatggtcctgtaccacaactggagacac
gccttcaacgtgtgccagctgatgtttgcgatgttgactaccgccgggtttcaagagatt
ctgaccgaggtggaaattttagcggtgattgtgggatgcctgtgtcatgacctcgaccac
aggggaaccaacaatgccttccaagctaagagtggctctgccctggcccaactctatgga
acctctgccaccttagagcatcaccatttcaaccatgcagtgatgatccttcagagcgag
ggtcacaacatctttgctaatttgtcctccaaggaatacagtgaccttatgcagcttttg
aagcagtcaatcctggcaacagacctcacgctgtactttgaaaggagaacggaattcttc
gaacttgtcagtaaaggagaatatgattggaacatcaaaaaccatcgtgatatatttcga
tcaatgttaatgacagcctgtgaccttggagccgtgaccaaaccgtgggagatctcgaga
caggtggctgaacttgtaaccagcgagttctttgaacaaggcgatcgggagagagcagaa
ctgaaactcaccccttcagctatttttgatcggaaccggaaggatgagctgcctcggttg
caactggagtggattgatagcatctgtatgcctttgtatcaggcattggtgaaggtcaat
gtgaaactgaagccaatgttggattccgtggccaccaacagaagtaagtgggaagagttg
caccagaaaaggctgctcgtctccgcagctgcctccgccccctccgccaacgtcatggag
accagggatgacagaaactaa
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